Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T16117 Target Info
Target Name Nitric-oxide synthase brain (NOS1)
Synonyms Peptidyl-cysteine S-nitrosylase NOS1; Nitric oxide synthase, brain; Neuronal NOS; NOS, type I; NOS type I; NNOS; NC-NOS; N-NOS; BNOS
Target Type Clinical trial Target
Gene Name NOS1
Biochemical Class Paired donor oxygen oxidoreductase
UniProt ID
NOS1_HUMAN 
Target Interacting Proteins  Top
Microtubule-associated [+] 1 Microtubule-associated +
Interacting Target Name Presynaptic density protein 95 (DLG4) Clinical trial Target Interacting Protein Info
UniProt ID
DLG4_HUMAN 
Synonyms Synapse-associated protein 90; SAP-90; SAP90; PSD-95; PSD95; Postsynaptic density-95; Postsynaptic density protein 95; Disks large homolog 4; Discs, large homolog 4
Evidence Score (E-score) 4 Experimental Evidences +
1 Affinity Capture-Western [1]
2 Affinity Capture-Western [2]
3 Reconstituted Complex [2]
4 Yeast two hybrid [2]
References  Top
REF 1 CAPON: a protein associated with neuronal nitric oxide synthase that regulates its interactions with PSD95. Neuron. 1998 Jan;20(1):115-24.
REF 2 Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell. 1996 Mar 8;84(5):757-67.

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