Content Navigation
( All
None )
| Target General Information |
Top |
| Target ID |
T10877 |
Target Info
|
| Target Name |
Cyclic ADP-ribose hydrolase 1 (CD38) |
| Synonyms |
cADPr hydrolase 1; T10; Cyclic ADPribose hydrolase 1; ADPribosyl cyclase 1; ADPRC 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase 1; 2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-ADP-ribosyl cyclase |
| Target Type |
Successful Target |
| Gene Name |
CD38 |
| Biochemical Class |
Glycosylase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acyltransferases |
[+] 1 Acyltransferases |
+ |
| Interacting Target Name |
Signal transduction protein CBL (CBL) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
RNF55; RING-type E3 ubiquitin transferase CBL; RING finger protein 55; Proto-oncogene c-CBL; E3 ubiquitin-protein ligase CBL; C-Cbl; CBL2; Casitas B-lineage lymphoma proto-oncogene |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Fluorescence Resonance Energy Transfer |
[2] |
| References |
Top |
| REF 1 |
c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells. Cancer Res. 2008 Nov 1;68(21):8761-9.
|
| REF 2 |
c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrest. J Biol Chem. 2009 Sep 18;284(38):25664-77.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
