Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T79031 | Target Info | |||
| Target Name | Beta-secretase 1 (BACE1) | ||||
| Synonyms |
Membrane-associated aspartic protease 2; Memapsin-2; KIAA1149; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; BACE; Aspartyl protease 2; Asp 2; ASP2
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| Target Type | Clinical trial Target | ||||
| Gene Name | BACE1 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 289 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
PF-06751979
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|
Phase 1 | Compound Info | ||
| Synonyms |
ZLZUHACSRMOLLV-RAALSFIWSA-N; 1818339-66-0; UNII-1Y0Y126GUG; 1Y0Y126GUG; US9315520, Example 1; CHEMBL3952064; US9315520, Example 2; US9315520, Comparator 1; SCHEMBL17162186; BDBM223395; HY-112157; CS-0043501; US9315520, 1; N-(2-((4aR,6S,8aR)-2-Amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano(3,4-d)(1,3)thiazin-8a-yl)thiazol-4-yl)-5-(difluoromethoxy)pyridine-2-carboxamide; N-{2-[(4aR,6S,8aR)-2-Amino-6-methyl-4,4a,5,6-tetrahydropyrano[3,4-d][1,3]thiazin-8a(8H)-yl]-1,3-thiazol-4-yl}-5-(difluoromethoxy)pyridine-2-carb
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
IMPERATORIN
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Investigative | Compound Info | ||
| Synonyms |
IMPERATORIN; 482-44-0; Ammidin; Marmelosin; Pentosalen; 8-Isoamylenoxypsoralen; 8-Isopentenyloxypsoralene; Marmelide; NSC 402949; CCRIS 4346; UNII-K713N25C78; 9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one; HSDB 3497; EINECS 207-581-1; 9-(3-Methylbut-2-enyloxy)furo(3,2-g)chromen-7-one; AI3-61725; CHEBI:5885; CHEMBL453805; OLOOJGVNMBJLLR-UHFFFAOYSA-N; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-; 9-(3-Methylbut-2-enyloxy)furo[3,2-g]chromen-7-one; K713N25C78
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| Activity |
IC50 = 91800 nM
|
[2] | |||
| Compound Name |
2-{[3-Cyano-6-(4-fluorophenyl)-4-phenyl-2-pyridinyl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1504056; AK-777/36504062; MLS000587514; HMS2595E18; HMS3382J10; ZINC8448587; BDBM50346127; RSC007417; STK524323; STL318123; AKOS003679626; AKOS022104998; MCULE-7874881123; SMR000211470; ST51061825
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
N-(2-Chlorophenyl)-2-({6-[(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)amino]-1,3-benzothiazol-2-yl}sulfanyl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1270082; Oprea1_287228; Oprea1_523968; AN-648/15098040; MLS001240045; HMS2983O03; ZINC8445161; BDBM50329125; MCULE-1483222486; SMR000673413; MLS-0384162.0001
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| Activity |
IC50 = 50000 nM
|
[4] | |||
| Compound Name |
Rac-3-[(3-Butylureido)methyl]benzyl-5-isobutyl-5-phenethyl-2-iminohydantoin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL569427; SCHEMBL7524106; BDBM50300234
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| Activity |
IC50 = 50000 nM
|
[5] | |||
| Compound Name |
2-[4-(4-Chlorophenyl)-3-cyano-6-(4-methoxyphenyl)pyridin-2-yl]sulfanyl-N-naphthalen-2-yl-N-phenylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782312; BDBM50346128
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| Activity |
IC50 = 50000 nM
|
[3] | |||
| Compound Name |
Chembl4204435
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Investigative | Compound Info | ||
| Synonyms |
Terretonin D; BDBM50459491
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2H-Phenanthro(1,2-c)pyran-2-carboxylic acid, 1,4,4a,4b,5,7,8,9,10,10a,10b,11,12,12a-tetradecahydro-6,10b-dihydroxy-2,4b,7,7,10a,12a-hexamethyl-12-methylene-1,4,5,8-tetraoxo-, methyl ester, (2R,4aR,4bS,10aS,10bS,12aR)-
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Investigative | Compound Info | ||
| Synonyms |
Terretonin; UNII-8795XG0M1T; CHEMBL4208768; 8795XG0M1T; BDBM50459483; Q27225281
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(E)-3-(3,4-Dihydroxyphenyl)-N-[[1-[[(3S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-3-yl]methyl]triazol-4-yl]methyl]prop-2-enamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884327; BDBM50209785
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Chembl4215650
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene G; BDBM50459494
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
CID 58197581
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1464266; SCHEMBL7882691; SCHEMBL7893526; CHEMBL3968267; CHEMBL3968463; BDBM113280; BDBM113287; US8633212, 58; US8633212, 65
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| Activity |
IC50 = 50000 nM
|
[8] | |||
| Compound Name |
Chembl4209304
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene M; BDBM50459495
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-({6-[(4,6-Dimorpholin-4-yl-1,3,5-triazin-2-yl)amino]-1,3-benzothiazol-2-yl}sulfanyl)-N-(4-ethoxyphenyl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1269611; Oprea1_797273; AN-648/15099033; ZINC8445172; BDBM50329126; AKOS002059047; MCULE-5242340036; SR-01000572744; SR-01000572744-1
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
S-Benzo[d]thiazol-2-yl 2-(2-(2-(4-methoxybenzamido)benzamido)-4-(methylthio)butanoyl)hydrazinecarbothioate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164332; BDBM50320682
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| Activity |
IC50 = 50000 nM
|
[9] | |||
| Compound Name |
2-[[6-[[4,6-Di(piperidin-1-yl)-1,3,5-triazin-2-yl]amino]-1,3-benzothiazol-2-yl]sulfanyl]-N-phenylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271294; BDBM50329123; 2-(6-(4,6-di(piperidin-1-yl)-1,3,5-triazin-2-ylamino)benzo[d]thiazol-2-ylthio)-N-phenylacetamide
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
Chembl4204943
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene K; BDBM50459481
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4216625
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene L; BDBM50459490
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4213164
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Investigative | Compound Info | ||
| Synonyms |
BDBM50459496
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-Benzylsulfonyl-N-[(2S,3R)-4-[[(2S)-1-(cyclohexylamino)-1-oxopropan-2-yl]amino]-3-hydroxy-1-phenylbutan-2-yl]benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1210338; BDBM50322897
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| Activity |
IC50 = 50000 nM
|
[10] | |||
| Compound Name |
4-({2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-acetylamino)-6-methyl-heptanoylamino]-3-methyl-butyrylamino}-methyl)-benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL53024; BDBM50127432
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| Activity |
IC50 = 50000 nM
|
[11] | |||
| Compound Name |
Chembl4203972
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene H; BDBM50459488
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4211731
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene D; BDBM50459486
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Chembl4218091
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Investigative | Compound Info | ||
| Synonyms |
BDBM50459485
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
5-{1-[2-(1-{1-[3-Carboxy-1-(1-carboxy-2-phenyl-ethylcarbamoyl)-propylcarbamoyl]-ethylcarbamoyl}-2-methyl-propylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-pentanoic acid methyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL48843; BDBM50127415
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| Activity |
IC50 = 50000 nM
|
[11] | |||
| Compound Name |
Chembl4205875
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Investigative | Compound Info | ||
| Synonyms |
BDBM50459493
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
9-(3-Naphthalen-2-ylsulfanyl-2-piperazin-1-ylpropyl)carbazole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058873; BDBM50388755
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| Activity |
IC50 ~ 50000 nM
|
[12] | |||
| Compound Name |
Chembl4218151
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Investigative | Compound Info | ||
| Synonyms |
Asperterpene I; BDBM50459482
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-Benzyl-2-(6-(4,6-dimorpholino-1,3,5-triazin-2-ylamino)benzo[d]thiazol-2-ylthio)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1269866; CDS1_002362; ChemDiv1_015098; Oprea1_505705; DivK1c_003402; HMS629O06; BDBM50329124; ZINC29747557; AKOS002073068; MCULE-3658311660; SR-01000572745; SR-01000572745-1
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| Activity |
IC50 = 50000 nM
|
[4] | |||
| Compound Name |
CID 53375047
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3673218; SCHEMBL12318157; BDBM160690; US9045500, 12
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| Activity |
IC50 = 50000 nM
|
[13] | |||
| Compound Name |
2-[(6-{[4,6-Di(morpholin-4-yl)-1,3,5-triazin-2-yl]amino}-1,3-benzothiazol-2-yl)sulfanyl]-N-(2,4,6-trimethylphenyl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1269615; ZINC8438211; BDBM50329110; STK046865; AKOS005384853; MCULE-6804211795; 2-(6-(4,6-dimorpholino-1,3,5-triazin-2-ylamino)benzo[d]thiazol-2-ylthio)-N-mesitylacetamide
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| Activity |
IC50 ~ 50000 nM
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[4] | |||
| Compound Name |
Chembl4213706
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Investigative | Compound Info | ||
| Synonyms |
BDBM50459492
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Tert-butyl N-[(2S)-1-[[(2S)-4-[[(4S,5S,7R)-8-[[(2S)-1-(benzylamino)-3-methyl-1-oxobutan-2-yl]amino]-5-hydroxy-2,7-dimethyl-8-oxooctan-4-yl]amino]-1-methylsulfanyl-3-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2299406; BDBM50489054
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| Activity |
Ki = 50118.72 nM
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[14] | |||
| Compound Name |
CID 90056348
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3650819; SCHEMBL15589427; BDBM149907; US8975415, RP188
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| Activity |
IC50 = 50600 nM
|
[15] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[4-(4-methylthiophen-2-yl)phenyl]cyclopropyl]pyrimidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169946; BDBM50397258
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| Activity |
IC50 = 50700 nM
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[16] | |||
| Compound Name |
(4S)-4-[5-[(Dimethylamino)methyl]-2,4-difluorophenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100140; BDBM50259965
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| Activity |
IC50 = 50900 nM
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[17] | |||
| Compound Name |
2-Amino-3-methyl-6-[2-[3-(1H-pyrrol-2-yl)phenyl]ethyl]pyrimidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL396830; SCHEMBL4146174; BDBM50226444; ZINC28826891; 6-(3-(1H-pyrrol-2-yl)phenethyl)-2-amino-3-methylpyrimidin-4(3H)-one
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| Activity |
IC50 = 51000 nM
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[18] | |||
| Compound Name |
N-[2-[(4Ar,6S)-2-amino-6-methyl-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-8a-yl]-1,3-thiazol-4-yl]-1-methyl-5-(2-methylpropyl)pyrazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3968526; SCHEMBL17162442; BDBM223422; US9315520, 65
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| Activity |
IC50 = 51000 nM
|
[1] | |||
| Compound Name |
Isoliquiritigenin
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Investigative | Compound Info | ||
| Synonyms |
2',4,4'-Trihydroxychalcone; 4,2',4'-Trihydroxychalcone; 6'-deoxychalcone; 2',4',4-Trihydroxychalcone; isoliquirtigenin; UNII-B9CTI9GB8F; C15H12O4; Chalcone, 2',4,4'-trihydroxy-; MFCD00075907; B9CTI9GB8F; 42'4'-trihydroxychalcone; CHEMBL129795; trans-2',4,4'-trihydroxychalcone; GU 17; GU-17; SMR000112969; CCRIS 7676; SR-01000075499; EINECS 237-316-5; BRN 1914295; iso-Liquiritigenin; Isoliquiritigenin/; PubChem21917; Isoliquiritigenin, powder; Spectrum5_000612; Lopac0_000681; BSPBio_003411; 1-08-00-00707 (Beilstein Handbook Reference); MLS000438943; MLS002207240; MLS006010045; BIDD:ER0235; SCHEMBL161168; SPECTRUM1504200; cid_638278; MEGxp0_001326; 2',4,4'-Trihydroxy-Chalcone; DTXSID2022466; 2'',4'',4-trihydroxychalcone; 2'',4,4''-trihydroxychalcone; ACon1_000047; BCPP000201; HMS2233H18; HMS3262I03; 2,4''-dihydroxy-4-hydroxychalcone; BCP02312; HY-N0102; ZINC3869608; Tox21_500681; ABP000708; BDBM50042944; CCG-40334; CI0036; CMLD3_000056; LMPK12120096; s2404; SBB066136; 2',4,4'-Trihydroxychalcone, 97%; Isoliquiritigenin, analytical standard; AKOS001590146; BCP9000795; CS-1745; DB03285; KS-5256; LP00681; MCULE-1557671934; SDCCGMLS-0066751.P001; SDCCGSBI-0050660.P004; NCGC00090504-01; NCGC00090504-02; NCGC00090504-03; NCGC00090504-04; NCGC00090504-05; NCGC00090504-06; NCGC00090504-07; NCGC00090504-08; NCGC00090504-24; NCGC00261366-01; ST081356; AB0000350; EU-0100681; I0822; N1288; SW219658-1; C08650; I 3766; M-1539; 961I295; A845551; NCGC00090504-04!2',4,4'-Trihydroxychalcone; 2',4'-Dihydroxy-3-(p-hydroxyphenyl)-Acrylophenone; Q-100904; Q3155537; SR-01000075499-1; SR-01000075499-5; BRD-K33583600-001-03-9; BRD-K33583600-001-04-7
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| Activity |
IC50 = 51500 nM
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[19] | |||
| Compound Name |
3-N-[(1S,2S)-1-[(2S,5S)-4-Benzyl-5-methyl-3-oxopiperazin-2-yl]-1-hydroxy-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4087083; SCHEMBL12387606
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| Activity |
Ki = 52900 nM
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[20] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[4-(6-methoxypyridin-2-yl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169947; BDBM50397257
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| Activity |
IC50 = 53300 nM
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[16] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[4-(3-propan-2-yloxyphenyl)phenyl]cyclopropyl]pyrimidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2172797; SCHEMBL15427676; BDBM50397251
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| Activity |
IC50 = 54000 nM
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[16] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-[(3-fluorophenyl)methyl]-5-methylhexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221454; BDBM50324934; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(3-fluorobenzyl)-5-methylhexanamide
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| Activity |
IC50 = 54000 nM
|
[21] | |||
| Compound Name |
(4S)-4-[2,4-Difluoro-5-[(3,3,3-trifluoropropylamino)methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084170; BDBM50259955
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| Activity |
IC50 = 54700 nM
|
[17] | |||
| Compound Name |
(3R,4S,5S)-3-(3-Bromo-4-hydroxybenzyl)-5-(3-isopropylbenzylamino)tetrahydro-2H-pyran-4-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760730; BDBM50341183
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| Activity |
IC50 = 55000 nM
|
[22] | |||
| Compound Name |
Byakangelicin
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Investigative | Compound Info | ||
| Synonyms |
Biacangelicin; Bjacangelicin; Bjakangelicin; Byankagelicine; Byacangelicin; Byak-angelicin; UNII-LE80Z850I1; LE80Z850I1; C17H18O7; (+)-Byakangelicin; 9-[(2R)-2,3-dihydroxy-3-methyl-butoxy]-4-methoxy-furo[3,2-g]chromen-7-one; Byakangelicine; 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxyfuro[3,2-g]chromen-7-one; 9-(2,3-Dihydroxy-3-methylbutoxy)-4-methoxy-7H-furo(3,2-g)(1)benzopyran-7-one; MLS000574875; CHEMBL508648; CTK4J0724; DTXSID70197456; Biacangelicin, analytical standard; HMS2194N09; ZINC898098; HY-N6022; 9113AF; BDBM50361390; AKOS032949081; NCGC00247536-01; BS-17100; SMR000156212; CS-0032189; FT-0689305; N2544; A14670; C09141; Q-100528; Q3639306; (R)-9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-7H-furo[3,2-g]chromen-7-one
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| Activity |
Ki = 55000 nM
|
[2] | |||
| Compound Name |
CID 90056449
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703242; SCHEMBL15589567; BDBM149759; US8975415, RP37
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| Activity |
IC50 = 55400 nM
|
[15] | |||
| Compound Name |
FC1(F)COC(N)=NC11C2(CC2)COC2=CC=C(Br)C=C21
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3650844; SCHEMBL15550352; BDBM149935; US8975415, RP216
Click to Show/Hide
|
||||
| Activity |
IC50 = 55800 nM
|
[15] | |||
| Compound Name |
N-(3-((4S,6S)-2-Amino-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl)-4-fluorophenyl)-4-methoxypiperidine-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3908739; SCHEMBL15991081; BDBM214920; US9296734, 119
Click to Show/Hide
|
||||
| Activity |
IC50 = 55800 nM
|
[23] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2R,3S)-1-[[(1S)-1-carboxybutyl]amino]-2-hydroxy-5-methyl-1-oxohexan-3-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604596; BDBM50110910
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[24] | |||
| Compound Name |
4-(2-{2-[4-(2-Biphenyl-4-yl-acetylamino)-3-hydroxy-6-methyl-heptanoylamino]-3-methyl-butyrylamino}-propionylamino)-4-(1-carboxy-2-phenyl-ethylcarbamoyl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300665; BDBM50127405
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[11] | |||
| Compound Name |
[(3S,4R)-4-(2-Bromophenyl)pyrrolidin-3-yl]-(2-phenylpiperidin-1-yl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934287; SCHEMBL3748762; BDBM50360715
Click to Show/Hide
|
||||
| Activity |
IC50 = 57000 nM
|
[25] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-[4-[3-(trifluoromethyl)phenyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322541; BDBM50427053
Click to Show/Hide
|
||||
| Activity |
IC50 = 58900 nM
|
[26] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[4-(furan-2-yl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169944; BDBM50397260
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[16] | |||
| Compound Name |
4-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(cyclohexylmethyl)-N-methylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222140; BDBM50324913; 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)-N-methylbutanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[21] | |||
| Compound Name |
Morusin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Mulberrochromene; TCMDC-124149; UNII-T4VGD5NP9B; NSC649220; T4VGD5NP9B; CHEMBL464006; Morusin, 3; NSC 649220; MLS000697591; MEGxp0_001039; SCHEMBL2562778; ACon1_001205; cid_5281671; DTXSID70211641; HMS2271K05; BCP16494; HY-N0622; ZINC5195808; BDBM50242014; LMPK12110912; MFCD09953814; AKOS032962066; CS-6885; NSC-649220; AK169967; SMR000470930; FT-0686661; N2266; W1523; A14647; C10106; BRD-K40169295-001-01-2; Q27107393
Click to Show/Hide
|
||||
| Activity |
IC50 = 59400 nM
|
[27] | |||
| Compound Name |
6'-Bromodispiro[1,3-oxazole-4,4'-chromene-3',3''-oxetan]-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703206; SCHEMBL15550465; BDBM149716; US8975415, RP2
Click to Show/Hide
|
||||
| Activity |
IC50 = 59600 nM
|
[15] | |||
| Compound Name |
3-[4-[(1R,2S)-2-(2-Amino-1-methyl-6-oxopyrimidin-4-yl)cyclopropyl]phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169924; BDBM50397241
Click to Show/Hide
|
||||
| Activity |
IC50 = 59900 nM
|
[16] | |||
| Compound Name |
N-[3-(5-Amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl)phenyl]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL361261; CHEMBL3653365; BDBM134317; US8846658, 28
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[28] | |||
| Compound Name |
Chembl262454
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370075; BDBM50108558; NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta(S-OH)-D-A-E-F-R
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[29] | |||
| Compound Name |
Norartocarpetin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL463145; 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; 2-(2,4-Dihydroxy-phenyl)-5,7-dihydroxy-1-benzopyran-4-one; 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one; 4H-1-Benzopyran-4-one, 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-; Norartocarpetin, 5; 2-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; SCHEMBL1546435; CTK4J5293; 5,7,2',4'-tetrahydroxyflavone; DTXSID00199963; BDBM50269559; LMPK12110941; AKOS015906501; 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one; Q15425765; 2-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 9CI
Click to Show/Hide
|
||||
| Activity |
IC50 = 60600 nM
|
[27] | |||
| Compound Name |
6'-Bromodispiro[cyclobutane-1,3'-chromene-4',4''-[1,3]oxazol]-2''-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703213; SCHEMBL15589231; BDBM149723; US8975415, RP8
Click to Show/Hide
|
||||
| Activity |
IC50 = 61300 nM
|
[15] | |||
| Compound Name |
Tert-butyl N-[(2S)-1-[[(3S)-1-amino-5-[[(4S,5S,7R)-8-[[(2S)-1-(benzylamino)-1-oxopropan-2-yl]amino]-5-hydroxy-2,7-dimethyl-8-oxooctan-4-yl]amino]-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2299404; BDBM50489055
Click to Show/Hide
|
||||
| Activity |
Ki = 61376.2 nM
|
[14] | |||
| Compound Name |
Xanthotoxol geranyl ether
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
8-geranyloxypsoralen; 8-Geranyloxy psoralen; 8-GERANOPSORALEN; 9-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one; CHEMBL1412710; 9-[(2E)-3,7-dimethylocta-2,6-dienoxy]furo[3,2-g]chromen-7-one; 9-[(3,7-Dimethyl-2,6-octadienyl)oxy]-7H-furo[3,2-g][1]benzopyran-7-one; 9-((2E)-3,7-dimethylocta-2,6-dienyloxy)furano[3,2-g]chromen-2-one; 8-Geranoxypsoralen; 8-geranoxy-psoralen; 9-Geranyloxypsoralen; MLS002472920; SCHEMBL4538668; 8-geranyloxypsoralen, AldrichCPR; HMS2268O12; HY-N2262; ZINC2529828; BDBM50361381; MFCD03412052; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,7-dimethyl-2,6-octadienyl)oxy)-; AKOS016009380; (E)-9-((3,7-Dimethyl-2,6-octadienyl)oxy)-7H-furo(3,2-g)(1)benzopyran-7-one; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)-; 8-Geranyloxypsoralen, analytical standard; NCGC00142593-01; NCGC00142593-02; SMR001397031; ST069304; CS-0019591; W1271; Q3599893; 9-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-furo[3,2-g]chromen-2-one
Click to Show/Hide
|
||||
| Activity |
Ki = 61600 nM
|
[2] | |||
| Compound Name |
4-Acetamido-N-[(2S,3R)-4-[[(2S)-1-(cyclohexylamino)-1-oxopropan-2-yl]amino]-3-hydroxy-1-phenylbutan-2-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271231; BDBM50373801
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[30] | |||
| Compound Name |
(6As,12aR)-11,12a-dihydroxy-4,9-dimethoxy-10-methyl-6,6a-dihydrochromeno[3,4-b]chromen-12-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3287407; BDBM50018960
Click to Show/Hide
|
||||
| Activity |
IC50 = 62210 nM
|
[31] | |||
| Compound Name |
1-N-[(2S,3R)-4-(Cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-3-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-methanesulfonamidobenzene-1,3-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164462; BDBM16408; hydroxyethylamine containing compound 9
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[9] | |||
| Compound Name |
Cruzain-IN-1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ML092; CHEMBL567341; MMV676881; 6-(3,5-difluoroanilino)-9-ethyl-2-purinecarbonitrile; 6-(3,5-difluoroanilino)-9-ethylpurine-2-carbonitrile; 6-(3,5-Difluorophenylamino)-9-ethyl-9H-purine-2-carbonitrile; 6-[(3,5-difluorophenyl)amino]-9-ethyl-9H-purine-2-carbonitrile; Cruzain-IN-1ML092; Cruzain-IN-1;ML-092; ML092 Cruzain-IN-1; MLS002471782; HMS2203P24; HMS3332L09; BCP29960; BDBM50303420; NCGC00181918-01; NCGC00181918-02; BS-14613; HY-10836; ML092;ML 092;ML-092; SMR001395197; CS-0002855; S0722; Q27164166
Click to Show/Hide
|
||||
| Activity |
IC50 = 63095.73 nM
|
[32] | |||
| Compound Name |
N-[[4-(1,3-Dihydroisoindol-2-ylmethyl)phenyl]methyl]-2-(4-phenylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322830; BDBM50427045
Click to Show/Hide
|
||||
| Activity |
IC50 = 63300 nM
|
[26] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-[4-[3,5-bis(trifluoromethyl)phenyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322539; BDBM50427056
Click to Show/Hide
|
||||
| Activity |
IC50 = 63900 nM
|
[26] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-4-[[(1S)-1-carboxybutyl]amino]-1-cyclohexyl-3-hydroxy-4-oxobutan-2-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604597; BDBM50110909
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[24] | |||
| Compound Name |
Phenyl-substituted sulfonamides, 6f
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL510829; BDBM32389
Click to Show/Hide
|
||||
| Activity |
Ki = 64000 nM
|
[33] | |||
| Compound Name |
CID 90246729
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703292; SCHEMBL15831407; BDBM149816; US8975415, RP97; US8975415, RP98
Click to Show/Hide
|
||||
| Activity |
IC50 = 64100 nM
|
[15] | |||
| Compound Name |
US8865911, 47 Isomer 4
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8865911, 47 Isomer 5; US8865911, 47 Isomer 6; US8865911, 47 Isomer 8; SCHEMBL9947938; CHEMBL3653701; BDBM136798; US8865911, 47 Isomer 2; 6-bromo-5'-methyl-2-(oxan-3-yl)spiro[2,3-dihydrochromene-4,2'-imidazole]-4'-amine; 6-Bromo-5'-methyl-2-(tetrahydro-2H-pyran-3-yl)spiro[chroman-4,2'-imidazol]-4'-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 65300 nM
|
[34] | |||
| Compound Name |
(3R,4S,5S)-3-(Benzylamino)-5-[(3-bromo-4-hydroxyphenyl)methyl]-1,1-dioxothian-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760863; BDBM50341179; (3R,4S,5S)-3-Benzylamino-5-(3-bromo-4-hydroxy-benzyl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-ol
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[22] | |||
| Compound Name |
(5R)-2-Amino-5-(2-cyclohexylethyl)-3-methyl-5-[[(3S)-piperidin-3-yl]methyl]imidazol-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3353632; BDBM50036590
Click to Show/Hide
|
||||
| Activity |
Ki = 66000 nM
|
[35] | |||
| Compound Name |
C1OCC(N)=NC21C1(COC1)COC1=CC=C(Br)C=C12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703306; SCHEMBL15589237; BDBM149833; US8975415, RP114
Click to Show/Hide
|
||||
| Activity |
IC50 = 68300 nM
|
[15] | |||
| Compound Name |
N-{2-Methoxy-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461867; BDBM26489
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[36] | |||
| Compound Name |
(S)-N-((1S,2S,4R)-1-Benzyl-2-hydroxy-4-isobutylcarbamoyl-heptyl)-2-(3-methyl-butyrylamino)-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158203; BDBM50139110
Click to Show/Hide
|
||||
| Activity |
Ki = 69500 nM
|
[37] | |||
| Compound Name |
N-[3-[4-[(1R,2S)-2-(2-Amino-1-methyl-6-oxopyrimidin-4-yl)cyclopropyl]phenyl]phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169923; BDBM50397242
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[16] | |||
| Compound Name |
3-(3-Amino-3-benzyl-4-hydroxybutoxy)-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1083498; BDBM50313908
Click to Show/Hide
|
||||
| Activity |
IC50 = 70500 nM
|
[38] | |||
| Compound Name |
(S)-3-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-benzylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222142; BDBM50324915
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[21] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2R,3S)-1-[[(1S)-1-carboxybutyl]amino]-2-hydroxy-5-methylhexan-3-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604698; BDBM50110898
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[24] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[3-(3-fluorophenyl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381676; BDBM50491271
Click to Show/Hide
|
||||
| Activity |
IC50 = 72400 nM
|
[39] | |||
| Compound Name |
US8975415, RP1a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703205; SCHEMBL15551373; BDBM149714; US8975415, RP1b; 6'-bromo-4,5-dihydro-3H-dispiro[furan-2,3'-chromene-4',4''-[1,3]oxazol]-2''-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 73300 nM
|
[15] | |||
| Compound Name |
(4S)-4-[2,4-Difluoro-5-[[(5-methylpyridin-2-yl)amino]methyl]phenyl]-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091480; BDBM50259976
Click to Show/Hide
|
||||
| Activity |
IC50 = 73500 nM
|
[17] | |||
| Compound Name |
6-Chloro-N-[(1S)-1-furo[2,3-d]pyrimidin-2-yl-2-phenylethyl]-3,3-dimethyl-2,4-dihydroisoquinolin-1-imine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346803; BDBM50432172
Click to Show/Hide
|
||||
| Activity |
IC50 = 73700 nM
|
[40] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-(3-methylphenyl)phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381579; SCHEMBL15427638; BDBM50491262
Click to Show/Hide
|
||||
| Activity |
IC50 = 74900 nM
|
[39] | |||
| Compound Name |
(R)-Methyl 2-((S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)pentanamido)-3-tert-butoxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222367; BDBM50324931
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[21] | |||
| Compound Name |
6-Bromo-5'-methylspiro[2,3-dihydro-1H-naphthalene-4,2'-imidazole]-4'-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
US8865911, 51; SCHEMBL9948117; CHEMBL3653709; BDBM136808; US8865911, 239; 7'-Bromo-5-methyl-3',4'-dihydro-2'H-spiro[imidazole-2,1'-naphthalen]-4-amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 75600 nM
|
[34] | |||
| Compound Name |
2-Amino-6-[2-(1H-indol-6-yl)ethyl]-3-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237891; SCHEMBL4145711; BDBM50226443; 2-amino-6-[2-(1H-indol-6-yl)ethyl]-3-methylpyrimidin-4-one; 2-Amino-6-[2-(1H-indol-6-yl)ethyl]-3-methylpyrimidin4(3H)-one; 6-(2-(1H-indol-6-yl)ethyl)-2-amino-3-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[18] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-(3-fluoro-4-phenylphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322535
Click to Show/Hide
|
||||
| Activity |
IC50 = 77100 nM
|
[26] | |||
| Compound Name |
Rac-3-[(3-Butyl-ureidomethyl)benzyl]-5-isobutyl-5-methyl-2-iminohydantoin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL568967; SCHEMBL7516048; BDBM50300231
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[5] | |||
| Compound Name |
2-Amino-6-(3,4-dichlorophenyl)-6-methyl-5,6-dihydro-3H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397162; SCHEMBL4150737; BDBM50226458; 2-amino-4-(3,4-dichlorophenyl)-4-methyl-1,5-dihydropyrimidin-6-one; 2-Amino-6-(3,4-dichloro-phenyl)-6-methyl-5,6-dihydro-3H-pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 79000 nM
|
[18] | |||
| Compound Name |
Chembl4209994
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50452873
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 79300 nM
|
[41] | |||
| Compound Name |
1-Carbazol-9-yl-3-naphthalen-2-ylsulfanylpropan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058870; BDBM50388752
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[12] | |||
| Compound Name |
US8975415, RP12a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703217; SCHEMBL15589217; BDBM149729; US8975415, RP12b
Click to Show/Hide
|
||||
| Activity |
IC50 = 81300 nM
|
[15] | |||
| Compound Name |
(1S,2S,6R,10R,12R,15R,16S)-12-Chloro-6-ethyl-15-hydroxy-6-methyl-17-oxapentacyclo[14.2.1.01,13.02,10.05,9]nonadeca-5(9),13-dien-18-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3937141; BDBM50190652
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[42] | |||
| Compound Name |
Xestosaprol H
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165416; BDBM50321126
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[43] | |||
| Compound Name |
4-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222031; BDBM50324908
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[21] | |||
| Compound Name |
(1-Methoxycarbonylpiperidin-4-yl) (2'R,3S)-2-oxospiro[1H-indole-3,4'-pyrrolidine]-2'-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2181978; BDBM50397737
Click to Show/Hide
|
||||
| Activity |
IC50 = 83700 nM
|
[44] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[3-(6-methoxypyrazin-2-yl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381678; BDBM50491260
Click to Show/Hide
|
||||
| Activity |
IC50 = 84900 nM
|
[39] | |||
| Compound Name |
N-(2-Acetylphenyl)-4-(5-quinolin-1-ium-1-ylpentoxy)benzamide;bromide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159662
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[45] | |||
| Compound Name |
Benzyl (3s,5'r)-2-Oxo-1,2-Dihydrospiro[indole-3,3'-Pyrrolidine]-5'-Carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2181979; BDBM50397736; Q27449922; 09A
Click to Show/Hide
|
||||
| Activity |
IC50 = 85700 nM
|
[44] | |||
| Compound Name |
(2R)-N-[[4-(Aminomethyl)phenyl]methyl]-2-(3-fluoro-4-phenylphenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322536; BDBM50427055
Click to Show/Hide
|
||||
| Activity |
IC50 = 85700 nM
|
[26] | |||
| Compound Name |
2-Amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin-4(3H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL236777; SCHEMBL4139678; BDBM50226445; DB07535; Q27096756; 2-Amino-6-[2-(1H-indol-6-yl)ethyl]pyrimidin4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[18] | |||
| Compound Name |
(S)-2-((S)-3-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)pentanamido)-3-tert-butoxypropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222368; BDBM50324932
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[21] | |||
| Compound Name |
(4Ar,8aS)-8a-[2-(trifluoromethoxy)phenyl]-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL3302831; CHEMBL3691375; BDBM142384; US8933221, 25
Click to Show/Hide
|
||||
| Activity |
IC50 = 87900 nM
|
[46] | |||
| Compound Name |
(4S,5R)-4-(2,4-Difluorophenyl)-5-(methoxymethyl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3414704; BDBM50078350
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[47] | |||
| Compound Name |
{(S)-1-[(S)-1-((2S,4S)-1-Benzyl-2-hydroxy-4-{(R)-2-methyl-1-[(pyridin-4-ylmethyl)-carbamoyl]-propylcarbamoyl}-pentylcarbamoyl)-ethylcarbamoyl]-3-dimethylamino-propyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL81518; BDBM50137689
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[48] | |||
| Compound Name |
Xestosaprol J
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163895; BDBM50321128
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[43] | |||
| Compound Name |
4-Bromo-N-[(4-bromophenyl)sulfonyl]-N-[1-(3,4-dichlorobenzyl)-1H-pyrazol-4-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782316; AK-968/41924275; ZINC8455492; BDBM50346132; STK450112; AKOS003288845; MCULE-6311714379; ST50832214; bis[(4-bromophenyl)sulfonyl]{1-[(3,4-dichlorophenyl)methyl]pyrazol-4-yl}amine
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[3] | |||
| Compound Name |
2-Amino-6-[3-(3-methoxyphenyl)phenyl]-3,6-dimethyl-5H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL392662; SCHEMBL4141578; BDBM50226442; 2-amino-6-(3''-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydro-3H-pyrimidin-4-one; 2-Amino-6-(3'-methoxy-biphenyl-3-yl)-3,6-dimethyl-5,6-dihydro-3H-pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[18] | |||
| Compound Name |
2-Amino-6-[2-[3-(3-methoxyphenyl)phenyl]ethyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235754; SCHEMBL4136983; BDBM50226453; 2-amino-6-[2-(3''-methoxy-1,1''-biphenyl-3-yl)ethyl]-3-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[18] | |||
| Compound Name |
3-[((S)-2-{(3S,4S)-4-[(R)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-propionylamino]-3-hydroxy-6-methyl-heptanoylamino}-3-methyl-butyrylamino)-methyl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL334591; BDBM50136327
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
(S)-4-Amino-4-((S)-1-{(S)-2-carbamoyl-1-[(S)-1-((S)-2-carbamoyl-1-hydroxy-ethyl)-3-methyl-butylcarbamoyl]-ethylcarbamoyl}-2-methyl-propylcarbamoyl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341944; BDBM50136332
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
(S)-4-((S)-2-{(S)-2-[(3S,4S)-4-((S)-2-Amino-3-carbamoyl-propionylamino)-3-hydroxy-6-methyl-heptanoylamino]-3-methyl-butyrylamino}-propionylamino)-4-((S)-1-carboxy-2-phenyl-ethylcarbamoyl)-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL137131; BDBM50136335
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
3-[((R)-2-{(3S,4S)-4-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-4-methylsulfanyl-butyrylamino]-3-hydroxy-6-methyl-heptanoylamino}-3-methyl-butyrylamino)-methyl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL343563; BDBM50136354
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
3-[((S)-2-{(3S,4S)-4-[(R)-2-((S)-2-Acetylamino-4-methyl-pentanoylamino)-4-methylsulfanyl-butyrylamino]-3-hydroxy-6-methyl-heptanoylamino}-3-methyl-butyrylamino)-methyl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185920; BDBM50136349
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
3-[[[(2S)-2-[[(3S,4S)-4-[[(2S)-2-[[(2R,3R)-2-Acetamido-3-methylpentanoyl]amino]propanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]methyl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1791019; BDBM50366845
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91000 nM
|
[49] | |||
| Compound Name |
Xestosaprol K
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163540; BDBM50321129
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[43] | |||
| Compound Name |
4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{3-hydroxy-6-methyl-4-[2-(3,4,5-trimethoxy-phenyl)-acetylamino]-heptanoylamino}-3-methyl-butyrylamino)-propionylamino]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL301944; BDBM50127413
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[11] | |||
| Compound Name |
6-[2-(1H-Indol-6-yl)ethyl]pyridin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-[2-(1H-indol-6-yl)-ethyl]-pyridin-2-ylamine; CHEMBL221118; SCHEMBL4938783; BDBM15779; 6-Substituted 2-Aminopyridine 3; DB07206; Q27096127
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[50] | |||
| Compound Name |
[1-(1-{1-[1-Hydroxy-2-(1-hydroxycarbamoyl-2-methyl-propylcarbamoyl)-ethyl]-3-methyl-butylcarbamoyl}-3-methylsulfanyl-propylcarbamoyl)-2-methyl-propyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL50827; BDBM50127411
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[11] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(3,3-dimethylbutyl)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222301; BDBM50324927; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(3,3-dimethylbutyl)pentanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[21] | |||
| Compound Name |
C1=CC2=NC(C)=CN2C=C1C(C=C1C2(N=C(N)OC2)C23Coc3)=CC=C1OC12ccc1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3640021; SCHEMBL15538431; BDBM149786; US8975415, RP67
Click to Show/Hide
|
||||
| Activity |
IC50 = 96500 nM
|
[15] | |||
| Compound Name |
Xestosaprol L
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163545; BDBM50321130
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[43] | |||
| Compound Name |
(5R,7S)-1-(3-Fluorophenyl)-8-[(3-methoxyphenyl)methyl]-7-methyl-2lambda6-thia-1,3,8-triazaspiro[4.5]decane 2,2-dioxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2177486; SCHEMBL1170453; BDBM50398631
Click to Show/Hide
|
||||
| Activity |
IC50 = 99300 nM
|
[51] | |||
| Compound Name |
N,N''-(2-Hydroxypropane-1,3-diyl)bis(2-benzamidobenzamide)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164743; BDBM50320684; ZINC49807432; AKOS024370305; MCULE-8070553135; ST51005838
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-(Benzylsulfanyl)-6-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6,7-dihydro[1,2,4]triazino[5,6-d][3,1]benzoxazepine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782313; AN-655/13300055; BDBM50346129; STL445135; AKOS000357395; AKOS021673477; MCULE-6822756624
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[3] | |||
| Compound Name |
N-[(2S)-5-(Diaminomethylideneamino)-1-[[(2S)-1-[[(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-(2-phenylethylamino)heptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]benzamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344268
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
3-[(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]-N-(4-fluorobenzyl)-4-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164406; BDBM50320637; AKOS001587903; MCULE-6485307149; SR-01000583880; SR-01000583880-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-{[(5-Aminopentyl)carbamoyl]methoxy}-5-{[(1R)-1-phenylethyl]carbamoyl}phenyl 1-phenylmethanesulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
oxyacetamide 3; CHEMBL374512; BDBM16044
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
3-(4-Chlorobenzyl)-N-((1-ethylpyrrolidin-2-yl)methyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164095; BDBM50320643; AKOS002075688; MCULE-4800010082; EU-0061697; SR-01000563039; SR-01000563039-1; F0916-6333
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(3S,4S)-1-(2,3-dihydro-1H-inden-2-ylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344264
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-(4-Chlorobenzyl)-3-[(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]-4-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163251; BDBM50320635; AKOS001588033; MCULE-7184900435; EU-0096847; SR-01000583475; SR-01000583475-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-(3-Amino-3-benzyl-4-hydroxybutyl)sulfonyl-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1083529; BDBM50313905
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
(3R,4S,5S)-3-Amino-5-[(3-bromo-4-hydroxyphenyl)methyl]-1,1-dioxothian-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760862; BDBM50341178; (3R,4S,5S)-3-Amino-5-(3-bromo-4-hydroxy-benzyl)-1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
N-(4-Iodophenyl)-6-methoxy-N'-(2-morpholin-4-ylethyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163707; HMS1647D08; BDBM50320619; ZINC20757246; AKOS002111158; MCULE-4464596575; SR-01000590608; SR-01000590608-1; N2-(4-iodophenyl)-6-methoxy-N4-(2-morpholinoethyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
2-(5-((1H-Indol-3-yl)methyl)-4-benzyl-4H-1,2,4-triazol-3-ylthio)-1-(1H-indol-3-yl)ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782315; ZINC721922; BDBM50346131; AKOS002124078; MCULE-2017284421; EU-0031900; 2-{[4-benzyl-5-(1H-indol-3-ylmethyl)-4H-1,2,4-triazol-3-yl]thio}-1-(1H-indol-3-yl)ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[3] | |||
| Compound Name |
6-Chloro-N2-(4-iodobenzyl)-N4-(2-morpholinoethyl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163699; BDBM50320616
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Tert-butyl N-benzyl-N-[(2S)-2-hydroxy-2-[3-[[(2R)-2-phenyl-2-(phenylmethoxycarbonylamino)acetyl]amino]phenyl]ethyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3086246; BDBM50494389
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[54] | |||
| Compound Name |
N-{2-[(Heptafluoropropyl)sulfanyl]phenyl}-2-(3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164362; BDBM50320647; STL020165; AKOS002256565; AKOS016318926; MCULE-9591814791; ST50455615
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344166; BDBM50099380
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
2-Benzyl-3-hydroxy-2-(methylamino)propyl 3-((R)-1-(4-fluorophenyl)ethylcarbamoyl)-5-(N-methylmethylsulfonamido)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086647; SCHEMBL8299165; BDBM50313893
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-phenyl-2-(thiophene-2-sulfonamido)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164238; BDBM50320675; MCULE-6057960242; N-[4-chloro-3-(trifluoromethyl)phenyl]-2-phenyl-2-[(thien-2-ylsulfonyl)amino]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(4As,6S,8aR)-6-cyclopropyl-8a-(2,4-difluorophenyl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3897712; SCHEMBL15839815; BDBM238985; US9403846, C23
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[55] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-5-(Diaminomethylideneamino)-2-[(2-phenylmethoxyacetyl)amino]pentanoyl]amino]propanoyl]amino]-3-hydroxy-6-methyl-N-(2-phenylethyl)heptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344269
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N''-(3-Ethoxy-4-hydroxy-5-iodobenzylidene)-2-(p-tolyloxy)acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164435; ZINC1092641; BDBM50320688; AKOS024281870; ST048993; N-[(1Z)-2-(5-ethoxy-4-hydroxy-3-iodophenyl)-1-azavinyl]-2-(4-methylphenoxy)ace tamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-4-phenylbutan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344159; BDBM50099242
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
(4Ar,8aS)-8a-(2-methoxyphenyl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3691371; SCHEMBL14716479; BDBM142378; US8933221, 19
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
8-Benzyl-4-cyclohexylimino-1-(3,3-dimethylbutyl)-1,3,8-triazaspiro[4.5]decan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521824
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
3-[[(2-Hexyl-4-oxoquinazolin-3-yl)amino]-hydroxymethyl]-4-hydroxy-1-azatricyclo[7.3.1.05,13]trideca-3,5,7,9(13)-tetraen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165526; BDBM50320644
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-Acetamido-N-(3-chloro-5-fluorobenzyl)-4-(4-chlorophenylthio)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163953; BDBM50320655
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Ethyl 2-(9,10-dioxo-9,10-dihydroanthracene-2-sulfonamido)-3-(4-hydroxyphenyl)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165064; ChemDiv1_017696; HMS637E08; BDBM50320669; STK673145; AKOS005593064; MCULE-6056742152; ST046926; ethyl N-[(9,10-dioxo-9,10-dihydroanthracen-2-yl)sulfonyl]tyrosinate; ethyl 2-{[(9,10-dioxo(2-anthryl))sulfonyl]amino}-3-(4-hydroxyphenyl)propanoate
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(4-(Aminosulfonyl)phenyl)-2-((5,6-diphenyl-1,2,4-triazin-3-YL)thio)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165057; ChemDiv1_023200; HMS652O12; ZINC2064221; BDBM50320667; AKOS001626043; MCULE-4065035079; SR-01000452605; SR-01000452605-1; 2-((5,6-Diphenyl-1,2,4-triazin-3-yl)thio)-N-(4-sulfamoylphenyl)acetamide; 2-(5,6-diphenyl-1,2,4-triazin-3-ylthio)-N-(4-sulfamoylphenyl)acetamide; 2-(5,6-Diphenyl-[1,2,4]triazin-3-ylsulfanyl)-N-(4-sulfamoyl-phenyl)-acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-[(2-Amino-2-benzyl-3-methoxypropoxy)methyl]-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1090060; BDBM50313904
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-(2-hydroxy-4-phenylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322533; BDBM50427052
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-[2-(4-chlorophenyl)ethylamino]-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344266
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
6-Methyl-2-oxo-N-[6-(1,2,3,4-tetrahydroacridin-9-ylamino)hexyl]chromene-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3326707; BDBM50056108
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[57] | |||
| Compound Name |
(2S)-2-[[(3S,4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]pentanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344151; BDBM50099148
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-{2-[4-(Aminosulfonyl)phenyl]ethyl}-3-(4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165270; ChemDiv2_005917; MLS001160758; HMS1385M21; HMS3003O13; ZINC4790650; BDBM50320653; AKOS001459238; MCULE-2249163009; IDI1_004632; SMR000715227
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
8-Benzyl-4-(cyclohexylamino)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493274; BDBM25354; Spiropiperidine Iminohydantoin, 9
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
Benzyl N-[(2S)-6-amino-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]carbamate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344156; BDBM50099239
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
Benzyl N-[(2S)-5-amino-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamate;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344155; BDBM50099238
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
Triethyl-[[4-[[[2-(4-phenylphenyl)acetyl]amino]methyl]phenyl]methyl]azanium
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322832; BDBM50427047
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
N-(4-Chlorophenyl)-2-(2,5-dimethoxyphenylimino)-5-(hydroxymethyl)-8-methyl-2H-pyrano[2,3-c]pyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164972; BDBM50320666; ZINC20617133; AKOS002095446; MCULE-7039688422
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[4-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327545; BDBM50108554
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
5-Substituted isophthalamide, 3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL264296; BDBM16717
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[3-[2-(3-methoxyphenyl)ethyl]phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381576; SCHEMBL15427677; BDBM50491267
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[39] | |||
| Compound Name |
2-{[4-Oxo-3-(prop-2-en-1-yl)-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]sulfanyl}-N-(4-sulfamoylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517746; ChemDiv1_002717; Oprea1_230648; HMS594L11; ZINC1811348; BDBM50247722; STK899101; AKOS001010951; MCULE-6139270266; ST50052463; Z20215696
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-[(4-Anilino-6-piperidin-1-yl-1,3,5-triazin-2-yl)amino]-2-(4-chlorophenyl)-1,3-thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165731; ChemDiv3_003369; Oprea1_856395; HMS1482J03; BDBM50320617; STL420604; AKOS000413051; AKOS022001103; MCULE-1314430343; IDI1_021279; SR-01000495336; SR-01000495336-1; BRD-A86500514-001-01-0
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(4R,4As,6S,8aR)-6-cyclopropyl-8a-(2,4-difluorophenyl)-4-(fluoromethyl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3898198; SCHEMBL15839978; BDBM238990; US9403846, C48
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[55] | |||
| Compound Name |
N-(2-(2-Methylpiperidin-1-yl)ethyl)-6-(morpholinosulfonyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165356; SCHEMBL8311334; BDBM50320657
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344164; BDBM50099272
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-[2-(4-Chlorophenyl)ethyl]-4-{[(2-thioxo-1,2-dihydroquinazolin-4-yl)amino]methyl}cyclohexanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165197; MLS000621983; cid_4112670; HMS2724D20; BDBM50320660; ZINC13496846; AKOS002084440; SMR000310910; F6548-4758
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
4-((6,7-Dimethoxy-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)-N-(4-methylbenzyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165202; HMS1814M19; ZINC8592176; BDBM50320664; MCULE-7321175503; NCGC00105069-01; EU-0089831; C191-0209; 4-[(6,7-dimethoxy-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)methyl]-N-(4-methylbenzyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-N-cyclohexyl-3-hydroxy-6-methylheptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344154; BDBM50099237
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
3,3''-(Piperazine-1,4-diylbis(methylene))dibiphenyl-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163649; Oprea1_371336; BDBM50320670
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
6-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)-N-(2-(dimethylamino)ethyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165815; BDBM50320662; SR-01000574769; SR-01000574769-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
2-Ethyl-2-(3-pyrimidin-5-ylphenyl)-1,3-benzoxazin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380439; BDBM50491221
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[59] | |||
| Compound Name |
4-({(S)-2-[(2S,4S)-4-((3S,4S)-4-Tert-Butoxycarbonylamino-3-hydroxy-5-phenyl-pentanoylamino)-5-cyclohexyl-3-hydroxy-pentanoylamino]-3-methyl-butyrylamino}-methyl)-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL326488; BDBM50148339
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
6-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)-4-oxo-N-phenethyl-1,4-dihydroquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164697; Oprea1_335224; BDBM50320656; SR-01000576435; SR-01000576435-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344157; BDBM50099240
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-Benzyl-N'-{4-[chloro(difluoro)methoxy]phenyl}-6-(piperidin-1-yl)-1,3,5-triazine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163660; ZINC2192063; BDBM50320625; STK766181; AKOS001749896; MCULE-5868364271; ST049979
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
6-(N-Methyl-N-m-tolylsulfamoyl)-N-(2-morpholinoethyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163703; BDBM50320674; SR-01000593709; SR-01000593709-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
1,4-Di(carbazol-9-yl)butan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059103; BDBM50388760
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-[4-(4-hydroxyphenyl)phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322542; BDBM50427050
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
1,8-Dibenzyl-4-(cyclohexylamino)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493474; BDBM25356; Spiropiperidine Iminohydantoin, 11
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
N-{3-[(4-Butylphenyl)amino]quinoxalin-2-yl}-4-chlorobenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165814; Oprea1_611850; SCHEMBL1788517; N-[3-(4-butylanilino)quinoxalin-2-yl]-4-chlorobenzenesulfonamide; ZINC9554131; BDBM50320665; STK064802; AKOS000430392; MCULE-8260283220; SR-01000486433; SR-01000486433-1; N-(3-(4-butylphenylamino)quinoxalin-2-yl)-4-chlorobenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(4-Chlorophenethyl)-4-((6-morpholino-4-oxo-2-thioxo-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164464; ZINC2976101; BDBM50320650; AKOS002096918; MCULE-2087374113; EU-0061469; F6548-4175
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxy-6-methyl-N-(2-phenylethyl)heptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344272
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
2-(2-(2-(8-Methyl-2-oxo-4-propyl-2H-chromen-7-yloxy)acetamido)acetamido)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165549; ZINC2146550; BDBM50320640; EiM07-17341; STL461029; AKOS016390229; MCULE-1838197426; N-{[(8-methyl-2-oxo-4-propyl-2H-chromen-7-yl)oxy]acetyl}glycylglycine
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(4As,8aR)-8a-(2,4-difluorophenyl)-4a,5,6,8-tetrahydro-4H-pyrano[3,4-d][1,3]thiazin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3691372; SCHEMBL14733567; BDBM142379; US8933221, 20
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
(1-{1-[1-(1-Hydroxy-2-{2-methyl-1-[(pyridin-4-ylmethyl)-carbamoyl]-propylcarbamoyl}-ethyl)-3-methyl-butylcarbamoyl]-3-methylsulfanyl-propylcarbamoyl}-2-methyl-propyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299351; BDBM50127412
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
(1-{1-[1-(2-{1-[(Benzo[1,3]dioxol-5-ylmethyl)-carbamoyl]-2-methyl-propylcarbamoyl}-1-hydroxy-ethyl)-3-methyl-butylcarbamoyl]-3-methylsulfanyl-propylcarbamoyl}-2-methyl-propyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL50313; BDBM50127423
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
2-(6-Bromo-2-(morpholinomethyl)-4-phenylquinazolin-3(4H)-yl)acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165812; CBMicro_034147; MLS000692752; HMS2627K13; BDBM50320661; STK862271; AKOS000669088; AKOS021987088; MCULE-1203439504; SMR000285169; ST056842; BIM-0034126.P001; SR-01000416563; SR-01000416563-1; 2-[6-bromo-2-(morpholin-4-ylmethyl)-4-phenylquinazolin-3(4H)-yl]acetohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
2-Methyl-5-propan-2-yl-2-(3-pyridin-3-ylphenyl)imidazol-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2180017; BDBM50398784
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
2-(4-Benzylpiperazin-1-yl)-N''-(2-hydroxy-3,5-diiodobenzylidene)acetohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164096; BDBM50320646; ZINC33358661
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
4-({(S)-2-[(2S,4S)-4-((3S,4S)-4-Amino-3-hydroxy-5-phenyl-pentanoylamino)-5-cyclohexyl-3-hydroxy-pentanoylamino]-3-methyl-butyrylamino}-methyl)-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL332713; BDBM50148342
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
3-(4-Chlorobenzyl)-N-(2-(4-ethylpiperazin-1-yl)ethyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163648; ChemDiv1_013368; HMS624P14; BDBM50320671; ZINC20644056; AKOS002093525; MCULE-8439599814; SR-01000558713; SR-01000558713-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-{[(5-Aminopentyl)carbamoyl]methoxy}-5-{[(1S)-1-phenylethyl]carbamoyl}phenyl 1-phenylmethanesulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
oxyacetamide 4; CHEMBL1164642; BDBM16045
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Chembl327385
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370096; BDBM50108545
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
N-[5-(2,3-Dichlorobenzyl)-1,3-thiazol-2-yl]-4-({[4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]sulfanyl}methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782309; ZINC8399839; BDBM50346124; AKOS002219050; MCULE-9455037056; ST50108194; AP-845/41780025
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-Benzyl-6-bromo-3-(4-ethylphenyl)-4-hydroxy-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164841; BDBM50320645; MCULE-3311658634; EU-0055056
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(2-Acetylphenyl)-4-(5-isoquinolin-2-ium-2-ylpentoxy)benzamide;bromide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159660
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
6-(4-Methylpiperidin-1-ylsulfonyl)-2-oxo-N-(3-(pyrrolidin-1-yl)propyl)-1,2-dihydroquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164127; ZINC8662024; BDBM50320654; MCULE-5260603612; EU-0063904
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(2-(2-Methylpiperidin-1-yl)ethyl)-2-oxo-6-(piperidin-1-ylsulfonyl)-1,2-dihydroquinoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164610; BDBM50320652; EU-0030698
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-N-(4-amino-4-oxobutyl)-3-hydroxy-6-methylheptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344153; BDBM50099236
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
2-(4-Phenylphenyl)-N-[[4-(pyrrolidin-1-ylmethyl)phenyl]methyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322829; BDBM50427049
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
4-Cyclohexylimino-1-(3-fluorophenyl)-1,3,8-triazaspiro[4.5]decan-2-one;dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL592557; CHEMBL1203968
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
N-[[4-(Diethylaminomethyl)phenyl]methyl]-2-(4-phenylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322831; BDBM50427048
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
N-(2-Benzoyl-4-chlorophenyl)-4-[(6-bromo-4-phenylquinazolin-2-yl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163218; BDBM50320677; ZINC58609729; AKOS001266188; MCULE-6553535169; ST51023091; SR-01000427208; SR-01000427208-1; N-(2-benzoyl-4-chlorophenyl)-4-(6-bromo-4-phenylquinazolin-2-ylamino)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
6-Bromo-3-(4-ethylphenyl)-4-hydroxy-N-(2-methyl-3-(4-methylpiperidin-1-yl)propyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165280; BDBM50320663; MCULE-1344599767
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
3-(3-Bromobenzyl)-N-((1-ethylpyrrolidin-2-yl)methyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164837; ChemDiv1_012413; HMS622E05; BDBM50320649; MCULE-3812167285; EU-0053764; SR-01000541904; SR-01000541904-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Hydroxyamphetamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(2-Aminopropyl)phenol; Paredrine; 4-Hydroxyamphetamine; Hydroxyamfetamine; Norpholedrine; Oxamphetamine; p-HYDROXYAMPHETAMINE; Norveritol; Oksamfetamin; Oxamfetamin; Oxamphetaminium; Paredrinex; Pulsoton; Nov-Pholedrin; Paradrine; Pedrolon; p-(2-Aminopropyl)phenol; Phenol, 4-(2-aminopropyl)-; Hydroxyamphetamide; 1-p-Hydroxyphenyl-2-propylamine; 2-Amino-1-(p-hydroxyphenyl)propane; Phenol,4-(2-aminopropyl)-; Phenol, p-(2-aminopropyl)-; .alpha.-Methyltyramine; alpha-Methyltyramine; NSC 170995; DL-p-Hydroxyamphetamine; (RS)-4-hydroxyamphetamine; DL-p-(2-Aminopropyl)phenol; 4-Hydroxy-.alpha.-methylphenethylamine; p-Hydroxy-.alpha.-methylphenethylamine; p-Hydroxy-alpha-methylphenethylamine; 4-Hydroxy-alpha-methylphenethylamine; UNII-FQR280JW2N; EINECS 203-152-8; BRN 2413849; Hydroxyamfetamine [INN:BAN]; FQR280JW2N; Predrolon (Salt/Mix); dl-4-hydroxyamphetamine; Spectrum_001243; Spectrum3_001037; Spectrum4_001174; Spectrum5_001674; Hydroxyamphetamine,(+/-); WLN: Z3R DQ; CHEMBL1546; 4-(2-amino-propyl)-phenol; BSPBio_002853; KBioGR_001807; KBioSS_001723; 3-13-00-01709 (Beilstein Handbook Reference); SCHEMBL125440; DTXSID3023134; BDBM81459; CTK4A2457; KBio2_001723; KBio2_004291; KBio2_006859; KBio3_002073; HY-B1098; NSC_3651; 1-(4-Hydroxyphenyl)propane-2-amine; NSC170995; PDSP1_001107; PDSP2_001091; AKOS000155358; AKOS017269170; CS-4687; DB09352; MCULE-6999513658; NE22868; NSC-170995; Phenol, 4-(2-aminopropyl)- (9CI); NCGC00178433-01; NCGC00178433-02; BS-13447; SC-12990; Phenol, p-(2-aminopropyl)-, (.+/-.)-; EN300-53926; Phenol, 4-(2-aminopropyl)-, (.+/-.)-; AB01563354_01; Q5955531; BRD-A80871782-004-01-0; Z57102382
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
N-Benzyl-4-oxo-6-(N-(2-oxoazepan-3-yl)sulfamoyl)-1,4-dihydroquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164363; BDBM50320648
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-[2-(4-chlorophenyl)ethyl-methylamino]-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344267
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
(2S)-2-[[4-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]-3-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89438; BDBM50108552
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[29] | |||
| Compound Name |
3-[(3-Amino-3-benzyl-4-hydroxybutyl)amino]-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1089043; BDBM50313907
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-(Benzenesulfonamido)-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-3-hydroxy-6-methyl-N-(2-phenylethyl)heptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344270
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-3-hydroxy-6-methyl-N-(2-phenylethyl)heptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344271
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
3-(3-Chloro-4-methoxyphenyl)-N-(2-(6-methylpyridin-2-ylamino)-2-oxoethyl)-4-oxo-3,4-dihydrophthalazine-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165196; BDBM50320659; EU-0054046; SR-01000544632; SR-01000544632-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(2-Chlorobenzyl)-3-[(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]-4-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163250; BDBM50320633; AKOS001588034; MCULE-6943854428; EU-0096857; SR-01000583476; SR-01000583476-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-(2-phenylethylamino)heptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344263
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
3-[(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]-N-(4-methylbenzyl)-4-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164306; BDBM50320634; AKOS002112884; MCULE-6277389707; EU-0030269; SR-01000583882; SR-01000583882-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(benzylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344262
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
4-(Cyclohexylamino)-1-(3-fluorophenyl)-8-(4-fluorophenyl)-1,3,8-triazaspiro[4.5]dec-3-en-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495086; BDBM25360; Spiropiperidine Iminohydantoin, 15
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
Benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-(1-phenylethylamino)heptan-4-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344265
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
Benzyl 3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxo-4-[[1-oxo-1-[(2-oxo-2-phenylmethoxyethyl)amino]-3-phenylmethoxypropan-2-yl]amino]butanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163234; BDBM50320687
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-(3-hydroxy-4-phenylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322534; BDBM50427051
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344261; BDBM50099381
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-Benzyl-3-[(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)amino]-4-(8-oxo-1,5,6,8-tetrahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(4H)-yl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164405; BDBM50320636; AKOS002112883; MCULE-6383684689; EU-0030259; SR-01000583881; SR-01000583881-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
N-(2-Acetylphenyl)-4-(6-isoquinolin-2-ium-2-ylhexoxy)benzamide;bromide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159661
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
(3S,4S)-4-[[(2S)-2-[[(2S)-2-Acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-N-[(2S)-1-amino-1-oxopropan-2-yl]-3-hydroxy-6-methylheptanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344152
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
(4S)-4-[[(2S)-2-[[(2S,3S)-2-[[4-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]-5-[[(1S)-1-carboxy-2-phenylethyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790741; BDBM50370144
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[29] | |||
| Compound Name |
3-(3-Amino-3-benzyl-4-hydroxybutyl)sulfanyl-N-[(1R)-1-(4-fluorophenyl)ethyl]-5-[methyl(methylsulfonyl)amino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1092153; BDBM50313906
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[38] | |||
| Compound Name |
1-(4-Chlorophenyl)-N-(1,3-dihydroxy-1-(4-(methylthio)phenyl)propan-2-yl)-7,7-dimethyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163651; Oprea1_258152; BDBM50320672; MCULE-7139027685
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[9] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S,3S)-1-[[(3S,4S)-1-(cyclohexylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3344165; BDBM50099378
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[52] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-[4-(2,3,4,5,6-pentafluorophenyl)phenyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322540; BDBM50427054
Click to Show/Hide
|
||||
| Activity |
IC50 = 101000 nM
|
[26] | |||
| Compound Name |
Cyclomorusin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cyclomorusin A; Cyclomulberrochromene; CHEMBL1770313; C25H22O6; Cycolmorusin, 2; DTXSID30978167; 9175AF; BDBM50343137; LMPK12110913; AKOS032948896; C17867
Click to Show/Hide
|
||||
| Activity |
IC50 = 101200 nM
|
[27] | |||
| Compound Name |
9-Hydroxy-4-(3,7-dimethyl-2,6-octadienyloxy)-psoralen
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934195; 5-Geranyloxy-8-methoxypsoralen; 5-Geranyloxy-8-methoxy-psoralen; BDBM50361388; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-(((2E)-3,7-dimethyl-2,6-octadienyl)oxy)-9-methoxy-; 4-[[(2E)-3,7-Dimethyl-2,6-octadienyl]oxy]-9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 5-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-9-methoxy-2H-furo[3,2-g]chromen-2-one
Click to Show/Hide
|
||||
| Activity |
Ki = 102700 nM
|
[2] | |||
| Compound Name |
2-Amino-6-[(1R,2S)-2-[3-(3-methoxyphenyl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169936; BDBM50397268
Click to Show/Hide
|
||||
| Activity |
IC50 = 103000 nM
|
[16] | |||
| Compound Name |
Mormin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1770315; BDBM50343139
Click to Show/Hide
|
||||
| Activity |
IC50 = 103500 nM
|
[27] | |||
| Compound Name |
Xestosaprol M
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163828; BDBM50321131
Click to Show/Hide
|
||||
| Activity |
IC50 = 104000 nM
|
[43] | |||
| Compound Name |
Byakangelicol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934196; 9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]-4-methoxyfuro[3,2-g]chromen-7-one; (R)-9-((3,3-Dimethyl-2-oxiranyl)methoxy)-4-methoxyfuro(3,2-g)chromen-7-one; Biacangelicol; DTXSID70180727; 9-[(3,3-Dimethyl-2-oxiranyl)methoxy]-4-methoxy-7H-furo[3,2-g]chromen-7-one #; HY-N0074; 9114AF; BDBM50361389; MFCD06796689; ZINC13380841; AKOS037514577; BS-16330; CS-0007116; N2545; C16925; Q-100330; Q27149843
Click to Show/Hide
|
||||
| Activity |
IC50 = 104900 nM
|
[2] | |||
| Compound Name |
Chembl4170012
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50450090
Click to Show/Hide
|
||||
| Activity |
IC50 = 106700 nM
|
[63] | |||
| Compound Name |
N-{2-Fluoro-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461866; BDBM26488
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[36] | |||
| Compound Name |
Tetrahydro-2h-Pyran-4-Yl (3s,5'r)-2-Oxo-1,2-Dihydrospiro[indole-3,3'-Pyrrolidine]-5'-Carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2181998; BDBM50397738; Q27449919
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[44] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[4-(2-methoxypyridin-4-yl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169916; SCHEMBL15427647; BDBM50397256
Click to Show/Hide
|
||||
| Activity |
IC50 = 116000 nM
|
[16] | |||
| Compound Name |
N-(1-Adamantyl)-2-{[3-cyano-4-(4-fluorophenyl)-6-phenyl-2-pyridinyl]sulfanyl}acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1782311; ZINC8448580; BDBM50346126; STK755377; AKOS001714592; MCULE-6398887707; AK-777/36504051
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[3] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[4-(4-methylphenyl)phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169940; BDBM50397264
Click to Show/Hide
|
||||
| Activity |
IC50 = 119000 nM
|
[16] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-[2-(2-methylphenyl)ethyl]phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381573; BDBM50491276
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[39] | |||
| Compound Name |
N-[3-(5-Amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl)phenyl]cyclohexanecarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1910516; CHEMBL3653362; BDBM134314; US8846658, 25
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 130000 nM
|
[28] | |||
| Compound Name |
4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-{2-[2-(3-hydroxy-6-methyl-4-phenylacetylamino-heptanoylamino)-3-methyl-butyrylamino]-propionylamino}-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298126; BDBM50127406
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[11] | |||
| Compound Name |
N-[3-(5-Amino-3-methyl-2,6-dihydro-1,4-oxazin-3-yl)phenyl]-4,4-difluorocyclohexane-1-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL6936794; CHEMBL3653363; BDBM134315; US8846658, 26
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 130000 nM
|
[28] | |||
| Compound Name |
2-Amino-4-[2-(1H-indol-5-yl)ethyl]-1H-pyrimidin-6-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2172792; BDBM50397279
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[16] | |||
| Compound Name |
(6S)-2-Amino-3,6-dimethyl-6-[(1S,2S)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437449; BDBM50493646
Click to Show/Hide
|
||||
| Activity |
IC50 = 132000 nM
|
[64] | |||
| Compound Name |
Xestosaprol F
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164756; BDBM50321124
Click to Show/Hide
|
||||
| Activity |
IC50 = 135000 nM
|
[43] | |||
| Compound Name |
CID 90056473
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3703267; SCHEMBL15589592; BDBM149785; US8975415, RP66
Click to Show/Hide
|
||||
| Activity |
IC50 = 135000 nM
|
[15] | |||
| Compound Name |
Morusinol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oxydihydromorusin; Oxydihydromorusi; UNII-IA6I4SG21V; IA6I4SG21V; CHEMBL1719948; Oxyhydromorusin; MLS000697725; SCHEMBL5918073; DTXSID80212149; HMS2267M17; HY-N2299; BDBM50343138; LMPK12110919; ZINC13125764; AKOS032948831; NCGC00247530-01; SMR000470983; CS-0019626; FT-0775771; C17868
Click to Show/Hide
|
||||
| Activity |
IC50 = 135900 nM
|
[27] | |||
| Compound Name |
trans-2-Phenylvinylboronic acid MIDA ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2315715; DTXSID70746266; BDBM50424415; ZINC170161634; J3.594.440K; trans-2-Phenylvinylboronic acid MIDA ester, 95%; 6-Methyl-2-styryl-1,3-dioxa-6-aza-2-boracyclooctane-4,8-dione; 6-Methyl-2-[(E)-2-phenylethenyl]-1,3,6,2-dioxazaborocane-4,8-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 136150 nM
|
[65] | |||
| Compound Name |
6-Chloro-3,3-dimethyl-N-(2-phenyl-1-pyrimidin-2-ylethyl)-2,4-dihydroisoquinolin-1-imine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346794; BDBM50432181
Click to Show/Hide
|
||||
| Activity |
IC50 = 137100 nM
|
[40] | |||
| Compound Name |
N-[(2S,3R)-4-[[1-(4-Tert-butyl-1,3-oxazol-2-yl)cyclohexyl]amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1258803; BDBM50328044
Click to Show/Hide
|
||||
| Activity |
IC50 = 137800 nM
|
[66] | |||
| Compound Name |
4-(1-Carboxy-2-phenyl-ethylcarbamoyl)-4-[2-(2-{4-[2-(2,4-difluoro-phenyl)-acetylamino]-3-hydroxy-6-methyl-heptanoylamino}-3-methyl-butyrylamino)-propionylamino]-butyric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433080; BDBM50127428
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[11] | |||
| Compound Name |
2-Amino-6-methyl-6-phenyl-5,6-dihydro-3h-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238087; SCHEMBL4142824; BDBM50226452; 2-amino-4-methyl-4-phenyl-1,5-dihydropyrimidin-6-one; 2-amino-6-methyl-6-phenyl-5,6-dihydropyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[18] | |||
| Compound Name |
5-{2-[3-Hydroxy-4-(2-hydroxy-2-naphthalen-1-yl-acetylamino)-6-methyl-heptanoylamino]-3-methyl-butyrylamino}-cyclohexane-1,3-dicarboxylic acid dimethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL53668; BDBM50127429
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[11] | |||
| Compound Name |
CID 54578013
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3261061; SCHEMBL2590141; BDBM50012641
Click to Show/Hide
|
||||
| Activity |
IC50 = 142000 nM
|
[67] | |||
| Compound Name |
Neocyclomorusin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1770314; BDBM50343140
Click to Show/Hide
|
||||
| Activity |
IC50 = 146100 nM
|
[27] | |||
| Compound Name |
2-Amino-3-methyl-6-phenethyl-3H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237888; SCHEMBL4142484; BDBM50226446; 2-amino-3-methyl-6-(2-phenylethyl)pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[18] | |||
| Compound Name |
Phenyl-substituted sulfonamides, 6c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487494; BDBM32386
Click to Show/Hide
|
||||
| Activity |
Ki = 150000 nM
|
[33] | |||
| Compound Name |
(4S)-5-[[(1S)-1-Carboxy-2-phenylethyl]amino]-4-[[(2S)-2-[[(2S)-2-[[4-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]-3-hydroxy-6-methylheptanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89773; BDBM50108553
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[29] | |||
| Compound Name |
(3R,4S,5S)-3-Amino-5-[[4-amino-3-fluoro-5-[(2R)-1,1,1-trifluoro-3-methoxypropan-2-yl]oxyphenyl]methyl]-1-oxothian-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2425615
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[68] | |||
| Compound Name |
Xestosaprol G
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164757; BDBM50321125
Click to Show/Hide
|
||||
| Activity |
IC50 = 155000 nM
|
[43] | |||
| Compound Name |
2-Amino-3-Methyl-6-[(1s,2r)-2-Phenylcyclopropyl]pyrimidin-4(3h)-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169926; BDBM50397278; Q27458150; 2-Amino-6-[(1S,2R)-2-phenylcyclopropyl]-3-methylpyrimidine-4(3H)-one; B00
Click to Show/Hide
|
||||
| Activity |
IC50 = 157000 nM
|
[16] | |||
| Compound Name |
2,3,4,5-Tetra(3,4,5-trihydroxyphenylcarbonyloxy)-6-(3,4,5-trihydroxyphenylcarbonyloxymethyl)-(2R,3S,4R,5S,6S)-tetrahydro-2H-pyran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127911; BDBM50135166; ZINC169316285; 1-O,2-O,3-O,4-O,6-O-Pentagalloyl-beta-L-glucopyranose
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 160000 nM
|
[69] | |||
| Compound Name |
Chembl4168528
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4060230; BDBM50450091; 2-[(E)-2-[(7-chloro-4-quinolyl)amino]ethyliminomethyl]phenol; 7-Chloro-4-[[2-[(2-hydroxybenzylidene)amino]ethyl]amino]quinoline
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 160000 nM
|
[63] | |||
| Compound Name |
[(1S,20R,22S,23R,24R)-7,8,9,12,13,14,23,24-Octahydroxy-4,17-dioxo-2,3,18,21-tetraoxatetracyclo[18.3.1.05,10.011,16]tetracosa-5,7,9,11,13,15-hexaen-22-yl] 3,4,5-trihydroxybenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303749; BDBM50451740
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 160000 nM
|
[69] | |||
| Compound Name |
Xestosaprol I
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164484; BDBM50321127
Click to Show/Hide
|
||||
| Activity |
IC50 = 163000 nM
|
[43] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[4-(5-methylthiophen-2-yl)phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169945; BDBM50397259
Click to Show/Hide
|
||||
| Activity |
IC50 = 165000 nM
|
[16] | |||
| Compound Name |
(S)-Methyl 2-((S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)pentanamido)-3-tert-butoxypropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222366; BDBM50324930
Click to Show/Hide
|
||||
| Activity |
IC50 = 168000 nM
|
[21] | |||
| Compound Name |
Latifolin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-[(1R)-1-(2-hydroxyphenyl)prop-2-enyl]-2,4-dimethoxyphenol; (R)-5,2'-Dihydroxy-2,4-dimethoxydalbergiquinol; NSC370336; (-)-(R)-Latifolin; SCHEMBL9418029; CHEMBL2397757; LATIFOLIN (+) - (R); BDBM50018963; LMPK12100064; NSC-370336
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[31] | |||
| Compound Name |
6-Chloro-3,3-dimethyl-N-[1-(1,3,4-oxadiazol-2-yl)-2-phenylethyl]-2,4-dihydroisoquinolin-1-imine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346792; BDBM50432183
Click to Show/Hide
|
||||
| Activity |
IC50 = 184900 nM
|
[40] | |||
| Compound Name |
6,7-Furano-5-prenyloxy hydrocoumaric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL589100; BDBM50308718
Click to Show/Hide
|
||||
| Activity |
IC50 = 185600 nM
|
[70] | |||
| Compound Name |
2-Amino-3-methyl-6-[2-(3-pyridin-3-ylphenyl)ethyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235753; SCHEMBL4146975; BDBM50226457; ZINC28826890; 6-(3-(pyridin-3-yl)phenethyl)-2-amino-3-methylpyrimidin-4(3H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[18] | |||
| Compound Name |
Isophthalamide Derivative 5f
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL387984; BDBM16261
Click to Show/Hide
|
||||
| Activity |
IC50 = 190000 nM
|
[71] | |||
| Compound Name |
4-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-isopropylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221978; BDBM50324904
Click to Show/Hide
|
||||
| Activity |
IC50 = 193000 nM
|
[21] | |||
| Compound Name |
4-(2-Amino-5-chlorobenzimidazol-1-yl)-N-[(3-fluorophenyl)methyl]-N-methylbutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222139; BDBM50324912; 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(3-fluorobenzyl)-N-methylbutanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 194000 nM
|
[21] | |||
| Compound Name |
CID 46927332
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1464805; SCHEMBL7887737; SCHEMBL7890498; CHEMBL3930817; CHEMBL3947373; BDBM113286; BDBM113288; US8633212, 64; US8633212, 66
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[8] | |||
| Compound Name |
4-Butoxy-3-chlorobenzyl imidothiocarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL568966; MLS001029844; SMR000427725; 2-(4-Butoxy-3-chloro-benzyl)-isothiourea; cid_16681813; BDBM114543; ZINC4713685; STK836579; AKOS005624338; MCULE-4204094514; 4-butoxy-3-chlorobenzyl carbamimidothioate; 2-(4-butoxy-3-chloro-benzyl)isothiourea;hydrochloride; Q27460489; (4-butoxy-3-chlorophenyl)methyl carbamimidothioate;hydrochloride; (4-butoxy-3-chloranyl-phenyl)methyl carbamimidothioate;hydrochloride; carbamimidothioic acid (4-butoxy-3-chlorophenyl)methyl ester;hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[5] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 148 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Methoxsalen
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Ammodin; Ammoidin; Deltasoralen; Dermox; Geroxalen; Meladinin; Meladinina; Meladinine; Meladoxen; Meloxine; Methoxalen; Methoxaten; Oxoralen; Oxsoralen; Oxypsoralen; Puvalen; Puvamet; Ultramop; Uvadex; XANTHOTOXIN; Xanthotoxine; Zanthotoxin; Boehringer Ingelheim Brand of Methoxsalen; Canderm Brand of Methoxsalen; Chinoin Brand of Methoxsalen; DB Brand of Methoxsalen; Delta Brand of Methoxsalen; Dermatech Brand of Methoxsalen; Galderma Brand of Methoxsalen; Methoxa Dome; Methoxsalen Canderm Brand; Methoxsalen Chinoin Brand; Methoxsalen Delta Brand; Methoxsalen Dermatech Brand; Methoxsalen plus ultraviolet radiation; Mex America Brand of Methoxsalen; Oxsoralen Ul tra; Oxsoralen Ultra; Oxsoralen lotion; Sanofi Synthelabo Brand of Methoxsalen; Ultra Mop; Ultramop Lotion; ICN Brand 1 of Methoxsalen; ICN Brand 2 of Methoxsalen; ICN Brand 3 of Methoxsalen; X0009; An 8-methoxyfurocoumarin; Meladinin (VAN); Methoxa-Dome; Methoxsalen Mex-America Brand; Methoxsalen Sanofi-Synthelabo Brand; Methoxsalen [BAN:JAN]; Methoxsalen with ultra-violet A theraphy; Mex-America Brand of Methoxsalen; New-Meladinin; O-methylxanthotoxol; OXSORALEN (TN); Oxsoralen (TN); Oxsoralen-ultra; Proralone-mop; Psoralen-mop; Psoralon-MOP; Sanofi-Synthelabo Brand of Methoxsalen; Methoxsalen (JP15/USP); Methoxy-8-psoralen; 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, .delta.-lactone; 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, delta-lactone; 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid delta-lactone; 7-Furocoumarin; 8 Methoxypsoralen; 8-METHOXYPSORALEN + UVA (SEE ALSO C55903); 8-MOP; 8-Methoxy; 8-Methoxy(furano-3'.2':6.7-coumarin); 8-Methoxy-(furano-3'.2':6.7-coumarin); 8-Methoxy-2',3',6,7-furocoumarin; 8-Methoxy-4',5',6,7-furocoumarin; 8-Methoxy-4',5':6,7-furocoumarin; 8-Methoxy-[furano-3'.2':6.7-coumarin]; 8-Methoxyfuranocoumarin; 8-Methoxypsoralen; 8-Methoxypsoralen with ultraviolet A therapy; 8-Methoxypsoralene; 8-methoxyfuranocoumarins; 8-methoxyfurocoumarins; 8MO; 8MOP; 9-(methyloxy)-7H-furo[3,2-g]chromen-7-one; 9-Methoxy-7H-furo(3,2-g)(1)benzopyran-7-one; 9-Methoxy-7H-furo(3,2-g)benzopyran-7-one; 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 9-Methoxy-7H-furo[3,2-g]chromen-7-one; 9-Methoxyfuro(3,2-g)chromen-7-one; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; 9-Methoxypsoralen; 9-metho xy-7H-furo(3,2-g)benzopyran-7-one; 9-methoxyfuro[3,2-g]chromen-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Curcumin
Click to Show/Hide
|
Phase 3 | Compound Info | ||
| Synonyms |
curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Turmeric yellow; Turmeric; Curcuma; Kacha haldi; Gelbwurz; Indian saffron; Curcumin I; Souchet; Halud; Halad; Haidr; Haldar; Merita earth; Yellow Ginger; Terra Merita; Yellow Root; Safran d'Inde; Yo-Kin; Golden seal; Curcuma oil; Orange Root; Oils, curcuma; CI Natural Yellow 3; Curcumine; Hydrastis; Indian turmeric; Yellow puccoon; Turmeric extract; Diferaloylmethane; Kurkumin [Czech]; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; Tumeric yellow; Turmeric oil
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||||
| Activity |
IC50 = 343000 nM
|
[72] | |||
| Compound Name |
Psoralen
Click to Show/Hide
|
Phase 3 | Compound Info | ||
| Synonyms |
Psoralen; 66-97-7; 7H-Furo[3,2-g]chromen-7-one; Ficusin; Furocoumarin; Psoralene; 7H-Furo[3,2-g][1]benzopyran-7-one; Psorline-P; 6,7-Furanocoumarin; furo[3,2-g]chromen-7-one; Furo[3,2-g]coumarin; Furo(4',5',6,7)coumarin; Furo(2',3',7,6)coumarin; Furo(3,2-g)-coumarin; Furo[4',5':6,7]coumarin; Furo[2',3':7,6]coumarin; NSC 404562; UNII-KTZ7ZCN2EX; 7H-Furo(3,2-g)(1)benzopyran-7-one; 7H-Furo[3,2-g]benzopyran-7-one; CCRIS 4343; Furo[2'.3':7.6]coumarin; HSDB 3528; KTZ7ZCN2EX; EINECS 200-639-7; 6-Hydroxy-5-benzofuranacrylic acid beta-lacto
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
5-methoxypsoralen
Click to Show/Hide
|
Phase 3 | Compound Info | ||
| Synonyms |
5-MOP
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
PMID27841045-Compound-129
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|
Patented | Compound Info | ||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
AS602868
Click to Show/Hide
|
Discontinued in Phase 1 | Compound Info | ||
| Synonyms |
Angelicin; ISOPSORALEN; 523-50-2; 2H-Furo[2,3-H]chromen-2-one; Angecin; furo[2,3-h]chromen-2-one; Isopsoralin; Furo(2,3-h)coumarin; Angelecin; Angelicin (coumarin derivative); 2H-Furo[2,3-H]-1-benzopyran-2-one; 2-Oxo-(2H)-furo(2,3-h)-1-benzopyran; UNII-CZZ080D7BD; Angelicin (coumarin deriv); NSC 404563; Furo(5',4':7,8)coumarin; CCRIS 4276; HSDB 3554; 4-Hydroxy-5-benzofuranacrylic acid gamma-lactone; BRN 0153970; CZZ080D7BD; 2H-Furo(2,3-H)-1-benzopyran-2-one; CHEMBL53569; Furo[5',4':7,8]coumarin; Isopsoralen
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
7-hydroxycoumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Umbelliferone; 93-35-6; 7-Hydroxy-2H-chromen-2-one; Skimmetin; Hydrangin; 7-hydroxycoumarine; 7-Oxycoumarin; Umbelliferon; Skimmetine; Hydrangine; 2H-1-Benzopyran-2-one, 7-hydroxy-; 7-Hydroxy-2H-1-benzopyran-2-one; Coumarin, 7-hydroxy-; beta-Umbelliferone; 7-hydroxychromen-2-one; 7 HC; UNII-60Z60NTL4G; 7-hydroxy-coumarin; NSC 19790; CCRIS 3591; NSC19790; EINECS 202-240-3; 7H-1-Benzopyran-7-one, 2-hydroxy-; BRN 0127683; CHEMBL51628; AI3-38054; 7-hydroxy-1-benzopyran-2-one; 7-HC; 60Z60NTL4G; CHEBI:27510; UMBELLIFERONE
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
COUMARIN
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
coumarin; 2H-Chromen-2-one; 91-64-5; 2H-1-Benzopyran-2-one; cumarin; 1,2-Benzopyrone; Rattex; Tonka bean camphor; Coumarinic anhydride; chromen-2-one; Coumarine; Benzo-alpha-pyrone; cis-o-Coumarinic acid lactone; o-Hydroxycinnamic acid lactone; o-Hydroxycinnamic lactone; 2-Oxo-1,2-benzopyran; Coumarinic lactone; Kumarin; Benzo-a-pyrone; Kumarin [Czech]; 5,6-Benzo-2-pyrone; 2H-1-Benzopyran, 2-oxo-; 5,6-Benzo-alpha-pyrone; 2H-Benzo(b)pyran-2-one; 2H-Benzo[b]pyran-2-one; Caswell No. 259C; o-Coumaric acid lactone
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
BERGAPTOL
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Bergaptol; 486-60-2; 5-Hydroxypsoralen; 4-Hydroxy-7H-furo[3,2-g]chromen-7-one; 5-Hydroxyfuranocoumarin; Psoralin, 5-hydroxy-; UNII-KTC8ANI30F; 4-Hydroxybergapten; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-hydroxy-; NSC341958; KTC8ANI30F; 4-oxidanylfuro[3,2-g]chromen-7-one; NSC 341958; 5-Hydroxy-6,7-furanocoumarin; CHEMBL242711; CHEBI:17377; GIJHDGJRTUSBJR-UHFFFAOYSA-N; 4-hydroxyfuro[3,2-g]chromen-7-one; AK158894; Bergaptols; 5-Hydroxy-Psoralen; 5-Hydroxyfurocoumarin; AC1NQWYH; 5-HYDROXY-PSORALIN; 7H-Furo[3, 4-hydroxy-; BSPBio_002390
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
HERNIARIN
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-Methoxycoumarin; Herniarin; 531-59-9; 7-Methoxy-2H-chromen-2-one; Ayapanin; Herniarine; Methylumbelliferone; 7-Methoxy-2H-1-benzopyran-2-one; 7-methoxychromen-2-one; 2H-1-BENZOPYRAN-2-ONE, 7-METHOXY-; Coumarin, 7-methoxy-; METHOXYCOURMARIN, 7-; Herniarin (6CI); Methyl umbelliferyl ether; UNII-DGK72G008A; 7-methoxy-coumarin; 7-Methoxy Coumarin; NSC 404559; 7-(methyloxy)-2H-chromen-2-one; EINECS 208-513-3; 7-methoxy-chromen-2-one; BRN 0141728; CHEMBL49732; CHEBI:5679; DGK72G008A; Coumarin, 7-methoxy- (8CI)
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
esculetin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
aesculetin; 6,7-dihydroxycoumarin; cichorigenin
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
(6S)-2-Amino-3,6-dimethyl-6-[(1R,2S)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437448; BDBM50493638
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|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
(4S)-4-[[(2S)-2-[[(2R)-1-[4-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxy-6-methylheptanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-5-[[(1S)-1-carboxy-2-phenylethyl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420418; BDBM50108546
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|
||||
| Activity |
IC50 > 200000 nM
|
[29] | |||
| Compound Name |
Chembl415810
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370123; BDBM50108519; NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta(S-OAc)-D-A-E-F; Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-O-Acetyl-Sta-Asp-Ala-Glu-Phe-OH
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|
||||
| Activity |
IC50 > 200000 nM
|
[29] | |||
| Compound Name |
Chembl267608
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370091; BDBM50108525; NH2-Thr-Asn-Ile-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Thr-Asp-Ala-Glu-Phe-Arg
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[29] | |||
| Compound Name |
2-Amino-6-[2-[4-(3-ethylsulfanylphenyl)phenyl]ethyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169925; BDBM50397240
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|
||||
| Activity |
IC50 > 200000 nM
|
[16] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[3-(3-aminophenyl)phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381675; BDBM50491269
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|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
2-Amino-3-methyl-6-[2-[3-(2-phenylethyl)phenyl]ethyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381577; BDBM50491268
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|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-(2-phenylethynyl)phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381572; SCHEMBL15427629; BDBM50491274
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|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-(3-benzylphenyl)cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381679; SCHEMBL15427665; BDBM50491259
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
(6R)-2-Amino-3,6-dimethyl-6-[(1S,2R)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437447; BDBM50493653
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-[2-(3-methylphenyl)ethyl]phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381574; BDBM50491263
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
(6S)-2-Amino-3,6-dimethyl-6-(2-phenylethyl)-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437453; BDBM50493652
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|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
2-Amino-3-methyl-6-[2-(4-phenylphenyl)ethyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169941; BDBM50397263
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|
||||
| Activity |
IC50 > 200000 nM
|
[16] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-[2-(4-methylphenyl)ethyl]phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381575; BDBM50491272
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
(6R)-2-Amino-3,6-dimethyl-6-[(1R,2S)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437451; BDBM50493639
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|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-[(E)-2-phenylethenyl]phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381682; SCHEMBL15427631; BDBM50491264
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
(6R)-2-Amino-3,6-dimethyl-6-[(1S,2S)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437455; BDBM50493640
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-[3-[3-(dimethylamino)phenyl]phenyl]cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381581; BDBM50491273
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
(6S)-2-Amino-3,6-dimethyl-6-[(1S,2R)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437450; BDBM50493651
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
(6R)-2-Amino-3,6-dimethyl-6-[(1R,2R)-2-phenylcyclopropyl]-5H-pyrimidin-4-one;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2437456; BDBM50493645
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[64] | |||
| Compound Name |
Chembl405482
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370095; BDBM50108533; NH2-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta(R-OH)-D-A-E-F
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[29] | |||
| Compound Name |
[1-(1-{1-[2-(1-Cyclohexylcarbamoyl-2-methyl-propylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-3-methylsulfanyl-propylcarbamoyl)-2-methyl-propyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298141; BDBM50127420
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
[1-(1-{1-[2-(1-Butylcarbamoyl-2-methyl-propylcarbamoyl)-1-hydroxy-ethyl]-3-methyl-butylcarbamoyl}-3-methylsulfanyl-propylcarbamoyl)-2-methyl-propyl]-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52225; BDBM50127437
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
{1-[1-(1-{2-[1-(Cyclohexylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-1-hydroxy-ethyl}-3-methyl-butylcarbamoyl)-3-methylsulfanyl-propylcarbamoyl]-2-methyl-propyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49711; BDBM50127418
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
2-[[(2S)-Butan-2-yl]amino]-N-[(1R,2S)-1-hydroxy-3-phenyl-1-[(2S)-pyrrolidin-2-yl]propan-2-yl]-6-methylsulfonylpyridine-4-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4076855; BDBM50250526
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[73] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-[3-(3-phenylpropyl)phenyl]cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2381681; BDBM50491265
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[39] | |||
| Compound Name |
6,7-Furano-8a-methoxy-5-prenyloxy hydrocoumaric acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL589416; BDBM50308721
Click to Show/Hide
|
||||
| Activity |
IC50 = 203300 nM
|
[70] | |||
| Compound Name |
6,7-Furano-5-prenyloxy hydrocoumaric acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL592382; BDBM50308720
Click to Show/Hide
|
||||
| Activity |
IC50 = 203300 nM
|
[70] | |||
| Compound Name |
4-(1-Phenylcyclopentyl)-2-Thiazolamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL511383; 4-(1-phenylcyclopentyl)-1,3-thiazol-2-amine; Oprea1_347470; Oprea1_380478; SCHEMBL3139632; ZINC288917; BDBM50258845; AKOS000507004; 4-(1-phenylcyclopentyl)thiazol-2-amine; DS-016691
Click to Show/Hide
|
||||
| Activity |
IC50 = 217000 nM
|
[74] | |||
| Compound Name |
2,3,4,4-Tetramethyl-5-methylene-2-cyclopentene-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2272783; SCHEMBL18121638; CTK3C7199; DTXSID70467585; BDBM50023040; 5-methylene-2,3,4,4-tetramethylcyclopent-2-enone; 2-Cyclopenten-1-one, 2,3,4,4-tetramethyl-5-methylene-
Click to Show/Hide
|
||||
| Activity |
EC50 = 217000 nM
|
[75] | |||
| Compound Name |
Aminopyrimidine, 18
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467636; BDBM26498; N-(2-methyl-5-{[6-(2-methylphenyl)pyrimidin-4-yl]amino}phenyl)methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 219000 nM
|
[36] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-5-methyl-N-(pyridin-2-ylmethyl)hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221453; BDBM50324933; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-5-methyl-N-(pyridin-2-ylmethyl)hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 235000 nM
|
[21] | |||
| Compound Name |
[(3R)-3-Benzylmorpholin-4-yl]-[(3S,4R)-4-phenylpyrrolidin-3-yl]methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934284; BDBM50360712
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|
||||
| Activity |
IC50 = 240000 nM
|
[25] | |||
| Compound Name |
Methyl (3s,5'r)-2-Oxo-1,2-Dihydrospiro[indole-3,3'-Pyrrolidine]-5'-Carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2181997; BDBM50397739; Q27449917
Click to Show/Hide
|
||||
| Activity |
IC50 = 242000 nM
|
[44] | |||
| Compound Name |
(S)-3-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclopropylmethyl)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222238; BDBM50324920
Click to Show/Hide
|
||||
| Activity |
IC50 = 243000 nM
|
[21] | |||
| Compound Name |
Isoimperatorin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Iso-imperatorin; 4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one; 4-PRENYLOXYPSORALEN; UNII-0ZMV066080; 4-[(3-methylbut-2-en-1-yl)oxy]-7h-furo[3,2-g]chromen-7-one; CHEMBL448060; 0ZMV066080; 4-((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one; Iso Imperatorin; 7,4-[(3-methyl-2-butenyl)oxy]-7H-furo[3,2-g]-1-benzopyran-7-one; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-((3-methyl-2-butenyl)oxy)-; SMR000156243; Auraptin; Cnidin; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-((3-methyl-2-butenyl)oxy)-; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-[(3-methyl-2-butenyl)oxy]-; Oprea1_630212; Oprea1_655950; MLS000574919; MLS001048978; MEGxp0_000090; SCHEMBL15090959; ACon1_000176; CTK4J0732; HSDB 8496; DTXSID60197460; HMS2268M21; Isoimperatorin, analytical standard; ZINC296185; BCP10721; HY-N0286; KS-00000NN4; BDBM50242377; CI0035; MFCD00272155; s3904; STL564896; 7H-Furo[3,2-g][1]benzopyran-7-one,4-[(3-methyl-2-buten-1-yl)oxy]-; AKOS015895143; AC-8047; ACN-035226; CCG-267156; CS-5801; MCULE-5468436292; NCGC00180809-01; AK-23906; BS-17328; AB0019796; DB-050314; FT-0656369; N1746; V0302; A14550; C16976; 482I451; Q-100533; Q1552561; BRD-K40367461-001-01-0; 4-(3-methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one; 4-[(3-Methyl-2-butenyl)oxy]-7H-furo[3,2-g]chromen-7-one #; 7H-Furo[3,2-g][1]benzopyran-7-one,4-[(3-methyl-2-butenyl)oxy]-; NCGC00180809-02!4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
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||||
| Activity |
IC50 = 244200 nM
|
[2] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-5-methyl-N-propan-2-ylhexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222235; BDBM50324917; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-isopropyl-5-methylhexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 246000 nM
|
[21] | |||
| Compound Name |
4-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(3-fluorobenzyl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222033; BDBM50324910
Click to Show/Hide
|
||||
| Activity |
IC50 = 249000 nM
|
[21] | |||
| Compound Name |
Phenyl-substituted sulfonamides, 6a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487288; BDBM32384
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
6-Chloro-3,3-dimethyl-N-[1-(4-methylpyrimidin-2-yl)-2-phenylethyl]-2,4-dihydroisoquinolin-1-imine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346795; BDBM50432180
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[40] | |||
| Compound Name |
Iso-butyl-substituted sulfonamide, 9a
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL521590; BDBM32390
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
Carboxamide, 12c
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL487493; BDBM32394; N-benzyl-N-[3-[3-[benzyl-(2-phenylacetyl)amino]propylamino]propyl]-2-phenylacetamide
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
(1E,4Z,6E)-7-(3,4-Dihydroxyphenyl)-5-hydroxy-1-(2-hydroxyphenyl)hepta-1,4,6-trien-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3103052; BDBM50495220
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[76] | |||
| Compound Name |
Carboxamide, 12a
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL489368; BDBM32392; N-benzyl-N-[2-[2-[benzyl-(2-phenylacetyl)amino]ethylamino]ethyl]-2-phenylacetamide
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
N,N'-(Iminodiethane-2,1-Diyl)bis[4-Amino-N-(2-Methylpropyl)benzenesulfonamide]
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL490184; BDBM32391; iso-butyl-substituted sulfonamide, 9b; Q27462569
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
Phenyl-substituted sulfonamides, 6e
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL505405; BDBM32388
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
Carboxamide, 12b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488104; BDBM32393; N-benzyl-N-[3-[2-[benzyl-(2-phenylacetyl)amino]ethylamino]propyl]-2-phenylacetamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
N,N'-(Iminodiethane-2,1-diyl)bis(4-amino-N-benzylbenzenesulfonamide)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL519079; BDBM32387; phenyl-substituted sulfonamides, 6d; Q27462568; LJH
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
3-[2-(3-{[(Furan-2-ylmethyl)(methyl)amino]methyl}phenyl)ethyl]pyridin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569654; 3TO; BDBM50300239; Q27454130; 3-(3-(((furan-2-ylmethyl)(methyl)amino)methyl)phenethyl)pyridin-2-amine
Click to Show/Hide
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||||
| Activity |
IC50 = 250000 nM
|
[77] | |||
| Compound Name |
Phenyl-substituted sulfonamides, 6b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521384; BDBM32385
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[33] | |||
| Compound Name |
1,4-Diamino-2,3-bis-(4-ethyl-phenylsulfanyl)-anthraquinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165724; 1,4-diamino-2,3-bis(4-ethylphenylthio)anthracene-9,10-dione; ChemDiv1_000521; HMS588H15; ZINC6197627; 1,4-diamino-2,3-bis[(4-ethylphenyl)sulfanyl]anthracene-9,10-dione; BDBM50320668; STK759923; AKOS001600423; MCULE-3139449279; ST047487; AG-205/12084145; 1,4-diamino-2,3-bis[(4-ethylphenyl)sulfanyl]anthra-9,10-quinone
Click to Show/Hide
|
||||
| Activity |
IC50 = 253000 nM
|
[9] | |||
| Compound Name |
(2R)-2-[(6-Chloro-3,3-dimethyl-2,4-dihydroisoquinolin-1-ylidene)amino]-3-phenylpropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380805
Click to Show/Hide
|
||||
| Activity |
IC50 = 263800 nM
|
[78] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-[(4-fluorophenyl)methyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222365; BDBM50324929; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(4-fluorobenzyl)pentanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 264000 nM
|
[21] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(2-pyrrolidin-3-ylethyl)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222239; BDBM50324921; (3S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(2-(pyrrolidin-3-yl)ethyl)pentanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 270000 nM
|
[21] | |||
| Compound Name |
5-[3-(3,5-Bis-trifluoromethyl-phenyl)-ureido]-2-dimethylamino-N-(3-methoxy-propyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363539; BDBM50171338
Click to Show/Hide
|
||||
| Activity |
IC50 = 283900 nM
|
[79] | |||
| Compound Name |
N-[5-({6-[2-(Dimethylamino)phenyl]pyrimidin-4-yl}amino)-2-methylphenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
N-[5-[[6-[2-(dimethylamino)phenyl]pyrimidin-4-yl]amino]-2-methylphenyl]methanesulfonamide; CHEMBL465988; BDBM26496
Click to Show/Hide
|
||||
| Activity |
IC50 = 317000 nM
|
[36] | |||
| Compound Name |
N-[[4-(Aminomethyl)phenyl]methyl]-2-(4-phenylphenyl)acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322833
Click to Show/Hide
|
||||
| Activity |
IC50 = 323000 nM
|
[26] | |||
| Compound Name |
4-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(1-methylpiperidin-4-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222032; BDBM50324909; 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(1-methylpiperidin-4-yl)butanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 325000 nM
|
[21] | |||
| Compound Name |
6-Bromoquinolin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Amino-6-bromoquinoline; 6-Bromo-quinolin-2-ylamine; 6-bromo-2-Quinolinamine; (6-Bromoquinolin-2-yl)amine; CHEMBL189197; 6-Bromo-2-aminoquinoline; 2-Quinolinamine,6-bromo-; ACMC-209pgi; SCHEMBL9312; CTK8B2326; DTXSID00457979; ANW-37264; BDBM50154591; MFCD06738670; ZINC13584273; AKOS013154493; GS-6166; KS-0000268P; AC-23309; BR-36400; QC-10793; AB0026747; FT-0700545; W8483; S-7161; J-501656; F9995-2572; 2,2,3,3,5,5,6,6-OCTAFLUORO-4,4-BIPHENYLDICARBONITRILE
Click to Show/Hide
|
||||
| Activity |
IC50 = 338000 nM
|
[80] | |||
| Compound Name |
6-Chloro-3,3-dimethyl-N-[1-(5-methyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-2,4-dihydroisoquinolin-1-imine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346793; BDBM50432182
Click to Show/Hide
|
||||
| Activity |
IC50 = 339700 nM
|
[40] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-[(3-fluorophenyl)methyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221421; BDBM50324928; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(3-fluorobenzyl)pentanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 340000 nM
|
[21] | |||
| Compound Name |
Auraptene
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Aurapten; 7-Geranyloxycoumarin; UNII-F79I1ZEL2E; F79I1ZEL2E; 2H-1-Benzopyran-2-one, 7-((3,7-dimethyl-2,6-octadienyl)oxy)-, (E)-; (E)-7-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one; 7-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-chromen-2-one; SR-01000758940; 7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one; Feronialactone; 7-([(2E)-3,7-Dimethyl-2,6-octadienyl]oxy)-2H-chromen-2-one; 7-{[(2E)-3,7-dimethyl-2,6-octadienyl]oxy}-2H-chromen-2-one; CCRIS 8835; 2H-1-Benzopyran-2-one, 7-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)-; 7-O-geranylumbelliferone; UPCMLD-DP061; Coumarin, 7-(geranyloxy)-; MLS001049098; SPECTRUM1505176; CHEMBL307341; MEGxp0_000091; SCHEMBL2535029; SCHEMBL2535034; Auraptene, >=98% (HPLC); UPCMLD-DP061:001; ACon1_000071; DTXSID80897576; HMS2270C13; HMS3886N14; NP344; BCP23751; HY-N2388; ZINC1658901; BDBM50361373; MFCD00075948; NSC711511; s9052; STL457597; AKOS015969736; CCG-208550; MCULE-3823939164; NSC-711511; NCGC00096070-01; NCGC00096070-03; NCGC00096070-04; NCGC00096070-05; NCGC00096070-11; NCGC00168822-01; SMR000386931; CS-0022591; W1305; Q3629783; SR-01000758940-3; SR-01000758940-4; 7-(3,7-Dimethyl-octa-2,6-dienyloxy)-chromen-2-one; 7-[(3,7-Dimethyl-2,6-octadienyl)oxy]-(E)-Coumarin; BRD-K85013741-001-05-9; Coumarin, 7-[(3,7-dimethyl-2,6-octadienyl)oxy]-, (E)-; (E)-7-(3,7-dimethylocta-2,6-dienyloxy)-2H-chromen-2-one; 7-([(2E)-3,7-Dimethyl-2,6-octadienyl]oxy)-2H-chromen-2-one #; 7-(3,7-Dimethyl-2,6-octadienyl)oxy-2H-1-benzopyran-2-one, 9CI; 2H-1-Benzopyran-2-one, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-; 7-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-1-benzopyran-2-one; NCGC00096070-07!7-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one
Click to Show/Hide
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||||
| Activity |
IC50 = 345100 nM
|
[2] | |||
| Compound Name |
Oxypseucedanin
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Oxypeucedanin; CCRIS 5725; UNII-S1Y67F37PI; S1Y67F37PI; 4-[[(2S)-3,3-dimethyloxiran-2-yl]methoxy]furo[3,2-g]chromen-7-one; (?)-Oxypeucedanine; CHEMBL510120; DTXSID70948965; ZINC518644; BDBM50361376; AKOS037515166; C09282; Q27104977; 4-[(3,3-Dimethyloxiran-2-yl)methoxy]-7H-furo[3,2-g][1]benzopyran-7-one; 4-{[(2S)-3,3-dimethyloxiran-2-yl]methoxy}-7H-furo[3,2-g][1]benzopyran-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 359200 nM
|
[2] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(cyclohexylmethyl)-N-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222297; BDBM50324923; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(cyclohexylmethyl)-N-methylpentanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 375000 nM
|
[21] | |||
| Compound Name |
5-Bromoquinolin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-BROMO-QUINOLIN-2-YLAMINE; CHEMBL1821800; 5-bromo-2-aminoquinoline; 2-Quinolinamine, 5-bromo-; SCHEMBL3067674; CTK1B1001; 2-AMINO-5-BROMOQUINOLINE; DTXSID60627510; 3166AJ; BDBM50351911; MFCD11108679; ZINC26474716; AKOS023554088; CM10587; MB09289; AS-41824; Z-7127
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[80] | |||
| Compound Name |
N-{3-[(6-Phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451360; SCHEMBL8516577; BDBM26485
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[36] | |||
| Compound Name |
Demethylsuberosin
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
7-Demethylsuberosin; 7-demethylsuberosine; 7-hydroxy-6-(3-methylbut-2-enyl)chromen-2-one; UNII-SDM71QIW25; SDM71QIW25; CHEMBL502689; 2H-1-Benzopyran-2-one, 7-hydroxy-6-(3-methyl-2-butenyl)-; 7-hydroxy-6-prenylcoumarin; BEN267; MEGxp0_001461; SCHEMBL4773171; DTXSID90175695; HY-N2488; 9336AF; BDBM50292574; ZINC12153561; MCULE-4721059845; 7-hydroxy-6-prenyl-1-benzopyran-2-one; 6-(3,3-dimethylallyl)-7-hydroxycoumarin; CS-0022759; FT-0777068; C18083; Q27137383; 7-hydroxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 7-hydroxy-6-(3-methyl-2-buten-1-yl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 412900 nM
|
[2] | |||
| Compound Name |
4-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(pyridin-2-ylmethyl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222030; BDBM50324907; 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(pyridin-2-ylmethyl)butanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 426000 nM
|
[21] | |||
| Compound Name |
(1R,2S,6R)-2-[2-Fluoro-5-[(5-fluoro-3-methoxy-1,7-naphthyridin-8-yl)amino]phenyl]-2-(fluoromethyl)-5-oxa-3-azabicyclo[4.1.0]hept-3-en-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3688768; SCHEMBL16077300; BDBM171714; US9085576, 344
Click to Show/Hide
|
||||
| Activity |
IC50 = 430000 nM
|
[81] | |||
| Compound Name |
(3S)-3-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(2-morpholin-4-ylethyl)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222237; BDBM50324919; (S)-3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(2-morpholinoethyl)pentanamide
Click to Show/Hide
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||||
| Activity |
IC50 = 440000 nM
|
[21] | |||
| Compound Name |
Heraclenin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-G71S84CX12; 9-[[(2R)-3,3-dimethyloxiran-2-yl]methoxy]furo[3,2-g]chromen-7-one; G71S84CX12; Prengenine; (+)-Heraclenin; NSC92228; CCRIS 5727; NSC 92228; CHEMBL500034; DTXSID40182990; ZINC518797; HY-N4053; BDBM50361379; MFCD01725710; AKOS032948388; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-((3,3-dimethyloxiranyl)methoxy)-, (R)-; CS-0024542; Q27278868; 7H-FURO(3,2-g)(1)BENZOPYRAN-7-ONE, 9-(2,3-EPOXY-3-METHYLBUTOXY)-, (R)-(+)-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[[(2R)-3,3-dimethyloxianyl]methoxy]-
Click to Show/Hide
|
||||
| Activity |
IC50 = 443600 nM
|
[2] | |||
| Compound Name |
4-(2-Amino-5-chlorobenzimidazol-1-yl)-N-(2-pyrrolidin-3-ylethyl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222029; BDBM50324906; 4-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(2-(pyrrolidin-3-yl)ethyl)butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 444000 nM
|
[21] | |||
| Compound Name |
(1E,4Z,6E)-7-(3,4-Dihydroxyphenyl)-5-hydroxy-1-(1H-indol-3-yl)hepta-1,4,6-trien-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3103055; BDBM50495219
Click to Show/Hide
|
||||
| Activity |
IC50 = 450000 nM
|
[76] | |||
| Compound Name |
7-Bromoquinolin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Amino-7-Bromo Quinoline; 2-Quinolinamine, 7-bromo-; CHEMBL1821799; MFCD08062656; 7-bromo-aminoquinoline; 7-bromo-2-quinolinamine; 7-bromanylquinolin-2-amine; 2-Amino-7-bromo-quinoline; SCHEMBL18317038; CTK8G6332; 2-AMINO-7-BROMOQUINOLINE; DTXSID90670458; KS-00000R9U; BDBM50351910; ZINC40435290; AKOS015897024; CS-W006476; DS-5344; MB05231; AK126950; SC-52642; SY111832; DB-060899; FT-0656170; W-1447; A803655
Click to Show/Hide
|
||||
| Activity |
IC50 = 460000 nM
|
[80] | |||
| Compound Name |
2-Amino-6-(3,4-dichloro-phenyl)-5,6-dihydro-3H-pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL235763; SCHEMBL4136824; BDBM50226451; 2-amino-4-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrimidin-6-one; 2-amino-6-(3,4-dichlorophenyl)-5,6-dihydropyrimidin-4(3H)-one
Click to Show/Hide
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||||
| Activity |
IC50 = 480000 nM
|
[18] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2S,3S)-4-[[(1S)-1-carboxybutyl]amino]-1-cyclohexyl-3-hydroxy-4-oxobutan-2-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604695; BDBM50110901
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|
||||
| Activity |
IC50 = 480000 nM
|
[24] | |||
| Compound Name |
4-(6-Oxo-7,7-diphenylheptanamido)butanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164432; BDBM50320679
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
N-[(2S,3S)-4-[[(2S)-1-(Cyclohexylamino)-1-oxopropan-2-yl]amino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylsulfonylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256581; BDBM50373802
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[30] | |||
| Compound Name |
3-Methyl-2-[[2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]acetyl]amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Z-Gly-Gly-Val; CHEMBL1164333; Z-Gly-Gly-Val-OH; DTXSID90395912; BDBM50320683; AKOS024319368; MCULE-7997165823; ST50410885; 11-isopropyl-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid
Click to Show/Hide
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Dihydroxanthyletin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934198; SCHEMBL4741095; BDBM50361394; AKOS000278012; 2,2-dimethyl-3,4-dihydropyrano[3,2-g]chromen-8-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
9-Hydroxy-4-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934070; BDBM50361384
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
N-[(2R,3S)-1-[[(2S)-1-(Cyclohexylamino)-1-oxopropan-2-yl]amino]-2-hydroxy-5-methylhexan-3-yl]-3-methylsulfonylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL256162; BDBM50373803
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[30] | |||
| Compound Name |
Oxypeucedanin hydrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oxypeucedaninhydrate; Prangolarin hydrate; Hydroxypeucedanin hydrate; Aviprin; (+)-Oxypeucedanin hydrate; (R)-oxypeucedanin hydrate; CHEMBL454060; Prawgol; 4-[(2R)-2,3-dihydroxy-3-methylbutoxy]furo[3,2-g]chromen-7-one; Prangol; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-(2,3-dihydroxy-3-methylbutoxy)-, (R)-; 7H-FURO(3,2-g)(1)BENZOPYRAN-7-ONE, 4-(2,3-DIHYDROXY-3-METHYLBUTOXY)-, (R)-(+)-; MLS000574909; DTXSID90949318; HMS2196F22; ZINC477938; HY-N2622; BDBM50361377; AKOS000278024; SMR000156244; CS-0023028; Q27138170; 4-[(2R)-2,3-dihydroxy-3-methyl-butoxy]furo[3,2-g]chromen-7-one; 4-(2,3-Dihydroxy-3-methylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
N''-(3-Bromo-4-hydroxy-5-methoxybenzylidene)-2-(2-phenoxyethoxy)benzohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163708; ZINC9507038; BDBM50320685
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
7-Prenyloxycoumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-Prenylumbelliferone; CHEMBL156692; DIMETHYLALLYLUMBELLIFERONE, 0-; 7-(3-METHYL-2-BUTENYLOXY)COUMARIN; 7-[(3-methylbut-2-en-1-yl)oxy]-2H-chromen-2-one; 7-((3-Methylbut-2-en-1-yl)oxy)-2H-chromen-2-one; NSC267697; 7-(3-methylbut-2-enoxy)chromen-2-one; 7-(Prenyloxy)coumarin; 7-O-Prenylumbelliferone; MLS001049095; SCHEMBL4898255; DTXSID50313213; HMS2271J13; ZINC388776; 7-(3,3-Dimethylallyloxy)Coumarin; HY-N7023; BDBM50361372; STK921054; 7-(3-Methyl-2-butenyloxy) coumarin; AKOS001064505; MCULE-9019842665; NSC-267697; SMR000386928; DS-001640; CS-0101590; FT-0775302; 7-[(3-methyl-2-butenyl)oxy]-2H-chromen-2-one; SR-01000234416; SR-01000234416-1; 2H-1-BENZOPYRAN-2-ONE,7-[(3-METHYL-2-BUTEN-1-YL)OXY]-
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Marmesin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(+)-Marmesin; S-(+)-Marmesin; (S)-Marmesin; (7S)-marmesin; UNII-H5D33D6K5D; MARMESIN, (+)-; CHEMBL442813; H5D33D6K5D; (2S)-2-(1-hydroxy-1-methylethyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one; (S)-2-(2-Hydroxypropan-2-yl)-2H-furo[3,2-g]chromen-7(3H)-one; (2S)-2-(2-hydroxypropan-2-yl)-2,3-dihydrofuro[3,2-g]chromen-7-one; (+)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one; (S)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one; (S)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one; CCRIS 5728; S(+)-Marmesin; NSC 340840; Spectrum_001516; SpecPlus_000918; Spectrum2_000737; Spectrum3_001642; Spectrum4_001701; Spectrum5_000402; BSPBio_003363; KBioGR_002022; KBioSS_001996; DivK1c_007014; SPBio_000694; MEGxp0_001933; 2-(1-Hydroxy-1-methylethyl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one #; SCHEMBL12062107; HSDB 8478; KBio1_001958; KBio2_001996; KBio2_004564; KBio2_007132; KBio3_002583; ZINC51924; HY-N2176; BDBM50250917; CCG-40145; MFCD01725701; NSC340840; s3283; AKOS021983162; CS-7901; MCULE-3509624985; MCULE-4926964615; NSC-340840; SDCCGMLS-0066759.P001; C09276; AB00053150-02; BRD-K36377456-001-02-0; Q13847605; 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (+)-; 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-; 7H-Furo[3, 2,3-dihydro-2-(1-hydroxy-1-methylethyl)-, (S)-(+)-; (2S)-2,3-dihydro-2-(1-hydroxy-1-methylethyl)-7H-furo[3,2-g][1]benzopyran-7-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
8-Hydroxybergapten
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|
Investigative | Compound Info | ||
| Synonyms |
9-Hydroxy-4-methoxypsoralen; CHEMBL1934069; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-hydroxy-4-methoxy-; 9-hydroxy-4-methoxyfuro[3,2-g]chromen-7-one; 9-Hydroxybergapten; 8-hydroxy-5-methoxypsoralen; 9-Hydroxy-5-methoxypsoralen; 5-methoxy-8-hydroxy psoralen; 5-Methoxy-8-hydroxy-psoralen; SCHEMBL6361059; MVJHUMZXIJPVHV-UHFFFAOYSA-; DTXSID20166854; HY-N6010; BDBM50361383; ZINC13322992; AKOS000277887; CS-0032148; FT-0775442; 9-hydroxy-5-methoxy-2H-furo[3,2-g]chromen-2-one; 9-Hydroxy-4-methoxy-7H-Furo(3,2-g)(1)benzopyran-7-one; 9-Hydroxy-4-methoxyfuro[3,2-g][1]benzopyran-7-one, 9CI
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
2-(2-(2-(2-Oxo-4-propyl-2H-chromen-7-yloxy)acetamido)acetamido)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164433; ZINC2140328; BDBM50320680; EiM07-17339; STL461027; AKOS016379517; MCULE-6329787353; N-{[(2-oxo-4-propyl-2H-chromen-7-yl)oxy]acetyl}glycylglycine
Click to Show/Hide
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Heraclenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-9WSY53477L; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-; 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]furo[3,2-g]chromen-7-one; 9WSY53477L; NSC 306227; MLS000574834; CHEMBL1173444; CTK4G7389; DTXSID60185468; HMS2209F04; HY-N4052; ZINC1568212; 7H-Furo[3,2-g][1]benzopyran-7-one,9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-; AKOS037515115; Heraclenol, >=95% (LC/MS-ELSD); SMR000156207; CS-0024539; Q3785098; 9-[(2R)-2,3-dihydroxy-3-methyl-butoxy]furo[3,2-g]chromen-7-one; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-, (R)-
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
4-[(2E)-3,7-Dimethylocta-2,6-dienoxy]-9-hydroxyfuro[3,2-g]chromen-7-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1934071; BDBM50361385
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|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
5-(4-Morpholino-3-(p-tolylcarbamoyl)phenylamino)-5-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164329; ZINC6389321; BDBM50320678
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Xanthyletin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Xanthyletine; 2,2-dimethylpyrano[3,2-g]chromen-8-one; UNII-3N789LD38N; Spectrum_000673; SpecPlus_000132; CHEMBL303846; 3N789LD38N; 8,8-Dimethyl-8H-pyrano[3,2-g]chromen-2-one; 8,8-Dimethyl-2H,8H-benzo(1,2-b:5,4-b')dipyran-2-one; 8,8-dimethyl-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one; Spectrum2_000365; Spectrum3_000124; Spectrum4_001401; Spectrum5_000162; BSPBio_001768; KBioGR_001782; KBioSS_001153; SPECTRUM100609; cid_65188; MLS000863611; DivK1c_006228; SPBio_000489; MEGxp0_000991; SCHEMBL2120500; ACon1_000507; KBio1_001172; KBio2_001153; KBio2_003721; KBio2_006289; KBio3_000928; DTXSID60203818; HMS2269H15; ZINC338304; HY-N4116; BDBM50292575; CCG-38639; AKOS000278141; MCULE-4193827138; SDCCGMLS-0066430.P001; NCGC00095444-01; NCGC00095444-02; NCGC00095444-03; SMR000440697; CS-0032126; C09317; 2,2-dimethyl-8-pyrano[3,2-g][1]benzopyranone; A830590; SR-01000780630; 8,8-Dimethyl-2H,8H-pyrano[3,2-g]chromen-2-one; SR-01000780630-2; 8,8-Dimethyl-2H,8H-pyrano[3,2-g]chromen-2-one #; BRD-K28108221-001-02-3; Q27108571; 2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one, 8,8-dimethyl-; NCGC00095444-05!2,2-dimethylpyrano[3,2-g]chromen-8-one
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|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
2-(2,4-Dichlorobenzylamino)-2-oxoethyl 2-hydroxy-3-methoxybenzoate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164434; BDBM50320686
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Isopimpinellin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5,8-Dimethoxypsoralen; 5,8-Dimethoxypsoralene; 4,9-dimethoxyfuro[3,2-g]chromen-7-one; 4,9-Dimethoxy-furo[3,2-g]chromen-7-one; 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one; 7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dimethoxy-; UNII-20GCF755G6; 5,8-Dimethoxy-6,7-furanocoumarin; NSC401288; 4,9-Dimethoxy-7H-furo(3,2-G) (1)benzopyran-7-one; 20GCF755G6; 7H-Furo[3, 4,9-dimethoxy-; MFCD00017407; CCRIS 4347; NSC 217988; NSC 401288; Dimethylpsoralen; Spectrum_000624; SpecPlus_000154; 5, 8-Dimethoxypsoralene; Spectrum2_000308; Spectrum3_001232; Spectrum4_001442; Spectrum5_000023; Oprea1_132007; Oprea1_593894; BSPBio_002704; KBioGR_001923; KBioSS_001104; SPECTRUM300012; MLS000876836; DivK1c_006250; SCHEMBL498907; 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one; SPBio_000276; 7H-Furo[3,2-g][1]benzopyran-7-one,4,9-dimethoxy-; CHEMBL140796; MEGxp0_000706; ACon1_002361; CTK4J0725; DFMAXQKDIGCMTL-UHFFFAOYSA-; HSDB 8477; KBio1_001194; KBio2_001104; KBio2_003672; KBio2_006240; KBio3_002204; DTXSID30197457; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dimethoxy- (8CI); HMS2270M12; Isopimpinellin, analytical standard; ZINC314951; HY-N0769; BDBM50361386; CCG-38585; NSC217988; s9291; STK368476; AKOS000278000; Isopimpinellin (4,9-Dimethoxypsoralen); MCULE-5163280216; NSC-217988; NSC-401288; SDCCGMLS-0066520.P001; NCGC00095569-01; NCGC00095569-02; NCGC00095569-03; AK168165; BS-16832; NCI60_003765; SC-97796; SMR000440593; 4,9-Dimethoxy-7-oxofuro[3,2-g]chromene; 5,9-dimethoxyfurano[3,2-g]chromen-2-one; 4,9-Dimethoxyfuro[3,2-g]benzopyran-7-one; DB-051533; CS-0009794; FT-0603412; I0861; ST50308983; W1277; 5,9-dimethoxy-2H-furo[3,2-g]chromen-2-one; C02162; 4,9-Dimethoxy-7H-furo[3,2-g]chromen-7-one #; SR-01000778471; Q-100529; Q6086206; SR-01000778471-2; BRD-K72253829-001-02-8; BRD-K72253829-001-03-6; BRD-K72253829-001-07-7; 4,9-Dimethoxy-7H-furo[3,2-g][1]benzopyran-7-one, 9CI; NCGC00095569-05!4,9-dimethoxyfuro[3,2-g]chromen-7-one; 7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dimethoxy- (8CI)(9CI)
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
N-[(2S,3R)-4-[[(2S)-1-(Cyclohexylamino)-1-oxopropan-2-yl]-methylamino]-3-hydroxy-1-phenylbutan-2-yl]-3-methylsulfonylbenzamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL403087; BDBM50373798
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[30] | |||
| Compound Name |
2-(2-((4-Ethyl-8-methyl-2-oxo-2H-chromen-7-yloxy)carbonylamino)acetamido)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164314; BDBM50320638
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|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
2-{[N-(2-{[(Carboxyethyl)amino]carbonylamino}ethyl)carbamoyl]amino}propanoic a cid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164946; BDBM50320689; STK530204; AKOS005463003; MCULE-5773018723; ST000380; 2,11-dimethyl-4,9-dioxo-3,5,8,10-tetraazadodecane-1,12-dioic acid; 2,11-dimethyl-4,9-dioxo-3,5,8,10-tetraazadodecane-1,12-dioic acid (non-preferred name)
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Scoparone
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|
Investigative | Compound Info | ||
| Synonyms |
6,7-DIMETHOXYCOUMARIN; 6,7-Dimethylesculetin; Escoparone; Scoparon; Aesculetin dimethyl ether; 6,7-Dimethoxy-2-benzopyrone; Esculetin dimethyl ether; 6,7-Dimethoxy-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 6,7-dimethoxy-; 6,7-Dimethoxy-Coumarin; 6,7-dimethoxychromen-2-one; Scopoletin methyl ether; 6,7-Dimethoxybenzopyran-2-one; 6,7-Dimethoxy-2H-1-benzopyran-2-one; Dimethyl esculetin; o-Methylscopoletin; Coumarin, 6,7-dimethoxy-; UNII-H5841PDT4Y; o-Methylisoscopoletin; o,o-Dimethylesculetin; Esculetin 6,7-dimethyl ether; H5841PDT4Y; MFCD00006871; Benzopyran-2-one, 6,7-dimethoxy- (9CI); EINECS 204-369-0; BRN 0169572; Scoparin?; Dimethylaesculetin; Scoparone,(S); Benzopyran-2-one, 6,7-dimethoxy-; 6,7-Dimethylcoumarine; PubChem13307; 6,7-Dimethoxycoumarine; ACMC-20am0m; Maybridge4_003009; 5-18-03-00204 (Beilstein Handbook Reference); KSC241M7T; SCHEMBL240777; 6,7-Dimethoxy-chromen-2-one; 6,7-Dimethoxycoumarin, 98%; CHEMBL325864; MEGxp0_001422; ZINC2067; ACon1_002079; 6,7-Dimethoxy-Benzopyran-2-one; DTXSID10152640; HMS1529I17; BCP11533; HY-N0228; KS-00000W5Q; BDBM50361374; CCG-41207; s3613; STL193280; 6,7-Dimethoxy-2H-chromen-2-one #; AKOS000277541; MCULE-1591753422; 6,7-Dimethoxycoumarin pound>>Escoparone; AC-11197; AK168106; BS-14810; SC-46088; AB0019685; DB-041524; AM20020282; CS-0008271; FT-0603321; N2328; ST50319943; A14856; C09311; W-1779; 120S081; Q-100099; SR-01000631300-1; BRD-K16835051-001-01-2; BRD-K16835051-001-02-0; Q15424761
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
[(3S)-2,2-Dimethyl-8-oxo-3,4-dihydropyrano[3,2-g]chromen-3-yl] (E)-2-methylbut-2-enoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1631595; Decursinol Tiglate; ZINC265471; BDBM50361395
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
7H-Furo(3,2-g)(1)benzopyran-7-one, 4,9-dihydroxy-
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
5,8-Dihydroxypsoralen; 7H-Furo[3,2-g][1]benzopyran-7-one, 4,9-dihydroxy-; CHEMBL1934068; 4,9-dihydroxyfuro[3,2-g]chromen-7-one; 5?8-Dihydroxypsoralen; 5,8-Dihydroxyfurocoumarin; Psoralen, 5,8-dihydroxy-; 4,9-Dihydroxy-7H-furp(3,2-g)(1)benzopyran-7-one; SCHEMBL10319923; DTXSID60162436; ZINC6526115; BDBM50361382; 4,9-dihydroxy-furo[3,2-g]chromen-7-one; AM20020487; 4,9-Dihydroxy-7H-furo[3,2-g]chromen-7-one; 4,9-Dihydroxy-7H-furo[3,2-g]chromen-7-one #; 4,9-dihydroxy-7h-furo[3,2-g](1)benzopyran-7-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Cnidicin
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1710181; 4,9-bis(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one; 5,8-Diprenyloxypsoralen; MLS002472889; HMS2268M22; HY-N4207; BDBM50361392; ZINC13323006; SMR001397000; CS-0032431; 4,9-Bis((3-methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one
Click to Show/Hide
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
(R)-2-(2-(7-Hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetamido)-5-ureidopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163846; BDBM50320639; STL463538; ZINC11865459; AKOS016390255; MCULE-5455758360; N~5~-carbamoyl-N~2~-[(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine; N~5~-(aminocarbonyl)-N~2~-[(7-hydroxy-4,8-dimethyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine
Click to Show/Hide
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Decursinol
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Investigative | Compound Info | ||
| Synonyms |
(+)-Decursinol; UNII-UBI4YB704B; (S)-(+)-decursinol; UBI4YB704B; CHEMBL481657; Smirino; Smyrinol; SFE decursinol; (S)-7-hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one; Decursinol [INCI]; MLS002472906; SCHEMBL14105325; DTXSID70178008; HMS2192M06; BCP24688; HY-N4109; ZINC1026053; BDBM50259817; MFCD06636641; AKOS008901445; SMR001397017; CS-0032117; C09259; Q27068163; (S)-7-Hydroxy-8,8-dimethyl-7,8-dihydropyrano(3,2-g)chromen-2(6H)-one; 7-Hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one #; (7S)-7,8-dihydro-7-hydroxy-8,8-dimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-2-one; (7S)-7-hydroxy-8,8-dimethyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromen-2-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
3-(2-(4-(2-Hydroxyethylamino)-6-morpholino-1,3,5-triazin-2-yl)hydrazinyl)-3-phenylpropanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163712; BDBM50320631
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
N-(Aminocarbonyl)-N-[(5-hydroxy-4,7-dimethyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1163263; BDBM50320641; STL463486; ZINC11865442; AKOS016392233; MCULE-7805483758; (R)-2-(2-(5-hydroxy-4,7-dimethyl-2-oxo-2H-chromen-3-yl)acetamido)-5-ureidopentanoic acid; N~5~-carbamoyl-N~2~-[(5-hydroxy-4,7-dimethyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Seselin
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Investigative | Compound Info | ||
| Synonyms |
Amyrolin; Pyranocoumarin deriv.; 8,8-dimethylpyrano[2,3-f]chromen-2-one; UNII-5634E8957P; 8,8-Dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one; CHEMBL71358; 8,8-Dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-2-one; 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 8,8-dimethyl-; 5634E8957P; 3',4'-Di-O-(-)-Camphanoyl-(+)-cis-khellactone; 2H,8H-Benzo(1,2-b:3,4-b')dipyran-2-one, 8,8-dimethyl-; 8,8-Dimethyl-2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one; Sesalin; Seseline; Oprea1_187929; SCHEMBL8993385; CTK4J5797; DTXSID60200322; HMS1648A10; ZINC265504; BDBM50361397; AKOS000276897; MCULE-7289743021; 2',2'-dimethyl-3-pyreno[6'5:7,8]coumarin; C09312; 8,8-DIMETHYLPYRANO[2,3-H]CHROMEN-2-ONE; 8,8-Dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one #; Q27104968; 8,8-Dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one, 9CI; 2H-1-Benzopyran-6-acrylic acid, 5-hydroxy-2,2-dimethyl-, .delta.-lactone
Click to Show/Hide
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
3-Methyl-2-(2-(2-methyl-5-phenylfuran-3-carboxamido)acetamido)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164242; BDBM50320681; SR-01000363487; SR-01000363487-1
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||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
Lomatin
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Investigative | Compound Info | ||
| Synonyms |
9-Hydroxy-8,8-dimethyl-9,10-dihydro-8H-pyrano[2,3-f]chromen-2-one; Jatamansinol; 9-Hydroxy-8,8-dimethyl-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-2-one; 9-hydroxy-8,8-dimethyl-9,10-dihydropyrano[2,3-h][1]benzopyran-2-one; CHEMBL503137; 9-HYDROXY-8,8-DIMETHYL-9,10-DIHYDRO-2H,8H-PYRANO(2,3-F)CHROMEN-2-ONE; Spectrum_001508; SpecPlus_000910; Spectrum2_000735; Spectrum3_001638; Spectrum4_001857; Spectrum5_000394; Oprea1_062915; Oprea1_769350; BSPBio_003335; KBioGR_002295; KBioSS_001988; MLS001207443; DivK1c_007006; SPECTRUM1504158; SPBio_000690; MEGxp0_001426; SCHEMBL6273711; CHEMBL1414353; ACon1_000110; CTK7H3624; KBio1_001950; KBio2_001988; KBio2_004556; KBio2_007124; KBio3_002555; HMS2831N08; 9-hydroxy-8,8-dimethyl-9,10-dihydropyrano[2,3-h]chromen-2-one; BDBM50361398; CCG-40141; STK396309; AKOS000546641; MCULE-1996740143; SDCCGMLS-0066803.P001; NCGC00095689-01; NCGC00095689-02; NCGC00095689-03; SMR000504765; ST50000032; AB00053122-02; AB00813344-06; 9-hydroxy-8,8-dimethylpyrano[6,5-f]chroman-2-one; BRD-A19918940-001-03-6; Q27163407; 9-hydroxy-8,8-dimethyl-9,10-dihydro-pyrano[6,5-h]chromen-2-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Columbianetin
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Investigative | Compound Info | ||
| Synonyms |
(+)-columbianetin; (S)-Columbianetin; (8S)-8-(2-hydroxypropan-2-yl)-8,9-dihydrofuro[2,3-h]chromen-2-one; Dihydrooroselol; (8S)-8-(2-hydroxypropan-2-yl)-8,9-dihydro-2H-furo[2,3-h]chromen-2-one; (8S)-8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]1-benzopyran-2-one; MLS000574835; CHEMBL201152; SCHEMBL20356593; HMS2194A09; ZINC898179; HY-N0363; BDBM50361393; AKOS015896771; NCGC00247537-01; SMR000156216; CS-0008912; C19707; Q27225745; 8-(1-Hydroxy-1-methylethyl)-8,9-dihydro-2H-furo[2,3-H]chromen-2-one #; 2H-Furo(2,3-H)-1-Benzopyran-2-One,8,9-Dihydro-8-(1-Hydroxy-1-Methylethyl)-,(S)-
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|
||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Osthenol
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Investigative | Compound Info | ||
| Synonyms |
UNII-7X6RF2708X; 7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one; 7-hydroxy-8-prenylcoumarin; CHEMBL350475; 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one; 7X6RF2708X; 2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-butenyl)-; 7-Hydroxy-8-prenylcoumarin; NSC 625328; 8-prenylumbelliferone; SCHEMBL51013; MEGxp0_000219; ACon1_000810; 7-hydroxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one; DTXSID80197508; BCP24741; ZINC1618130; 7-hydroxy--2H-1-benzopyran-2-one; BDBM50240868; MFCD03427690; NSC625328; AKOS025402390; AC-8807; MCULE-1778235745; NSC-625328; 8-(3-methylbut-2-en-1-yl)umbelliferone; NCI60_007807; 7-hydroxy-8-(3-methyl-but-2-enyl)coumarin; FT-0777401; C18080; 7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one; BRD-K53399718-001-01-8; Q27155413; 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one, 9CI; NCGC00169337-02!7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Xanthotoxol
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|
Investigative | Compound Info | ||
| Synonyms |
8-Hydroxypsoralen; 8-Hydroxypsoralene; Psoralen, 8-hydroxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-hydroxy-; 8-Hydroxyfuranocoumarin; Xanthotoxol (6CI); XANTHOTOL; 9-Hydroxy-7H-furo[3,2-g]chromen-7-one; NSC 401269; 9-Hydroxy-7H-furo(3,2-g)(1)benzopyran-7-one; 9-hydroxyfuro[3,2-g]chromen-7-one; NSC401269; 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 7H-Furo(3,2-g)(1)benzopyran-7-one, 9-hydroxy-; 6,7-Dihydroxy-5-benzofuranacrylic acid gamma-lactone; EINECS 217-923-1; BRN 0189491; 8-hydroxy-psoralen; 8-Hydroxyanthotoxol; 8-hydroxyfurocoumarin; 8-hydroxyfurocoumarins; 9-hydroxy-furo[3,2-g]chromen-7-one; 8-hydroxyfuranocoumarins; an 8-hydroxyfurocoumarin; 7H-Furo[3, 9-hydroxy-; CHEMBL1192; 5-19-06-00014 (Beilstein Handbook Reference); 7H-Furo[3,2-g][1]benzopyran-7-one,9-hydroxy-; MLS002472938; SCHEMBL499269; 5-Benzofuranacrylic acid, 6,7-dihydroxy-, gamma-lactone; DTXSID50173910; HMS2267B05; HMS3886P18; ZINC895404; BDBM50361378; MFCD00017408; s9174; 9-hydroxyfurano[3,2-g]chromen-2-one; AKOS000276803; CCG-266594; CS-8023; MCULE-4145719408; NSC-401269; NCGC00247457-01; AC-12979; HY-30152; SMR001397046; 9-hydroxy-2H-furo[3,2-g]chromen-2-one; AB0021832; DB-045082; FT-0633974; N2298; ST50308995; W1288; 9-Hydroxy-7H-furo[3,2-g]chromen-7-one #; A14771; C00841; Q4021722; W-201757; 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one, 9CI; 5-Benzofuranacrylic acid, 6,7-dihydroxy-, .delta.-lactone; 5-Benzofuranacrylic acid, 6,7-dihydroxy-, gamma-lactone (7CI); 2-Propenoic acid,7-dihydroxy-5-benzofuranyl)-, .delta.-lactone; 6-(3,4-Dichlorophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole; 2-Propenoic acid, 3-(6,7-dihydroxy-5-benzofuranyl)-, .delta.-lactone
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Suberosin
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Investigative | Compound Info | ||
| Synonyms |
NSC31869; 2H-1-Benzopyran-2-one, 7-methoxy-6-(3-methyl-2-butenyl)-; Coumarin, 7-methoxy-6-(3-methyl-2-butenyl)-; 7-methoxy-6-(3-methylbut-2-enyl)chromen-2-one; CHEMBL1928409; 2H-1-Benzopyran-2-one, 7-methoxy-6-(3-methyl-2-butenyl)- (9CI); 7-Methoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one; NSC 31869; 7-methoxy-6-prenylcoumarin; MEGxp0_001424; SCHEMBL6273982; ACon1_000574; CTK5A7890; DTXSID20206820; HY-N1196; ZINC1664037; BDBM50361375; NSC-31869; AKOS028108564; MCULE-9562140872; NCI60_002737; CS-0016488; FT-0777160; W1275; Coumarin, 7-methoxy-6-(3-methyl-2-butenyl)- (8CI); Q27137382; 7-Methoxy-6-(3-methyl-2-butenyl)-2H-chromen-2-one #; 7-Methoxy-6-(3-methyl-2-buten-1-yl)-2H-chromen-2-one; NCGC00168948-02!7-methoxy-6-(3-methylbut-2-enyl)chromen-2-one
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
Osthole
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Investigative | Compound Info | ||
| Synonyms |
Osthol; Ostol; Ostole; 7-Methoxy-8-isopentenylcoumarin; 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one; NSC 31868; 8-(3-Methyl-2-butenyl)herniarin; 7-METHOXY-8-(3-METHYL-2-BUTENYL)-COUMARIN; 7-methoxy-8-(3-methyl-2-butenyl)coumarin; UNII-XH1TI1759C; Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-; CHEMBL52229; XH1TI1759C; NSC31868; 7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one; MFCD00076049; 7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one; SMR000156202; Osthole (Osthol); Osthole,(S); Cnidium Fruit Extract; Spectrum_001542; SpecPlus_000946; Spectrum2_000723; Spectrum3_001645; Spectrum4_001687; Spectrum5_000334; Osthole, analytical standard; Oprea1_642606; Oprea1_873803; SCHEMBL50436; BSPBio_003369; KBioGR_001954; KBioSS_002022; ZINC566; MLS000574904; MLS001048988; MLS006011425; DivK1c_007042; SPECTRUM1504165; SPBio_000646; MEGxp0_000155; ACon1_002155; CTK7A8592; GTPL10302; HSDB 8479; KBio1_001986; KBio2_002022; KBio2_004590; KBio2_007158; KBio3_002589; DTXSID20197507; HMS2267O21; HMS3656A07; BCP10832; EBD33224; HY-N0054; KS-00000N3A; ANW-50075; BBL013019; BDBM50240512; CCG-40172; CO0040; NSC-31868; s2337; STK396321; AKOS000277663; AC-8041; DS-0881; MCULE-5691054147; SDCCGMLS-0066780.P001; NCGC00095694-01; NCGC00095694-02; NCGC00095694-03; NCGC00095694-05; WLN: T66 BOVJ IO1 J2UY1&1; AK-35300; BR-35300; AB0021820; FT-0601535; N1825; O0426; ST50909221; SW219438-1; W1256; C09280; J10077; S-3211; 484O128; A827530; SR-01000721624; Q-100535; Q4338679; SR-01000721624-4; BRD-K78294846-001-03-3
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||||
| Activity |
IC50 > 500000 nM
|
[2] | |||
| Compound Name |
(R)-2-(2-(7-Hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetamido)-5-ureidopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164009; BDBM50320642; STL462740; ZINC11867572; AKOS016379141; MCULE-2652504518; N~5~-(aminocarbonyl)-N~2~-[(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine; N~5~-carbamoyl-N~2~-[(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetyl]-D-ornithine
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[9] | |||
| Compound Name |
2-Amino-6-[(1S,2R)-2-(3-bromophenyl)cyclopropyl]-3-methylpyrimidin-4-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169931; BDBM50397273
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|
||||
| Activity |
IC50 = 502000 nM
|
[16] | |||
| Compound Name |
(R)-3-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-benzylpentanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222141; BDBM50324914
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|
||||
| Activity |
IC50 = 516000 nM
|
[21] | |||
| Compound Name |
8-Bromoquinolin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1821798; SCHEMBL15228915; KS-00000SSK; DTXSID80652864; BDBM50351909; MFCD08062652; ZINC26474701; AKOS013528017; CM10275; MB05228; MCULE-6675524064; NE48937; AK164599; AS-41413; SC-68164; AB0039531; Y7011; J-519407; W-204686
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||||
| Activity |
IC50 = 562000 nM
|
[80] | |||
| Compound Name |
Aminopyrimidine, 12
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467216; BDBM26491; N-{5-[(6-phenylpyrimidin-4-yl)amino]-2-(prop-2-en-1-yl)phenyl}methanesulfonamide
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||||
| Activity |
IC50 = 570000 nM
|
[36] | |||
| Compound Name |
Aminopyrimidine, 11
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467003; BDBM26490; N-{2-phenyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}methanesulfonamide
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||||
| Activity |
IC50 > 600000 nM
|
[36] | |||
| Compound Name |
Aminopyrimidine, 15
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL444170; BDBM26494; N-{2-methyl-5-[(6-phenylpyrimidin-4-yl)amino]phenyl}acetamide
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||||
| Activity |
IC50 > 600000 nM
|
[36] | |||
| Compound Name |
Aminopyrimidine, 14
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466383; BDBM26493; 4-bromo-1-N-(6-phenylpyrimidin-4-yl)benzene-1,3-diamine
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||||
| Activity |
IC50 > 600000 nM
|
[36] | |||
| Compound Name |
N-(4-Bromo-3-nitrophenyl)-6-phenylpyrimidin-4-amine
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Investigative | Compound Info | ||
| Synonyms |
aminopyrimidine, 13; CHEMBL446536; BDBM26492
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|
||||
| Activity |
IC50 > 600000 nM
|
[36] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1S,2R)-2-(3-phenylphenyl)cyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169932; BDBM50397272
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|
||||
| Activity |
IC50 = 614000 nM
|
[16] | |||
| Compound Name |
2-Amino-3-methyl-6-[(1R,2S)-2-phenylcyclopropyl]pyrimidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2169927; BDBM50397277
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|
||||
| Activity |
IC50 = 619000 nM
|
[16] | |||
| Compound Name |
3,3-Dimethyl-N-[2-phenyl-1-(2H-tetrazol-5-yl)ethyl]-2,4-dihydroisoquinolin-1-imine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2346791; BDBM50432184
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|
||||
| Activity |
IC50 = 638600 nM
|
[40] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2R,3S)-1-[[(1S)-1-carboxybutyl]-methylamino]-2-hydroxy-5-methylhexan-3-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604700; BDBM50110897
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|
||||
| Activity |
IC50 = 680000 nM
|
[24] | |||
| Compound Name |
(S)-3-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-isopropylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1222236; BDBM50324918
Click to Show/Hide
|
||||
| Activity |
IC50 = 695000 nM
|
[21] | |||
| Compound Name |
1H-Benzimidazol-2-amine, 5-chloro-
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Investigative | Compound Info | ||
| Synonyms |
2-amino-6-chlorobenzimidazole; 6-chloro-1H-benzimidazol-2-amine; 2-Amino-5-chlorobenzimidazole; 5-Chloro-2-aminobenzimidazole; 5-Chloro-1H-benzoimidazol-2-ylamine; 5-chloro-1H-benzimidazol-2-amine; Benzimidazole, 2-amino-6-chloro-; BENZIMIDAZOLE, 2-AMINO-5-CHLORO-; 2-Amino-5-chloro-1H-benzimidazole; 1H-Benzimidazol-2-amine, 6-chloro-; 6-chloro-1H-benzo[d]imidazol-2-amine; MLS002638147; CHEMBL269158; 5-chloro-1H-benzo[d]imidazol-2-amine; 5-CHLORO-1H-1,3-BENZODIAZOL-2-AMINE; CCRIS 4359; NSC 10545; NSC10545; zlchem 891; PubChem7587; Oprea1_317702; Oprea1_834530; SCHEMBL216615; 2-amino-5-chloro-benzimidazole; 2-aminobenzimidazole deriv., 4; DTXSID1063857; BDBM31794; CTK4J9938; ZLD0352; HMS3080J07; 5-chloro-1h-benzimidazole-2-amine; ZINC5425419; 1H-Benzimidazol-2-amine,6-chloro-; 7788AB; ANW-57382; MFCD00749332; MFCD08234599; NSC-10545; AKOS000540719; AKOS015914093; AKOS025244158; AB07015; FS-1408; MCULE-4911467346; KS-0000257B; (5-chloro-1H-benzoimidazol-2-yl)-amine; SC-05205; SMR000734645; SY041922; DB-020490; 4-(1,3-DITHIOLAN-2-YL)BENZOICACID; FT-0635693; 5-Chloro-1H-benzimidazol-2-ylamine, AldrichCPR; 418C939; SR-01000396932; SR-01000396932-1; Q27467045; Z1741962130
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| Activity |
IC50 = 731000 nM
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[21] | |||
| Compound Name |
3-(2-Amino-5-chloro-1H-benzimidazol-1-yl)propan-1-ol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221922; HMS1592O17; ZINC4709834; BDBM50324898; STK213136; AKOS005417198; MCULE-6312589599; ST4128030; 3-(2-amino-5-chlorobenzimidazolyl)propan-1-ol; SR-01000272523; SR-01000272523-1; Q27460075; 3-(2-amino-5-chloro-1H-1,3-benzimidazol-1-yl)-1-propanol; 3-(2-amino-5-chloro-1H-1,3-benzodiazol-1-yl)propan-1-ol; 3-(2-amino-5-chloro-1H-benzo[d]imidazol-1-yl)propan-1-ol
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| Activity |
IC50 = 770000 nM
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[21] | |||
| Compound Name |
Ninhydrin
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Investigative | Compound Info | ||
| Synonyms |
Ninhydrine; Ninhydrin hydrate; 1H-Indene-1,3(2H)-dione, 2,2-dihydroxy-; 2,2-Dihydroxy-1H-indene-1,3(2H)-dione; 2,2-Dihydroxy-1,3-indandione; Triketohydrindene hydrate; 2,2-Dihydroxy-1,3-indanedione; 1,2,3-Indantrione, 2-hydrate; 2,2-Dihydroxyindane-1,3-dione; 2,2-dihydroxyindene-1,3-dione; Ninhydrin Spray; Trioxohydrindene monohydrate; UNII-HCL6S9K23A; MFCD00003791; Ninhydrin, ACS reagent; 1,3-Indandione, 2,2-dihydroxy-; 2,2-dihydroxy-2,3-dihydro-1H-indene-1,3-dione; HCL6S9K23A; CHEMBL1221925; Ninhydrin, spectrophotometric grade; CCRIS 4849; EINECS 207-618-1; BRN 1910963; 2,2-dihydroxy-2-hydrocyclopenta[1,2-a]benzene-1,3-dione; Ningidrin; nin-hydrin; AI3-04464; ninhydrin monohydrate; Ninhydrin ACS grade; zlchem 153; DSSTox_CID_5716; DSSTox_RID_77890; DSSTox_GSID_25716; Ninhydrin, AR, >=99%; SCHEMBL17986; 4-07-00-02786 (Beilstein Handbook Reference); MLS002454421; DTXSID7025716; CTK7H1849; ZLB0142; Ninhydrin, >=95.0% (UV); ZINC388306; ACT05788; ALBB-033740; HY-D0908; Tox21_200705; 1,2,3-Triketohydrindene Monohydrate; BBL012206; BDBM50324901; Ninhydrin, puriss. p.a., >=99%; SBB009147; STL163548; AKOS004906785; 1H-Indene-1,2,3, trione Monohydrate; 1H-Indene-1,2,3-trione, 2-hydrate; CS-W018489; MCULE-8190517984; NE10279; NCGC00091114-01; NCGC00091114-02; NCGC00091114-03; NCGC00258259-01; AC-11764; AS-14832; BP-11883; Ninhydrin, p.a., ACS reagent, 99.0%; SMR001372015; ST094931; Ninhydrin spray reagent, 0.2% in ethanol; Ninhydrin, SAJ special grade, >=98.0%; DB-051560; Ninhydrin, ACS reagent, >=98.0% (UV); FT-0632202; I0015; N0094; N0719; Ninhydrin, suitable for amino acid detection; 27828-EP2292592A1; 27828-EP2292628A2; 27828-EP2298767A1; 27828-EP2305671A1; 27828-EP2305808A1; 27828-EP2311842A2; 27828-EP2314587A1; AQ-911/40896973; Q421098; J-610068; Q-201472; Ninhydrin, ozone friendly ready to use spray for TLC; F0001-2517; Ninhydrin, >=98.0%, suitable for amino acid analysis
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| Activity |
IC50 = 776000 nM
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[21] | |||
| Compound Name |
4H-3,1-Benzothiazin-2-amine
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Investigative | Compound Info | ||
| Synonyms |
2-Amino-4H-3,1-benzothiazine; CHEMBL3261081; NSC139660; SCHEMBL3022267; CTK2I1028; DTXSID80300878; 4H-3,1-Benzothiazin-2-amine #; ACT02776; 2-Amino-4H-benz[d]-1,3-thiazine; 4H-Benzo[d][1,3]thiazin-2-amine; BDBM50012656; AKOS006373214; NSC-139660
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| Activity |
IC50 = 790000 nM
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[67] | |||
| Compound Name |
2-Aminoquinoline
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Investigative | Compound Info | ||
| Synonyms |
quinolin-2-amine; 2-Quinolinamine; Aminoquinoline; Quinolinamine; Quinoline, 2-amino-; quinolin-2-ylamine; 2-amino-quinoline; Fragment 19; UNII-GR9M8HW75Z; GR9M8HW75Z; CHEMBL61236; 2-quinolylamine; CCRIS 1677; EINECS 209-458-8; NSC 57739; NSC 58387; BRN 0113163; quinolimine; amino-quinoline; a-Aminoquinoline; 2-Quinolinylamine; 2-?Quinolinamine; quinoline-2-amine; 2-Aminoquinoline 1; PubChem5818; 2-Quinolinamine, 9CI; 2-Aminoquinoline, 97%; ACMC-1AH5U; 2-1H-QUINOLINIMINE; SCHEMBL38775; 5-22-10-00220 (Beilstein Handbook Reference); KSC223A9P; 2-imino-1,2-dihydroquinoline; SCHEMBL1146984; DTXSID2060381; BDBM14322; CTK1C3097; CTK4C1715; KS-00000FQW; HMS1719H05; ACT03947; BCP30417; NSC57739; NSC58387; ANW-32862; BBL100884; MFCD00038079; NSC-57739; NSC-58387; SBB051994; STL554678; ZINC19074717; AKOS000279069; CS-W007524; MCULE-9057285409; PS-4207; VQ10090; 2-Aminoquinoline pound>>2-Quinolinamine; NCGC00188269-01; AC-13271; AK-26798; BR-26798; SC-05494; DB-005975; fragment 2 (J. med. chem.,50,1116); A0417; AM20061864; FT-0632430; ST50409632; EN300-10204; S-1912; 22860-EP2286812A1; 22860-EP2295421A1; 22860-EP2308848A1; 22860-EP2315502A1; 22860-EP2371810A1; 22860-EP2371812A1; 580A223; A831703; AC-907/25014242; Q209310; J-400243; Z56347237
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| Activity |
IC50 = 800000 nM
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[80] | |||
| Compound Name |
4-(2-Amino-5-chloro-1H-benzo[d]imidazol-1-yl)-N-(2-morpholinoethyl)butanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221979; BDBM50324905
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| Activity |
IC50 = 827000 nM
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[21] | |||
| Compound Name |
3-(3-Chlorophenyl)imidazo[1,2-a]pyrimidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221923; BDBM50324899
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| Activity |
IC50 = 862000 nM
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[21] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2S,3S)-4-[[(1S)-1-carboxybutyl]amino]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604696; BDBM50110900
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| Activity |
IC50 = 870000 nM
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[24] | |||
| Compound Name |
(4S)-4-Amino-5-[[(2S,3S)-1-[[(2S)-1-[[(2S,3S)-4-[[(1S)-1-carboxybutyl]amino]-3-hydroxy-4-oxo-1-thiophen-2-ylbutan-2-yl]amino]-1-oxo-3-thiophen-2-ylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3604603; BDBM50110903
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| Activity |
IC50 = 870000 nM
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[24] | |||
| Compound Name |
1-Methoxy-2-phenyl-1H-imidazo[4,5-b]pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221921; Oprea1_641259; MLS001165517; SCHEMBL12326600; KS-00003CFL; HMS2855C12; ZINC1396600; BDBM50324897; MFCD00141251; AKOS015993303; 7F-377S; MCULE-1390678396; SMR000549463
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| Activity |
IC50 = 928000 nM
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[21] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
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| REF 32 | Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. J Med Chem. 2010 Jan 14;53(1):52-60. | ||||
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| REF 40 | Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2181-6. | ||||
| REF 41 | Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, -Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation. J Med Chem. 2018 May 24;61(10):4476-4504. | ||||
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| REF 46 | US patent application no. 8933221B2, Hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds | ||||
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| REF 60 | Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3457-60. | ||||
| REF 61 | New aminoimidazoles as -secretase (BACE-1) inhibitors showing amyloid- (A) lowering in brain. J Med Chem. 2012 Nov 8;55(21):9297-311. | ||||
| REF 62 | Tyramine fragment binding to BACE-1. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1304-7. | ||||
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| REF 66 | Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6034-9. | ||||
| REF 67 | The evolution of amidine-based brain penetrant BACE1 inhibitors. Bioorg Med Chem Lett. 2014 May 1;24(9):2033-45. | ||||
| REF 68 | Discovery of cyclic sulfoxide hydroxyethylamines as potent and selective beta-site APP-cleaving enzyme 1 (BACE1) inhibitors: structure based design and in vivo reduction of amyloid beta-peptides. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5300-6. | ||||
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| REF 71 | Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands. J Med Chem. 2007 May 17;50(10):2399-407. | ||||
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| REF 73 | Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences. J Med Chem. 2017 Dec 14;60(23):9807-9820. | ||||
| REF 74 | Discovery of aminoheterocycles as a novel beta-secretase inhibitor class: pH dependence on binding activity part 1. Bioorg Med Chem Lett. 2009 Jun 1;19(11):2977-80. | ||||
| REF 75 | Dose-dependent inhibition of BACE-1 by the monoterpenoid 2,3,4,4-tetramethyl-5-methylenecyclopent-2-enone in cellular and mouse models of Alzheimer's disease. J Nat Prod. 2014 Jun 27;77(6):1275-9. | ||||
| REF 76 | Synthesis and evaluation of curcumin derivatives toward an inhibitor of beta-site amyloid precursor protein cleaving enzyme 1. Bioorg Med Chem Lett. 2014 Jan 15;24(2):685-90. | ||||
| REF 77 | Application of fragment-based NMR screening, X-ray crystallography, structure-based design, and focused chemical library design to identify novel microM leads for the development of nM BACE-1 (beta-site APP cleaving enzyme 1) inhibitors. J Med Chem. 2010 Feb 11;53(3):942-50. | ||||
| REF 78 | Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3075-80. | ||||
| REF 79 | Discovery of cell-permeable non-peptide inhibitors of beta-secretase by high-throughput docking and continuum electrostatics calculations. J Med Chem. 2005 Aug 11;48(16):5108-11. | ||||
| REF 80 | From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1). J Med Chem. 2011 Aug 25;54(16):5836-57. | ||||
| REF 81 | US patent application no. 9085576B2, Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use | ||||
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