Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T83904 | Target Info | |||
| Target Name | NAD-dependent deacetylase sirtuin-2 (SIRT2) | ||||
| Synonyms |
SIR2like protein 2; SIR2L2; SIR2L; SIR2-like protein 2; Regulatory protein SIR2 homolog 2; NADdependent protein deacetylase sirtuin2; NAD-dependent protein deacetylase sirtuin-2
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| Target Type | Patented-recorded Target | ||||
| Gene Name | SIRT2 | ||||
| Biochemical Class | Carbon-nitrogen hydrolase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 164 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
CAMBINOL
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Patented | Compound Info | ||
| Synonyms |
cambinol; 14513-15-6; SIRT1/2 Inhibitor IV, Cambinol; NSC112546; NSC-112546; NSC-1125476; 5-[(2-hydroxy-1-naphthyl)methyl]-2-mercapto-6-phenyl-4(3H)-Pyrimidinone; 5-(2-Hydroxynaphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one; 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one; Tetrahydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-Pyrimidinone; AC1MMYEF; NCIStruc2_001159; NCIStruc1_001428; SCHEMBL2538372; CHEMBL491960; CTK8G3107; BDBM29040
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| Activity |
IC50 = 51000 nM
|
[1] | |||
| Compound Name |
KENPAULLONE
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Patented | Compound Info | ||
| Synonyms |
kenpaullone; 142273-20-9; 9-Bromopaullone; NSC 664704; 9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one; NSC-664704; NSC664704; MLS002702152; CHEMBL296586; 9-Bromo-7,12-dihydroindolo(3,2-d)(1)benzazepin-6(5H)-one; Indolo[3,2-d][1]benzazepin-6(5H)-one,9-bromo-7,12-dihydro-; QQUXFYAWXPMDOE-UHFFFAOYSA-N; 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one; 9-bromo-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one; 9-Bromo-7,12-dihydro-indolo-[3,2-d]-[1]benzazepin-6(5H)-one
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
PMID28460551-Compound-2
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Patented | Compound Info | ||
| Activity |
IC50 = 122700 nM
|
[3] | |||
| Compound Name |
diphenylamine-2-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
N-phenylanthranilic acid; fenamic acid
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| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
G6976
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Investigative | Compound Info | ||
| Synonyms |
12H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-; Go 6976; 136194-77-9; GO6976; Go-6976; Goe 6976; UNII-B9IQO7JZ16; 6976; Go 6976, Solution; B9IQO7JZ16; 5,6,7,13-Tetrahydro-13-Methyl-5-oxo-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile; CHEMBL302449; CHEBI:51913; 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole; 12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole; Go6976
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
splitomicin
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Investigative | Compound Info | ||
| Synonyms |
splitomicin; 5690-03-9; 1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one; 1,2-dihydro-3h-benzo[f]chromen-3-one; 1H-benzo[f]chromen-3(2H)-one; CHEMBL86537; CHEBI:75272; 1,2-dihydrobenzo[f]chromen-3-one; 1H,2H,3H-naphtho[2,1-b]pyran-3-one; Splitomycin; Bio2_000878; Tocris-1542; AC1L1JZ6; AC1Q6ML4; KBioGR_000456; BSPBio_001116; KBioSS_000456; GTPL8101; SCHEMBL2544804; ZINC27374; KBio3_000852; KBio2_003024; BDBM29590; KBio3_000851; KBio2_005592; KBio2_000456; MolPort-003-959-546; ISFPDBUKMJDAJH-UHFFFAOYSA-N; HMS1362H17; HMS1990H17; Bio2_000398
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| Activity |
IC50 = 112900 nM
|
[5] | |||
| Compound Name |
N-(2-(1-(Thieno[3,2-d]pyrimidin-4-yl)piperidin-4-yl)ethyl)pivalamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2338821; SCHEMBL16023502; BDBM50431098; ZINC95591886; DA-27476; 2,2-dimethyl-N-[2-(1-thieno[3,2-d]pyrimidin-4-ylpiperidin-4-yl)ethyl]propanamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-Cyano-N-(quinolin-8-yl)-3-(5-(3-(trifluoromethyl)phenyl)furan-2-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225914; SCHEMBL10065537; DTXSID70360825; ZINC943066; SMSF0008510; BDBM50216687; AKOS001021423; CB00298; ST50077821; F0344-1620
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
3-(5-(2-Chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-8-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225971; (E)-3-(5-(2-chlorophenyl)furan-2-yl)-2-cyano-N-(quinolin-8-yl)acrylamide; ZINC943061; BDBM50216686; AKOS002185214; ST50077790; F0344-1610; (2E)-3-[5-(2-chlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
18-(1,2-Dihydroxyethyl)-26-fluoro-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^{7,14}.0^{2,6}.0^{8,13}.0^{22,27}]nonacosa-1(28),2(6),7(29),8,10,12,22(27),23,25-nonaene-3,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL384535; BDBM50199958
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
4-Chlorothieno[3,2-d]pyrimidine-6-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2332049; MFCD28098923; SCHEMBL16011549; BDBM50431110; ZINC95587098; BS-15119; DA-39503; SY265452; FT-0767097; Thieno[3,2-d]pyrimidine-6-carboxamide, 4-chloro-
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-(1-(2-(1H-Indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL242867; BDBM50241185; (E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)acrylamide
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| Activity |
IC50 = 50000 nM
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[8] | |||
| Compound Name |
(18R,19R)-18-[(Dimethylamino)methyl]-19,26-difluoro-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^{7,14}.0^{2,6}.0^{8,13}.0^{22,27}]nonacosa-1(28),2(6),7(29),8,10,12,22(27),23,25-nonaene-3,5-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL218377; BDBM50199959
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| Activity |
IC50 ~ 50000 nM
|
[2] | |||
| Compound Name |
2-Cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(quinolin-8-yl)acrylamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226027; SMSF0008553; ZINC1751305; BDBM50216690; AKOS002185154; CB00152; ST50077753; (2E)-3-[5-(2,3-dichlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
4-[4-[2-(2,2-Dimethylpropanoylamino)ethyl]piperidin-1-yl]thieno[3,2-d]pyrimidine-6-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2338819; SCHEMBL16023441; BDBM50431100; ZINC95591497; DA-21541
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
SIRT2 Inhibitor, Inactive Control, AGK7
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL226026; SMSF0008496; ZINC1220115; BDBM50216692; AKOS002185363; CB00296; ST50077772; J-017985; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-8-yl)acrylamide; (2E)-3-[5-(2,5-dichlorophenyl)(2-furyl)]-2-cyano-N-(8-quinolyl)prop-2-enamide; 2-Propenamide, 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-8-quinolinyl-
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| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-4-methoxybenzamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945258; SCHEMBL1706823
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| Activity |
IC50 = 50600 nM
|
[9] | |||
| Compound Name |
5-[(2-Hydroxynaphthalen-1-yl)methyl]-6-(2-phenylethyl)-2-sulfanylidene-1H-pyrimidin-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797748; BDBM50346537
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| Activity |
IC50 = 50800 nM
|
[10] | |||
| Compound Name |
4-(3-(4-(4-Fluorobenzyloxy)phenyl)acrylamido)-N-(2-(5-fluoro-1H-indol-3-yl)ethyl)piperidine-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL215918; BDBM50199445; AB00037964-01
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| Activity |
IC50 = 51000 nM
|
[8] | |||
| Compound Name |
Ethyl N-[4-[(3-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090805; BDBM50267627
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| Activity |
IC50 = 51100 nM
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[11] | |||
| Compound Name |
[[(2R,3S,4R,5R)-5-[6-Amino-8-(4-methylphenyl)purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3350588
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| Activity |
IC50 = 52000 nM
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[12] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-3,4,5-trifluorobenzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3969622; BDBM235914; US9365508, D1 (3,4,5-F3)
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| Activity |
IC50 = 52500 nM
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[13] | |||
| Compound Name |
Ethyl 2-[4-(dimethylamino)phenyl]-1-[3-(2-oxopyrrolidin-1-yl)propyl]benzimidazole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290210; BDBM50021512
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| Activity |
IC50 = 52780 nM
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[14] | |||
| Compound Name |
Ethyl 2-(4-morpholinophenyl)-1H-benzimidazole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3752305
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| Activity |
IC50 = 52910 nM
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[15] | |||
| Compound Name |
(2S)-2-[[(2S)-6-(Ethanethioylamino)-2-[3-(2-hydroxyphenyl)propanoylamino]hexanoyl]amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835307; BDBM50355049
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| Activity |
IC50 = 53000 nM
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[16] | |||
| Compound Name |
Sirtinol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL380797; 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide; 2-{[(2-hydroxy-1-naphthyl)methylene]amino}-N-(1-phenylethyl)benzamide; (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-[[(Z)-(2-oxonaphthalen-1-ylidene)methyl]amino]-N-(1-phenylethyl)benzamide; 2-[(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino]-N-(1-phenylethyl)benzamide; 2-[(2-oxo-1-naphthalenylidene)methylamino]-N-(1-phenylethyl)benzamide; 2-[(2-hydroxynaphthalen-1-yl)methylideneamino]-N-(1-phenylethyl)benzamide; 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide; Sir Two Inhibitor Naphthol; 2-[(2-oxonaphthalen-1-ylidene)methylamino]-N-[(1R)-1-phenylethyl]benzamide; Probes1_000047; Probes1_000316; Probes2_000084; Probes2_000518; Oprea1_639422; CBDivE_000728; ARONIS007637; SCHEMBL2543371; SCHEMBL8227466; Sirtinol, >=95% (NMR); KS-00003ZNW; HMS3413N18; HMS3651B13; HMS3677N18; BCP22454; EX-A4220; BDBM50156760; MFCD00810186; s2804; STL069068; AKOS000497157; AKOS016842267; AKOS030627556; AB07334; CCG-265000; CS-5291; DS-0089; MCULE-8856934531; Sirtinol - CAS 410536-97-9; VZ23394; SMP2_000018; AC-32747; AK-16605; BR-16605; HY-13515; BCP0726000065; FT-0644594; SW219185-1; W6155; S-5353; BRD-A23747351-001-01-9; Q27140353; Q27215793; 2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide; 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl) benzamide; (E)-2-(((2-HYDROXYNAPHTHALEN-1-YL)METHYLENE)AMINO)-N-(1-PHENYLETHYL)BENZAMIDE; 2-[(2-hydroxy-naphthalen-1-ylmethylene)-amino]-N-(1-phenyl-ethyl)-benzamide; 2-[[(2-HYDROXY-1-NAPHTHALENYL)METHYLENE]AMINO]-N-(1-PHENYLETHYL)BENZAMIDE; 2-{[(E)-(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-(1-phenylethyl)benzamide
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| Activity |
IC50 = 53000 nM
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[17] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]piperidine-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152598; BDBM50392096
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| Activity |
IC50 = 53000 nM
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[4] | |||
| Compound Name |
2-(3-Benzyloxyphenylamino)Benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152612; BDBM50392110
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| Activity |
IC50 = 54000 nM
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[4] | |||
| Compound Name |
(2S)-2-[[(2S)-6-(Ethanethioylamino)-2-(3-phenylpropanoylamino)hexanoyl]amino]propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835305; BDBM50355046
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| Activity |
IC50 = 56000 nM
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[16] | |||
| Compound Name |
Ethyl 2-(1,3-benzodioxol-5-yl)-1-(2-hydroxyethyl)benzimidazole-5-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105182; BDBM50445821
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| Activity |
IC50 = 56050 nM
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[18] | |||
| Compound Name |
1,4-Bis[2-(4-hydroxyphenyl)ethylamino]anthracene-9,10-dione
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Investigative | Compound Info | ||
| Synonyms |
JFD00244; BML-266; 1,4-BIS[(P-HYDROXYPHENETHYL)AMINO]-ANTHRAQUINONE; CHEMBL425294; SCHEMBL3886741; CTK8E3136; AOB2882; DTXSID20384692; HMS3261L04; ZINC3820899; Tox21_500611; 9,10-Anthracenedione, 1,4-bis[[2-(4-hydroxyphenyl)ethyl]amino]-; BDBM50156763; CCG-41282; MFCD00208443; LP00611; SDCCGSBI-0633736.P001; NCGC00186017-01; NCGC00186017-05; NCGC00261296-01; AS-16734; HY-108986; CS-0033891; JFD00244, >=98% (HPLC), solid; 1,4-bis[2-(p-hydroxyphenyl)ethylamino]anthraquinone; SR-01000631372-1; 1,4-bis[2-(4-hydroxyphenyl)ethylamino]anthraquinone; 1,4-bis[2-(p-hydroxyphenyl)ethylamino] anthraquinone; BRD-K93300946-001-01-2; Q27216285; 1,4-bis(4-hydroxyphenethylamino)anthracene-9,10-dione
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| Activity |
IC50 = 56700 nM
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[19] | |||
| Compound Name |
1-[[3-(4-Tert-butylphenyl)-1,2,4-oxadiazole-5-carbonyl]amino]-3-[3-(trifluoromethyl)phenyl]thiourea
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL512966; SCHEMBL2542137; BDBM50261974; CCG-42491; SR-01000632487-1; 3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]thiourea
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| Activity |
IC50 = 57000 nM
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[20] | |||
| Compound Name |
2-(3-Benzamidophenylamino)Benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152606; BDBM50392104
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| Activity |
IC50 = 57000 nM
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[4] | |||
| Compound Name |
N-(1H-1,2,4-Triazole-3-yl)-3-(naphthalene-2-yl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3358389; BDBM50041527
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| Activity |
IC50 = 57000 nM
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[21] | |||
| Compound Name |
(2S)-N-[(2S)-5-Acetamido-1-amino-1-oxopentan-2-yl]-6-(carbamothioylamino)-2-[[(2S)-2,5-diacetamidopentanoyl]amino]hexanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814814; BDBM50350509
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| Activity |
IC50 = 57200 nM
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[22] | |||
| Compound Name |
Benzyl N-[(2S)-1-(cyclohexylamino)-6-(ethanethioylamino)-1-oxohexan-2-yl]carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835309; BDBM50355050
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| Activity |
IC50 = 57200 nM
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[16] | |||
| Compound Name |
N,N'-Bis(salicylidene)-p-phenylenediamine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL373990; NSC1146; Enamine_004951; CBDivE_003670; SCHEMBL2494083; CTK1H1157; HMS1408B01; bis(salicylidene)-p-phenylenediamine; NSC-1146; NSC49134; Di-N-salicylidene-p-phenylenediamine; BDBM50201112; NSC-49134; ZINC16891020; Bis(salicylidene)-1,4-benzenediamine; N,N'-p-Phenylenebis(salicylaldimine); AKOS000508231; AKOS030661443; N,N'-Disalicylidene-p-phenylenediamine; ZINC103610572; ZINC103610575; MCULE-3850342772; IDI1_007538; o-Cresol, a,a'-(p-phenylenedinitrilo)di-; ST50550278; alpha,alpha'-(p-Phenylenedinitrilo)di-o-cresol; 1,4-DI(2-HYDROXYBENZYLIDENEAMINO)BENZENE; N,N''-bis(2-hydroxybenzylidene)benzene1,4diamine; N,N'-Bis(O-hydroxybenzylidene)-p-phenylenediamine; Phenol, 2,2'-[1,4-phenylenebis(nitrilomethylidyne)]bis-; N,N'-BIS(2-HYDROXYBENZYLIDENE)-1,4-PHENYLENEDIAMINE; 2,2',2,2'-[p-Phenylenebis(iminomethylidyne)]bis[3,5-cyclohexadiene-1-one]; 2-[(E)-[4-[(E)-(2-hydroxyphenyl)methyleneamino]phenyl]iminomethyl]phenol; 2-((1E)-2-{4-[(1E)-2-(2-hydroxyphenyl)-1-azavinyl]phenyl}-2-azavinyl)phenol
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| Activity |
IC50 = 58400 nM
|
[19] | |||
| Compound Name |
15-Cyclohexyl-11-oxa-13,15-diazatetracyclo[8.8.0.02,7.012,17]octadeca-1(10),2,4,6,8,12,17-heptaene-14,16-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2171196; BDBM50397033
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| Activity |
IC50 = 58500 nM
|
[23] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-2-acetamidopropanoyl]amino]-N-[(2S)-1-(methylamino)-1-oxopropan-2-yl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254217; BDBM50326786; (S)-6-Acetamido-2-((S)-2-acetamidopropanamido)-N-((S)-1-(methylamino)-1-oxopropan-2-yl)hexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[24] | |||
| Compound Name |
2-(P-Tolylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152573; 2-(4-methylanilino)benzamide; SCHEMBL15688476; BDBM50392069
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[4] | |||
| Compound Name |
Ethyl 1-(2-hydroxyethyl)-2-(4-piperidin-1-ylphenyl)benzimidazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3105181; BDBM50445822
Click to Show/Hide
|
||||
| Activity |
IC50 = 60340 nM
|
[18] | |||
| Compound Name |
1-Phenyl-2-(4-methylphenyl)-1H-benzoimidazole-5-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3290220; BDBM50021528
Click to Show/Hide
|
||||
| Activity |
IC50 = 60600 nM
|
[14] | |||
| Compound Name |
N-(2-(1H-Indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244160; BDBM50241183; (E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)phenyl)acrylamido)piperidine-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[8] | |||
| Compound Name |
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N-[5-(naphthalen-2-ylmethyl)-1,3-thiazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770486; BDBM50148800
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[25] | |||
| Compound Name |
Ethyl 3-[[(5S)-6-anilino-6-oxo-5-(phenylmethoxycarbonylamino)hexyl]amino]-3-oxopropanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2170193; BDBM50396055
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[26] | |||
| Compound Name |
(2S)-2-[[(2S)-2-Acetamidopropanoyl]amino]-6-(2,2-dimethylpropanoylamino)-N-[(2S)-1-(methylamino)-1-oxopropan-2-yl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254304; BDBM50326785; (S)-2-((S)-2-Acetamidopropanamido)-N-((S)-1-(methylamino)-1-oxopropan-2-yl)-6-pivalamidohexanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[24] | |||
| Compound Name |
4-[(2-Chloro-6-hydroxyquinolin-5-yl)methyl]-5-(4-propan-2-ylphenyl)-1,2-dihydropyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233748; BDBM50004795
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[1] | |||
| Compound Name |
2-(4-(Trifluoromethyl)Phenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152574; SCHEMBL22571369; BDBM50392070
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[4] | |||
| Compound Name |
2-[4-[Methyl(phenyl)carbamoyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152591; BDBM50392089
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[4] | |||
| Compound Name |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-(3-methylbut-2-enamido)hexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254380; BDBM50326787
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[24] | |||
| Compound Name |
Chembl4161556
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449715
Click to Show/Hide
|
||||
| Activity |
IC50 = 70600 nM
|
[27] | |||
| Compound Name |
2-(M-Tolylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(3-Tolyamino)benzamide; CHEMBL560337; BDBM50297160
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[4] | |||
| Compound Name |
Ser-Asp-Lys(epsilon-thioAc)Ala-Ile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523498; BDBM50257349
Click to Show/Hide
|
||||
| Activity |
IC50 = 72800 nM
|
[28] | |||
| Compound Name |
3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[4-trifluoromethylphenyl]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466754; BDBM50261757
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[20] | |||
| Compound Name |
2-Anilinobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(phenylamino)benzamide; Benzamide, 2-(phenylamino)-; Benzamide, o-anilino-; CHEMBL561194; BRN 0782669; Anilinobenzamide; NSC75183; 2-Phenylaminobenzamide; 2-phenylamino-benzamide; 3-14-00-00903 (Beilstein Handbook Reference); ARONIS26963; SCHEMBL1318994; DTXSID50153151; KUC112561N; BENZAMIDE,2-(PHENYLAMINO)-; KS-00000S3U; KS-000048GW; ZINC1674116; BDBM50297159; MFCD00476529; NSC-75183; AKOS005279221; DS-8370; MCULE-6691808486; KSC-321-003; AK145944; DS-009752; BRD-K79647146-001-01-2
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[29] | |||
| Compound Name |
2,4-Dichloro-6-[[2-[[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methylsulfanyl]anilino]methylidene]cyclohexa-2,4-dien-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220458; Maybridge3_000907; SCHEMBL3896710; HMS1433J05; BDBM50156759; ZINC100065893; MCULE-9941367326; IDI1_012294
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[30] | |||
| Compound Name |
2-[3-[(2-Phenylacetyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152608; BDBM50392106
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[4] | |||
| Compound Name |
Chembl4174893
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449696
Click to Show/Hide
|
||||
| Activity |
IC50 = 75857.76 nM
|
[27] | |||
| Compound Name |
(S)-2-((S)-2-((S)-2-Acetamidopropanamido)-6-(3-methylbut-2-enamido)hexanamido)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254459; BDBM50326783
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[24] | |||
| Compound Name |
2-(4-Acetamidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152595; BDBM50392093
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[4] | |||
| Compound Name |
11-Methyl-3-nitro-5,6-dihydrobenzo[b][1]benzazepine-8-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3222156; BDBM50496765
Click to Show/Hide
|
||||
| Activity |
IC50 = 77500 nM
|
[31] | |||
| Compound Name |
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770474; BDBM50148774; AKOS008348493
Click to Show/Hide
|
||||
| Activity |
IC50 = 77800 nM
|
[25] | |||
| Compound Name |
3,4-Bis(1-benzyl-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL384899; BDBM50199956
Click to Show/Hide
|
||||
| Activity |
IC50 = 78300 nM
|
[2] | |||
| Compound Name |
2-(4-Methoxyanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152576; 2-(4-Methoxyphenylamino)Benzamide; SCHEMBL6443532; CTK0E6090; DTXSID20542497; BDBM50392073; Benzamide, 2-[(4-methoxyphenyl)amino]-
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[4] | |||
| Compound Name |
N-(1-(2-(5-Fluoro-1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-hydroxyphenyl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL245011; BDBM50241187
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[8] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-2-methylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945670; CHEMBL1962976; BDBM50363785
Click to Show/Hide
|
||||
| Activity |
IC50 = 80700 nM
|
[13] | |||
| Compound Name |
2-[3-(Phenylcarbamoyl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152602; BDBM50392100
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[4] | |||
| Compound Name |
Methyl 4-(2-Carbamoylphenylamino)Benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152579; BDBM50392076
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[4] | |||
| Compound Name |
2-Methyl-8-(3-methylphenyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408824; BDBM50070586
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[32] | |||
| Compound Name |
Asp-Lys(epsilon-thioAc)-Thr-Ile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493160; BDBM50257237
Click to Show/Hide
|
||||
| Activity |
IC50 = 83400 nM
|
[28] | |||
| Compound Name |
Ser-Asp-Lys(epsilon-thioAc)Thr-Ala
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492521; BDBM50257404
Click to Show/Hide
|
||||
| Activity |
IC50 = 84600 nM
|
[28] | |||
| Compound Name |
2,4-Dioxo-N-[3-(2-pyridin-4-ylethyl)phenyl]-1H-quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622696; SCHEMBL16179957; BDBM50123364; ZINC19330730; AKOS030459960
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[33] | |||
| Compound Name |
N-{(S)-1-[2-(5-Benzyloxy-1H-indol-3-yl)-ethylcarbamoyl]-ethyl}-3-phenyl-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL488685; BDBM50245055
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[8] | |||
| Compound Name |
Bauerine C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7,8-dichloro-9-methyl-2H-pyrido[3,4-b]indol-1-one; CHEMBL474872; MLS005148197; SCHEMBL17867404; SCHEMBL18134620; DTXSID00166079; ZINC5116651; 7,8-Dichloro-2,9-dihydro-9-methyl-1H-pyrido(3,4-b)indol-1-one; BDBM50303772; SMR003965432; 7,8-dichloro-1-hydroxy-9-methyl-beta-carboline; 1H-Pyrido(3,4-b)indol-1-one, 7,8-dichloro-2,9-dihydro-9-methyl-
Click to Show/Hide
|
||||
| Activity |
IC50 = 87200 nM
|
[3] | |||
| Compound Name |
2-(4-Phenethylphenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152590; BDBM50392088
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[4] | |||
| Compound Name |
4-Tert-butyl-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamoyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945672; SCHEMBL907138; 5-dimethylamino-pentanoic acid {4-[3-(4-tert-butyl-benzoyl)-ureido]-phenyl}-amide hydrochloride
Click to Show/Hide
|
||||
| Activity |
IC50 = 88400 nM
|
[9] | |||
| Compound Name |
Chembl4170003
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449728
Click to Show/Hide
|
||||
| Activity |
IC50 = 89125.09 nM
|
[27] | |||
| Compound Name |
4-Tert-butyl-N-[[4-[[2-[2-[2-[2-[2-[2-(dimethylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetyl]amino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945134; SCHEMBL907374
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
US9365508, C6 (3-CF3,
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986268; BDBM235913
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[13] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-3-methylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945261
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]-4-methylbenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945257; SCHEMBL1707948
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
4-Chloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945259; SCHEMBL1707510
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
2-Chloro-N-[[4-[5-(dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945671; SCHEMBL1706965
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
Cambinol analog, 6b
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521799; SCHEMBL1711571; BDBM29042; 6-(4-bromophenyl)-5-[(2-hydroxynaphthalen-1-yl)methyl]-2-sulfanylidene-1H-pyrimidin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[34] | |||
| Compound Name |
N-[[4-[5-(Dimethylamino)pentanoylamino]phenyl]carbamothioyl]benzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945256; SCHEMBL1707575
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[9] | |||
| Compound Name |
2-[[3-[[2-Hydroxy-3-(hydroxymethyl)phenyl]methylideneamino]-5-(trifluoromethyl)phenyl]iminomethyl]-6-(hydroxymethyl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL386248; BDBM50199448; CD-03241
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[35] | |||
| Compound Name |
Ser-Asp-Lys(epsilon-thioAc)Leu-Met
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447852; BDBM50257346
Click to Show/Hide
|
||||
| Activity |
IC50 = 92900 nM
|
[28] | |||
| Compound Name |
2-(4-Cyanophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(4-Cyanoanilino)benzamide; CHEMBL2152578; SCHEMBL4646586; BDBM50392075
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[4] | |||
| Compound Name |
Methyl 3-[3-(2-carbamoylanilino)phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152570; BDBM50392066
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[4] | |||
| Compound Name |
Chembl4159477
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449711; L55
Click to Show/Hide
|
||||
| Activity |
IC50 = 93325.43 nM
|
[27] | |||
| Compound Name |
5-Butyl-8-(3-methylphenyl)-1,2,3,4-tetrahydropyrido[4,3-b]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408823; BDBM50070587
Click to Show/Hide
|
||||
| Activity |
IC50 = 96000 nM
|
[32] | |||
| Compound Name |
N-(1-(2-(1H-Indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-methoxyphenyl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397044; BDBM50241184; (E)-N-(1-(2-(1H-indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-methoxyphenyl)acrylamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 99000 nM
|
[8] | |||
| Compound Name |
Tert-butyl N-[2,2-dimethyl-4-[(3-nitrophenyl)carbamoylamino]-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084417; BDBM50267648
Click to Show/Hide
|
||||
| Activity |
IC50 = 99800 nM
|
[11] | |||
| Compound Name |
N-Methyl-2-(phenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-anilino-N-methylbenzamide; CHEMBL2152584; N-Methyl-2-anilinobenzamide; ARONIS26502; ZINC9379154; BDBM50392082; STL256966; AKOS005278800; CCG-286369; MCULE-3736029576; KS-00004844; Z30272269
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(4-Chloroanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152572; 2-[(4-chlorophenyl)amino]benzamide; Oprea1_738529; 2-(4-Chlorophenylamino)Benzamide; ZINC481300; BDBM50392068; MCULE-6884817479; AJ-333/13050075
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Nicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
niacinamide; 3-Pyridinecarboxamide; pyridine-3-carboxamide; Nicotinic acid amide; vitamin PP; Papulex; Aminicotin; Amixicotyn; Nicobion; Nicotylamide; Nikotinamid; Savacotyl; Benicot; Dipegyl; Endobion; Hansamid; Pelmine; Nicotinic amide; Delonin amide; Pelonin amide; Vi-Nicotyl; Austrovit PP; Inovitan PP; Vitamin B; Nicosylamide; Nicotilamide; Nicotililamido; Amnicotin; Niacevit; Nicamina; Nicamindon; Nicofort; Nicomidol; Nicotamide; Nicovitina; Nicovitol; Nicozymin; Niocinamide; Niozymin; Niamide; Nicasir; Nicogen; Nicota; Nicotol; Nicovit; Niko-tamin; 3-Carbamoylpyridine; Nicotine acid amide; Nandervit-N; Pyridine-3-carboxylic acid amide; Niavit PP; Nicosan 2; Nicotine amide; beta-Pyridinecarboxamide; Nikotinsaeureamid; Nicotylamidum; Mediatric; Nicotinsaureamid; Pyridine, 3-carbamoyl-; 3-Pyridinecarboxylic acid amide; Nicotinamidum; m-(Aminocarbonyl)pyridine; Acid amide; Factor pp; Nicotinamida; Nicovel; Vitamin B (VAN); Pelmin; Amid kyseliny nikotinove; Witamina PP; PP-Faktor; Amide PP; Nicotinsaureamid [German]; Nikotinsaeureamid [German]; Amid kyseliny nikotinove [Czech]; Nicotinamidum [INN-Latin]; Nicotinamida [INN-Spanish]; Nictoamide; CCRIS 1901; Dipigyl; HSDB 1237; Vi-noctyl; AI3-02906; Nicotinamide (Vitamin B3); NSC 13128; b-Pyridinecarboxamide; Niacinamide [USP]; UNII-25X51I8RD4; 3-(aminocarbonyl)pyridine; MFCD00006395; .beta.-Pyridinecarboxamide; CHEMBL1140; MLS000069714; 25X51I8RD4; NSC13128; Niacinamide (USP); NSC-13128; NSC-27452; Nicotinamide, 99%; NCGC00093354-03; NCGC00093354-05; SMR000058212; DSSTox_CID_929; Niacinamide;Nicotinic acid amide;Vitamin B3; WLN: T6NJ CVZ; DSSTox_RID_75873; DSSTox_GSID_20929; Niacinamide [USAN]; Enduramide; B3, Vitamin; Vitamin B 3; B 3, Vitamin; 3 Pyridinecarboxamide; SR-01000721872; Nicotinsaureamid Jenapharm; EINECS 202-713-4; Jenapharm, Nicotinsaureamid; Niacotinamide; Nicotinamid; nicotin-amide; Nicotinsaeureamid; 3-Amidopyridine; DEA No. 1405; Nicotinamide,(S); Vitamin B3 amide; 3-yridinecarboxamide; Nicotinamide [INN]; ACMC-20aizz; Mediatric (Salt/Mix); niacin - Vitamin B3; Opera_ID_775; Niacinamide(Vitamin B3); bmse000281; MolMap_000061; EC 202-713-4; SCHEMBL2926; Nicotinamide (JP17/INN); KSC237G2T; MLS001424246; SCHEMBL6278767; SGCUT00176; ZINC5878; DTXSID2020929; SCHEMBL19978192; BDBM27507; Nicotinamide, niacin, vitamin B3; HMS2052M21; HMS2090B05; HMS2093H03; HMS2236J03; HMS3370F21; HMS3394M21; HMS3655M20; HMS3713B22; HMS3884A16; Pharmakon1600-01505397; BCP07322; HY-B0150; Nicotinamide (Vitamin B3) solution; NSC27452; to_000073; Nicotinamide 1.0 mg/ml in Methanol; Nicotinamide, >=98.5% (HPLC); Nicotinamide, >=99.5% (HPLC); Tox21_111202; Tox21_201716; Tox21_302776; ANW-75549; BBL013003; NSC759115; s1899; SBB004283; STL163867; AKOS005715850; Tox21_111202_1; CCG-101149; CS-1968; DB02701; MCULE-3532732201; NC00399; NSC-759115; Nicotinamide, >=98% (HPLC), powder; NCGC00093354-04; NCGC00093354-06; NCGC00093354-09; NCGC00256432-01; NCGC00259265-01; AS-13845; Nicotinamide, puriss., 99.0-101.0%; SC-18039; Nicotinamide 10 microg/mL in Acetonitrile; Nicotinamide, tested according to Ph.Eur.; SBI-0206826.P001; DB-057754; FT-0631517; FT-0672696; FT-0773644; N0078; N1651; ST51037366; SW197779-3; EN300-15612; Niacinamide, meets USP testing specifications; 3418-EP2281816A1; 3418-EP2281818A1; 3418-EP2285778A1; 3418-EP2287165A2; 3418-EP2295424A1; 3418-EP2307377A1; 3418-EP2307378A1; 3418-EP2308858A1; 3418-EP2308874A1; 3418-EP2311808A1; 3418-EP2311829A1; C00153; D00036; J10422; Nicotinamide (Niacinamide), analytical standard; W-3583; 11783-EP2269610A2; 11783-EP2289510A1; 11783-EP2316457A1; 11783-EP2316458A1; 11783-EP2316825A1; 11783-EP2316826A1; 11783-EP2316827A1; 11783-EP2316828A1; AB00373895-13; AB00373895_15; AB00373895_16; Nicotinamide, Vetec(TM) reagent grade, >=98%; A845925; AC-907/25014114; Q192423; Q-201470; SR-01000721872-3; SR-01000721872-4; SR-01000721872-5; Z33546463; F2173-0513; A186B02E-6C70-4E54-9739-79398D439AAA
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[29] | |||
| Compound Name |
2-[3-[Methyl-(2-phenylacetyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152609; BDBM50392107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]pyridine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152601; BDBM50392099
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
1,6-Dimethyl-3-(4-methylphenyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1450796; SCHEMBL2181779; BDBM50438910; STK256714; CCG-144088; MCULE-2626397605; NCGC00168404-01; 1,6-dimethyl-3-(4-methylphenyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione; 1,6-Dimethyl-3-(p-tolyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
2-(4-Tert-butylanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152575; BDBM50392071
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-(2-Carbamoylphenylamino)Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152569; BDBM50392065; AKOS005925880
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(4-Isobutyramidophenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152596; BDBM50392094
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(Methyl(Phenyl)Amino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152587; 2-(N-methylanilino)benzamide; SCHEMBL2762268; BDBM50392085; AKOS034377912; MCULE-7499321790
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Chembl4159773
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449714
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[27] | |||
| Compound Name |
4-(2-Carbamoylphenylamino)Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152580; BDBM50392077; AKOS005925784
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(4-Phenylanilino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562473; SCHEMBL8420632; BDBM50392072
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-Phenoxybenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152586; phenoxybenzamide; SCHEMBL5724; Oprea1_299741; CTK9A2463; DTXSID50391112; ZINC2774449; BDBM50392084; STK127625; AKOS003282685; MCULE-1503641736; DA-03295; FT-0766665; ST50721718
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3,4-Bis(1-(7-hydroxyheptyl)-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL387119; BDBM50199957
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
N-(1-(2-(1H-Indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)cinnamamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472515; BDBM50244923
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[8] | |||
| Compound Name |
2-Anilino-N,N-dimethylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152585; ARONIS26399; BDBM50392083; STL256943; ZINC32814984; AKOS005278786; N,N-dimethyl-2-(phenylamino)benzamide; MCULE-9310392359; KS-00004819
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-[3-(2-Carbamoylanilino)phenyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152571; BDBM50392067
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(4-(Methylthio)Phenylamino)Benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152581; BDBM50392078
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(Benzylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152583; o-Benzylaminobenzamide; SCHEMBL2754257; BDBM50392081
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
5-(5-Butyl-1,2,3,4-tetrahydropyrido[4,3-b]indol-8-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408984; BDBM50070604
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[32] | |||
| Compound Name |
2-(4-Phenoxyphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562474; BDBM50392079; ZINC43120111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
N-[4-(2-Carbamoylanilino)phenyl]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152599; BDBM50392097
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-Phenylsulfanylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(phenylthio)benzamide; CHEMBL551610; (phenylthio)benzamide; Maybridge3_005605; SCHEMBL1030659; HMS1446O17; BDBM50297168; AKOS033210574; MCULE-3887291595; IDI1_016992
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-Butyl-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986181; BDBM50193045
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
2-[3-[Benzoyl(methyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152607; BDBM50392105
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-[3-(2-Hydroxylethyl)phenylamino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL572123; BDBM50297167
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N-methyl-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3771014; BDBM50148802
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
8-(3-Methylphenyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408825; BDBM50070585
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[32] | |||
| Compound Name |
N-Tert-butyl-6,11-dihydro-5H-benzo[b][1]benzazepine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3222152; BDBM50496764
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[31] | |||
| Compound Name |
2-[3-(Trifluoromethyl)anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152567; 2-{[3-(trifluoromethyl)phenyl]amino}benzamide; CBDivE_012401; SCHEMBL9270625; CTK0B9949; DTXSID50354904; HMS1578L07; ZINC283918; BDBM50392063; AKOS001063780; MCULE-4374720030; 2-(3-(Trifluoromethyl)Phenylamino)Benzamide; ST51067846; 2-[(3-trifluoromethylphenyl)amino]-benzamide; AE-848/32589053; Benzamide, 2-[[3-(trifluoromethyl)phenyl]amino]-; SR-01000196871; SR-01000196871-1; Z56935839
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[4] | |||
| Compound Name |
2-(3-Hydroxymethylphenylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561596; BDBM50297166; 2-(3-(Hydroxymethyl)Phenylamino)Benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-[3-[Methyl(phenyl)carbamoyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152603; BDBM50392101
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Methyl 3-(2-Carbamoylphenylamino)Benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152568; BDBM50392064
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3,4-Bis(1-heptyl-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL218785; BDBM50199955
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-(Naphthalen-2-ylamino)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152582; BDBM50392080
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-[3-(2-Carbamoylphenylamino)phenyl]acrylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551010; BDBM50297165
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
(E)-N-(1-(2-(1H-Indol-3-yl)ethylamino)-2-methyl-1-oxopropan-2-yl)-3-(4-fluorophenyl)acrylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL470972; BDBM50244925
Click to Show/Hide
|
||||
| Activity |
IC50 = 105000 nM
|
[8] | |||
| Compound Name |
(S)-N-(1-(2-(1H-Indol-3-yl)ethylamino)-1-oxopropan-2-yl)cinnamamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL472516; BDBM50244924
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[8] | |||
| Compound Name |
2-(3-(4-Tert-butylphenyl)-1,2,4-oxadiazole-5-carbonyl)-N-(4-(trifluoromethyl)phenyl)hydrazinecarbothioamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL466960; BDBM50261975; 3-[[3-(4-tertbutylphenyl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[4-trifluoromethylphenyl]thiourea
Click to Show/Hide
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||||
| Activity |
IC50 = 109000 nM
|
[20] | |||
| Compound Name |
Chembl4170414
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449702
Click to Show/Hide
|
||||
| Activity |
IC50 = 109500 nM
|
[27] | |||
| Compound Name |
Tert-butyl N-[4-[(4-cyanophenyl)carbamoylamino]-2,2-dimethyl-3,4-dihydrochromen-6-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092171; BDBM50267653
Click to Show/Hide
|
||||
| Activity |
IC50 = 110200 nM
|
[11] | |||
| Compound Name |
3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468178; BDBM50262014
Click to Show/Hide
|
||||
| Activity |
IC50 = 113000 nM
|
[20] | |||
| Compound Name |
2,4-Dioxo-N-(4-(pyridin-3-yloxy)phenyl)-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SIRT6-IN-1; CHEMBL3288034; 2,4-dioxo-N-[4-(pyridin-3-yloxy)phenyl]-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; SCHEMBL16179838; BDBM50017341; ZINC19339902; BRD-K25690991-001-01-3; F1902-0117; Z2037275165
Click to Show/Hide
|
||||
| Activity |
IC50 = 114000 nM
|
[33] | |||
| Compound Name |
Chembl4169706
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449720
Click to Show/Hide
|
||||
| Activity |
IC50 = 122600 nM
|
[27] | |||
| Compound Name |
[[(2R,3S,4R,5R)-5-(6-Amino-8-phenylpurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3350585
Click to Show/Hide
|
||||
| Activity |
IC50 = 123000 nM
|
[12] | |||
| Compound Name |
N-[5-(Naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]-2-[(6-oxo-4-propyl-1H-pyrimidin-2-yl)sulfanyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3769476; BDBM50148801
Click to Show/Hide
|
||||
| Activity |
IC50 = 127200 nM
|
[25] | |||
| Compound Name |
Chembl4166294
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449699
Click to Show/Hide
|
||||
| Activity |
IC50 = 127700 nM
|
[27] | |||
| Compound Name |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-(cyclohex-1-enecarboxamido)hexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254614; BDBM50326788
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[24] | |||
| Compound Name |
3-[[3-(Tert-Butoxycarbonylamino-phenyl)-1,2,4-oxadiazole-5-carbonyl]amino]-1-(4-(trifluoromethyl)phenyl)thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL469018; BDBM50261821
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[20] | |||
| Compound Name |
(Z)-6,7-Dichloro-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]indolin-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569684; BDBM50303773; NSC745322; NSC-745322
Click to Show/Hide
|
||||
| Activity |
IC50 = 135400 nM
|
[3] | |||
| Compound Name |
3-[N-(2-Cyanoethyl)-4-[[4-[4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)-1,3-thiazol-2-yl]piperidin-1-yl]methyl]anilino]propanenitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215427; SCHEMBL3886177; BDBM50199446; AB00045801-01
Click to Show/Hide
|
||||
| Activity |
IC50 = 136000 nM
|
[35] | |||
| Compound Name |
N,N''-Bis(4-hydroxybenzylidene)naphthalene1,4diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220354; BDBM50201114
Click to Show/Hide
|
||||
| Activity |
IC50 = 137400 nM
|
[19] | |||
| Compound Name |
Chembl4172158
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449732
Click to Show/Hide
|
||||
| Activity |
IC50 = 141253.75 nM
|
[27] | |||
| Compound Name |
Chembl4163559
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449727
Click to Show/Hide
|
||||
| Activity |
IC50 = 141253.75 nM
|
[27] | |||
| Compound Name |
2-(3-Hydroxyphenyl)sulfanyl-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770074; BDBM50148768
Click to Show/Hide
|
||||
| Activity |
IC50 = 143000 nM
|
[25] | |||
| Compound Name |
(1R,3R,5R)-7-Benzoyl-6-methoxy-4,4-dimethyl-1,5-bis(3-methylbut-2-enyl)-8,9-dioxobicyclo[3.3.1]non-6-ene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3894424; BDBM50195222
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[37] | |||
| Compound Name |
Lys-Lys(epsilon-thioAc)-Leu
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492309; BDBM50257287
Click to Show/Hide
|
||||
| Activity |
IC50 = 151000 nM
|
[16] | |||
| Compound Name |
N-[4-(Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1H-quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3622695; SCHEMBL16179458; BDBM50123357; ZINC19334956; AKOS026699891; F9994-0201; N-(4-((1H-imidazol-1-yl)methyl)phenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; N-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 159000 nM
|
[33] | |||
| Compound Name |
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N-[5-[(4-phenylphenyl)methyl]-1,3-thiazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3771179; BDBM50148826
Click to Show/Hide
|
||||
| Activity |
IC50 = 164500 nM
|
[25] | |||
| Compound Name |
N-[5-[(4-Bromophenyl)methyl]-1,3,4-thiadiazol-2-yl]-2-(4,6-dimethylpyrimidin-2-yl)sulfanylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770257; BDBM50148756
Click to Show/Hide
|
||||
| Activity |
IC50 = 167700 nM
|
[25] | |||
| Compound Name |
Chembl4161387
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449725
Click to Show/Hide
|
||||
| Activity |
IC50 = 168800 nM
|
[27] | |||
| Compound Name |
Cinnamoyl tryptamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
trans-N-[2-(3-Indolyl)ethyl]cinnamamide; UNII-XY7RW8O14Q; XY7RW8O14Q; CHEMBL520706; (E)-N-[2-(1H-indol-3-yl)ethyl]-3-phenylprop-2-enamide; (2E)-N-(2-indol-3-ylethyl)-3-phenylprop-2-enamide; Melaeser; MFCD00170475; N-(2-indol-3-ylethyl)-3-phenylprop-2-enamide; Cinnamoyl tryptamine [INCI]; n-(trans-cinnamoyl)tryptamine; MLS001143325; HMS2778F06; ZINC341045; BDBM50245092; SBB062542; STK530883; AKOS005463454; NCGC00311159-01; AC-29782; BAS 00337757; N-(2-(1H-indol-3-yl)ethyl)cinnamamide; SMR000473160; ST50950588; AB00894236-05; Q27294056; (2E)-N-[2-(1H-indol-3-yl)ethyl]-3-phenylacrylamide; (2E)-N-[2-(1H-indol-3-yl)ethyl]-3-phenylprop-2-enamide; 2-Propenamide, N-(2-(1H-indol-3-yl)ethyl)-3-phenyl-, (2E)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 173000 nM
|
[8] | |||
| Compound Name |
Chembl4173306
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449708
Click to Show/Hide
|
||||
| Activity |
IC50 = 173780.08 nM
|
[27] | |||
| Compound Name |
Asp-Lys(epsilon-thioAc)-Thr
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493355; BDBM50257238
Click to Show/Hide
|
||||
| Activity |
IC50 = 175000 nM
|
[28] | |||
| Compound Name |
2-Benzoyl-1H-benzo[f]chromen-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797737; 2-benzoyl-1H,2H,3H-naphtho[2,1-b]pyran-3-one; SCHEMBL1710776; BDBM50346539; AKOS002367589; AKOS016327811; MCULE-3084067707; 2-(phenylcarbonyl)benzo[f]chroman-3-one; 2-benzoyl-1,2-dihydrobenzo[f]chromen-3-one; ST50405051; 1,2-Dihydro-2-benzoyl-3H-naphtho[2,1-b]pyran-3-one; F3308-2800
Click to Show/Hide
|
||||
| Activity |
IC50 = 178700 nM
|
[10] | |||
| Compound Name |
(S)-Methyl 2-((S)-6-acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254125; BDBM50326790
Click to Show/Hide
|
||||
| Activity |
IC50 = 180000 nM
|
[24] | |||
| Compound Name |
(2S)-N-[(2S)-6-Acetamido-1-amino-1-oxohexan-2-yl]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]octanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814816; BDBM50350511
Click to Show/Hide
|
||||
| Activity |
IC50 = 190200 nM
|
[38] | |||
| Compound Name |
10-Phenyl-7-oxa-8,10-diaza-benzo[a]anthracene-9,11-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL596657; SCHEMBL18134586; BDBM50309831
Click to Show/Hide
|
||||
| Activity |
IC50 = 191200 nM
|
[23] | |||
| Compound Name |
N,N''-Bis(3-hydroxybenzylidene)naphthalene1,4diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220300; BDBM50201113
Click to Show/Hide
|
||||
| Activity |
IC50 = 195900 nM
|
[19] | |||
| Compound Name |
N-[3-(2-Ethylhexoxy)propyl]-4,4-bis(4-hydroxyphenyl)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215284; SCHEMBL3892123; BDBM50199447; AB00013418-01; N-(3-(2-ethylhexyloxy)propyl)-4,4-bis(4-hydroxyphenyl)pentanamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 200000 nM
|
[35] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 57 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Resveratrol
Click to Show/Hide
|
Phase 3 | Compound Info | ||
| Synonyms |
Resveratrol; Resvida; KUC104385N; R 5010; SRT 501; Cis-resveratrol; PREVENTION 8 (RESVERATROL); RM-1812; SRT-501; Trans-resveratrol; CU-01000001503-3; KSC-10-164; Resveratrol-3-sulfate; Trans-3,4',5-trihydroxystilbene; Trans-3,4′,5-Trihydroxystilbene; Trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene; (E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol
Click to Show/Hide
|
||||
| Activity |
EC50 > 300000 nM
|
[39] | |||
| Compound Name |
2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL611665; 2H-chromeno[2,3-d]pyrimidine-2,4(3H)-dione; chromeno[2,3-d]pyrimidine-2,4-dione; AC1LQMEG; 5-Deaza-10-oxaflavin; SCHEMBL11333239; BFMCRAXOACCPEL-UHFFFAOYSA-; ZINC1280587; STK236511; BDBM50309832; AKOS000428551; MCULE-3496773034; ST50987740; 3-hydrochromeno[2,3-d]pyrimidine-2,4-dione; 2H,3H,4H-chromeno[2,3-d]pyrimidine-2,4-dione; 2H-[1]Benzopyrano[2,3-d]pyrimidine-2,4(3H)-dione; InChI=1/C11H6N2O3/c14-9-7-5-6-3-1-2-4-8(6)16-10(7)13-11(15)12-9/h1-5H,(H,12,14,15)
Click to Show/Hide
|
||||
| Activity |
IC50 = 243600 nM
|
[5] | |||
| Compound Name |
1-(6-Chloro-2,2-dimethyl-3,4-dihydrochromen-4-yl)-3-(4-nitrophenyl)thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL608379; BDBM50267661
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[11] | |||
| Compound Name |
(2S)-6-Acetamido-2-[[(2S)-6-[6-(1,3-benzothiazol-2-ylsulfanyl)hexanoylamino]-2-[[(2S)-2,6-diacetamidohexanoyl]amino]hexanoyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883974; BDBM50209638
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[40] | |||
| Compound Name |
4-[(2-Hydroxy-3-methoxynaphthalen-1-yl)methyl]-5-(4-methylphenyl)-1,2-dihydropyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233742; BDBM50004777
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
4-[(6-Bromo-2-hydroxynaphthalen-1-yl)methyl]-5-(4-methylphenyl)-1,2-dihydropyrazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3233739; BDBM50004765
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
2-(3,5-Dimethylphenyl)sulfanyl-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3769737; BDBM50148772
Click to Show/Hide
|
||||
| Activity |
IC50 = 207000 nM
|
[25] | |||
| Compound Name |
(S)-2-((S)-6-Acetamido-2-((S)-2-acetamidopropanamido)hexanamido)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254124; BDBM50326789
Click to Show/Hide
|
||||
| Activity |
IC50 = 223000 nM
|
[24] | |||
| Compound Name |
Chembl4129734
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276142
Click to Show/Hide
|
||||
| Activity |
IC50 = 237000 nM
|
[41] | |||
| Compound Name |
Ser-Asp-Lys(epsilon-thioAc)Leu-Ile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL503595; BDBM50257290
Click to Show/Hide
|
||||
| Activity |
IC50 = 238000 nM
|
[28] | |||
| Compound Name |
1,3-Dimethyl-2,4-dioxo-N-[4-(pyridin-4-ylmethyl)phenyl]quinazoline-6-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623254; 1,3-dimethyl-2,4-dioxo-N-[4-(pyridin-4-ylmethyl)phenyl]-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; ZINC1069449; BDBM50123399; STK665401; AKOS003404699; MCULE-8902652642; ST056684; 1,3-dimethyl-6-({[4-(4-pyridylmethyl)phenyl]amino}sulfonyl)-1,3-dihydroquinazo line-2,4-dione
Click to Show/Hide
|
||||
| Activity |
IC50 = 242000 nM
|
[33] | |||
| Compound Name |
5-(2-Methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-8-yl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408983; BDBM50070603
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[32] | |||
| Compound Name |
2-Methyl-8-(4-methylsulfonylphenyl)-1,3,4,5-tetrahydropyrido[4,3-b]indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3408818; BDBM50070601
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[32] | |||
| Compound Name |
3-[[3-(Naphthalen-1-yl)1,2,4-oxadiazole-5-carbonyl]amino]-1-[3-trifluoromethylphenyl]urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL468596; BDBM50261756
Click to Show/Hide
|
||||
| Activity |
IC50 = 257000 nM
|
[20] | |||
| Compound Name |
Chembl4164275
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449721
Click to Show/Hide
|
||||
| Activity |
IC50 = 269153.48 nM
|
[27] | |||
| Compound Name |
1-[2-[[5-(Naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]amino]-2-oxoethyl]pyridin-1-ium-3-carboxamide;chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3771167; BDBM50148773
Click to Show/Hide
|
||||
| Activity |
IC50 = 289000 nM
|
[25] | |||
| Compound Name |
4-(2-(4-(4-Chlorophenyl)-5-mercapto-4H-1,2,4-triazol-3-yl)ethyl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426391; Maybridge1_000434; Oprea1_682082; HMS542L16; ZINC67499; BDBM50156771; MCULE-1656453518
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[42] | |||
| Compound Name |
Chembl4166056
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449719
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4168392
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449697
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4167724
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449722
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4162080
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449729
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
3,4,5-Trimethoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SRT1460; SRT-1460; SRT 1460; CHEMBL254156; SCHEMBL1302286; CTK8B7551; DTXSID40636044; ANW-57653; BDBM50228364; MFCD19053214; s6880; ZINC29043683; AKOS016001432; DB-079334; HY-124037; CS-0084007; FT-0751517; J-511115; BRD-K20979596-019-01-6
Click to Show/Hide
|
||||
| Activity |
EC50 > 300000 nM
|
[39] | |||
| Compound Name |
Chembl4176250
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449730
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[27] | |||
| Compound Name |
3-(3-(4-(Phenoxymethyl)phenyl)ureido)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL224844; Oprea1_001621; MLS001181780; HMS2879J16; ZINC1032704; BDBM50156767; CCG-41833; MCULE-7066377765; SMR000567497; SR-01000631881-1
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[42] | |||
| Compound Name |
4-((4-(2,3-Dihydro-1H-inden-2-yl)-5-hydroxy-4H-1,2,4-triazol-3-ylthio)methyl)-7-hydroxy-2H-chromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL387393; HTS-08006; Oprea1_243504; ZINC4333888; BDBM50156769; CCG-239229; MCULE-1931944855
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[42] | |||
| Compound Name |
Chembl4164971
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449731
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4163136
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449713
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4165789
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449736
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
(R)-N-(2-(3-((3-Hydroxypyrrolidin-1-yl)methyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-naphthamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SRT2183; SRT-2183; CHEMBL403308; SCHEMBL1325303; HMS3886H08; EX-A4217; BDBM50376978; s8270; ZINC29043608; CCG-269435; AC-33072; HY-19759; CS-0016574; Q7392861
Click to Show/Hide
|
||||
| Activity |
EC50 > 300000 nM
|
[39] | |||
| Compound Name |
Chembl4171097
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449735
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4162839
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449700
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
2-[4-[(E)-2-Phenylethenyl]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152589; BDBM50392087
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[4] | |||
| Compound Name |
Chembl4160877
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449703
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4173850
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449705
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4172874
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449698
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[27] | |||
| Compound Name |
Chembl4173707
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449723
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
Chembl4160492
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449734
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[27] | |||
| Compound Name |
2-[4-[Benzoyl(methyl)amino]anilino]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2152593; BDBM50392091
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[4] | |||
| Compound Name |
2-[[4-(1,3-Dioxoisoindol-2-yl)benzoyl]amino]-5-hydroxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4217987; Oprea1_591707; SCHEMBL4728715; ZINC4823829; BDBM50451276; STK223532; AKOS003264826; MCULE-2189201025; SR-01000250375; SR-01000250375-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 333000 nM
|
[43] | |||
| Compound Name |
(S)-Methyl 2-((S)-2-((S)-2-acetamidopropanamido)-6-pivalamidohexanamido)propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1254218; BDBM50326791
Click to Show/Hide
|
||||
| Activity |
IC50 = 338000 nM
|
[24] | |||
| Compound Name |
Sirt6-IN-5
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4206619; 5-(4-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid; SCHEMBL16179518; BDBM50451274; STK276510; AKOS005425617; MCULE-7588193558; 5-[4-(FURAN-2-AMIDO)BENZAMIDO]-2-HYDROXYBENZOIC ACID; 5-[[4-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid; 5-[({4-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
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| Activity |
IC50 = 453000 nM
|
[43] | |||
| Compound Name |
4-[[4-(Furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4205716; SCHEMBL16179844; ZINC4945036; BDBM50451275; STK292624; AKOS000644917; MCULE-8086974834; 4-[4-(FURAN-2-AMIDO)BENZAMIDO]-2-HYDROXYBENZOIC ACID; 4-[({4-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
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| Activity |
IC50 = 482000 nM
|
[43] | |||
| Compound Name |
2-(4,6-Dimethylpyrimidin-2-yl)sulfanyl-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3770610; BDBM50148766; EU-0005213
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| Activity |
IC50 = 502800 nM
|
[25] | |||
| Compound Name |
5-(3-(Furan-2-carboxamido)benzamido)-2-hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
OSS_128167; OSS-128167; CHEMBL1588664; MLS001208603; SCHEMBL16179714; HMS2819N24; BCP28960; EX-A3569; ZINC4945038; 5-[[3-(furan-2-carbonylamino)benzoyl]amino]-2-hydroxybenzoic acid; 5-{3-[(Furan-2-carbonyl)-amino]-benzoylamino}-2-hydroxy-benzoic acid; BDBM50017342; OSS128167; s8627; STK292625; AKOS000644951; CCG-268237; OSS-128167(SIRT6-IN-1); BS-17805; SMR000525099; HY-107454; CS-0028514; 5-[3-(furan-2-amido)benzamido]-2-hydroxybenzoic acid; F1905-7264; OSS 128167; OSS-128167; SIRT6-IN-1; 5-[({3-[(furan-2-ylcarbonyl)amino]phenyl}carbonyl)amino]-2-hydroxybenzoic acid
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| Activity |
IC50 = 751000 nM
|
[43] | |||
| Compound Name |
Methyl (2S)-2-[[(2S)-2-acetamido-6-(ethanethioylamino)hexanoyl]amino]propanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835300; BDBM50355042
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| Activity |
IC50 = 862000 nM
|
[16] | |||
| Compound Name |
2-((4-(3-(4-(2-Hydroxybenzylideneamino)phenoxy)propoxy)phenylimino)methyl)phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222495; CCG-756; ZINC3126675; BDBM50156765; MCULE-2789559832
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
4,4'-Bis[(2-hydroxyethyl)methylamino]benzophenone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225118; 4,4'-Bis((2-hydroxyethyl)methylamino)benzophenone; bis(4-((2-hydroxyethyl)(methyl)amino)phenyl)methanone; Bis{4-[(2-hydroxyethyl)(methyl)amino]phenyl}methanone; bis[4-[2-hydroxyethyl(methyl)amino]phenyl]methanone; EINECS 274-124-0; Maybridge3_003489; Oprea1_733816; SCHEMBL8975652; CTK5D1376; DTXSID60990074; HMS1440O13; ZINC163092; BDBM50156758; CCG-253680; MCULE-3897853810; IDI1_014876; Bis[4-[(2-hydroxyethyl)methylamino]phenyl]methanone; Methanone,bis[4-[(2-hydroxyethyl)methylamino]phenyl]-
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
4-((4-(4-(3,4-Dihydroxybenzylideneamino)benzyl)phenylimino)methyl)benzene-1,2-diol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL374739; ARONIS017393; KS-000049TO; ZINC1045505; BDBM50156766; STK053637; AKOS000484538; MCULE-1575897159; 4,4'-[methylenebis(4,1-phenylenenitrilomethylylidene)]di(1,2-benzenediol)
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
2-(2-Oxo-2-(4-(2-(trifluoromethyl)quinolin-4-yl)piperazin-1-yl)ethylthio)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL385802; Maybridge3_001991; MLS001181726; HMS1436K11; HMS2876B06; ZINC4324522; BDBM50156773; MCULE-6511769349; IDI1_013378; SMR000567433
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
5-(4-Benzamido-2-methoxy-5-methylphenylamino)-5-oxo-3-phenylpentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225082; Oprea1_702068; MLS001181785; HMS2864C15; BDBM50156772; CCG-48063; MCULE-9477695971; SMR000567538; SR-01000637634-1
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
5-(9-Oxoxanthen-2-yl)oxypentanoic Acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222502; SCHEMBL9424067; ZINC4344168; BDBM50156764; 5-(9-Oxoxanthen-2-oxy)valeric Acid; 5-(9-oxoxanthen-2-oxy) valeric acid; CCG-251358; MCULE-9075724348; 5-(9-oxo-9H-xanthen-2-yloxy)pentanoic acid
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| Activity |
IC50 > 1000000 nM
|
[42] | |||
| Compound Name |
4-(3-(2-Hydroxybenzamido)phenylamino)-4-oxobut-2-enoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222448; CCG-573; BDBM50156770; ZINC12368020
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| Activity |
IC50 > 1000000 nM
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[42] | |||
| Compound Name |
2-((4-(4-(4-(2-Hydroxybenzylideneamino)phenoxy)butoxy)phenylimino)methyl)phenol
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL222147; CCG-757; BDBM50156768; 2,2'-Tetramethylenebis(oxy-1,4-phenylenenitrilomethylidyne)bisphenol
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| Activity |
IC50 > 1000000 nM
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[42] | |||
| Compound Name |
6-(2-Hydroxy-ethylsulfanyl)-2-(2-pyridin-2-yl-ethyl)-benzo[de]isoquinoline-1,3-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL441874; CDS1_000834; Maybridge1_005586; DivK1c_001874; HMS557F20; ZINC4347906; BDBM50156761; CCG-48982; PHG 01042; MCULE-7197202095; SR-01000638475-1
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| Activity |
IC50 > 1000000 nM
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[42] | |||
| Compound Name |
2-(4-((2-(Tert-butoxycarbonyl)-3-phenylpropanoyloxy)methyl)phenyl)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL225007; BDBM50156762; STL574569; [4-({[N-(tert-butoxycarbonyl)phenylalanyl]oxy}methyl)phenyl]acetic acid
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| Activity |
IC50 > 1000000 nM
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[42] | |||
| Compound Name |
4-(3-{[Amino(phenylimino)methyl]sulfanyl}-2,5-dioxo-1-pyrrolidinyl)benzoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3288044; BDBM50017344; STK372656; AKOS000583963; AKOS022014134; MCULE-1337998480; ST007178; 4-[3-((1E)-1-amino-2-phenyl-2-azavinylthio)-2,5-dioxoazolidinyl]benzoic acid; 4-{2,5-dioxo-3-[(N'-phenylcarbamimidoyl)sulfanyl]pyrrolidin-1-yl}benzoic acid
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| Activity |
IC50 = 1744000 nM
|
[44] | |||
| Compound Name |
N-[(3-Pyridin-3-yl-1H-1,2,4-triazol-5-yl)methyl]pyrazine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3288043; SCHEMBL16511175; BDBM50017343; SR-01000335214; SR-01000335214-1
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| Activity |
IC50 = 2291000000 nM
|
[44] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors. J Med Chem. 2014 Apr 24;57(8):3283-94. | ||||
| REF 2 | Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. J Med Chem. 2006 Dec 14;49(25):7307-16. | ||||
| REF 3 | Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins). J Med Chem. 2010 Feb 11;53(3):1383-6. | ||||
| REF 4 | Design, synthesis, and biological activity of a novel series of human sirtuin-2-selective inhibitors. J Med Chem. 2012 Jun 28;55(12):5760-73. | ||||
| REF 5 | Characterization of sirtuin inhibitors in nematodes expressing a muscular dystrophy protein reveals muscle cell and behavioral protection by specif... J Med Chem. 2010 Feb 11;53(3):1407-11. | ||||
| REF 6 | Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79. | ||||
| REF 7 | Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27;317(5837):516-9. | ||||
| REF 8 | Characterization of the binding properties of SIRT2 inhibitors with a N-(3-phenylpropenoyl)-glycine tryptamide backbone. Bioorg Med Chem. 2008 Sep 1;16(17):8054-62. | ||||
| REF 9 | Synthesis and biological characterisation of sirtuin inhibitors based on the tenovins. Bioorg Med Chem. 2012 Mar 1;20(5):1779-93. | ||||
| REF 10 | Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile. Bioorg Med Chem. 2011 Jun 15;19(12):3659-68. | ||||
| REF 11 | Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines. J Med Chem. 2017 Jun 8;60(11):4714-4733. | ||||
| REF 12 | Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD). J Med Chem. 2011 May 26;54(10):3492-9. | ||||
| REF 13 | US patent application no. 9365508B2, Aroyl thiourea derivatives | ||||
| REF 14 | Benzimidazoles as new scaffold of sirtuin inhibitors: green synthesis, in vitro studies, molecular docking analysis and evaluation of their anti-cancer properties. Eur J Med Chem. 2014 Aug 18;83:448-54. | ||||
| REF 15 | Discovery of a potent and highly fluorescent sirtuin inhibitor. Medchemcomm. 2015;6:1857-63. | ||||
| REF 16 | Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2. J Med Chem. 2011 Oct 13;54(19):6456-68. | ||||
| REF 17 | Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode. J Med Chem. 2008 Mar 13;51(5):1203-13. | ||||
| REF 18 | Synthesis and evaluation of novel benzimidazole derivatives as sirtuin inhibitors with antitumor activities. Bioorg Med Chem. 2014 Jan 15;22(2):703-10. | ||||
| REF 19 | N,N'-Bisbenzylidenebenzene-1,4-diamines and N,N'-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors. J Med Chem. 2006 Dec 28;49(26):7907-11. | ||||
| REF 20 | Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors. J Med Chem. 2008 Aug 14;51(15):4377-80. | ||||
| REF 21 | Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton. Bioorg Med Chem. 2015 Jan 15;23(2):328-39. | ||||
| REF 22 | Novel thiourea-based sirtuin inhibitory warheads. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3319-24. | ||||
| REF 23 | Benzodeazaoxaflavins as sirtuin inhibitors with antiproliferative properties in cancer stem cells. J Med Chem. 2012 Sep 27;55(18):8193-7. | ||||
| REF 24 | N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2. Bioorg Med Chem. 2010 Aug 1;18(15):5616-25. | ||||
| REF 25 | Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study. J Med Chem. 2016 Feb 25;59(4):1599-612. | ||||
| REF 26 | SIRT1 modulation as a novel approach to the treatment of diseases of aging. J Med Chem. 2011 Jan 27;54(2):417-32. | ||||
| REF 27 | X-ray crystal structure guided discovery of new selective, substrate-mimicking sirtuin 2 inhibitors that exhibit activities against non-small cell lung cancer cells. Eur J Med Chem. 2018 Jul 15;155:806-823. | ||||
| REF 28 | N(epsilon)-thioacetyl-lysine-containing tri-, tetra-, and pentapeptides as SIRT1 and SIRT2 inhibitors. J Med Chem. 2009 Apr 9;52(7):2153-6. | ||||
| REF 29 | Development of second generation epigenetic agents. Medchemcomm. 2012;3:135-61. | ||||
| REF 30 | Computer- and structure-based lead design for epigenetic targets. Bioorg Med Chem. 2011 Jun 15;19(12):3605-15. | ||||
| REF 31 | The Discovery of Novel 10,11-Dihydro-5H-dibenz[b,f]azepine SIRT2 Inhibitors. Medchemcomm. 2012 Mar 1;(3):10.1039/C2MD00290F. | ||||
| REF 32 | Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity. Eur J Med Chem. 2015 Mar 6;92:145-55. | ||||
| REF 33 | Quinazolinedione SIRT6 inhibitors sensitize cancer cells to chemotherapeutics. Eur J Med Chem. 2015 Sep 18;102:530-9. | ||||
| REF 34 | Novel cambinol analogs as sirtuin inhibitors: synthesis, biological evaluation, and rationalization of activity. J Med Chem. 2009 May 14;52(9):2673-82. | ||||
| REF 35 | Discovering inhibitors of human sirtuin type 2: novel structural scaffolds. J Med Chem. 2006 Nov 30;49(24):7239-41. | ||||
| REF 36 | How much successful are the medicinal chemists in modulation of SIRT1: A critical review. Eur J Med Chem. 2016 Aug 25;119:45-69. | ||||
| REF 37 | Guttiferone A Aggregates Modulate Silent Information Regulator 1 (SIRT1) Activity. J Med Chem. 2016 Oct 27;59(20):9560-9566. | ||||
| REF 38 | Potent sirtuin inhibition bestowed by l-2-amino-7-carboxamidoheptanoic acid (l-ACAH), a Nepsilon-acetyl-lysine analog. Medchemcomm. 2011;2:291-9. | ||||
| REF 39 | Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007 Nov 29;450(7170):712-6. | ||||
| REF 40 | Bivalent SIRT1 inhibitors. Bioorg Med Chem Lett. 2017 Jan 15;27(2):180-186. | ||||
| REF 41 | The mimics of N -acyl-lysine derived from cysteine as sirtuin inhibitors. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2375-2378. | ||||
| REF 42 | An in silico approach to discovering novel inhibitors of human sirtuin type 2. J Med Chem. 2004 Dec 2;47(25):6292-8. | ||||
| REF 43 | SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects. Bioorg Med Chem. 2017 Oct 15;25(20):5849-5858. | ||||
| REF 44 | Discovery of novel and selective SIRT6 inhibitors. J Med Chem. 2014 Jun 12;57(11):4796-804. | ||||
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