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Protein General Information |
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Full Name |
Inhibitor of nuclear factor kappa-B kinase (IKK)
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UniProt ID |
Family
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Gene Name |
NO-GeName
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Interacting TTD Target Information |
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Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
Interferon regulatory factor 3 (IRF3) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKK kinase-mediated antiviral response. Immunity. 2014 Jun 19;40(6):880-95.
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REF 2 |
The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep. 2008 Sep;9(9):930-6.
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