Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T22274 | Target Info | |||
| Target Name | Histone deacetylase 6 (HDAC6) | ||||
| Synonyms |
KIAA0901; JM21; HD6
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| Target Type | Clinical trial Target | ||||
| Gene Name | HDAC6 | ||||
| Biochemical Class | Carbon-nitrogen hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 137 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Imatinib
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|
Approved | Compound Info | ||
| Synonyms |
Cgp 57148; Glamox; Glamox (TN); Gleevec (TN); Glivec (TN); Imatinib (INN); Imatinib (STI571); Imatinib Methansulfonate; Imatinib [INN:BAN]; 112GI019; 152459-95-5; BKJ8M8G5HI; CCRIS 9076; CGP-57148; CHEMBL941; Imatinib free base; STI; UNII-BKJ8M8G5HI
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
SNDX-275
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|
Phase 3 | Compound Info | ||
| Synonyms |
Entinostat; Histone Deacetylase Inhibitor I; IN1470; MS 275; SNDX 275; MS 27-275; Ms-275; Entinostat (USAN/INN); MS-27-275; Pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate; Pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate; Pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester; Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester; Entinostat, SNDX-275, MS-27-275, MS-275; N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide; N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide; Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester; 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
Tacedinaline
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|
Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
Acetyldinaline; Tacedinalina; Goe 5549; PD 123654; Ci-994; Goe-5549; PD-123654; Tacedinalina [INN-Spanish]; Tacedinaline [USAN:INN]; C.I. 994; Tacedinaline (USAN/INN); 4-(Acetylamino)-N-(2-aminophenyl)benzamide; 4-acetamido-N-(2-aminophenyl)benzamide; 4-acetamido-n-(2-aminophenyl)benzamid; 4-acetylamino-N-(2'-aminophenyl)benzamide
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-(2-aminophenyl)nicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-(2-Amino-phenyl)-nicotinamide; 436089-31-5; N-(2-aminophenyl)nicotinamide; N-(2-aminophenyl)pyridine-3-carboxamide; CHEMBL236678; AC1LMN6K; SCHEMBL18086514; CTK4I7538; DTXSID50360661; CHEBI:125506; ZINC873967; BDBM50220259; 3463AE; AKOS000129725; RTR-042156; MCULE-7933541910; N-(2-aminophenyl)-3-pyridylcarboxamide; ZB014940; ACM436089315; ST086607; ASN 01337807; KB-298440; TR-042156; BC4148434; SR-01000329900; SR-01000329900-1; BRD-K20880473-001-04-6
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(4-hydroxybiphenyl-3-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL269935; N-(4-hydroxybiphenyl-3-yl)benzamide; SCHEMBL5724398; BDBM50232005
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
AZUMAMIDE E
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Investigative | Compound Info | ||
| Synonyms |
azumamide E; CHEMBL402363
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
AZUMAMIDE B
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|
Investigative | Compound Info | ||
| Synonyms |
AZUMAMIDE B; CHEMBL402727
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(4-aminobiphenyl-3-yl)nicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255805; N-(4-aminobiphenyl-3-yl)nicotinamide; BDBM50232035
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(4-aminobiphenyl-3-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-(4-aminobiphenyl-3-yl)benzamide; CHEMBL271741; 3max; SCHEMBL16380794; BDBM50232053; N-(4-amino-biphenyl-3-yl)-benzamide
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256440; N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide; SCHEMBL1066609
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
AZUMAMIDE C
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|
Investigative | Compound Info | ||
| Synonyms |
AZUMAMIDE C; CHEMBL257972
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(2-aminophenyl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-(2-aminophenyl)benzamide; 2'-AMINOBENZANILIDE; 721-47-1; CHEMBL405072; AC1LFSYX; AC1Q5NOK; ACMC-1AE0C; Oprea1_478192; MLS000084661; SCHEMBL407834; N-(2-amino-phenyl)-benzamide; AC1Q514U; Benzamide, N-(2-aminophenyl)-; CTK2H2825; DTXSID60353948; RFDVMOUXHKTCDO-UHFFFAOYSA-N; MolPort-001-783-352; ZINC225957; HMS2355D18; STL497474; BDBM50232046; AKOS000133162; MCULE-5545982713; NE17312; SMR000019009; TC-170926; KB-298435; ST51030142; EN300-31745; SR-01000389415; AE-641/00785046
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-hydroxy-4-(naphthalen-1-yl)benzamide
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|
Investigative | Compound Info | ||
| Synonyms |
N-Hydroxy-4-naphthalen-1-yl-benzamide
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| Activity |
IC50 = 55000 nM
|
[7] | |||
| Compound Name |
splitomicin
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Investigative | Compound Info | ||
| Synonyms |
splitomicin; 5690-03-9; 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one; 1,2-dihydro-3h-benzo[f]chromen-3-one; 1H-benzo[f]chromen-3(2H)-one; CHEMBL86537; CHEBI:75272; 1,2-dihydrobenzo[f]chromen-3-one; 1H,2H,3H-naphtho[2,1-b]pyran-3-one; Splitomycin; Bio2_000878; Tocris-1542; AC1L1JZ6; AC1Q6ML4; KBioGR_000456; BSPBio_001116; KBioSS_000456; GTPL8101; SCHEMBL2544804; ZINC27374; KBio3_000852; KBio2_003024; BDBM29590; KBio3_000851; KBio2_005592; KBio2_000456; MolPort-003-959-546; ISFPDBUKMJDAJH-UHFFFAOYSA-N; HMS1362H17; HMS1990H17; Bio2_000398
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| Activity |
IC50 ~ 75000 nM
|
[8] | |||
| Compound Name |
N-hydroxy-3-(naphthalen-1-yl)acrylamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL245548; N-hydroxy-3-(naphthalen-1-yl)acrylamide; SCHEMBL14106948; BDBM50207560; (E)-3-(1-Naphthalenyl)-2-propenehydroximic acid
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| Activity |
IC50 = 82000 nM
|
[7] | |||
| Compound Name |
N-hydroxy-1-naphthamide
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Investigative | Compound Info | ||
| Synonyms |
1-Naphthohydroxamic acid; 6953-61-3; N-Hydroxy-1-naphthamide; 1-NAPHTHALENECARBOXAMIDE, N-HYDROXY-; NSC 57457; N-Hydroxynaphthalene-1-carboxamide; alpha-Naphthohydroxamic acid; a-Naphthohydroxamic acid; BRN 2094470; CHEMBL115468; Naphthalene-1-carboxylic acid hydroxyamide; 8GK; naphthylhydroxamic acid; AC1L2M8D; N-Hydroxy-1-naphthamide #; 4-09-00-02407 (Beilstein Handbook Reference); .alpha.-Naphthohydroxamic acid; ACMC-209o98; SCHEMBL2230679; CTK5D0341; DTXSID30219789; JRZGPWOEHDOVMC-UHFFFAOYSA-N
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
Biphenyl-3-carboxylic acid hydroxyamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL154517; Biphenyl-3-carboxylic acid hydroxyamide; 3-biphenyl hydroxamic acid; 3-Phenylbenzohydroximic acid; SCHEMBL10363097; SEPGPMDDTZHYJV-UHFFFAOYSA-N; ZINC27646665
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| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047543; BDBM50386459
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Thiophene-2-carboxylic acid (4-hydroxy-biphenyl-3-yl)-amide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL398884; BDBM50229199
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|
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[4-(propylaminocarbamoyl)anilino]propan-2-yl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4063938; BDBM50244779
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
6-Methylquinoline-8-thiol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101230; 6-Methyl-8-mercaptochinolin; 8-Quinolinethiol, 6-methyl-; SCHEMBL18526845; BDBM50264491
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
3-(3-Bromo-4-methoxyphenyl)-N-(2-methylsulfanylethyl)-2-oxopropanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047672; BDBM50386464
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047676; BDBM50386433
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|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Carbamic acid,N-[[4-[[(4-amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]-,methyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL398420; Carbamic acid, N-[[4-[[(4-amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]-, methyl ester; SCHEMBL4314772; BDBM50229192; ZINC29039034; Methyl {4-[(4-amino-3-biphenylyl)carbamoyl]benzyl}carbamate; [4-(4-amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid methyl ester; methyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate; N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-(2-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104197; BDBM50235702
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-N-[2-[2-[[(2E)-3-(3-bromo-4-methoxyphenyl)-2-hydrazinylidenepropanoyl]amino]ethyldisulfanyl]ethyl]-2-hydrazinylidenepropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047679; BDBM50386471
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
Azumamide D
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL257973; BDBM50377382
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(2-methylphenyl)octanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080874; BDBM50235706
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|
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
Benzyl (2S)-4-[5-[(2-amino-5-phenylphenyl)carbamoyl]pyridin-2-yl]-2-methylpiperazine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL437029; SCHEMBL4534462; BDBM50374011
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
N-(7-Amino-7-oxoheptyl)-2-(N-phenylanilino)pyrimidine-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2223535; CHEMBL3640676; BDBM110103; ZINC118347164; DA-46086; FT-0755559; US8609678, N-(7-amino-7-oxoheptyl)-2-(diphenylamino)pyrimidine-5-carboxamide [156]
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| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
N-[4-(Dimethylamino)phenyl]-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066515; BDBM50235703
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
Benzamide-type inhibitor, 4
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL235674; SCHEMBL1066960; BDBM19412; pyridin-3-ylmethyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate; pyridin-3-ylmethyl N-[(4-{[2-amino-5-(thiophen-2-yl)phenyl]carbamoyl}phenyl)methyl]carbamate
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-(3-Chlorophenyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093113; BDBM50235705
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-hydroxyphenyl)-2-methoxyimino-N-(2-methylsulfanylethyl)propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047542; BDBM50386458
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
N-(2-Aminophenyl)-11-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]undecanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735995; RMS-162; BDBM50499398; J3.517.118E
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| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
N-Butyl-11-[(7R,8R,9S,13S,14S,17S)-3,17-dihydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-7-yl]-N-hydroxyundecanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3735187; RMS-234; BDBM50499399; J3.517.119C
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| Activity |
IC50 ~ 50000 nM
|
[14] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-(4-fluorophenyl)-N'-hydroxyoctanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079958; BDBM50235708
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
Ethyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL399494; SCHEMBL8101991; BDBM50229197; ethyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-2-hydrazinylidene-N-(2-methylsulfanylethyl)propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047677; BDBM50386469
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(4-methoxyphenyl)octanediamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095542; BDBM50235707
Click to Show/Hide
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
Methyl 4-((2-amino-5-(thiophen-2-yl)phenyl)carbamoyl)benzylcarbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL400721; SCHEMBL4323563; BDBM50229193; ZINC29039255; AKOS016360308; DA-16374; FT-0749974; methyl N-[[4-[(2-amino-5-thiophen-2-ylphenyl)carbamoyl]phenyl]methyl]carbamate
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
(2E)-3-(3-Bromo-4-methoxyphenyl)-N-[2-[2-[[(2E)-3-(3-bromo-4-methoxyphenyl)-2-methoxyiminopropanoyl]amino]ethyldisulfanyl]ethyl]-2-methoxyiminopropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047668; BDBM50386461
Click to Show/Hide
|
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
[4-(4-Amino-biphenyl-3-ylcarbamoyl)-benzyl]-carbamic acid pyridin-3-ylmethyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL253868; SCHEMBL3646556; BDBM50229189; SB19285; pyridin-3-ylmethyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate; pyridin-3-ylmethyl[(4-{[(4-aminobiphenyl-3-yl)amino]carbonyl}phenyl)methyl]carbamate
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
N-(2-Amino-5-(thiophen-2-yl)phenyl)-6-(2-oxo-1-oxa-3,8-diazaspiro[4.5]decan-8-yl)nicotinamide
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Investigative | Compound Info | ||
| Synonyms |
MRLB-223; CHEMBL3286732; SCHEMBL1639102; BDBM50016941
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| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
Diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL470225; SCHEMBL2208777; BDBM50278515; N-(2-amino-5-thiophen-2-ylphenyl)-4-[(diethoxyphosphorylmethylamino)methyl]benzamide; diethyl [({[4-({[2-amino-5-(2-thienyl)phenyl]amino) carbonyl}phenyl]methyl}amino)methyl]phosphonate
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
N-(2-Amino-5-thiophen-2-ylphenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL271949; SCHEMBL1067101; BDBM50374007
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Azumamide A
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL255714; BDBM50377385
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2,2,3,3,4,4,5,5,6,6,7,7-Dodecafluoro-N-hydroxy-N'-(3-methylphenyl)octanediamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098910; BDBM50235701
Click to Show/Hide
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
(S)-Benzyl 4-(5-(2-aminophenylcarbamoyl)pyridin-2-yl)-2-methylpiperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL236902; SCHEMBL4539214; BDBM50220232; (S)-benzyl 4-(5-((2-aminophenyl)carbamoyl)pyridin-2-yl)-2-methylpiperazine-1-carboxylate; benzyl (2S)-4-[5-[(2-aminophenyl)carbamoyl]pyridin-2-yl]-2-methylpiperazine-1-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
N1-(2-Aminophenyl)-N8-(biphenyl-3-yl)octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515285; BDBM50277215
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[18] | |||
| Compound Name |
(1R,3As,4E,7aR)-4-[2-[(3R,5R)-3,5-dihydroxycyclohexylidene]ethylidene]-7a-methyl-1-[(2R)-6-(sulfamoylamino)hexan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-indene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164241; SCHEMBL8006838; BDBM50320747
Click to Show/Hide
|
||||
| Activity |
IC50 = 50400 nM
|
[19] | |||
| Compound Name |
(4-Oxo[1]benzofuro[3,2-d]pyrimidin-3(4H)-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1708622; MLS000773791; SCHEMBL1520207; CTK7J5060; 2-(4-oxo-[1]benzofuro[3,2-d]pyrimidin-3-yl)acetic acid; HMS2756C16; ZINC4206575; BDBM50455902; SBB078221; AKOS000118231; MCULE-4732219556; NE24991; SMR000364673; EN300-13447; SR-01000069783; SR-01000069783-1; Z90120424; 2-(4-oxo-3-hydrobenzo[d]pyrimidino[5,4-b]furan-3-yl)acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[20] | |||
| Compound Name |
3-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethylamino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3982857; BDBM50210260
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[21] | |||
| Compound Name |
3-(5-Chloro-1,3-benzothiazol-2-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(5-Chloranyl-1,3-Benzothiazol-2-Yl)propanoic Acid; CHEMBL4069423; SCHEMBL16198162; CTK7J3143; ZINC4219237; BDBM50242196; AKOS000205646; MCULE-6107525772; EN300-71902; Q27456561; Z228584328
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[20] | |||
| Compound Name |
N-Hydroxy-5-[3-(pent-4-enoylamino)propyl]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2046611; BDBM50387311
Click to Show/Hide
|
||||
| Activity |
IC50 = 58670 nM
|
[22] | |||
| Compound Name |
3-[3-(Phenylsulfanyl)-2-quinoxalinyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4102489; BDBM50242197; ZINC96124726
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[23] | |||
| Compound Name |
(E)-N-(2-Aminophenyl)-3-[4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluorophenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3948452; BDBM50199119
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[24] | |||
| Compound Name |
2-[(4-Hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(4-methoxyphenyl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1307946; SMR000104980; CBMicro_000564; Oprea1_387281; Oprea1_513871; MLS000109033; REGID_for_CID_722456; HMS2167C19; HMS3314O04; SMSF0007972; ZINC8632101; BDBM50348374; STK927199; STL281551; AKOS000566015; AKOS002232718; AKOS008969277; CB01814; MCULE-2661039450; BIM-0000433.P001; ST50112774; AB00097791-01; AB00097791-06; SR-01000417195; SR-01000417195-1; 2-[2-(4-methoxyphenyl)-2-oxoethylthio]-6-methyl-3-hydropyrimidin-4-one; 2-{[2-(4-methoxyphenyl)-2-oxoethyl]sulfanyl}-6-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 60900 nM
|
[25] | |||
| Compound Name |
4-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethylamino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3954183; BDBM50210263
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[21] | |||
| Compound Name |
(R)-7-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)-N-methyl-2-oxooctanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164244; SCHEMBL8008665; BDBM50320739
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[19] | |||
| Compound Name |
3-(4-Methyl-3-oxo-3,4-dihydroquinoxalin-2-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(1-Methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)propionic acid; 3-(4-methyl-3-oxoquinoxalin-2-yl)propanoic acid; CHEMBL4068652; 2-Quinoxalinepropanoicacid, 3,4-dihydro-4-methyl-3-oxo-; 3-(4-methyl-3-oxo-4-hydroquinoxalin-2-yl)propanoic acid; NSC75194; SCHEMBL11428310; CTK0I2997; DTXSID90933873; KS-00002AN3; ZINC1674125; BBL028855; BDBM50242202; MFCD00665740; NSC-75194; SBB097925; STK802001; AKOS005622521; MCULE-1579680807; PS-6243; DS-013724; ST51035813; 3-(1-Methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)propanoic acid; 3-(3,4-Dihydro-4-methyl-3-oxoquinoxalin-2-yl)propanoic acid; 3-(1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)propionic acid AldrichCPR; 3-(1-methyl-2-oxo-1,2-dihydroquinoxalin-3-yl)propionic acid, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[20] | |||
| Compound Name |
N-((R)-4-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)pentyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164225; SCHEMBL8011164; BDBM50320742
Click to Show/Hide
|
||||
| Activity |
IC50 = 71300 nM
|
[19] | |||
| Compound Name |
Chembl4244181
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50463469
Click to Show/Hide
|
||||
| Activity |
IC50 = 71900 nM
|
[26] | |||
| Compound Name |
Chembl4245766
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50462241
Click to Show/Hide
|
||||
| Activity |
IC50 = 74400 nM
|
[27] | |||
| Compound Name |
Chembl4215552
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ZINC2489369; BDBM50455890; STK682580; AKOS001682365; MCULE-5137412756; (10-cyano-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]indolizin-3(4H)-yl)acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[20] | |||
| Compound Name |
Pimelic Diphenylamide 106
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TC-H 106; N1-(2-aminophenyl)-N7-(4-methylphenyl)-heptanediamide; N'-(2-aminophenyl)-N-(4-methylphenyl)heptanediamide; RGFA-8;TC-H 106;Histone Deacetylase Inhibitor VII; RGFA-8; SCHEMBL1065609; CHEMBL3940985; DTXSID10581754; EX-A916; TC-H106; BDBM207628; HMS3648I10; BCP16854; US9265734, RGFA8; 1900AH; MFCD17010287; s6738; ZINC34997445; AKOS024458065; CCG-208665; CS-5229; TC-H 106;Pimelic Diphenylamide 106; AK222718; AS-56015; HY-19348; FT-0700415; n1-(2-aminophenyl)-n7-p-tolylheptanediamide; EC-000.2470; Pimelic Diphenylamide 106, >=98% (HPLC); SR-01000946373; SR-01000946373-1; N-(4-Methylphenyl)-N'-(2-aminophenyl)heptanediamide; N1-(2-Aminophenyl)-N7-(4-methylphenyl)heptanediamide; Q27165947; N~1~-(2-Aminophenyl)-N~7~-(4-methylphenyl)heptanediamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[28] | |||
| Compound Name |
(R)-N-(2-Aminophenyl)-6-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)heptanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165293; SCHEMBL7996757; BDBM50320737
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[29] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800246; BDBM50348393
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[25] | |||
| Compound Name |
3-(6,7-Dimethoxy-4-oxoquinazolin-3(4H)-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4209794; 3-(6,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-3-yl)propanoic acid; CTK6J9964; ZINC8428176; BDBM50455897; STL520173; AKOS000118017; MCULE-5938433660; EN300-24257; AB00752194-01; Z199040706
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[20] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(6-phenylhexyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800385; BDBM50348387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
S-[5-[(3S,6R,9S,12R)-6-[2-(2-Acetylsulfanylethoxy)ethyl]-3-benzyl-2,5,8,11-tetraoxo-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]pentyl] ethanethioate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2158741; BDBM50394107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[(2S)-1-[[6-(2-Amino-4-fluoroanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4102988; BDBM50242039
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
2-{[2-(4-Tert-butylphenyl)-2-oxoethyl]sulfanyl}-6-methyl-3,4-dihydropyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800374; ZINC9143521; BDBM50348375; AKOS034466005; MCULE-3132766776; Z56923981
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[4-[2-(4-Methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800242; BDBM50348389
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[3-(sulfamoylamino)propyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3974665; BDBM50199124
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
2-N-(2-Aminophenyl)-5-N-[4-methyl-3-[(5-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]thiophene-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515109; BDBM50257117
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[4-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanylmethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800248; SCHEMBL17382802; BDBM50348395
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[(2S)-1-[[4-(Anilinocarbamoyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101933; BDBM50244810
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N1-(2-Aminophenyl)-N4-(3-(methyl(4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)terephthalamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL514511; SCHEMBL4087658; BDBM50256929
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
6-(Acetyl-hydroxy-amino)-hexanoic acid phenylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138293; TWZ-101; BDBM50138417
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
N1-(2-Aminophenyl)-N4-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)terephthalamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL475820; BDBM50256976
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[4-[2-[(4-Methyl-6-oxo-1H-pyridin-2-yl)oxy]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800247; BDBM50348394
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[(2S)-1-(1H-Indol-3-yl)-3-[4-[(E)-3-oxo-3-(2-propylhydrazinyl)prop-1-enyl]phenoxy]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4069908; BDBM50244785
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[6-oxo-6-(2-propylhydrazinyl)hexyl]amino]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070388; BDBM50244811
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(4-phenylbutyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800384; BDBM50348385
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N2-(2-Aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)thiophene-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL473825; BDBM50257030
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
1-((4-Hydroxy-6-methylpyrimidin-2-yl)thio)propan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800381; BDBM50348382; STL267143; AKOS008981021; AKOS016354209; MCULE-9373031239; 6-methyl-2-[(2-oxopropyl)sulfanyl]pyrimidin-4(3H)-one; 1-[(4-Oxo-6-methyl-3,4-dihydropyrimidine-2-yl)thio]-2-propanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[(2S)-1-[[4-[(Cyclopentylamino)carbamoyl]phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4077664; BDBM50244789
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-[4-[2-(3-Hydroxyphenyl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800245; BDBM50348392
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[4-[1-Hydroxy-2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]ethyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800249; BDBM50348396
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
(3S,6Z,9S,12R,16S)-6-Ethylidene-16-[(E)-4-methylsulfanylbut-1-enyl]-9-(methylsulfanylmethyl)-3,12-di(propan-2-yl)-1-oxa-4,7,10-triazacyclohexadecane-2,5,8,11,14-pentone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2093007
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
(4-(2-Aminophenylcarbamoyl)benzylamino)methyl nicotinate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL514671; BDBM50256975
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
3-(1-Methyl-1H-benzoimidazol-2-yl)-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(1-methylbenzimidazol-2-yl)propanoic acid; CHEMBL4204813; 3-(1-methyl-1H-benzimidazol-2-yl)propanoic acid; 3-(1-METHYL-1H-BENZOIMIDAZOL-2-YL)-PROPANOIC ACID; Oprea1_040214; SCHEMBL855333; CTK4F4391; DTXSID00389963; ZINC3120347; 8334AD; BBL028344; BDBM50455898; SBB079511; STK664119; AKOS000275789; MCULE-3207206517; DA-07716; ST077806; BB 0218171; FT-0764145; 3-(1-Methyl-1H-benzoimidazol-2-yl)propanoic acid; SR-01000325114; J-015673; SR-01000325114-1; 3-(1-methyl-1H-1,3-benzimidazol-2-yl)propanoic acid; 3-(1-methyl-1H-benzoimidazol-2-yl)-propionic acid, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[20] | |||
| Compound Name |
6-(3-Amino-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-7-yl)-N-hydroxyhex-5-ynamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2408821; BDBM50492628
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[4-[(pentylamino)carbamoyl]phenyl]methylamino]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094199; BDBM50244788
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]sulfanyl-4-methyl-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800377; SCHEMBL17382809; BDBM50348378
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[[[(4S,5S)-4,5-diphenyl-1,3-oxazolidin-2-ylidene]amino]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3605505; BDBM50113961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-[(2S)-1-[[4-(Butylaminocarbamoyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066668; BDBM50244819
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[7-oxo-7-(2-propylhydrazinyl)heptyl]amino]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4097567; BDBM50244820
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS000531589; CHEMBL1722433; SMR000136527; 2-[(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)thio]-N-(2-phenylethyl)acetamide; Oprea1_304490; cid_892234; BDBM96613; HMS2466G16; STK116346; ZINC18093765; AKOS000716785; AKOS001049225; MCULE-1856560484; SR-01000264561; SR-01000264561-1; Z56847664; 2-[(4-keto-6-methyl-1H-pyrimidin-2-yl)thio]-N-phenethyl-acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)sulfanyl]-N-(2-phenylethyl)acetamide; 2-[(6-methyl-4-oxo-1H-pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
8-(Acetyl-hydroxy-amino)-octanoic acid phenylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138626; TWZ-103; BDBM50138418
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
N'-Hydroxy-N-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl)hexanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2408819; SCHEMBL3790439; BDBM50492629
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-{4-[2-(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetyl]-phenyl}-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800244; Oprea1_373990; Oprea1_543124; ZINC841137; BDBM50348391; STK285981; AKOS001628005; MCULE-9514505423; N-(4-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}phenyl)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N2-(2-Aminophenyl)-N5-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)thiophene-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474208; BDBM50257116
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-[(2S)-1-[[6-(2-Amino-5-thiophen-2-ylanilino)-6-oxohexyl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065117; BDBM50242038
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[31] | |||
| Compound Name |
N2-(2-Aminophenyl)-N5-(3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)pyridine-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474863; BDBM50257078
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-Methyl-N-[4-[2-[(4-methyl-6-oxo-1H-pyrimidin-2-yl)sulfanyl]acetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800251; BDBM50348372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
(1R,14S,17R,23S)-23-Benzyl-4-oxa-7,8-dithia-15,21,24,26-tetrazatricyclo[12.11.2.017,21]heptacosane-16,22,25,27-tetrone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2158742; BDBM50394110
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[30] | |||
| Compound Name |
2-(Tert-butylcarbonylmethylthio)-4-hydroxy-6-methylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800382; Maybridge1_007088; CTK6C4190; HMS561K04; BDBM50348383; SBB099296; ZINC13468269; AKOS008981059; CCG-244729; MCULE-6331991984; 1-(4-hydroxy-6-methylpyrimidin-2-ylthio)-3,3-dimethylbutan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Nampt-IN-3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065412; BDBM50241438; HY-108701; CS-0030130
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
Hdac3-IN-T326
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622375; N-(2-Aminophenyl)-5-(1-(3-nitrophenethyl)-1H-1,2,3-triazol-4-yl)thiophene-2-carboxamide; BDBM50121211; T-326; N-(2-aminophenyl)-5-[1-[2-(3-nitrophenyl)ethyl]triazol-4-yl]thiophene-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
N-Hydroxy-5-(1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-7-yl)pent-4-ynamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2408690; SCHEMBL2924421; BDBM50492640
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[34] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[[[(2S)-3-(1H-indol-3-yl)-2-[(4-methoxybenzoyl)amino]propanoyl]amino]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4085511; BDBM50242050
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N2-(2-Aminophenyl)-N5-(4-methyl-3-(5-(pyridin-3-yl)thiazol-2-ylamino)phenyl)pyridine-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474046; BDBM50257115
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-(2-Aminophenyl)-4-[1-[2-(3-thienyl)ethyl]-1H-1,2,3-triazol-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
HDAC3-IN-T247; CHEMBL3622374; SCHEMBL18208054; BDBM50121210; MFCD29089340; T 247; T-247; N-(2-aminophenyl)-4-[1-(2-thiophen-3-ylethyl)triazol-4-yl]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[4-(propylaminocarbamoyl)phenyl]methylamino]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4086442; BDBM50244778
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
1-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3893970; BDBM50210264
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
Methyl 2-((4-hydroxy-6-methylpyrimidin-2-yl)thio)acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800380; methyl 2-(6-methyl-4-oxo-3-hydropyrimidin-2-ylthio)acetate; BDBM50348381; SBB062603; STK641838; STL281936; ZINC13739146; AKOS002262380; AKOS002308199; AKOS008981057; MCULE-6551097558; 2-Methoxycarbonylmethylenethio-6-methyluracil; ST50186106; methyl [(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]acetate; methyl [(4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetate; [(4-Oxo-3,4-dihydro-6-methylpyrimidine-2-yl)thio]acetic acid methyl ester; METHYL ((4-METHYL-6-OXO-1,6-DIHYDRO-2-PYRIMIDINYL)THIO)ACETATE; Methyl [(4-methyl-6-oxo-1,6-dihydro-2-pyrimidinyl)sulfanyl]acetate #
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
Methyl 7-anilino-7-oxoheptyl(hydroxy)carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138090; TWZ-106; BDBM50138411
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
N-[4-[2-(4-Methoxy-6-methylpyrimidin-2-yl)sulfanylacetyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1800243; BDBM50348390
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
N-[(2S)-3-(1H-Indol-3-yl)-1-oxo-1-[[8-oxo-8-(2-propylhydrazinyl)octyl]amino]propan-2-yl]-4-methoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4097113; BDBM50244812
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
4-[2-[[(16E)-14,19-Dioxa-5,7,27-triazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(24),2(27),3,5,8(26),9,11,16,21(25),22-decaen-11-yl]oxy]ethoxy]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3962918; BDBM50210255
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[21] | |||
| Compound Name |
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-[6-(3-hydroxy-2-oxopyridin-1-yl)hexyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912767; BDBM50199112
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N2-(2-Aminophenyl)-N5-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)pyridine-2,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515258; BDBM50257029
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexyl)butane-1-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165082; SCHEMBL8006554; BDBM50320745
Click to Show/Hide
|
||||
| Activity |
IC50 = 101000 nM
|
[19] | |||
| Compound Name |
3-[3-(2-Pyridin-2-yloxyethoxy)quinoxalin-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065929; BDBM50242193
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[23] | |||
| Compound Name |
2-(4-Hydroxybenzylidene)-1-benzofuran-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC657003; CHEMBL199974; (Z)-2-(4-hydroxybenzylidene)benzofuran-3(2H)-one; (2Z)-2-(4-hydroxybenzylidene)-1-benzofuran-3(2H)-one; SCHEMBL19462962; (2Z)-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one; BDBM50036880; ZINC12341651; AKOS001694044; NSC-657003; AN-308/15495080; 2-[(Z)-4-Hydroxybenzylidene]benzofuran-3(2H)-one; (2Z)-2-[(4-hydroxyphenyl)methylene]benzofuran-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 135900 nM
|
[39] | |||
| Compound Name |
3-[3-[(1-Methylimidazol-2-yl)methoxy]quinoxalin-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079348; BDBM50242192
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[23] | |||
| Compound Name |
3-(4-Benzyl-7-chloro-3-oxo-3,4-dihydroquinoxalin-2-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1527237; Enamine_005034; 3-(4-Benzyl-7-chloro-3-oxo-3,4-dihydro-quinoxalin-2-yl)-propionic acid; 3-(4-benzyl-7-chloro-3-oxoquinoxalin-2-yl)propanoic acid; MLS000775409; CTK7J3146; HMS1408E18; HMS2690J22; ZINC3269649; BDBM50455903; SBB076562; AKOS000117780; MCULE-4123426735; NE32155; IDI1_007621; SMR000368486; EN300-04184; J-510653; Z56887613; 3-[7-chloro-3-oxo-4-benzyl-4-hydroquinoxalin-2-yl]propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[20] | |||
| Compound Name |
N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexyl)trifluoromethanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164227; SCHEMBL7996743; BDBM50320744
Click to Show/Hide
|
||||
| Activity |
IC50 = 153000 nM
|
[19] | |||
| Compound Name |
Chembl4173739
Click to Show/Hide
|
Investigative | Compound Info | ||
| Activity |
IC50 ~ 160000 nM
|
[40] | |||
| Compound Name |
3-[3-[2-(3-Methylphenoxy)ethoxy]quinoxalin-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079465; BDBM50242194
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[23] | |||
| Compound Name |
3-(1,3-Benzothiazol-2-yl)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-(Benzo[d]thiazol-2-yl)propanoic acid; 2-benzothiazolepropanoic acid; 3-Benzothiazol-2-yl-propionic acid; CHEMBL4203995; 3-benzothiazol-2-ylpropanoic acid; carboxyethylbenzo-thiazoline; 2-Benzothiazolepropanoicacid; Acetic acidtert-butyl ester; Oprea1_387325; Oprea1_595955; Benzothiazole-2-propionic acid; IFLab1_004107; SCHEMBL1269672; CTK1A5518; DTXSID70354380; HMS1423K15; ZINC253409; ALBB-007815; ANW-54873; BBL013303; BDBM50455888; MFCD01764690; SBB010101; STK504822; AKOS000114797; FS-1813; MCULE-5471495347; DB-029314; FT-0740822; ST50015966; EN300-00819; KS-00002592; 3-benzothiazol-2-yl-propionic acid, AldrichCPR; W-8618; F0848-0307
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[20] | |||
| Compound Name |
(7,9-Dimethyl-4-oxopyrido[3',2':4,5]thieno[3,2-d]pyrimidin-3(4H)-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4211769; CTK7J5061; HMS1719I02; ZINC3888787; BDBM50455891; SBB078217; AKOS005137396; MCULE-5695520059; EN300-13238; AB00735677-01; SR-01000069218; SR-01000069218-1; Z89284935
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[20] | |||
| Compound Name |
N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)hexyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164226; SCHEMBL8006477; BDBM50320743
Click to Show/Hide
|
||||
| Activity |
IC50 = 191000 nM
|
[19] | |||
| Compound Name |
(1,4-Dioxo-3,4-dihydrophthalazin-2(1H)-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4207434; 2-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-2-yl)acetic acid; 2(1H)-Phthalazineacetic acid, 3,4-dihydro-1,4-dioxo-; 2-(1,4-dioxo-3H-phthalazin-2-yl)acetic Acid; SCHEMBL14884718; CTK1A7659; DTXSID10368320; ZINC3261550; BDBM50455889; AKOS000200892; MCULE-5577158828; NE44162; EN300-08230; SR-01000038864; SR-01000038864-1; Z56877833; 2-(1,4-Dioxo-3,4-dihydrophthalazin-2(1H)-yl)acetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[20] | |||
| Compound Name |
(6-Bromo-4-oxoquinazolin-3(4H)-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(6-bromo-4-oxo-3,4-dihydroquinazolin-3-yl)acetic acid; CHEMBL284979; (6-Bromo-4-oxo-4H-quinazolin-3-yl)-acetic acid; Oprea1_258289; CTK7J5055; TQP0818; ZINC949496; BBL026203; BDBM50455901; STL367239; AKOS000126811; MCULE-4751643198; ST50192416; T9560; 2-(6-bromo-4-oxoquinazolin-3-yl)acetic acid; EN300-40148; 2-(6-bromo-4-oxoquinazolin-3(4H)-yl)acetic acid; 2-(6-bromo-4-oxo-3-hydroquinazolin-3-yl)acetic acid; 6-Bromo-3,4-dihydro-4-oxoquinazoline-3-acetic acid; (6-bromo-4-oxoquinazolin-3(4H)-yl)acetic acid, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[20] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 23 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Romidepsin
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Chromadax; Istodax; Antibiotic FR 901228; FK 228; FK228; FR 901228; FR901228; HDInhib_000006; Chromadax (TN); FK-228; FK-901228; FR-901228; Istodax (TN); Romidepsin (USAN); Cyclo((2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl), cyclic (35)-disulfide; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide; (1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8.7.6)tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[30] | |||
| Compound Name |
Valproate
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
99-66-1; Dipropylacetic acid; Depakine; Depakene; 2-Propylvaleric acid; Ergenyl; Di-n-propylacetic acid; Mylproin; Pentanoic acid, 2-propyl-; 4-Heptanecarboxylic acid; Propylvaleric acid; n-Dipropylacetic acid; Myproic Acid; Di-n-propylessigsaure; n-DPA; Dipropylacetate; Convulex; Depakin; Vupral; Acido valproico; Acide valproique; Acidum valproicum; Stavzor; Avugane; Baceca; Kyselina 2-propylvalerova; 2-n-Propyl-n-valeric acid; Acetic acid, dipropyl-; Abbott 44090; Valproinsaeure; Savicol; Convulsofin; Deproic; VPA; Depakin chrono; Dipropyl Acetate; Med Valproic; Valproic acid USP; Valproic acid USP24; Acide valproique [INN-French]; Acido valproico [INN-Spanish]; Acidum valproicum [INN-Latin]; Alti-Valproic; Depakote (TM); Dom-Valproic; G2M-777; Kyselina 2-propylvalerova [Czech]; N-DPA; N-Dipropylacetic acid; Novo-Valproic; Nu-Valproic; PMS-Valproic Acid; Penta-Valproic; Valproic acid (USP); Di-n-propylessigsaeure; Di-n-propylessigsaure [German]; Valproic acid [USAN:INN:BAN]; Valproic Acid, SodiumSalt (2:1); 2 PP (base)
Click to Show/Hide
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||||
| Activity |
IC50 > 2000000 nM
|
[41] | |||
| Compound Name |
Phenylbutyrate
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Phase 2 | Compound Info | ||
| Synonyms |
Benzenebutyric acid; Phenyl butanoate; Phenyl butyrate; HDInhib_000004; Butanoic acid, phenyl ester; Butyric acid, phenyl ester; FR-2080; Gamma-Phenylbutyric acid; Omega-Phenylbutanoic acid; GAMMA-PHENYL-BUTYRIC ACID; Butyric acid, 4-phenyl-(8CI); 1-Phenylbutyric acid; 4-PHENYL-BUTANOIC ACID; 4-PHENYLBUTYRIC ACID; 4-Phenylbutanoic acid; 4-phenylbutans; 4-phenylbutyrate
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||||
| Activity |
IC50 = 240000 nM
|
[41] | |||
| Compound Name |
Butanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
butyric acid; butanoic acid; n-Butyric acid; 107-92-6; n-Butanoic acid; propylformic acid; ethylacetic acid; 1-propanecarboxylic acid; Butanic acid; butyrate; 1-Butyric acid; Buttersaeure; butanoate; Kyselina maselna; Butyric acid (natural); Propanecarboxylic acid; Buttersaeure [German]; 1-butanoic acid; FEMA Number 2221; Kyselina maselna [Czech]; FEMA No. 2221; CCRIS 6552; HSDB 940; butoic acid; Ethyacetic Acid; 2-butanoate; NSC 8415; UNII-40UIR9Q29H; UN2820; AI3-15306; EINECS 203-532-3; BRN 0906770; CH3-[CH2]2-COOH; 40UIR9Q29H
Click to Show/Hide
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||||
| Activity |
IC50 > 2000000 nM
|
[41] | |||
| Compound Name |
3-Methylquinoline-8-thiol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100994; 8-Quinolinethiol, 3-methyl-; 3-methyl-8-quinolinethiol; SCHEMBL3067414; BDBM50264503
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||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
5-Methylquinoline-8-thiol
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Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 5-methyl-; CHEMBL4084782; 5-methyl-8-quinolinethiol; SCHEMBL13977568; CTK1H9946; DTXSID70500764; BDBM50264484
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||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
4-Methylquinoline-8-thiol
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Investigative | Compound Info | ||
| Synonyms |
8-Quinolinethiol, 4-methyl-; CHEMBL4063134; 4-methyl-8-quinolinethiol; SCHEMBL15703126; CTK0B7293; DTXSID80492580; BDBM50264490
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||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
8-Mercaptoquinoline
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Investigative | Compound Info | ||
| Synonyms |
quinoline-8-thiol; 8-Quinolinethiol; SQT-8; 8-thioquinoline; [S]c1cccc2cccnc12; 8-Mercaptoquinoline (8TQ); NCIOpen2_001790; SCHEMBL536578; CHEMBL4076575; DTXSID70197678; BDBM224013; HMS1788G22; ZINC389710; NSC48888; NSC-48888; AKOS022191814; AKOS024342879; MCULE-9204136169; DB-070965; FT-0735097; MLS-0472512.0001; 8-Quinolinethiol;Quinoline-8-thiol;8-Thioquinoline; F9994-0398
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||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
8-[2-[[(5S,5As,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-5-yl]amino]phenoxy]-N-hydroxyoctanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2442693; BDBM50442735
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||||
| Activity |
IC50 = 217000 nM
|
[42] | |||
| Compound Name |
3-(4-Oxo-3,4-dihydroquinazolin-2-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
3-(4-oxo-1H-quinazolin-2-yl)propanoic acid; 3-(4-Oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid; 3,4-Dihydro-4-oxo-; CHEMBL1892587; NSC251919; Enamine_004755; 2-Quinazolinepropanoic acid, 1,4-dihydro-4-oxo-; MLS000775861; SCHEMBL2718160; SCHEMBL19953232; CTK1H2249; DTXSID00312256; HMS1407I03; HMS2754F07; ALBB-030898; ZINC1556709; BBL030181; BDBM50234922; MFCD03955531; STL374134; STL521303; AKOS000669520; AKOS005202394; AKOS028111280; MCULE-9759862525; NSC-251919; 2-(2-carboxyethyl)quinazolin-4(3h)-one; BS-14054; DA-42158; SMR000370984; 3-(4-hydroxyquinazolin-2-yl)propanoicacid; BB 0304036; FT-0667036; EN300-04546; SR-01000353582; 3-(4-HYDROXYQUINAZOLIN-2-YL)PROPANOIC ACID; SR-01000353582-1; 1,4-DIHYDRO-4-OXO-2-QUINAZOLINEPROPANOIC ACID; 3-(4-Oxo-1,4-dihydroquinazolin-2-yl)propanoic acid; Z56869288; 3-(4-oxo-3,4-dihydro-quinazolin-2-yl)-propionic acid, AldrichCPR
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||||
| Activity |
IC50 = 230000 nM
|
[20] | |||
| Compound Name |
3-(4-Oxo-1,2,3-benzotriazin-3(4H)-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
3-(4-oxo-1,2,3-benzotriazin-3-yl)propanoic acid; CHEMBL4211548; 3-(4-oxobenzo[d][1,2,3]triazin-3(4H)-yl)propanoic acid; 3-[4-oxo-1,2,3-benzotriazin-3(4H)-yl]propanoic acid; Oprea1_685647; SCHEMBL1845784; CTK1H4554; DTXSID80401172; 3-(4-OXO-1,2,3-BENZOTRIAZIN-3(4H)-YL)PROPANOICACID; ZINC225283; ALBB-015729; 4744AE; BDBM50455893; MFCD02926470; STK716433; AKOS001204334; MCULE-3909765899; AB0158269; FT-0684278; EN300-23489; L-4456; SR-01000388733; 1,2,3-Benzotriazine-3(4H)-propanoicacid, 4-oxo-; SR-01000388733-1; 1,2,3-Benzotriazine-3(4H)-propanoic acid, 4-oxo-; F0914-0125; 3-(4-oxo-1,2,3-benzotriazin-3(4H)-yl)propanoic acid, AldrichCPR
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||||
| Activity |
IC50 = 240000 nM
|
[20] | |||
| Compound Name |
3-{3-[(Pyridin-2-Yl)methoxy]quinoxalin-2-Yl}propanoic Acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4095967; BDBM50242198; B8P
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||||
| Activity |
IC50 = 270000 nM
|
[23] | |||
| Compound Name |
N-((R)-5-((1R,3As,7aR,E)-4-(2-((3R,5R)-3,5-Dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexyl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165164; SCHEMBL8009057; BDBM50320746
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||||
| Activity |
IC50 = 293000 nM
|
[19] | |||
| Compound Name |
(4-Oxo-4H-quinazolin-3-yl)-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
(4-oxoquinazolin-3(4H)-yl)acetic acid; 2-(4-Oxoquinazolin-3(4H)-yl)acetic acid; 2-(4-oxoquinazolin-3-yl)acetic acid; CHEMBL1471153; 2-(4-oxo-3,4-dihydroquinazolin-3-yl)acetic acid; 3(4H)-Quinazolineacetic acid, 4-oxo-; (4-oxo-3(4H)-quinazolinyl)acetic acid; (4-oxo-4h-quinazolin-3-yl)acetic acid; SMR000124647; 2-(4-oxo-3-hydroquinazolin-3-yl)acetic acid; Cambridge id 6340677; Oprea1_877489; MLS000067222; MLS004820191; SCHEMBL13799935; DTXSID10352567; HMS1693A21; HMS2473H12; ZINC141049; ALBB-012760; 4-Oxoquinazoline-3(4H)-acetic acid; 7266AA; ANW-71308; BBL000456; BDBM50455885; MFCD02332713; SBB018911; STK299906; AKOS000104308; HY-W030545; MCULE-1898391590; SDCCGMLS-0065106.P001; ST096054; (4-Oxo-3-quinazolinyl)acetic acid, 97%; 2-[4-oxo-3(4H)-quinazolinyl]acetic acid; AB0089107; DB-031043; BB 0218508; CS-0074569; FT-0677233; EN300-05236; W-9406; 663O537; SR-01000459432; SR-01000459432-1; BRD-K13123739-001-08-1; Z56895681; F0911-6393
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||||
| Activity |
IC50 = 320000 nM
|
[20] | |||
| Compound Name |
(R)-N-(2-Aminophenyl)-5-((1R,3aS,7aR,E)-4-(2-((3R,5R)-3,5-dihydroxycyclohexylidene)ethylidene)-7a-methyl-octahydro-1H-inden-1-yl)hexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165292; SCHEMBL7997195; BDBM50320741
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||||
| Activity |
IC50 = 330000 nM
|
[19] | |||
| Compound Name |
3-(6-Oxidanylidene-3-Pyridin-3-Yl-Pyridazin-1-Yl)propanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084541; 3-(6-oxo-3-pyridin-3-ylpyridazin-1(6H)-yl)propanoic acid; BDBM50242195; ZINC61957849; AKOS015956060; Q27456553
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||||
| Activity |
IC50 = 350000 nM
|
[23] | |||
| Compound Name |
(3S,6S,9S,12R)-3,6-Dimethyl-9-[6-(oxiran-2-yl)-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.3.0]pentadecane-2,5,8,11-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL144205; BDBM50134803
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||||
| Activity |
EC50 = 360000 nM
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[43] | |||
| Compound Name |
2-(Benzo[d]thiazol-2-yl)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
2-Benzothiazoleacetic acid; 2-(1,3-benzothiazol-2-yl)acetic acid; (Benzothiazol-2-yl)acetic acid; (1,3-Benzothiazol-2-yl)acetic acid; 1,3-benzothiazol-2-ylacetic acid; CHEMBL4212057; 2-(BENZOTHIAZOL-2-YL)ACETIC ACID; (Benzothiazol-2-yl)aceticacid; 2-benzothiazol-2-ylacetic Acid; Oprea1_311322; (2-benzothiazolyl)acetic acid; SCHEMBL1612659; CTK1A6267; DTXSID50406917; HMS1783B04; ACT03782; KS-000029WY; ZINC4204714; ANW-60839; BDBM50455894; MFCD00483536; SBB018913; AKOS008967709; AB06316; MCULE-7813389385; PS-3305; SC-48720; AB0038029; DB-013116; A5468; FT-0652532; Y5375; 182B454; J-506220
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||||
| Activity |
IC50 = 390000 nM
|
[20] | |||
| Compound Name |
(3S,6S,9S,12R)-3,6-Dibenzyl-9-[6-(oxiran-2-yl)-6-oxohexyl]-1,4,7,10-tetrazabicyclo[10.4.0]hexadecane-2,5,8,11-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL274445; BDBM50134805
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||||
| Activity |
EC50 = 524000 nM
|
[43] | |||
| Compound Name |
Chembl4214608
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455895; ZINC67878561; MCULE-5266275146; 3-{1-[5-(aminocarbonyl)-3-thienyl]-1H-benzimidazol-2-yl}propanoic acid
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||||
| Activity |
IC50 = 640000 nM
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[20] | |||
| Compound Name |
(S)-N-(1-(5-(2-Methoxyquinolin-3-yl)-1H-imidazol-2-yl)-7-oxooctyl)-1-methylazetidine-3-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448576; CHEMBL466644; SCHEMBL2073575; BDBM50258579; ZINC35803333; N-[(1S)-1-[5-(2-methoxyquinolin-3-yl)-1H-imidazol-2-yl]-7-oxononyl]-1-methylazetidine-3-carboxamide
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| Activity |
IC50 = 680000 nM
|
[44] | |||
| Compound Name |
2-Quinolinepropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
3-(quinolin-2-yl)propanoic acid; 3-quinolin-2-ylpropanoic acid; CHEMBL4218506; 2-Quinolinepropionic acid; quinolinepropanoic acid; 2-Quinolinepropanoicacid; SCHEMBL547194; CTK1C2792; DTXSID80295033; HMS1781B16; NSC99366; ZINC1654190; 3-QUINOLIN-2-YLPROPANOICACID; BDBM50455899; MFCD06655354; NSC-99366; AKOS008987597; MCULE-7965912465; NE26384; BS-13993; 3-quinolin-2-ylpropanoic acid, AldrichCPR; EN300-12576; Z85922627
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||||
| Activity |
IC50 > 720000 nM
|
[20] | |||
| Compound Name |
Chembl4249195
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Investigative | Compound Info | ||
| Synonyms |
BDBM50462240
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||||
| Activity |
IC50 > 10000000 nM
|
[27] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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