Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T15797 Target Info
Target Name SET and MYND domain-containing protein 2 (SMYD2)
Synonyms Nlysine methyltransferase SMYD2; N-lysine methyltransferase SMYD2; Lysine Nmethyltransferase 3C; Lysine N-methyltransferase 3C; KMT3C; Histone methyltransferase SMYD2; HSKMB; HSKM-B
Target Type Preclinical Target
Gene Name SMYD2
Biochemical Class Methyltransferase
UniProt ID
SMYD2_HUMAN 
Target Interacting Proteins  Top
Heat shock proteins [+] 1 Heat shock proteins +
Pore-forming toxins [+] 1 Pore-forming toxins +
Other proteins [+] 1 Other proteins +
References  Top
REF 1 The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. Mol Cell Proteomics. 2008 Mar;7(3):560-72.
REF 2 Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2. J Mol Cell Biol. 2011 Oct;3(5):301-8.
REF 3 Repression of p53 activity by Smyd2-mediated methylation. Nature. 2006 Nov 30;444(7119):629-32.
REF 4 Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol. 2007;3:89.

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