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| Target General Information |
Top |
| Target ID |
T16691 |
Target Info
|
| Target Name |
5-HT 6 receptor (HTR6) |
| Synonyms |
Serotonin receptor 6; 5-hydroxytryptamine receptor 6; 5-HT6 receptor; 5-HT6; 5-HT-6 |
| Target Type |
Clinical trial Target |
| Gene Name |
HTR6 |
| Biochemical Class |
GPCR rhodopsin |
| UniProt ID |
|
| Target Interacting Proteins |
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| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Protein Name |
Neurofibromin (NF1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
NFNS; VRNF; WSS |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[1] |
| 3 |
Affinity Capture-Western |
[2] |
| References |
Top |
| REF 1 |
5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia. EMBO Mol Med. 2012 Oct;4(10):1043-56.
|
| REF 2 |
Physical interaction between neurofibromin and serotonin 5-HT6 receptor promotes receptor constitutive activity. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):12310-12315.
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