| References |
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| REF 1 |
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Mol Cell Biol. 2004 Jul;24(13):5639-49.
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| REF 2 |
SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53. Cell. 2013 Jul 18;154(2):297-310.
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| REF 3 |
Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases. J Biol Chem. 2012 Aug 10;287(33):27275-89.
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| REF 4 |
Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34+ cells. Oncogene. 2010 Sep 9;29(36):5019-31.
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| REF 5 |
Somatic cancer mutations in the MLL1 histone methyltransferase modulate its enzymatic activity and dependence on the WDR5/RBBP5/ASH2L complex. Mol Oncol. 2017 Apr;11(4):373-387.
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| REF 6 |
WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket. J Biol Chem. 2008 Dec 12;283(50):35258-64.
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| REF 7 |
Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inh... J Biol Chem. 2016 Oct 21;291(43):22357-22372.
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| REF 8 |
A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes. J Mol Biol. 2014 Jun 12;426(12):2283-99.
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| REF 9 |
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8342-7.
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| REF 10 |
ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol Cell. 2002 Nov;10(5):1119-28.
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| REF 11 |
Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation. J Biol Chem. 2014 Jan 10;289(2):868-84.
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| REF 12 |
Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 2010 Jun 25;141(7):1183-94.
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| REF 13 |
Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription. J Mol Biol. 2010 Jul 9;400(2):137-44.
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| REF 14 |
Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells. Mol Cell Biol. 2001 May;21(10):3589-97.
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| REF 15 |
Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization. Cancer Res. 2008 Aug 1;68(15):6199-207.
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| REF 16 |
LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nat Commun. 2013;4:1531.
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| REF 17 |
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell. 2005 Jun 17;121(6):873-85.
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| REF 18 |
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein. Mol Cell Biol. 2001 Apr;21(7):2249-58.
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| REF 19 |
Cooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation do... J Biol Chem. 2002 Nov 8;277(45):43168-74.
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| REF 20 |
Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll. Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6629-34.
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| REF 21 |
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell. 2005 Oct 21;123(2):207-18.
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| REF 22 |
MLL associates specifically with a subset of transcriptionally active target genes. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14765-70.
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| REF 23 |
Interaction of MLL amino terminal sequences with menin is required for transformation. Cancer Res. 2007 Aug 1;67(15):7275-83.
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| REF 24 |
The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers. Mol Cell Biol. 2013 Dec;33(23):4745-54.
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| REF 25 |
The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. Genes Dev. 2006 Mar 1;20(5):586-600.
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| REF 26 |
A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription. Cancer Cell. 2010 Feb 17;17(2):198-212.
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| REF 27 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
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| REF 28 |
Divergent hTAFII31-binding motifs hidden in activation domains. J Biol Chem. 2000 May 26;275(21):15912-6.
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