Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T02719 Target Info
Target Name Metabotropic glutamate receptor 3 (mGluR3)
Synonyms mGLUR3; Group III metabotropic glutamate receptor; GPRC1C
Target Type Clinical trial Target
Gene Name GRM3
Biochemical Class GPCR glutamate
UniProt ID
Q14832
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-487b-3p miRNA Info
miRNA Mature AC
MIMAT0003180
Sequence aaucguacagggucauccacuu
miRNA Species Homo sapiens
Regulation Mechanism miR-487b-3p directly targets GRM3. [1]
Evidence Score (E-score) 1 +
1 Luciferase Reporter Assay; Western Blot [1]
Representative Target(s) Regulated by This miRNA Metabotropic glutamate receptor 3 (mGluR3) Target Info
GRM3_HUMAN
Polycomb complex protein BMI-1 (BMI1) Target Info
BMI1_HUMAN
References  Top
REF 1 The miR-487b-3p/GRM3/TGF signaling axis is an important regulator of colon cancer tumorigenesis. Oncogene. 2017 Jun 15;36(24):3477-3489.

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