Binding Site Information of Target
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T80338 | Target Info | |||
| Target Name | Activin receptor type IIB (ACVR2B) | ||||
| Synonyms | Activin receptor type2B; Activin receptor type-2B; ACTRIIB; ACTR-IIB | ||||
| Target Type | Literature-reported Target | ||||
| Gene Name | ACVR2B | ||||
| Biochemical Class | Kinase | ||||
| UniProt ID | |||||
| Drug Binding Sites of Target | Top | |||||
|---|---|---|---|---|---|---|
| Ligand Name: Adenine | Ligand Info | |||||
| Structure Description | Crystal structure of Activin receptor type II kinase domain from human | PDB:2QLU | ||||
| Method | X-ray diffraction | Resolution | 2.00 Å | Mutation | No | [1] |
| PDB Sequence |
GSLQLLEIKA
197 RGRFGCVWKA207 QLMNDFVAVK217 IFPLQDKQSW227 QSEREIFSTP237 GMKHENLLQF 247 IAAEKRGSNL257 EVELWLITAF267 HDKGSLTDYL277 KGNIITWNEL287 CHVAETMSRG 297 LSYLHEDVPW307 CRGEGHKPSI317 AHRDFKSKNV327 LLKSDLTAVL337 ADFGLAVRFE 347 PGKPPGDTHG357 QVGTRRYMAP367 EVLEGAINFQ377 RDAFLRIDMY387 AMGLVLWELV 397 SRCKAADGPV407 DEYMLPFEEE417 IGQHPSLEEL427 QEVVVHKKMR437 PTIKDHWLKH 447 PGLAQLCVTI457 EECWDHDAEA467 RLSAGCVEER477 VSLIRRS
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| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Crystal structure of activin receptor type IIB kinase domain from human at 2.0 Angstrom resolution. Protein Sci. 2007 Oct;16(10):2272-7. | ||||
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