Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T07303 Target Info
Target Name Vascular endothelial growth factor receptor 3 (FLT-4)
Synonyms VEGFR3; VEGFR-3; VEGF-3 receptor; Tyrosine-protein kinase receptor FLT4; Fms-like tyrosine kinase 4
Target Type Successful Target
Gene Name FLT4
Biochemical Class Kinase
UniProt ID
VGFR3_HUMAN 
Target Interacting Proteins  Top
Other proteins [+] 1 Other proteins +
Interacting Protein Name SHC-transforming protein 1 (SHC1) Interacting Protein Interacting Protein Info
UniProt ID
SHC1_HUMAN 
Synonyms SHC; SHCA
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Affinity Capture-Western [2]
3 Reconstituted Complex [1]
4 Reconstituted Complex [2]
References  Top
REF 1 Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors. Oncogene. 1994 Dec;9(12):3545-55.
REF 2 Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase. J Biol Chem. 1996 May 31;271(22):12956-63.

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