| References |
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Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 2 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
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Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction. FEBS J. 2006 Aug;273(16):3837-49.
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Expression of B-crystallin overrides the anti-apoptotic activity of XIAP. Neuro Oncol. 2012 Nov;14(11):1332-45.
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Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12815-9.
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Structural basis for the inhibition of caspase-3 by XIAP. Cell. 2001 Mar 9;104(5):791-800.
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| REF 7 |
A single BIR domain of XIAP sufficient for inhibiting caspases. J Biol Chem. 1998 Apr 3;273(14):7787-90.
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X-linked IAP is a direct inhibitor of cell-death proteases. Nature. 1997 Jul 17;388(6639):300-4.
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| REF 9 |
IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS Pathog. 2006 Oct;2(10):e114.
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| REF 10 |
The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing. J Biol Chem. 2009 May 8;284(19):12772-82.
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The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 1997 Dec 1;16(23):6914-25.
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Overexpression of the truncated form of Livin reveals a complex interaction with caspase-3. Int J Oncol. 2013 Jun;42(6):2037-45.
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| REF 13 |
Livin, a novel inhibitor of apoptosis protein family member. J Biol Chem. 2001 Feb 2;276(5):3238-46.
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| REF 14 |
Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9. Biochem J. 2007 Jul 1;405(1):11-9.
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The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9. J Biol Chem. 2005 Jan 7;280(1):174-82.
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| REF 16 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 1997 Jun;6(6):751-63.
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MRIT, a novel death-effector domain-containing protein, interacts with caspases and BclXL and initiates cell death. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11333-8.
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| REF 19 |
A 60 kd MDM2 isoform is produced by caspase cleavage in non-apoptotic tumor cells. Oncogene. 1998 Nov 19;17(20):2629-36.
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Proteolytic cleavage of the mdm2 oncoprotein during apoptosis. J Biol Chem. 1997 Sep 5;272(36):22966-73.
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Autoactivation of the MDM2 E3 ligase by intramolecular interaction. Mol Cell Biol. 2014 Aug;34(15):2800-10.
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Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells. Eur J Biochem. 1998 Oct 1;257(1):242-8.
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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade. Mol Cell. 1998 Mar;1(4):553-63.
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Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis. Oncogene. 1999 Feb 4;18(5):1131-8.
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Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells. Biochem J. 2002 May 15;364(Pt 1):41-7.
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Caspase-mediated cleavage of actin-binding and SH3-domain-containing proteins cortactin, HS1, and HIP-55 during apoptosis. Biochem Biophys Res Commun. 2001 Nov 9;288(4):981-9.
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An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7. Biochemistry. 2001 Jan 30;40(4):1117-23.
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IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 1998 Dec 1;58(23):5315-20.
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