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| Target General Information |
Top |
| Target ID |
T50429 |
Target Info
|
| Target Name |
Peptidyl arginine deiminase type IV (PADI4) |
| Synonyms |
Protein-arginine deiminase type-4; Protein-arginine deiminase type IV; Peptidylarginine deiminase IV; PDI5; PADI5; PAD4; HL-60 PAD |
| Target Type |
Literature-reported Target |
| Gene Name |
PADI4 |
| Biochemical Class |
Carbon-nitrogen hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Pore-forming toxins |
[+] 1 Pore-forming toxins |
+ |
| Interacting Target Name |
Cellular tumor antigen p53 (TP53) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Tumor suppressor p53; Phosphoprotein p53; P53; Antigen NY-CO-13 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Co-localization |
[1] |
| 4 |
Reconstituted Complex |
[1] |
| References |
Top |
| REF 1 |
Regulation of p53 target gene expression by peptidylarginine deiminase 4. Mol Cell Biol. 2008 Aug;28(15):4745-58.
|
| REF 2 |
Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression. Oncogene. 2010 May 27;29(21):3153-62.
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