Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T83611 | Target Info | |||
| Target Name | MHC class II antigen DRB1*1 (HLA-DRB1) | ||||
| Synonyms |
HLA class II histocompatibility antigen, DRB1-1 beta chain; DR1; DR-1
Click to Show/Hide
|
||||
| Target Type | Successful Target | ||||
| Gene Name | HLA-DRB1 | ||||
| Biochemical Class | MHC class II | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 8 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
((S)-3-Benzylsulfanyl-1-{(S)-1-[(S)-1-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-propyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80978; BDBM50289268
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
(S)-3-{(S)-2-[(S)-2-((S)-2-Ethoxycarbonylamino-3-phenyl-propionylamino)-3-methyl-butyrylamino]-propionylamino}-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418908; BDBM50289290
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
((R)-3-Benzylsulfanyl-1-{1-[1-(1-carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-propyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2369843; BDBM50289288
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
((S)-1-{(S)-5-Amino-1-[(S)-1-(1-carbamoyl-1-methyl-ethylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78827; BDBM50289249
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
((S)-1-{(S)-1-[(S)-1-((S)-1-Carbamoyl-2-phenyl-ethylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80428; BDBM50289254
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
((S)-1-{(S)-5-Amino-1-[(S)-1-((S)-4-amino-1-carbamoyl-butylcarbamoyl)-ethylcarbamoyl]-pentylcarbamoyl}-2-phenyl-ethyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79048; BDBM50289273
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
((S)-1-{(S)-1-[(S)-1-((S)-1-Carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-2-phenyl-ethyl)-carbamic acid 9H-fluoren-9-ylmethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL312435; BDBM50289250
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
((R)-{(S)-1-[(S)-1-((S)-1-Carbamoyl-3-methyl-butylcarbamoyl)-ethylcarbamoyl]-2-methyl-propylcarbamoyl}-phenyl-methyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76717; BDBM50289263
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | SAR for MHC class II binding tetrapeptides: Correlation with potential binding site. Bioorg Med Chem Lett. 1997 Jan 7;7(1):19-24. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.