| References |
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| REF 1 |
Epidermal growth factor stimulation of the ACK1/Dbl pathway in a Cdc42 and Grb2-dependent manner. Biochem Biophys Res Commun. 2001 Jun 8;284(2):470-7.
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| REF 2 |
HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK. Mol Cell Biol. 2010 Mar;30(6):1541-54.
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| REF 3 |
The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome. J Cell Sci. 2014 Mar 1;127(Pt 5):994-1006.
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| REF 4 |
Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and ... J Comp Neurol. 2005 Sep 19;490(2):119-32.
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| REF 5 |
A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK. J Biol Chem. 2017 Jul 7;292(27):11361-11373.
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| REF 6 |
Identification of the region in Cdc42 that confers the binding specificity to activated Cdc42-associated kinase. J Biol Chem. 2004 Jul 16;279(29):30507-13.
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| REF 7 |
Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy. Ann Neurol. 2013 Sep;74(3):496-501.
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| REF 8 |
HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cell Signal. 2017 Nov;39:9-17.
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| REF 9 |
Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation. FEBS Lett. 1996 May 20;386(2-3):230-4.
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| REF 10 |
The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1). Biochem J. 2012 Jul 15;445(2):255-64.
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| REF 11 |
The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation. Biochem J. 2011 Apr 15;435(2):355-64.
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| REF 12 |
A human MAP kinase interactome. Nat Methods. 2010 Oct;7(10):801-5.
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| REF 13 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 14 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001.
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| REF 15 |
Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox. Cancer Res. 2005 Nov 15;65(22):10514-23.
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| REF 16 |
Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor. J Proteome Res. 2008 Mar;7(3):1067-77.
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| REF 17 |
Cytoplasmic ACK1 interaction with multiple receptor tyrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signaling. J Biol Chem. 2009 Dec 11;284(50):34954-63.
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| REF 18 |
TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells. Breast Cancer Res. 2008;10(2):R36.
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| REF 19 |
Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas. J Biol Chem. 2006 Dec 8;281(49):37527-35.
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| REF 20 |
Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2. J Biol Chem. 2009 Mar 20;284(12):8185-94.
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| REF 21 |
Activated cdc42-associated kinase is up-regulated in non-small-cell lung cancer and necessary for FGFR-mediated AKT activation. Mol Carcinog. 2016 May;55(5):853-63.
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| REF 22 |
PDGFR--activated ACK1-AKT signaling promotes glioma tumorigenesis. Int J Cancer. 2015 Apr 15;136(8):1769-80.
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| REF 23 |
The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors. J Biol Chem. 2001 May 25;276(21):18392-8.
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| REF 24 |
Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor. EMBO J. 2009 Nov 18;28(22):3485-99.
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| REF 25 |
Nephrocystin-1 interacts directly with Ack1 and is expressed in human collecting duct. Biochem Biophys Res Commun. 2008 Jul 11;371(4):877-82.
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