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REF 1 |
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity. 2011 Sep 23;35(3):426-40.
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REF 2 |
Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Mol Cell. 1998 Mar;1(4):507-18.
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REF 3 |
Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1. Mol Cell Biol. 1998 Mar;18(3):1359-68.
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REF 4 |
Ser386 phosphorylation of transcription factor IRF-3 induces dimerization and association with CBP/p300 without overall conformational change. Genes Cells. 2010 Aug;15(8):901-10.
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Direct involvement of CREB-binding protein/p300 in sequence-specific DNA binding of virus-activated interferon regulatory factor-3 holocomplex. J Biol Chem. 2002 Jun 21;277(25):22304-13.
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TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response. J Immunol. 2009 Mar 15;182(6):3782-92.
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The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3. J Immunol. 2008 Aug 1;181(3):1780-6.
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Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells. Mol Biol Cell. 2006 Mar;17(3):1461-71.
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Tom70 mediates activation of interferon regulatory factor 3 on mitochondria. Cell Res. 2010 Sep;20(9):994-1011.
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NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat Immunol. 2012 Mar 4;13(4):387-95.
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Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nat Cell Biol. 2017 Apr;19(4):362-374.
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Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation. Science. 2015 Mar 13;347(6227):aaa2630.
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Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat Neurosci. 2015 May;18(5):631-6.
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Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. J Biol Chem. 2007 Nov 2;282(44):32208-21.
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Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction. Virology. 2007 Apr 10;360(2):305-21.
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Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression. Mol Cell Biol. 2015 May;35(10):1660-72.
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REF 17 |
Activation of interferon regulatory factor 3 in response to DNA-damaging agents. J Biol Chem. 1999 Oct 22;274(43):30686-9.
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Oxidized low density lipoprotein blocks lipopolysaccharide-induced interferon beta synthesis in human macrophages by interfering with IRF3 activation. J Biol Chem. 2004 Jul 2;279(27):28781-8.
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REF 19 |
Thogoto virus ML protein suppresses IRF3 function. Virology. 2005 Jan 5;331(1):63-72.
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REF 20 |
Crystal structure of IRF-3 in complex with CBP. Structure. 2005 Sep;13(9):1269-77.
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REF 21 |
Analysis of functional domains of interferon regulatory factor 7 and its association with IRF-3. Virology. 2001 Feb 15;280(2):273-82.
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REF 22 |
Tetraspanin 6 (TSPAN6) negatively regulates retinoic acid-inducible gene I-like receptor-mediated immune signaling in a ubiquitination-dependent manner. J Biol Chem. 2012 Oct 5;287(41):34626-34.
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REF 23 |
VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell. 2005 Sep 16;19(6):727-40.
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REF 24 |
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep. 2008 Sep;9(9):930-6.
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