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Target General Information |
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Target ID |
T78311 |
Target Info
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Target Name |
Nucleus accumbens-associated protein 1 (NACC1) |
Synonyms |
NAC1; NAC-1; BTBD14B; BTB/POZ domain-containing protein 14B |
Target Type |
Literature-reported Target |
Gene Name |
NACC1 |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-331-3p |
miRNA Info
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miRNA Mature AC |
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Sequence |
gccccugggccuauccuagaa
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-331-3p and syndecan-1 axis regulates expression of NACC1 and promotes EMT in prostate cancer cells. |
[2] |
Evidence Score (E-score) |
2 |
+ |
1 |
Immunohistochemistry; RT-PCR |
[1] |
2 |
qRT-PCR |
[2] |
Representative Target(s) Regulated by This miRNA |
E2F transcription factor 1 (E2F1)
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Target Info
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Erbb2 tyrosine kinase receptor (HER2)
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Target Info
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References |
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REF 1 |
NACC1, as a Target of MicroRNA-331-3p, Regulates Cell Proliferation in Urothelial Carcinoma Cells. Cancers (Basel). 2018 Sep 21;10(10). pii: E347.
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REF 2 |
Syndecan-1 up-regulates microRNA-331-3p and mediates epithelial-to-mesenchymal transition in prostate cancer. Mol Carcinog. 2016 Sep;55(9):1378-86.
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