Binding Site Information of Target

Content Navigation (  All   None )                                      
Target General Information
Drug Binding Sites of Target
References
Target General Information  Top
Target ID T19334 Target Info
Target Name Interleukin 21 receptor (IL21R)
Synonyms UNQ3121/PRO10273; Novel interleukin receptor; NILR; Interleukin-21 receptor; IL21 receptor; IL-21R; IL-21 receptor; CD360
Target Type Clinical trial Target
Gene Name IL21R
Biochemical Class Cytokine receptor
UniProt ID
IL21R_HUMAN
Drug Binding Sites of Target  Top
Ligand Name: Alpha-D-Mannose Ligand Info
Structure Description FAB fragment complexed with C-mannosylated tryptophan peptide PDB:6PLH
Method X-ray diffraction Resolution 1.60 Å Mutation No [1]
PDB Sequence
TWSEWSDP
Residue
Distance (Å)
GLU15
4.763
TRP16
1.494
Residue
Distance (Å)
SER17
2.414
ASP18
4.543
Click to View More Binding Site Information of This Target and Ligand Pair
References  Top
REF 1 Yeast- and antibody-based tools for studying tryptophan C-mannosylation. Nat Chem Biol. 2021 Apr;17(4):428-437.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.