Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T86264 | Target Info | |||
| Target Name | Solute carrier family 40 member 1 (SLC40A1) | ||||
| Synonyms |
SLC11A3; MSTP079; IREG1; Ferroportin-1; FPN1
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| Target Type | Clinical trial Target | ||||
| Gene Name | SLC40A1 | ||||
| Biochemical Class | Ferroportin protein | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 40 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Methyl 8-(benzenesulfonamido)quinoline-4-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3953777; SCHEMBL11973299; 8-Benzenesulfonylamino-quinoline-4-carboxylic acid methyl ester
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| Activity |
IC50 = 50000 nM
|
[1] | |||
| Compound Name |
Methyl 2-(quinolin-8-ylsulfamoyl)benzoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3942863; SCHEMBL11973518; 2-(Quinolin-8-ylsulfamoyl)-benzoic acid methyl ester
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| Activity |
IC50 = 58100 nM
|
[1] | |||
| Compound Name |
N-(5,7-Dichloroquinolin-8-yl)-4-methylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_219868; CBDivE_011388; CHEMBL3936153; SCHEMBL11973810; ZINC758709; MCULE-2832770991; SR-01000391345; SR-01000391345-1
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| Activity |
IC50 = 79000 nM
|
[1] | |||
| Compound Name |
N-(2-Chloroquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3928897; SCHEMBL11973639; N-(2-Chloroquinolin-8-yl)-benzenesulfonamide; Benzenesulfonamide,N-(2-chloro-8-quinolinyl)-
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Amino-4-methyl-N-(3-methylquinolin-8-yl)-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3975758; SCHEMBL11972840; 2-amino-4-methyl-N-(3-methylquinolin-8-yl)benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(2-Methylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
MLS001125540; SMR000658872; CBMicro_006566; Oprea1_721946; SCHEMBL6984645; CHEMBL1321754; BDBM58565; cid_2848041; KUC112867N; ZINC194580; SMSF0005877; CCG-15593; AKOS001607863; CB08866; MCULE-8027209540; KSC-325-058; BIM-0006538.P001; N-(2-methyl-8-quinolyl)benzenesulfonamide; N-(2-methyl-8-quinolinyl)benzenesulfonamide; N-(2-Methylquinolin-8-yl)-benzenesulfonamide; MLS-0373733.0001; BRD-K36043479-001-07-0
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2,4-Dichloro-N-(5-chloroquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3904197; SCHEMBL11973856; 2,4-Dichloro-N-(5-chloro-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Amino-N-(5-chloroquinolin-8-yl)-4-(trifluoromethyl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3898092; SCHEMBL11972920; 2-Amino-N-(5-chloro-quinolin-8-yl)-4-trifluoromethyl-benzenesulfonamide; 2-Amino-N-(5-chloroquinolin-8-yl)-4-trifluoromethyl-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Amino-4-methoxy-N-(2-methylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3934171; SCHEMBL11973339; NCGC00163069-01; CU-00000000258-1; 2-Amino-4-methoxy-N-(2-methyl-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(7-Ethylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926407; SCHEMBL11973659; N-(7-Ethyl-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
11-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3956703; SCHEMBL11973889; 11-methoxy-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(5-Chloro-6-methylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3892051; SCHEMBL11973396; N-(5-Chloro-6-methyl-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
1-Methoxy-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3893426; SCHEMBL11973651; 1-methoxy-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(5,6-Dimethylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986484; SCHEMBL11973058; N-(5,6-Dimethyl-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(4-Methoxyquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3927455; SCHEMBL11973450; N-(4-Methoxy-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
5-Methyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3910392; SCHEMBL11973461; 5-methylquinolino[8,7-c][1,2]benzothiazine 6,6-dioxide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(2,6-Difluorophenyl)[(6-methoxyquinolin-8-yl)amino]sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3933528; SCHEMBL11973497; N-[(2,6-difluorophenyl)sulfamoyl]-6-methoxyquinolin-8-amine
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2,4-Dichloro-N-(3-methylquinolin-8-yl)benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3896934; SCHEMBL11972900
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(6-Chloroquinolin-8-yl)benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3952348; SCHEMBL11973412; AKOS009160445; N-(6-Chloro-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2,4-Dichloro-N-(6-methoxyquinolin-8-yl)benzenesulfonamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3965637; SCHEMBL11973509
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(7-Methylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3907573; SCHEMBL11972869; N-(7-Methylquinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-[2-(Quinolin-8-ylsulfamoyl)-5-(trifluoromethyl)phenyl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3953438; SCHEMBL11973726; N-[2-(Quinolin-8-ylsulfamoyl)-5-trifluoromethyl-phenyl]-acetamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
OC1=CC=C2C=CC=NC2=C1NS(=O)(=O)C1=CC=CC=C1
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3986202; SCHEMBL11973640
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|
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(5,7-Dichloroquinolin-8-yl)-2,4,6-trimethylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_070718; CBDivE_011224; CHEMBL3986143; SCHEMBL11973233; ZINC1233335; MCULE-5358824358; SR-01000391347; SR-01000391347-1
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Methyl-N-(8-quinolinyl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3964091; SCHEMBL11973197; ZINC68677052; AKOS012298584; MCULE-9189992046; 2-methyl-N-quinolin-8-ylbenzenesulfonamide; 2-Methyl-N-quinolin-8-yl-benzenesulfonamide; AA-504/36995228
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Amino-4-methoxy-N-quinolin-8-ylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3392504; SCHEMBL11973032; NCGC00161708-01; CU-00000000251-1; 2-Amino-4-methoxy-N-quinolin-8-yl-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
3-Methyl-5H-6-thia-4,5-diaza-chrysene 6,6-dioxide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1729471; CHEMBL3913079; SCHEMBL11972877; NCGC00161711-01; CU-00000000255-1; 2-(2-Methyl-8-amino*-7-quinolinyl)benzenesulfonic acid sultam; 3-methyl-5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(5-Bromoquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3894606; SCHEMBL11973665; CCG-15217; N-(5-Bromo-quinolin-8-yl)-benzenesulfonamide; SR-01000391337; SR-01000391337-1
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Methoxy-N-quinolin-8-ylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3956684; SCHEMBL11972879; BDBM50517440; ZINC52536998; AKOS027676810; MCULE-8069151562; 2-Methoxy-N-quinolin-8-yl-benzenesulfonamide; 2-methoxy-N-(quinolin-8-yl)benzene-1-sulfonamide; Z115639252
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
4-Methoxy-N-quinolin-8-ylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3392552; SCHEMBL7193613; ZINC5140721; BDBM50277834; AKOS001394432; MCULE-9344006764; NCGC00161716-01; 4-methoxy-N-(8-quinolyl)benzenesulfonamide; N-(8-Quinolyl)-4-methoxybenzenesulfonamide; 4-Methoxy-N-quinolin-8-yl-benzenesulfonamide; J3.663.035C; CU-00000000140-1
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
5-Chloro-N-[(3-chloro-2-methylphenyl)sulfamoyl]quinolin-8-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3965422; SCHEMBL11973417; N-(3-Chloro-2-methylphenyl)[(5-chloroquinolin-8-yl)amino]sulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(6-Ethoxyquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926321; SCHEMBL11973772; N-(6-Ethoxy-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Nitro-N-quinolin-8-yl-4-(trifluoromethyl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL404588; SCHEMBL11973679; BDBM50372511; NCGC00163032-01; CU-00000000243-1; 2-Nitro-N-quinolin-8-yl-4-trifluoromethyl-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(7-Methoxyquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3901591; SCHEMBL11973715; N-(7-Methoxy-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2,6-Dichloro-N-quinolin-8-ylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3911473; SCHEMBL11973000; 2,6-Dichloro-N-quinolin-8-yl-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Amino-N-(2-methylquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL258314; SCHEMBL11973111; BDBM50372519; NCGC00161710-01; NCGC00161710-02; CU-00000000254-1; 2-Amino-N-(2-methyl-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
2-Chloro-6-methyl-N-quinolin-8-ylbenzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3979305; SCHEMBL11973308; 2-Chloro-6-methyl-N-quinolin-8-yl-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(7-Isopropyl-quinolin-8-yl)-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3953717; SCHEMBL11973384; N-(7-propan-2-ylquinolin-8-yl)benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-(7-Chloroquinolin-8-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3893468; SCHEMBL11973010; N-(7-Chloro-quinolin-8-yl)-benzenesulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Compound Name |
N-[(3-Chloro-2-methylphenyl)sulfamoyl]-6-methoxyquinolin-8-amine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3894576; SCHEMBL11973804; N-(3-Chloro-2-methylphenyl)[(6-methoxyquinolin-8-yl)amino]sulfonamide
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| Activity |
IC50 = 100000 nM
|
[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | US patent application no. 20140364424A1, Novel Sulfonaminoquinoline Hepcidin Antagonists | ||||
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