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| Target General Information |
Top |
| Target ID |
T58238 |
Target Info
|
| Target Name |
Activation B7-1 antigen (CD80) |
| Synonyms |
T-lymphocyte activation antigen CD80; LAB7; CTLA-4 counter-receptor B7.1; CD28LG1; CD28LG; BB1; B7 |
| Target Type |
Successful Target |
| Gene Name |
CD80 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Other proteins |
[+] 1 Other proteins |
+ |
| Interacting Target Name |
Cytotoxic T-lymphocyte protein 4 (CTLA-4) |
Successful Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Cytotoxic T-lymphocyte-associated antigen 4; CD152 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Co-crystal Structure |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses. Nature. 2001 Mar 29;410(6828):608-11.
|
| REF 2 |
A secreted protein microarray platform for extracellular protein interaction discovery. Anal Biochem. 2012 Jan 15;420(2):127-38.
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