Target Regulator(s) Information (MicroRNA)

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Target General Information
The microRNAs (miRNAs) Regulating This Target
References
Target General Information  Top
Target ID T86679 Target Info
Target Name Adenosine A2b receptor (ADORA2B)
Synonyms Adenosine receptor A2b; A2b Adenosine receptor
Target Type Successful Target
Gene Name ADORA2B
Biochemical Class GPCR rhodopsin
UniProt ID
P29275
The microRNAs (miRNAs) Regulating This Target  Top
miRNA Mature ID hsa-miR-27b-3p miRNA Info
miRNA Mature AC
MIMAT0000419
Sequence uucacaguggcuaaguucugc
miRNA Species Homo sapiens
Evidence Score (E-score) 2 +
1 Luciferase Reporter Assay [1]
2 Luciferase Reporter Assay [2]
Representative Target(s) Regulated by This miRNA Adenosine A2b receptor (ADORA2B) Target Info
AA2BR_HUMAN
Albendazole monooxygenase (CYP3A4) Target Info
CP3A4_HUMAN
miRNA Mature ID hsa-miR-128-3p miRNA Info
miRNA Mature AC
MIMAT0000424
Sequence ucacagugaaccggucucuuu
miRNA Species Homo sapiens
Regulation Mechanism The overexpression of miR-128-3p by mature miRNA precursor transfection resulted in the changed mRNA level of target ADORA2B. [1]
Evidence Score (E-score) 1 +
1 qRT-PCR; Luciferase Reporter Assay [1]
Representative Target(s) Regulated by This miRNA Adenosine A2b receptor (ADORA2B) Target Info
AA2BR_HUMAN
NT-3 growth factor receptor (TrkC) Target Info
NTRK3_HUMAN
References  Top
REF 1 Adenosine 2B receptor expression is post-transcriptionally regulated by microRNA. J Biol Chem. 2010 Jun 11;285(24):18184-90.
REF 2 MiR-27b regulates podocyte survival through targeting adenosine receptor 2B in podocytes from non-human primate. Cell Death Dis. 2018 Nov 14;9(11):1133.

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