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Target General Information |
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Target ID |
T74977 |
Target Info
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Target Name |
Dual specificity protein kinase TTK (MPS1) |
Synonyms |
Tyrosine threonine kinase; Phosphotyrosine picked threonine-protein kinase; PYT; MPS1L1 |
Target Type |
Clinical trial Target |
Gene Name |
TTK |
Biochemical Class |
Kinase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-524-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
cuacaaagggaagcacuuucuc
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
hsa-miR-524-5p regulates Ttk. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
Representative Target(s) Regulated by This miRNA |
Cyclin-dependent kinase 2 (CDK2)
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Target Info
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Dual specificity protein kinase TTK (MPS1)
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Target Info
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miRNA Mature ID |
hsa-miR-376a-5p |
miRNA Info
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miRNA Mature AC |
|
Sequence |
guagauucuccuucuaugagua
|
miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[2] |
Representative Target(s) Regulated by This miRNA |
Dual specificity protein kinase TTK (MPS1)
|
Target Info
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Monocarboxylate transporter 1 (SLC16A1)
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Target Info
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References |
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REF 1 |
Comprehensive analysis of the functional microRNA-mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression. Nucleic Acids Res. 2013 Dec;41(22):e203.
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REF 2 |
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science. 2007 Feb 23;315(5815):1137-40.
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