Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T70176 | Target Info | |||
| Target Name | Cyclin-dependent kinase 2 (CDK2) | ||||
| Synonyms |
Sin3 associated polypeptide; SIN3-associated protein; P33 protein kinase; Cell division protein kinase 2; CDKN2
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| Target Type | Clinical trial Target | ||||
| Gene Name | CDK2 | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 136 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Erlotinib
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Approved | Compound Info | ||
| Synonyms |
Erlotinin; Tarceva; Erlotinib Base; OSI 744; R 1415; CP 358,774; CP-358774; Erlotinib(Tarceva); Tarceva (TN); CP-358,774; Erlotinib, OS-774; N-(3-ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine; N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine; N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-Quinazolinamine; [6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE; [6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine; 4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; 4-[(3-ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
LEE011
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Phase 3 | Compound Info | ||
| Synonyms |
Ribociclib; LEE011; 1211441-98-3; LEE-011; Kisqali; Ribociclib(LEE011); UNII-TK8ERE8P56; LEE 011; 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; TK8ERE8P56; Ribociclib (LEE011); AK174906; 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo [2,3-d]pyrimidine-6-carboxylic acid dimethylamide; Ribociclib [USAN:INN]; LEE011A; Tube013
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| Activity |
IC50 = 76000 nM
|
[2] | |||
| Compound Name |
AR-A014418
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Patented | Compound Info | ||
| Synonyms |
487021-52-3; GSK-3beta Inhibitor VIII; 1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea; 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea; A Inhibitor VIII; N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA; UNII-87KSH90Q6D; AR-AO 14418; SN 4521; AR-A 014418; CHEMBL259850; 87KSH90Q6D; N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea; AK175829; C12H12N4O4S; N-(4-Methoxybenzyl)-N& -(5-nitro-1,3-thiazol-2-yl)urea; AR 014418; GSK 3be
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
NSC-73306
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Investigative | Compound Info | ||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
PMID16451062C46
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Investigative | Compound Info | ||
| Synonyms |
GTPL8355; GSK-623906A; BDBM50181532
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| Activity |
IC50 = 62000 nM
|
[5] | |||
| Compound Name |
3-Naphthalen-2-yl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-5-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2442310; SCHEMBL4595641; BDBM50442672; SR-01000383791; SR-01000383791-1
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(4Z)-4-({[4-(Piperidin-1-ylmethyl)phenyl]amino}methylene)-6-thien-3-ylisoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL488349; SCHEMBL13343914; BDBM50271199
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-4-({[4-(3,4-Dimethylpiperazin-1-yl)phenyl]amino}methylene)-6-iodoisoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL476907; SCHEMBL3574703; BDBM50270520; (4Z)-4-[[4-(3,4-dimethylpiperazin-1-yl)anilino]methylidene]-6-iodoisoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(4-Fluorophenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL486712; SCHEMBL3561217; BDBM50271201; (4Z)-6-(4-fluorophenyl)-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL357756; CHEMBL3822972; BDBM206104; DB-085143; US9255110, 17
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| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
14,16-Dihydroxy-3,5-dioxa-10-azapentacyclo[9.7.1.02,6.08,19.013,18]nonadeca-1(18),2(6),7,11(19),12,14,16-heptaen-9-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL599312; BDBM50306876; 8,10-Dihydroxy-6H-benzo[f][1,3]dioxolo[4'',5'':4,5]benzo[1,2,3-cd]indol-5-one
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[5-(4-methylpiperazin-1-yl)pyrazin-2-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL521459; BDBM50270645
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-Hydroxy-4-[[4-(piperidin-1-ylmethyl)phenyl]iminomethyl]-6-pyrrol-1-yl-2H-isoquinolin-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL529661; SCHEMBL13343891; BDBM50271115
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(4Z)-6-Nitro-4-{[(4-piperidin-1-ylmethyl)phenyl]amino}methyleneisoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL520864; SCHEMBL3566862; BDBM50271088
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(4Z)-6-(4-Methoxyphenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)-isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL483530; SCHEMBL3565038; SCHEMBL3565041; BDBM50271267; (4Z)-6-(4-methoxyphenyl)-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Corytuberine
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Investigative | Compound Info | ||
| Synonyms |
(S)-corytuberine; UNII-4YJ94A3D8W; 4YJ94A3D8W; CHEMBL227965; (+)-CORYTUBERINE; SCHEMBL680034; DTXSID40199649; HY-N2570; ZINC2554931; BDBM50197838; MFCD06809887; AKOS000276779; CS-0022907; C17591; Q27155145
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
(4Z)-6-Iodo-4-[({4-[(2S,5R)-2,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL477077; SCHEMBL3563275; BDBM50270521; (4Z)-6-iodo-4-[[4-[(2S,5R)-2,4,5-trimethylpiperazin-1-yl]anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-Phenyl-4-({[4-piperidin-1-ylmethyl]phenyl}amino)-methylene)}isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL487521; SCHEMBL13343909; BDBM50271146
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(3r)-1-{2-[4-(4-Acetylphenyl)piperazin-1-Yl]-2-Oxoethyl}-N-(3-Chloro-4-Hydroxyphenyl)pyrrolidine-3-Carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3356117; SCHEMBL7878839; BDBM50030881; Q27453793
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
Salutaridine
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Investigative | Compound Info | ||
| Synonyms |
Sinoacutine; UNII-7X10PRH74D; 7X10PRH74D; (-)-Sinoacutine; (-)-salutaridine; 4-Hydroxy-3,6-dimethoxy-17-methyl-5,6,8,14-tetradehydromorphinan-7-one; 5,6,8,14-Tetradehydro-4-hydroxy-3,6-dimethoxy-17-methyl-morphinan-7-one; (+)-salutaridine; SCHEMBL563455; CHEMBL404097; HSDB 8325; DTXSID60941041; BDBM50378615; Morphinan-7-one, 5,6,8,14-tetradehydro-4-hydroxy-3,6-dimethoxy-17-methyl-; C05179; Q7406319
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
6-Bromo-4-[(4-piperidin-1-ylmethyl-phenylamino)methylene]-4H-isoquinoline-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL407095; isoquinolinedione, 2; SCHEMBL3566851; SCHEMBL3566854; BDBM28047; 6-bromo-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
WYE-354; WYE 354; pyrazolo pyrimidine, 19; cc-506; MLS006011008; SCHEMBL300431; CHEMBL561708; GTPL9361; WYE354; BDBM35587; DTXSID00657912; C24H29N7O5; HMS3654N09; BCP02898; ZINC43013490; CCG-264882; CS-0183; SB19260; NCGC00242484-01; NCGC00242484-02; NCGC00242484-09; AC-28454; AS-55957; HY-12034; SMR004702806; BCP0726000260; DB-059456; FT-0675866; S1266; SW219671-1; X7422; W-5702; J-001552; J-514253; BRD-K77008974-001-01-6; Q27166532; mTOR Kinase Inhibitor II, WYE-354 - CAS 1062169-56-5
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| Activity |
IC50 ~ 50000 nM
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[11] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949788; SCHEMBL12134179; BDBM50364832; CH-4932748
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| Activity |
IC50 ~ 50000 nM
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[12] | |||
| Compound Name |
(4Z)-6-(4-Chlorophenyl)-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL483514; SCHEMBL3564297; BDBM50271234; (4Z)-6-(4-chlorophenyl)-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
Isocorydine
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Investigative | Compound Info | ||
| Synonyms |
(+)-Isocorydine; (+)-isocorynoline; Artabotrin; Luteanin; Uzokoridin; L-(+)-Isocorydine; Isocorydine (+); S-ISOCORYDINE (+); Lindcarpine, N,O-dimethyl-; Artabotrine; Luteanine; d-Isocorydine; (S)-isocorydine; UNII-3B5E87JEOX; S-(+)-Isocorydine; Aporphin-11-ol, 1,2,10-trimethoxy-; 3B5E87JEOX; Isocorydine hydrochloride; CHEMBL489525; Luteanine (VAN); SR-01000841246; NSC 32979; NSC 645316; BRN 0094792; S-Artabotrine; NSC645316; S-Luteanine; Prestwick_281; Spectrum_001207; SpecPlus_000517; (S)-(+)-Isocorydine; Prestwick0_000597; Prestwick1_000597; Prestwick2_000597; Prestwick3_000597; Spectrum2_000566; Spectrum3_000717; Spectrum4_001699; Spectrum5_000378; BSPBio_000474; BSPBio_002533; KBioGR_001998; KBioSS_001687; 5-21-06-00132 (Beilstein Handbook Reference); MLS002153898; DivK1c_006613; SCHEMBL679908; SPECTRUM1500860; SPBio_000352; SPBio_002693; 6a-alpha-APORPHIN-11-OL, 1,2,10-TRIMETHOXY-; BPBio1_000522; KBio1_001557; KBio2_001687; KBio2_004255; KBio2_006823; KBio3_001753; ZINC56792; DTXSID50929035; HMS1569H16; HMS1921K18; HMS2096H16; HMS2230M17; HMS3886N20; HY-N2591; TNP00260; 8152AH; BDBM50250273; CCG-38732; MFCD00075905; s9258; STL565301; AKOS015896784; SDCCGMLS-0066694.P001; NCGC00016453-01; NCGC00016453-02; NCGC00016453-03; NCGC00016453-04; NCGC00016453-05; NCGC00142508-01; NCGC00178615-01; NCGC00178615-02; SMR001233247; ST057169; CS-0022943; 1,2,10-Trimethoxy-6a-alpha-Aporphin-11-ol; C09549; I-7850; 475I672; SR-01000841246-3; SR-01000841246-4; 6aalpha-Aporphin-11-ol, 1,2,10-trimethoxy- (8CI); BRD-K37049577-001-05-1; BRD-K37049577-001-08-5; Q27106973
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095626; SCHEMBL3984085; BDBM50316252; methyl 4-[6-(4-aminophenyl)-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carboxylate
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| Activity |
IC50 ~ 50000 nM
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[13] | |||
| Compound Name |
[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3086065; SCHEMBL959662; BDBM50443366
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| Activity |
IC50 ~ 50000 nM
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[14] | |||
| Compound Name |
(4Z)-6-(4-Hydroxyphenyl)-4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL482918; SCHEMBL13343915; BDBM50271236
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(4Z)-4-[[4-(Piperidin-1-ylmethyl)anilino]methylidene]-6-thiophen-3-ylisoquinoline-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL486711; SCHEMBL3565592; BDBM50271200
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(4Z)-6-(4-Phenoxyphenyl)-(4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL489655; SCHEMBL13343912; BDBM50271268
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
N-[(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-1,3-dioxo-1,2,3,4-tetrahydroisoquinolin-6-yl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL487731; SCHEMBL3567242; BDBM50270776; N-[(4Z)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]-1,3-dioxoisoquinolin-6-yl]acetamide
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL487328; SCHEMBL3563277; BDBM50270881; (4Z)-6-(furan-3-yl)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(R)-3-(6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL602471; BDBM50306677
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| Activity |
IC50 ~ 50000 nM
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[15] | |||
| Compound Name |
6-Bromo-4-{[4-(4-methyl-piperazin-1-yl)-phenylamino]-methylene}-4H-isoquinoline-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL486286; (4Z)-6-bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione; (4Z)-6-bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl}amino}methylene)isoquinoline-1,3(2H,4H)-dione; SCHEMBL3562396; BDBM50270734; (4Z)-6-bromo-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]isoquinoline-1,3-dione; 6-bromo-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]isoquinoline-1,3-dione; (4Z)-6-Bromo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1949789; SCHEMBL12134185; BDBM50364833; CH-4932750
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
Stephanine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL601020; DTXSID90965972; ZINC2561271; BDBM50306887; W1147; 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7,7a,8-tetrahydro-9-methoxy-7-methyl-, (R)-; 9-Methoxy-7-methyl-6,7,7a,8-tetrahydro-2H,5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
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| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
(4Z)-6-(2-Furyl)-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL487327; SCHEMBL3569884; BDBM50270880; 6-(furan-2-yl)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]isoquinoline-1,3-dione
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL600795; BDBM50306683
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| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
(4Z)-6-Iodo-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL488955; SCHEMBL3570748; BDBM50270773; (4Z)-6-iodo-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
3-(5-Fluoro-6-Iodo-1-Methyl-1h-Indol-3-Yl)-4-(7-Methoxy-1-Benzofuran-3-Yl)-1h-Pyrrole-2,5-Dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523435; SCHEMBL3142971; BDBM50267521; Q27466736; 3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione; 3-(5-fluoro-6-iodo-1-methylindol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)pyrrole-2,5-dione; 3-(5-Fluoro-6-iodo-1-methyl-1H-indol-3-yl )-4-(7-methoxy benzofuran-3-yl)-pyrrole-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[16] | |||
| Compound Name |
5-[6-(5-Difluoromethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-2,4-difluoro-N-methoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL194498; SCHEMBL5605870; BDBM50168403
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL530335; SCHEMBL3562987; BDBM50270642
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-thien-3-ylisoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL486091; SCHEMBL3569974; BDBM50271036; (4Z)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]-6-thiophen-3-ylisoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515949; SCHEMBL3571007; BDBM50270522
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
4-{[(4-Hydroxy-5-methoxy-pyrimidin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477862; SCHEMBL3575366; SCHEMBL3575370; SCHEMBL13344243; BDBM50267401; 6-iodo-4-[[(5-methoxy-6-oxo-1H-pyrimidin-2-yl)methylamino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-N-methoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365318; BDBM50168387
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
Canadine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tetrahydroberberine; Xanthopuccine; Canadin; dl-Canadine; Berberine, tetrahydro-; NSC 94918; (d,l)-Tetrahydroberberine; NSC 36351; CHEMBL275097; 9,10-Dimethoxy-2,3-(methylenedioxy)berbine; Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-; NSC36351; dl-Tetrahydroberberine; DSSTox_CID_2724; Canadine dl-form; DSSTox_RID_76701; DSSTox_GSID_22724; Tetrahydroberberine,THB; EINECS 208-338-2; tetrahydro-; NCGC00016486-01; Prestwick_186; (+-)-Canadine; (.+-.)-Canadine; (+-)-Tetrahydroberberin; (.+/-.)-Canadine; Prestwick0_000672; Prestwick1_000672; Prestwick2_000672; Prestwick3_000672; CANADINE (DL-); Canadine, (.+-.)-; TimTec1_005946; Oprea1_387569; Oprea1_388593; (.+-.)-Tetrahydroberberine; BSPBio_000763; MLS001202314; SCHEMBL232164; SPBio_002684; BPBio1_000841; DTXSID5022724; HMS1550O06; HMS1570G05; HMS2097G05; HMS2852B23; HMS3358B11; HMS3886O13; HY-N0925; NSC94918; Tox21_110451; 8070AH; BBL028121; BDBM50203122; MFCD00067284; NSC-36351; NSC-94918; s5153; STK722197; AKOS000277103; AKOS021856290; Tox21_110451_1; CCG-202815; EBD2205518; MCULE-3875114127; NCGC00173359-04; NCGC00173359-06; NCGC00173359-08; NCI60_003328; NCI60_042115; SMR000393885; ST047929; VS-08674; Berbine,10-dimethoxy-2,3-(methylenedioxy)-; FT-0659151; FT-0664216; 522C974; BRD-A69950438-001-04-5; BRD-A69950438-001-11-0; Q27109653; Berbine,10-dimethoxy-2,3-(methylenedioxy)-, (.+-.)-; 6H-Benzo[g]-1,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-; 6H-Benzo[g]-1,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10,dimethoxy-, (.+-.)-
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
4-[[6-(Ethylamino)-2-[[1-(phenylmethyl)-5-indolyl]amino]-4-pyrimidinyl]amino]-1-cyclohexanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cdk4/6 Inhibitor IV; CHEMBL2028998; CHEMBL1242367; CGP82996; Cdk4/6InhibitorIV; SCHEMBL14040726; SCHEMBL14334441; SCHEMBL14334442; HMS2043N19; BDBM50378824; BDBM50503352; CINK4, >=95% (HPLC); AKOS016358850; ZINC101499579; CGP-082996; NCGC00346952-01; Q27163298
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[19] | |||
| Compound Name |
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-(phenylethynyl)-isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487737; SCHEMBL3563019; BDBM50271039; (4Z)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]-6-(2-phenylethynyl)isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
4-[(3-Hydroxy-4-pyridin-4-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477860; SCHEMBL3568412; BDBM50267399
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
(4Z)-6-(3-Methoxyphenyl)-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL482919; SCHEMBL3568154; BDBM50271237
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[6-(4-methylpiperazin-1-yl)pyridin-3-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL486497; SCHEMBL3565602; BDBM50270579
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-Piperidin-1-yl-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488549; SCHEMBL3566787; BDBM50271117; (4Z)-6-piperidin-1-yl-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
[4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid tetrahydro-furan-2-ylmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL370266; BDBM50168392
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(4Z)-6-Nitro-4-({[4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488342; SCHEMBL3573357; SCHEMBL3573360; BDBM50270736; (4Z)-6-Nitro-4-({[4-(4-methylpiperazin-1-yl)phenyl}amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-4-({[3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-methylene)-6-(3-furyl)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488562; SCHEMBL3563106; BDBM50270643
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(3-Furyl)-4-({[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL483081; SCHEMBL3572258; BDBM50270644
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-Piperidin-1-yl-4-({[4-(methylpiperazin-1-yl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL485892; SCHEMBL13343924; BDBM50270878
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(Furan-3-yl)-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylidene)-1,2,3,4-tetrahydroisoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL260864; isoquinolinedione, 32; SCHEMBL13343908; BDBM28077
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1095627; SCHEMBL3991434; BDBM50316253
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
Corydine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(+)-Corydine; UNII-1O1D15OP5R; Glaucentrin; Glaucentrine; d-Corydine; (S)-(+)-Corydine; 1O1D15OP5R; CHEMBL489524; O(sup 11)-Methylcorytuberine; BRN 0095568; 5-21-06-00134 (Beilstein Handbook Reference); SCHEMBL680230; 6a-alpha-APORPHIN-1-OL, 2,10,11-TRIMETHOXY-; DTXSID00963883; 2,10,11-Trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-1-ol; HY-N2571; ZINC1651264; BDBM50250271; MFCD00076020; AKOS000277266; MCULE-9044290951; CS-0022908; Q27252668; UNII-24S71U195F component IDQUPXZJURZAGF-ZDUSSCGKSA-N
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
3-Hydroxy-6-(4-methylpiperazin-1-yl)-4-[[4-(piperidin-1-ylmethyl)phenyl]iminomethyl]-2H-isoquinolin-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL485878; SCHEMBL13343928; BDBM50271145
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Crebanine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Crebanin; 8,9-Dimethoxy-1,2-(methylenedioxy)aporphine; CHEMBL604339; CTK4F5040; DTXSID80947989; AKOS032948508; 1,2-methylenedioxy-8,9-dimethoxyaporphine; FT-0776744; Aporphine, 8,9-dimethoxy-1,2-(methylenedioxy)- (8CI)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
2-(6-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL602472; BDBM50306684; CH-5234152
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[15] | |||
| Compound Name |
(4Z)-6-Anilino-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL409861; isoquinolinedione, 5; SCHEMBL3567788; BDBM28050; (4Z)-6-anilino-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1089082; SCHEMBL4656083; BDBM50314051; N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[20] | |||
| Compound Name |
Roemerine HBr
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL602275
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
6-Iodo-4-{[4-(5-methyl-2,5-diaza-bicyclo[2.2.1]hept-2-yl)-phenylamino]-methylene}-4H-isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488128; SCHEMBL3565512; BDBM50270735
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-Morpholin-4-yl-4-({[4-(piperidin-1-ylmethyl)phenyl]-amino}methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL485877; SCHEMBL3568897; BDBM50271144; (4Z)-6-morpholin-4-yl-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
[4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid 3-methanesulfonyl-propyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195218; SCHEMBL5605704; BDBM50168389
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-(1H-pyrrol-1-yl)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487730; SCHEMBL3568645; BDBM50270775; (4Z)-4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]-6-pyrrol-1-ylisoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-4-({[4-(3,5-Dimethylpiperazin-1-yl)phenyl]amino}methylene)-6-iodoisoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL483728; SCHEMBL13344011; BDBM50271270
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-Chloro-4-({[4-(piperidin-1-ylmethyl)phenyl]amino}-methylene)isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL486301; SCHEMBL3566999; BDBM50271087; (4Z)-6-chloro-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-4-({[4-(4-Methylpiperazin-1-yl)phenyl]amino}methylene)-6-phenylisoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487326; SCHEMBL3574781; BDBM50270879; 4-[[4-(4-methylpiperazin-1-yl)anilino]methylidene]-6-phenylisoquinoline-1,3-dione
Click to Show/Hide
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||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
6-Methoxy-4-[(4-piperidin-1-ylmethyl-phenylamino)-methylene]-4H-isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL484288; SCHEMBL3577953; SCHEMBL3577954; SCHEMBL13343906; BDBM50271086; 6-methoxy-4-[[4-(piperidin-1-ylmethyl)anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Dicentrine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
d-Dicentrine; L-DICENTRINE; Eximine; O,N-Dimethyllitseferine; UNII-J2ZGT5M0N7; Dicentrine-(+); J2ZGT5M0N7; CHEMBL464748; NSC406035; Dicentrin; CCRIS 3806; NSC 406035; BRN 0095476; 1,2-Methylenedioxy-9,10-dimethoxyaporphine; 9,10-Dimethoxy-1,2-(methylenedioxy)aporphine; (S)-form;(+)-Dicentrine; 4-27-00-06486 (Beilstein Handbook Reference); 9,2-(methylenedioxy)aporphine; SCHEMBL6369440; ZINC5319; DTXSID10199651; 6a-alpha-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)-; HY-N6969; 8161AH; BDBM50306885; AKOS037514612; NSC-406035; CS-0026026; C17426; Q-100578; Q15410930; 6a.alpha.-Aporphine,10-dimethoxy-1,2-(methylenedioxy)-; 9,10-Dimethoxy-1,2-(methylenedioxy)-6a.alpha.-aporphine; UNII-J3IJ5DN3JE component YJWBWQWUHVXPNC-AWEZNQCLSA-N; 6aalpha-Aporphine, 9,10-dimethoxy-1,2-(methylenedioxy)- (8CI)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
4-[3-[[4-(Dimethylamino)benzoyl]amino]-2-fluorophenyl]-7-(4-methylpiperazine-1-carbonyl)-9H-carbazole-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622193; BDBM50123457
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[21] | |||
| Compound Name |
5-{6-[5-(Difluoro-methanesulfonyl-methyl)-[1,3,4]oxadiazol-2-yl]-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino}-2,4-difluoro-N-methoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195903; SCHEMBL5605694; BDBM50168402
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(4Z)-6-Iodo-4-[({4-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]phenyl}amino)methylene]-isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL477073; SCHEMBL3573259; BDBM50270519; (4Z)-6-iodo-4-[[4-[(3S,5R)-3,4,5-trimethylpiperazin-1-yl]anilino]methylidene]isoquinoline-1,3-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(4Z)-6-(3-Hydroxyphenyl)-4-({[4-piperidin-1-ylmethyl]phenyl}-amino)methylene)}isoquinoline-1,3(2H,4H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL520458; SCHEMBL13343910; BDBM50271235
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
4-[(3-Hydroxy-4-pyridin-2-yl-benzylamino)-methylene]-6-iodo-4H-isoquinoline-1,3-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451298; SCHEMBL3570112; BDBM50267351
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
Sinomenine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cucoline; Kukoline; Coculine; Sabianine A; CCRIS 1550; UNII-63LT81K70N; CHEMBL248095; 63LT81K70N; SR-05000002170; EINECS 204-094-6; BRN 0095280; Sinomenine,(S); Sinomenine (Cucoline); Spectrum2_001242; Spectrum3_001134; Spectrum4_001981; Spectrum5_001621; UPCMLD-DP085; BSPBio_002627; KBioGR_002508; 5-21-13-00516 (Beilstein Handbook Reference); SCHEMBL363812; SPECTRUM1505253; SPBio_001144; 4-Hydroxy-3,7-dimethoxy-17-methyl-7,8-didehydromorphinan-6-one; UPCMLD-DP085:001; BCBcMAP01_000195; KBio3_002127; DTXSID00871595; BDBM224031; ALBB-020908; BCP20032; ZINC1280591; BDBM50241298; CCG-39100; s2359; AKOS000265568; AKOS015960539; AKOS016023715; AC-8025; SMP1_000273; NCGC00161641-01; NCGC00161641-02; NCGC00161641-04; NCGC00161641-05; HY-15122; SC-13744; CS-0003778; SW219295-1; C09643; 115S537; Sinomenine, 0.3 mol chloroform of crystallization; Q7524904; SR-05000002170-2; SR-05000002170-3; BRD-K83459933-001-02-1; 3-(4-Fluorophenyl)-3-(toluene-4-sulfonylamino)-propionicacid; 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
4-Nitro-2-{[4-(methylsulfanyl)benzylidene]amino}phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616869; AN-329/11481609; ARONIS021476; KS-00004CY8; BDBM50121656; STK008355; ZINC19860498; AKOS000487887; ZINC252462190; MCULE-3232268670; ST45035154; 2-{[4-(methylsulfanyl)benzylidene]amino}-4-nitrophenol; 2-[(1E)-2-(4-methylthiophenyl)-1-azavinyl]-4-nitrophenol; 2-({(E)-[4-(methylsulfanyl)phenyl]methylidene}amino)-4-nitrophenol
Click to Show/Hide
|
||||
| Activity |
IC50 = 52120 nM
|
[22] | |||
| Compound Name |
CID 56673689
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809197; SCHEMBL3316724; BDBM50349776
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[23] | |||
| Compound Name |
AZ-Dyrk1B-33
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3421980; 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine; AZ Dyrk1B 33; BDBM50081189; AKOS030210999; Cc1nccc(n1)c2cn(Cc3ccccc3)c4cnccc24; HY-117391; CS-0065849
Click to Show/Hide
|
||||
| Activity |
IC50 = 56703 nM
|
[24] | |||
| Compound Name |
Benzamide, 4-[[4-amino-6-(cyclohexylmethoxy)-2-pyrimidinyl]amino]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-((4-Amino-6-(cyclohexylmethoxy)pyrimidin-2-yl)amino)benzamide; 4-{[4-amino-6-(cyclohexylmethoxy)pyrimidin-2-yl]amino}benzamide; 2-arylamino-pyrimidine deriv. 8a; BDBM5589; CHEMBL319709; SCHEMBL12589617; CTK2E7584; DTXSID90416196; 4-[[6-(Cyclohexylmethoxy)-4-amino-2-pyrimidinyl]amino]benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[25] | |||
| Compound Name |
6-Methyl-7-N-[4-(2-morpholin-4-ylethoxy)phenyl]-5-N-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163612; BDBM50395271
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[26] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-N,4''-dimethylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL525921; BDBM50272799
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[27] | |||
| Compound Name |
Indigo
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Indigotin; Indigo Blue; Vat blue 1; Cystoceva; Diindogen; Pigment Blue 66; Vulcafix Blue R; Indigo Pure BASF; Indigo Ciba; Indigo Synthetic; Synthetic Indigo; Indigo J; Indigo N; Indigo P; Indigo Powder W; Vulcafor Blue A; Vynamon Blue A; Indigo VS; Indigo Ciba SL; Indigo NAC; Indigo PLN; Indigo NACCO; C.I. Vat Blue 1; Mitsui Indigo Pure; Mitsui Indigo Paste; indigo dye; Synthetic Indigo TS; Vulcol Fast Blue GL; Lithosol Deep Blue B; Vulcanosine Dark Blue L; Blue No. 201; D and C Blue No. 6; Lithosol deep blue V; Indigo,natural; Indigo Pure BASF Powder K; 11669 Blue; Monolite Fast Navy Blue BV; (2,2'-Biindoline)-3,3'-dione; D&C Blue No. 6; Modr kypova 1; Indigo (synthetic); C.I. 73000; NCI-C61392; Indigo, synthetic; UNII-1G5BK41P4F; C.I Vat blue 1; CI 73000; D&C Blue No.6; D&C Blue 6; D+C Blue No. 6; NSC-8645; D And C Blue Number 6; 1G5BK41P4F; CHEMBL599552; .DELTA.2,2'-Bipseudoindoxyl; MFCD00005722; NCGC00163355-01; C.I.73000; (delta(sup 2,2')-Biindoline)-3,3'-dione; DSSTox_CID_6279; 1H,1'H-[2,2']Biindolylidene-3,3'-dione; DSSTox_RID_78086; DSSTox_GSID_26279; Indigo (VAN); CI Vat Blue 1; CI Pigment Blue 66; Modr Kypova 1 [Czech]; delta2,2'-Bipseudoindoxyl; D & C Blue No. 6; Indigo (dye); SMR000857361; CCRIS 4379; HSDB 4372; (2E)-2,2'-biindole-3,3'(1H,1'H)-dione; delta(sup 2,2')-Bipseudoindoxyl; NSC 8645; C.I. pigment blue 66; EINECS 207-586-9; BRN 0088275; Indigoblau; cis-indigo; Pigment Indigo; AI3-09080; indigo B; Indigo Naturalis; (delta2,2'(3H,3'H)-Biindole)-3,3'-dione; Indigofera tinctoria; Indigotin (natural); Indigo [HPUS]; Indigo [HSDB]; Indigo [MI]; Indigo,(S); (delta2,2'-Biindoline)-3,3'-dione; D & C blue No 6; EC 207-586-9; [.DELTA.2,3'-dione; (2E)-2-(3-oxoindolin-2-ylidene)indolin-3-one; SCHEMBL42280; SCHEMBL56085; 5-24-08-00503 (Beilstein Handbook Reference); MLS001335921; MLS001335922; CHEMBL35479; D&C Blue No. 6 [II]; AO201 [INCI]; MEGxp0_001924; (2E)-2-(3-oxo-1H-indol-2-ylidene)-1H-indol-3-one; DTXSID3026279; Indigo (C.I. 73000); ACon1_002192; COHYTHOBJLSHDF-BUHFOSPRSA-; CTK2F4078; NSC8645; AO201; CI 73000 [INCI]; BCP26169; HY-N0335; Tox21_112052; Tox21_202545; BDBM50310357; s3876; AKOS015900171; AKOS015955899; Indigo, synthetic, Dye content 95 %; Tox21_112052_1; ZINC100014196; ZINC100513617; ZINC137102896; ZINC197603377; AC-8002; CCG-267072; MCULE-5170690249; NCGC00091633-01; NCGC00163355-02; NCGC00163355-03; NCGC00163355-04; NCGC00163355-05; NCGC00260094-01; [(D)(2,2')-Biindoline]-3,3'-dione; 2,2'-Biindole-3,3'(1H,1'H)-dione; 2-(3-oxoindolin-2-ylidene)indolin-3-one; (.DELTA.2,2'-Biindoline)-3,3'-dione; (E)-[2,2'-Biindolinylidene]-3,3'-dione; (Z)-[2,2'-Biindolinylidene]-3,3'-dione; [.DELTA.2,3'H)-Biindole]-3,3'-dione; CS-0008896; FT-0627197; I0212; N1630; ST50308404; (delta2,2'-Biindoline)-3,3'-dione (8CI); VAT BLUE 1 (INDIGO C.I. 73000); A14526; Q422662; SR-01000941903; (.DELTA.2,2'(3H,3'H)-Biindole)-3,3'-dione; 2-(3-Hydroxy-2H-indol-2-ylidene)-2H-indol-3-ol; J-521528; SR-01000941903-2; 3-CARBOXY-1,4-DIMETHYL-1H-PYRROLE-2-ACETICACID
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[28] | |||
| Compound Name |
4,6 Bis anilino pyrimidine deriv. 12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7639; CHEMBL328623
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[29] | |||
| Compound Name |
1-(6-Aminopyrimidin-4-yl)pyrrolo[2,3-b]pyridine-6-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348153; BDBM50432334
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
1-(2-Aminopyrimidin-4-yl)pyrrolo[3,2-b]pyridine-6-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348163; BDBM50432350
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
1-Pyrimidin-4-ylindole-6-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348177; BDBM50432361
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
4-[6-Chloro-3-(2-chloropyridin-3-yl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348152; BDBM50432335
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
4-[3-(3-Chlorophenyl)pyrrolo[3,2-c]pyridin-1-yl]pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348157; BDBM50432342
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
1-(6-Aminopyrimidin-4-yl)indole-6-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2348178; BDBM50432363
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 83000 nM
|
[30] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 8
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7595; CHEMBL101868; 4-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-6-N-(2-methoxyphenyl)pyrimidine-4,6-diamine; N-[4-[2-Hydroxy-3-(dimethylamino)propoxy]phenyl]-N'-(2-methoxyphenyl)pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[29] | |||
| Compound Name |
Pyrazole amide, 17
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL953263; CHEMBL499521; BDBM24638; ZINC40973176; AKOS012407858; 4-amino-N-(4-fluorophenyl)-1H-pyrazole-3-carboxamide; 4-amino-N-(4-fluorophenyl)-1H-pyrazole-5-carboxamide; 4-Amino-1H-pyrazole-3-carboxylic Acid (4-Fluoro-phenyl)-amide; 4-amino-1H-pyrazole-3-carboxylic acid (4-fluorophenyl)-amide; 4-amino-1H-pyrazole-3-carboxylic acid (4-fluorophenyl)amide; 4-amino-1H-pyrazole-3-carboxylic acid(4-fluoro-phenyl)-amide; 4-amino-1H-pyrazole-3-carboxylic acid(4-fluorophenyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[31] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-phenyl-N-methylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498705; BDBM50272835
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[27] | |||
| Compound Name |
3-Hydroxy-2-methyl-2-(2-methyl-4-oxo-6-phenyl-1,5,6,7-tetrahydroindol-3-yl)-6-phenyl-6,7-dihydro-5H-indol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3634037
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[32] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-N-methyl-4-(pyridin-4-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457179; BDBM50273141
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[27] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7588; CHEMBL317281; 4-N-(2,4-difluorophenyl)-6-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}pyrimidine-4,6-diamine; N-[4-[2-Hydroxy-3-(dimethylamino)propoxy]phenyl]-N'-(2,4-difluorophenyl)pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[33] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 6
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL99647; BDBM7593; N-[4-[2-Hydroxy-3-(dimethylamino)propoxy]phenyl]-N'-(2-chlorophenyl)pyrimidine-4,6-diamine; 4-N-(2-chlorophenyl)-6-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[29] | |||
| Compound Name |
2,2,2-Trifluoro-N-[4-(2-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2,2,2-trifluoro-N-(4-{2-methylimidazo[1,2-a]pyridin-3-yl}pyrimidin-2-yl)acetamide; Imidazo[1,2-a]pyridine deriv. 3; BDBM7643; CHEMBL102622; SCHEMBL5470162; 2-Methyl-3-[2-(trifluoroacetylamino)-4-pyrimidinyl]imidazo[1,2-a]pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[34] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222565; BDBM50325374; (S)-4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[35] | |||
| Compound Name |
3-(6-Chloro-5-fluoro-1-methyl-1H-indol-3-yl)-4-(7-methoxybenzofuran-3-yl)pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522760; SCHEMBL3133068; BDBM50267565; 3-(6-chloro-5-fluoro-1-methylindol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)pyrrole-2,5-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 99000 nM
|
[16] | |||
| Compound Name |
4,6 Bis anilino pyrimidine deriv. 9
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7636; CHEMBL101779; 4-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-6-N-(4-methoxyphenyl)pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
7-N-(4-Ethoxyphenyl)-6-methyl-5-N-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidine-5,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163604; SCHEMBL17921760; BDBM50395263
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7589; CHEMBL318188; 4-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-6-N-phenylpyrimidine-4,6-diamine; N-[4-[2-Hydroxy-3-(dimethylamino)propoxy]phenyl]-N'-phenylpyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
4-[6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1223203; BDBM50325369; 4-(6-(cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
N-(5-(Dibutylamino)-1H-indazol-3-yl)-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL258391; N-[5-(dibutylamino)-1H-indazol-3-yl]-2-phenylacetamide; BDBM50237866
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
1-[4-[4-[(4-Imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxyphenyl]piperazin-1-yl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1809192; BDBM50349771
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[2-(dimethylamino)ethyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
TCMDC-136678; CHEMBL588573; BDBM50325372; 4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(dimethylamino)ethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
7-Methyl-3-[2-(4-methylsulfonylphenyl)pyrimidin-4-yl]-1H-pyrrolo[2,3-c]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3421977; BDBM50081192
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
(E)-3-[1-[4-(3-Ethynylanilino)quinazolin-6-yl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL4080295; CHEMBL3218002
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
1-Methyl-3-[2-(4-methylsulfonylphenyl)pyrimidin-4-yl]pyrrolo[2,3-c]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3421976; BDBM50081193
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355482; BDBM50043416; ZINC17334508; AKOS008571954; Z31474376
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
3-[[5-Cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino]-4-methyl-N-(1,2-oxazol-3-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-{[5-cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino}-4-methyl-N-(1,2-oxazol-3-yl)benzamide; CHEMBL383172; 5-Cyanopyrimidine Derivative 3b; SCHEMBL16576397; BDBM16326; 3-{[5-cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino}-N-isoxazol-3-yl-4-methylbenzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 16
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7603; CHEMBL316809
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[33] | |||
| Compound Name |
4-[6-[(3,4-Dichlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-(2-pyrrolidin-1-ylethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222474; BDBM50325373; 4-(6-(3,4-dichlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4-[6-[(3-Chlorophenyl)methylamino]imidazo[1,2-b]pyridazin-3-yl]-N-[[(2S)-pyrrolidin-2-yl]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222992; BDBM50325368; (S)-4-(6-(3-chlorobenzylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
2-Amino-6-methoxypurine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-Methoxyguanine; O6-Methylguanine; 6-methoxy-9H-purin-2-amine; 6-O-Methylguanine; 6-Methoxy-7H-purin-2-amine; O-(6)-Methylguanine; 1H-Purin-2-amine, 6-methoxy-; Purine, 2-amino-6-methoxy-; 6-Methoxy-1H-purine-2-amine; O(sup 6)-Methylguanine; UNII-9B710FV2AE; 6-METHOXY-1H-PURIN-2-AMINE; MFCD00133009; 9B710FV2AE; CHEMBL226395; NSC37364; 9H-PURIN-2-AMINE, 6-METHOXY-; 6-methoxypurine-2-ylamine; O(6)-methylguanine; NSC 37364; O-Methylguanine; PubChem9244; ACMC-209fbs; O6-MeG; 2-amino-6-methoxy purine; NCIMech_000186; 6-O-Methylguanine, 97%; DSSTox_CID_29365; DSSTox_RID_83480; DSSTox_GSID_49405; MLS001074870; SCHEMBL231097; BDBM5470; DTXSID9049405; CTK7B2040; CTK8B1153; 6-Methoxy-7H-purin-2-amine #; O6-Substituted Guanine Deriv. 1; HMS2231D13; HMS3370E06; BCP30956; ZINC4770610; Tox21_202966; ANW-24134; BBL101282; CCG-35441; NSC-37364; SBB052058; STL555078; AKOS005257755; AKOS015914255; Purine, 2-amino-6-methoxy- (8CI); CS-W014307; LS20599; MB00722; MCULE-4539018382; KS-000011U3; NCGC00247006-01; NCGC00260512-01; NCI60_003482; SC-46314; SMR000568400; SY036172; TS-00127; 2-Amino-6-methoxypurine;6-O-Methylguanine; DB-045270; A1151; FT-0638008; FT-0671802; ST50298900; 6-O-Methylguanine (2-Amino-6-Methoxypurine); 535A835; A814660; Q4641549; W-201791; BRD-K99514692-001-06-7
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[39] | |||
| Compound Name |
10-Bromo-11H-indolo[3,2-c]quinoline-6-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3589661; BDBM50097868
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[40] | |||
| Compound Name |
6-(Cyclohexylmethoxy)-9-methyl-9h-purin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NU-6052; NU6052; CHEMBL94794; BDBM5565; CTK7E0950; NSC707617; O6-Cyclohexylmethyl-N9-methylguanine; NSC-707617; NCI60_038219; 2-amino-6-cyclohexylmethoxy-N(sup 9)-methylpurine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
(S)-4-(6-(Cyclopropylmethylamino)imidazo[1,2-b]pyridazin-3-yl)-N-(pyrrolidin-2-ylmethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222990; BDBM50325375
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[35] | |||
| Compound Name |
4,6-Bis anilino pyrimidine deriv. 5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7592; CHEMBL318485; N-[4-[2-Hydroxy-3-(dimethylamino)propoxy]phenyl]-N'-(2-fluorophenyl)pyrimidine-4,6-diamine; 4-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-6-N-(2-fluorophenyl)pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
6-(Adamantylamino)-2-[(3-hydroxypropyl)amino]-9-isopropylpurine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
purine deriv. 8; CHEMBL83719; BDBM10640; 3-{[6-(1-adamantylamino)-9-isopropyl-9H-purin-2-yl]amino}propan-1-ol; 3-[[9-Isopropyl-6-(adamantane-1-ylamino)-9H-purine-2-yl]amino]propane-1-ol; 3-{[6-(adamantan-1-ylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}propan-1-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
4,6 Bis anilino pyrimidine deriv. 10
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7637; CHEMBL102136; 4-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}-6-N-(4-methylphenyl)pyrimidine-4,6-diamine
Click to Show/Hide
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||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
4,6 Bis anilino pyrimidine deriv. 8
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM7635; CHEMBL318461; 4-N-(4-chlorophenyl)-6-N-{4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
N-(4-(N-(4,6-Dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3,4,5-triethoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3616877; ChemDiv1_009514; Oprea1_682608; HMS614A10; ZINC949263; BDBM50121658; AKOS001032776; MCULE-3033059372; ST50401949; SR-01000488633; SR-01000488633-1; F1750-0131
Click to Show/Hide
|
||||
| Activity |
IC50 = 105100 nM
|
[22] | |||
| Compound Name |
Indazole-benzimidazole, 15
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL474441; BDBM35179
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[43] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-3-(pyridin-3-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515051; BDBM50273142
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[27] | |||
| Compound Name |
(5Z)-2-Imino-5-[[5-(4-morpholin-4-ylsulfonylphenyl)furan-2-yl]methylidene]-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL233763
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[44] | |||
| Compound Name |
1H-Indazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
INDAZOLE; 1H-Benzopyrazole; 2H-indazole; Isoindazole; 2-Azaindole; 1,2-Diazaindene; 1,2-Benzodiazole; 1H-indazol; Benzopyrazole; Azaindole; UNII-7C4VQE5C03; 1,2-Benzopyrazole; MFCD00005691; 7C4VQE5C03; Indazole, 96%; WLN: T56 BMNJ; 1,2-Diazaindene (VAN); EINECS 205-978-4; NSC 26336; indazol; 2-Azoindole; 1-H-indazole; Indazole, 5; Indazole, 6; NSC90357; BENZPYRAZOL; zlchem 598; ACMC-20aixv; Indazole, 98%; PubChem15665; SCHEMBL6295; KSC205O5T; CHEMBL86795; SCHEMBL3056528; SCHEMBL5376344; SCHEMBL5376627; SCHEMBL5376678; SCHEMBL5379372; SCHEMBL5383265; DTXSID4075374; SCHEMBL17515466; BDBM24627; CTK0J2806; CTK1A5759; ZLD0045; ACT05802; BCP27336; NSC26336; ANW-75473; MFCD20483705; NSC-26336; NSC-90357; RW3869; SBB040063; STL371246; ZINC16052862; AKOS000271187; CS-W008689; LS20969; MCULE-6962938625; PB23156; PS-4750; VZ21733; AK-49124; BR-49124; SC-27069; SY001125; AB0015286; DB-024400; A5299; AM20060873; BB 0219702; FT-0607899; FT-0627194; I0278; ST50177678; EN300-44212; KS-00000729; 6945-EP2270010A1; 6945-EP2272517A1; 6945-EP2272813A2; 6945-EP2272828A1; 6945-EP2272832A1; 6945-EP2275395A2; 6945-EP2275401A1; 6945-EP2275404A1; 6945-EP2275412A1; 6945-EP2277858A1; 6945-EP2280000A1; 6945-EP2280012A2; 6945-EP2281563A1; 6945-EP2281818A1; 6945-EP2284157A1; 6945-EP2284920A1; 6945-EP2285783A1; 6945-EP2289890A1; 6945-EP2292586A2; 6945-EP2292592A1; 6945-EP2292604A2; 6945-EP2292611A1; 6945-EP2295412A1; 6945-EP2295413A1; 6945-EP2295429A1; 6945-EP2295432A1; 6945-EP2295433A2; 6945-EP2295550A2; 6945-EP2298738A1; 6945-EP2298767A1; 6945-EP2298770A1; 6945-EP2301923A1; 6945-EP2301937A1; 6945-EP2305250A1; 6945-EP2305648A1; 6945-EP2305651A1; 6945-EP2305675A1; 6945-EP2308510A1; 6945-EP2308562A2; 6945-EP2308840A1; 6945-EP2308848A1; 6945-EP2308854A1; 6945-EP2311824A1; 6945-EP2311825A1; 6945-EP2314575A1; 6945-EP2316459A1; 6945-EP2316470A2; 6945-EP2316832A1; 6945-EP2316833A1; 6945-EP2371811A2; 6945-EP2372804A1; 6945-EP2378585A1; B-1767; 38318-EP2295433A2; 38318-EP2303878A1; 38318-EP2311837A1; 53182-EP2292630A1; 53182-EP2305651A1; 53182-EP2308854A1; 90623-EP2270505A1; 90623-EP2272972A1; 90623-EP2272973A1; 90623-EP2275411A2; 90623-EP2277872A1; 90623-EP2281815A1; 90623-EP2292606A1; 90623-EP2295413A1; 90623-EP2295429A1; 90623-EP2305219A1; 90623-EP2305640A2; AB00376876-02; 103668-EP2300437A1; 271I443; AC-907/25014165; Q417106; J-504679; F0918-7060; F1918-0009; Z276614452
Click to Show/Hide
|
||||
| Activity |
IC50 = 185000 nM
|
[45] | |||
| Compound Name |
5-Fluoro-3-(2-indol-1-yl-ethyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557321; BDBM50297276; 5'-Fluoro[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
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||||
| Activity |
IC50 = 200000 nM
|
[46] | |||
| Compound Name |
Click to Show/Hide
|
Compound Info | |||
| Activity |
IC50 = 91000 nM
|
[32] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 78 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
7,8,3',4'-tetrahydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7,8,3',4'-tetrahydroxyflavone; 3440-24-2; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4-one; 3',4',7,8-Tetrahydroxyflavone; CHEMBL222541; ARYCMKPCDNHQCL-UHFFFAOYSA-N; ST059620; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxychromen-4-one; AC1LEMTC; AC1Q6AJ1; SCHEMBL35318; CTK4H2335; ZINC57844; DTXSID20350973; 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4h-chromen-4-on; CHEBI:125596; 7,8,3'',4''-tetrahydroxyflavone; BDBM50157547; AKOS024283046; ACM3440242; MCULE-5496936655; ZB002260; DB-048618; FT-0614178; C-57754
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[47] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)biphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521733; N-(2-(1H-Indol-3-yl)ethyl)biphenyl-4-carboxamide; N-[2-(1H-indol-3-yl)ethyl]biphenyl-4-carboxamide; AC1LG1FS; Oprea1_829316; Oprea1_192683; MolPort-001-987-537; ZINC285233; STK129364; BDBM50272836; AKOS000554028; MCULE-1062167425; NCGC00304458-01; BAS 03049800; ST45172084; AB01300868-01; N-[2-(1H-indol-3-yl)ethyl]-4-phenylbenzamide; N-(2-indol-3-ylethyl)(4-phenylphenyl)carboxamide; Biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 855000 nM
|
[27] | |||
| Compound Name |
5-[(4-Ethoxyphenyl)amino]-2-methylbenzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40362; CTK6G2128; 5-(4-ethoxyanilino)-2-methyl-1,3-benzothiazole-4,7-dione; BDBM50086653; 5-(4-Ethoxy-phenylamino)-2-methyl-benzothiazole-4,7-dione; 2-Methyl-5-(4-ethoxyphenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-(4-Bromo-phenylamino)-2-methyl-benzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL142788; BDBM50086651; 2-Methyl-5-(4-bromophenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
2-Methyl-5-(phenylamino)benzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38693; 5-anilino-2-methyl-1,3-benzothiazole-4,7-dione; SCHEMBL14040854; CTK6C5863; BDBM50086658; 2-Methyl-5-phenylamino-benzothiazole-4,7-dione; 2-Methyl-5-(phenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-[(4-Chlorophenyl)amino]-2-methylbenzothiazole-4,7-dione
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL38694; SCHEMBL14040848; CTK6H0605; 5-(4-chloroanilino)-2-methyl-1,3-benzothiazole-4,7-dione; BDBM50086657; 5-(4-Chloro-phenylamino)-2-methyl-benzothiazole-4,7-dione; 2-Methyl-5-(4-chlorophenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-(4-Hydroxy-phenylamino)-2-methyl-benzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL140584; BDBM50086654; 2-Methyl-5-(4-hydroxyphenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-(4-Methoxy-phenylamino)-2-methyl-benzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL143570; BDBM50086652; 2-Methyl-5-(4-methoxyphenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-(4-Iodo-phenylamino)-2-methyl-benzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL142789; BDBM50086650; 2-Methyl-5-(4-iodophenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
5-[(4-Fluorophenyl)amino]-2-methylbenzothiazole-4,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40326; SCHEMBL14040845; CTK7C0879; 5-(4-fluoroanilino)-2-methyl-1,3-benzothiazole-4,7-dione; BDBM50086656; 5-(4-Fluoro-phenylamino)-2-methyl-benzothiazole-4,7-dione; 2-Methyl-5-(4-fluorophenylamino)-4,7-dihydrobenzothiazole-4,7-dione
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[48] | |||
| Compound Name |
4-(5-(Piperidin-1-ylmethyl)-4-(5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)-4,5-dihydro-1,2,3-triazol-1-yl)-4,5-dihydro-1,2,5-oxadiazol-3-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL197226; BDBM50175103
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[49] | |||
| Compound Name |
N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
PD153035; PD-153035; pd 153035; UNII-TC62B68RSL; 4-(3-BROMOANILINO)-6,7-DIMETHOXYQUINAZOLINE; AG-1517; SU 5271; 4-(3-bromophenylamino)-6,7-dimethoxyquinazoline; AG 1517; NSC-669364; PD-153035 free base; SU-5271; TC62B68RSL; CHEMBL29197; 153436-54-5 (free base); (3-Bromophenyl)(6,7-dimethoxyquinazolin-4-yl)amine; 4-QUINAZOLINAMINE, N-(3-BROMOPHENYL)-6,7-DIMETHOXY-; 4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline; C16H14BrN3O2; 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline; SR-01000597835; WHI-P-79; InSolution PD 153035; GI 230329A; PubChem22449; Tocris-1037; SCHEMBL9423; AG-1517 HCl; BDBM3032; LSPANGZZENHZNJ-UHFFFAOYSA-; AOB6127; DTXSID80165328; ZINC600292; BCP00569; EX-A1235; KS-00000I0V; ANW-48127; HSCI1_000100; MFCD00934896; QC-948; s6546; AKOS003676410; BCP9001062; CS-0143; DS-1673; VZ27722; NCGC00024956-01; NCGC00024956-02; NCGC00024956-04; NCGC00024956-18; NCGC00024956-19; AC-32897; AK-50931; AM808088; BR-50931; HY-14346; SC-27623; AB0022472; DB-028592; FT-0643505; W3343; PD 153035(AG-1517); K00043; N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-; S-7071; J-009016; J-523873; SR-01000597835-2; 4-Quinazolinamine,N-(3-bromophenyl)-6,7-dimethoxy-; BRD-K26603252-001-01-9; Q27163047; PD 153035 - CAS 153436-54-5; PD 153035; SU 5271; 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[50] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-tert-butylbiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL525530; BDBM50272874
Click to Show/Hide
|
||||
| Activity |
IC50 = 262000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-methoxy-N-methylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL525538; BDBM50272834
Click to Show/Hide
|
||||
| Activity |
IC50 = 289000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-fluorobiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456378; SCHEMBL13942737; BDBM50273075
Click to Show/Hide
|
||||
| Activity |
IC50 = 296000 nM
|
[27] | |||
| Compound Name |
5-N-(4-Aminocyclohexyl)-7-N-(2-chlorophenyl)-6-ethylpyrazolo[1,5-a]pyrimidine-5,7-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2163605; BDBM50395264
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[26] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-fluorobiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456584; SCHEMBL13942743; BDBM50273076
Click to Show/Hide
|
||||
| Activity |
IC50 = 310000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2-(pyridin-3-yl)phenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457390; SCHEMBL13942725; BDBM50273144
Click to Show/Hide
|
||||
| Activity |
IC50 = 312000 nM
|
[27] | |||
| Compound Name |
[3-(4-Fluorophenyl)phenyl]-(1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457191; BDBM50272999; (3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(4''-fluorobiphenyl-3-yl)methanone
Click to Show/Hide
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||||
| Activity |
IC50 = 318000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-methoxybiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456113; SCHEMBL13943078; BDBM50273109
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|
||||
| Activity |
IC50 = 321000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-fluorobiphenyl-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455931; SCHEMBL13942741; BDBM50273039
Click to Show/Hide
|
||||
| Activity |
IC50 = 335000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-methylbiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517154; SCHEMBL13943089; BDBM50273107
Click to Show/Hide
|
||||
| Activity |
IC50 = 340000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2-(pyridin-4-yl)phenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457180; SCHEMBL13942735; BDBM50273143
Click to Show/Hide
|
||||
| Activity |
IC50 = 354000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(4''-fluorobiphenyl-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457401; SCHEMBL13942730; BDBM50272995
Click to Show/Hide
|
||||
| Activity |
IC50 = 357000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-methoxybiphenyl-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456796; SCHEMBL13943082; BDBM50273072
Click to Show/Hide
|
||||
| Activity |
IC50 = 362000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-2''-methoxybiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456760; BDBM50272917
Click to Show/Hide
|
||||
| Activity |
IC50 = 375000 nM
|
[27] | |||
| Compound Name |
[2-(3-Methylphenyl)phenyl]-(1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515356; BDBM50272998; (3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-methylbiphenyl-2-yl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 386000 nM
|
[27] | |||
| Compound Name |
3-(2-Indol-1-yl-ethyl)-5-methyl-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569847; BDBM50297278; 5'-Methyl[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[46] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-methylbiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL463384; SCHEMBL13943080; BDBM50273106
Click to Show/Hide
|
||||
| Activity |
IC50 = 405000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-3''-methylbiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456121; SCHEMBL13942344; BDBM50272919
Click to Show/Hide
|
||||
| Activity |
IC50 = 406000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-3''-fluorobiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456964; BDBM50272918
Click to Show/Hide
|
||||
| Activity |
IC50 = 417000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-methoxybiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456112; SCHEMBL13943086; BDBM50273108
Click to Show/Hide
|
||||
| Activity |
IC50 = 424000 nM
|
[27] | |||
| Compound Name |
5-Chloro-1-[2-(1H-indol-3-yl)-ethyl]-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557049; BDBM50297280; 5-Chloro[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
|
||||
| Activity |
IC50 = 430000 nM
|
[46] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-fluorobiphenyl-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL457190; SCHEMBL13942739; BDBM50272997
Click to Show/Hide
|
||||
| Activity |
IC50 = 434000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(4''-fluorobiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456995; SCHEMBL13942742; BDBM50273074
Click to Show/Hide
|
||||
| Activity |
IC50 = 438000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-methylbiphenyl-3-yl)methanon
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL458075; SCHEMBL13943085; BDBM50273041
Click to Show/Hide
|
||||
| Activity |
IC50 = 465000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(4''-methylbiphenyl-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456143; SCHEMBL13943091; BDBM50273040
Click to Show/Hide
|
||||
| Activity |
IC50 = 466000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-fluorobiphenyl-2-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL515674; SCHEMBL13942734; BDBM50272996
Click to Show/Hide
|
||||
| Activity |
IC50 = 480000 nM
|
[27] | |||
| Compound Name |
1-[2-(1H-Indol-3-yl)-ethyl]-5-methyl-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL556095; BDBM50297281; 5-Methyl[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[46] | |||
| Compound Name |
3',4'-Dihydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(3,4-dihydroxyphenyl)-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)chromen-4-one; UNII-KOH101S66V; 3',4'-Dihydroxy Flavone; 3'',4''-dihydroxyflavone; 3,4-DIHYDROXYFLAVONE; CHEMBL222556; KOH101S66V; 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-; MFCD00017600; Dihydroxyflavone, 3',4'-; PubChem9842; ACMC-20anf0; Oprea1_301189; 3'',4''-dihydroxy flavone; SCHEMBL345706; SPECTRUM1505139; CTK4I4830; ZINC57659; DTXSID70194349; BDBM50157555; AKOS001656361; MCULE-2401542699; NCGC00096030-01; AS-64531; ST059621; 2-[3,4-bis(oxidanyl)phenyl]chromen-4-one; DB-049758; D4884; EU-0042517; FT-0614330; Y2021; 2-(3,4-dihydroxyphenyl)-1-benzopyran-4-one; A825557; SR-01000471684; 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-; SR-01000471684-1; W-202706; Q27282353
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[47] | |||
| Compound Name |
5-Fluoro-1-[2-(1H-indol-3-yl)-ethyl]-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557525; BDBM50297279; 5-Fluoro[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[46] | |||
| Compound Name |
1-[2-(1H-Indol-3-yl)ethyl]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC661244; 1-(2-(1H-Indol-3-yl)ethyl)-1H-indole; CHEMBL552214; 1,3'-Ethylenebis(1H-indole); CTK5J7038; BDBM50297275; 3-[2-Indol-1-yl-ethyl]-1H-indole; NSC-661244; NCI60_021372
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[46] | |||
| Compound Name |
5-Chloro-3-(2-indol-1-yl-ethyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563159; BDBM50297277; 5'-Chloro[1,3'-ethylenebis(1H-indole)]
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[46] | |||
| Compound Name |
Fascaplysine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Fascaplysin; Fascaplysin chloride; CHEMBL258765; Fascaplisine; NSC622398; NSC-622398; 12,13-dihydro-13-oxo-pyrido[1,2-a:3,4-b']diindol-5-ium, monochloride; GNF-PF-1458; Fascaplysin, Synthetic; SCHEMBL15531753; HMS3229G10; Pyrido(1,2a:3,4-b')diindol-5-ium, 12,13-dihydro-13-oxo-, chloride; CCG-206840; Fascaplysin, Synthetic - CAS 114719-57-2; J-003125; Pyrido[1,4-b']diindol-5-ium, 12,13-dihydro-13-oxo-,chloride; Pyrido[1,2-a:3,4-b']diindol-5-ium, 12,13-dihydro-13-oxo-, chloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-N-methyl-[1,1'-biphenyl]-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CA-224; CHEMBL213805; SCHEMBL13941762; CA224; BDBM50188071; A14414; N-[2-(1H-Indol-3-yl)ethyl]-N-methyl-4-phenylbenzamide; N-Methyl-N-[2-(1H-indole-3-yl)ethyl]-4-phenylbenzamide; biphenyl-4-carboxylic acid [2-(1H-indol-3-yl)-ethyl]-methyl-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 521000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(3''-fluorobiphenyl-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL509499; SCHEMBL13942733; BDBM50273038
Click to Show/Hide
|
||||
| Activity |
IC50 = 611000 nM
|
[27] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(2''-methylbiphenyl-3-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL458076; SCHEMBL13943087; BDBM50273042
Click to Show/Hide
|
||||
| Activity |
IC50 = 665000 nM
|
[27] | |||
| Compound Name |
1-(5-Methyl-2,3-dihydroindol-1-yl)-2-(5-methyl-1H-indol-3-yl)ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559882; BDBM50297274; 1-(5-Methyl-2,3-dihydro-indol-1-yl)-2-(5-methyl-1Hindol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 710000 nM
|
[46] | |||
| Compound Name |
(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)(4''-methylbiphenyl-4-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL463383; SCHEMBL13943083; BDBM50273105
Click to Show/Hide
|
||||
| Activity |
IC50 = 736000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-tert-butyl-N-methylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498521; BDBM50272800
Click to Show/Hide
|
||||
| Activity |
IC50 = 745000 nM
|
[27] | |||
| Compound Name |
1-(1H-Indol-3-yl)-2-(indolin-1-yl)ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC661247; CHEMBL556712; CTK7F3429; ZINC1638135; 2-(2,3-Dihydro-1H-indol-1-yl)-1-(1H-indol-3-yl)-2-oxoethanone; BDBM50297265; AKOS005133835; MCULE-9008753066; NSC-661247; NCI60_021375; SR-01000134577; SR-01000134577-1; 1-indolin-1-yl-2-(1H-indol-3-yl)ethane-1,2-dione; F0675-0117; 1-(2,3-Dihydro-indol-1-yl)-2-(1H-indol-3-yl)-ethane-1,2-dione; 1-(2,3-dihydro-1h-indol-1-yl)-2-(1h-indol-3-yl)ethane-1,2-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 760000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-fluorobiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL496481; BDBM50272837
Click to Show/Hide
|
||||
| Activity |
IC50 = 764000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-tert-butylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498710; BDBM50272870
Click to Show/Hide
|
||||
| Activity |
IC50 = 790000 nM
|
[27] | |||
| Compound Name |
1-(5-Fluoro-2,3-dihydro-indol-1-yl)-2-(1H-indol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540971; BDBM50297269
Click to Show/Hide
|
||||
| Activity |
IC50 = 790000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-methylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL496482; BDBM50272838
Click to Show/Hide
|
||||
| Activity |
IC50 = 816000 nM
|
[27] | |||
| Compound Name |
1-(5-Fluoro-2,3-dihydroindol-1-yl)-2-(5-fluoro-1H-indol-3-yl)ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559683; BDBM50297272; 1-(5-Fluoro-2,3-dihydro-indol-1-yl)-2-(5-fluoro-1Hindol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 816000 nM
|
[46] | |||
| Compound Name |
5-Chloro-3-[2-(5-chloro-3a,7a-dihydro-indol-1-yl)-ethyl]-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549303; BDBM50297282
Click to Show/Hide
|
||||
| Activity |
IC50 = 862000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-fluoro-N-methylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498520; BDBM50272798
Click to Show/Hide
|
||||
| Activity |
IC50 = 875000 nM
|
[27] | |||
| Compound Name |
5-Fluoro-3-[2-(5-fluoro-3a,7a-dihydro-indol-1-yl)-ethyl]-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563948; BDBM50297264
Click to Show/Hide
|
||||
| Activity |
IC50 = 895000 nM
|
[46] | |||
| Compound Name |
1-(1H-Indol-3-yl)-2-(5-methyl-2,3-dihydro-indol-1-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561136; BDBM50297271
Click to Show/Hide
|
||||
| Activity |
IC50 = 910000 nM
|
[46] | |||
| Compound Name |
1-(5-Chloro-2,3-dihydroindol-1-yl)-2-(5-chloro-1H-indol-3-yl)ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL552136; BDBM50297273; 1-(5-Chloro-2,3-dihydro-indol-1-yl)-2-(5-chloro-1Hindol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 915000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-methoxybiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456965; SCHEMBL13942999; BDBM50272915
Click to Show/Hide
|
||||
| Activity |
IC50 = 921000 nM
|
[27] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-3''-methoxybiphenyl-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456759; SCHEMBL13942343; BDBM50272916
Click to Show/Hide
|
||||
| Activity |
IC50 = 926000 nM
|
[27] | |||
| Compound Name |
1,2-Bis-(indol-1-yl)-ethane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549792; 1,1'-Ethylenedi(1H-indole); SCHEMBL11366447; BDBM50297259
Click to Show/Hide
|
||||
| Activity |
IC50 = 940000 nM
|
[46] | |||
| Compound Name |
1,5-Bis-(indol-1-yl)-pentane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL560393; 1,1'-Pentamethylenebis(1H-indole); BDBM50297262; 1,1'-pentane-1,5-diylbis(1 h -indole)
Click to Show/Hide
|
||||
| Activity |
IC50 = 950000 nM
|
[46] | |||
| Compound Name |
1-(2,3-Dihydro-indol-1-yl)-2-(5-methyl-1H-indol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562198; BDBM50297268
Click to Show/Hide
|
||||
| Activity |
IC50 = 951000 nM
|
[46] | |||
| Compound Name |
5-Methyl-3-[2-(5-methyl-3a,7a-dihydro-indol-1-yl)-ethyl]-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL560278; BDBM50297283
Click to Show/Hide
|
||||
| Activity |
IC50 = 960000 nM
|
[46] | |||
| Compound Name |
1-(5-Chloro-1H-indol-3-yl)-2-(2,3-dihydro-indol-1-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551936; BDBM50297267
Click to Show/Hide
|
||||
| Activity |
IC50 = 985000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)biphenyl-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498130; BDBM50272872
Click to Show/Hide
|
||||
| Activity |
IC50 = 1002000 nM
|
[27] | |||
| Compound Name |
1-(4-Indol-1-ylbutyl)indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558849; NSC243874; 1,4-di(indol-1-yl)butane; Butane, 1,4-di(1-indolyl)-; 1,4-Bis-(indol-1-yl)-butane; DTXSID00311562; BDBM50297261; NSC-243874; 1,1'-butane-1,4-diylbis(1 h -indole); 1-[4-(1H-Indol-1-yl)butyl]-1H-indole #
Click to Show/Hide
|
||||
| Activity |
IC50 = 1026000 nM
|
[46] | |||
| Compound Name |
1-(5-Chloro-2,3-dihydro-indol-1-yl)-2-(1H-indol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558601; BDBM50297270
Click to Show/Hide
|
||||
| Activity |
IC50 = 1030000 nM
|
[46] | |||
| Compound Name |
1,3-Bis-(indol-1-yl)-propane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557456; 1,3-di(1h-indol-1-yl)propane; BDBM50297260
Click to Show/Hide
|
||||
| Activity |
IC50 = 1070000 nM
|
[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-methoxybiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL527039; BDBM50272871
Click to Show/Hide
|
||||
| Activity |
IC50 = 1085000 nM
|
[27] | |||
| Compound Name |
Biphenyl-3-yl(3,4-dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456797; BDBM50273073
Click to Show/Hide
|
||||
| Activity |
IC50 = 1109000 nM
|
[27] | |||
| Compound Name |
1-(2,3-Dihydro-indol-1-yl)-2-(5-fluoro-1H-indol-3-yl)-ethane-1,2-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551612; BDBM50297266
Click to Show/Hide
|
||||
| Activity |
IC50 = 1160000 nM
|
[46] | |||
| Compound Name |
1,6-Bis-(indol-1-yl)-hexane
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL549850; BDBM50297263; 1,1'-hexane-1,6-diylbis(1 h -indole)
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| Activity |
IC50 = 1210000 nM
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[46] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4''-fluorobiphenyl-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL497454; SCHEMBL13942356; BDBM50272873
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| Activity |
IC50 = 1216000 nM
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[27] | |||
| Compound Name |
1-(2-(2,3-Dihydro-1H-indol-1-yl)ethyl)indoline
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Investigative | Compound Info | ||
| Synonyms |
NSC663299; CHEMBL557050; 1,1'-Ethylenebisindoline; (2-indolinylethyl)indoline; Oprea1_572591; MLS000104475; SCHEMBL7940135; 1-[2-(2,3-dihydroindol-1-yl)ethyl]-2,3-dihydroindole; CTK5J7040; DTXSID70327514; 1,1'-ethane-1,2-diyldiindoline; 1-(2-indolin-1-ylethyl)indoline; HMS2285N18; ZINC254605; BDBM50297284; STK386833; AKOS005305839; MCULE-2206045205; NSC-663299; NCI60_021742; SMR000054410; 1,2-Bis-(2,3-dihydro-indol-1-yl)-ethane; EU-0066808; ST50862311; SR-01000389841; 1,1'-ethane-1,2-diylbis(2,3-dihydro-1H-indole); SR-01000389841-1
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| Activity |
IC50 = 1230000 nM
|
[46] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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