| References |
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| REF 1 |
Charting the molecular network of the drug target Bcr-Abl. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7414-9.
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| REF 2 |
Detection in primary chronic myeloid leukaemia cells of p210BCR-ABL1 in complexes with adaptor proteins CBL, CRKL, and GRB2. Genes Chromosomes Cancer. 2006 Dec;45(12):1121-9.
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| REF 3 |
Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor. Oncogene. 2001 Jul 5;20(30):4058-69.
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| REF 4 |
Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G. J Biol Chem. 1996 Apr 5;271(14):8435-42.
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| REF 5 |
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Mol Cell Biol. 2002 Jun;22(12):4020-32.
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| REF 6 |
Detection of transient protein-protein interactions by bimolecular fluorescence complementation: the Abl-SH3 case. Proteomics. 2007 Apr;7(7):1023-36.
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| REF 7 |
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16691-6.
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| REF 8 |
Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease. J Neurosci. 2011 Jan 5;31(1):157-63.
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| REF 9 |
The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr. J Biol Chem. 1997 Dec 26;272(52):33260-70.
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| REF 10 |
Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites. Genes Dev. 1994 Apr 1;8(7):783-95.
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| REF 11 |
Requirement of multiple SH3 domains of Nck for ligand binding. Cell Signal. 1999 Apr;11(4):253-62.
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| REF 12 |
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat Cell Biol. 2005 Mar;7(3):278-85.
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| REF 13 |
Interaction of BCR-ABL with the retinoblastoma protein in Philadelphia chromosome-positive cell lines. Int J Hematol. 1997 Feb;65(2):115-21.
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| REF 14 |
Disruption of retinoblastoma protein function by coexpression of its C pocket fragment. Genes Dev. 1995 Jan 1;9(1):31-46.
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| REF 15 |
Physical and functional interaction between hMSH5 and c-Abl. Cancer Res. 2006 Jan 1;66(1):151-8.
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| REF 16 |
Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis. Exp Cell Res. 2009 Aug 15;315(14):2420-32.
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| REF 17 |
A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells. Blood. 1999 Apr 15;93(8):2707-20.
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| REF 18 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001.
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| REF 19 |
Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. Blood. 2011 Mar 17;117(11):3151-62.
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| REF 20 |
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J Biol Chem. 1999 Apr 30;274(18):12748-52.
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| REF 21 |
Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status. Cancer Res. 2007 Apr 1;67(7):3010-7.
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| REF 22 |
Interaction between ATM protein and c-Abl in response to DNA damage. Nature. 1997 May 29;387(6632):520-3.
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| REF 23 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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| REF 24 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
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| REF 25 |
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature. 2006 Jan 12;439(7073):168-74.
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| REF 26 |
Reciprocal regulation of Abl and receptor tyrosine kinases. Cell Signal. 2009 Jul;21(7):1143-50.
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| REF 27 |
Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor. J Neurosci Res. 2000 Feb 1;59(3):356-64.
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| REF 28 |
Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop. FEBS Lett. 2000 Mar 3;469(1):72-6.
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| REF 29 |
A positive role for c-Abl in Atm and Atr activation in DNA damage response. Cell Death Differ. 2011 Jan;18(1):5-15.
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| REF 30 |
Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem. 1999 Dec 31;274(53):37538-43.
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| REF 31 |
Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response. J Biol Chem. 2003 Apr 11;278(15):12961-7.
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| REF 32 |
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway. EMBO J. 1994 Feb 15;13(4):764-73.
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| REF 33 |
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. Cell. 1991 Jul 12;66(1):161-71.
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| REF 34 |
Identification of two SH3-binding motifs in the regulatory subunit of phosphatidylinositol 3-kinase. J Biol Chem. 1994 Jan 21;269(3):1927-33.
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| REF 35 |
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature. 1999 Jun 24;399(6738):814-7.
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| REF 36 |
Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation. EMBO J. 2002 Jul 15;21(14):3715-27.
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| REF 37 |
Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1749-54.
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| REF 38 |
Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk. Immunity. 2008 Oct 17;29(4):578-88.
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| REF 39 |
c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J. 1994 May 15;13(10):2341-51.
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| REF 40 |
The SH2-containing adapter protein GRB10 interacts with BCR-ABL. Oncogene. 1998 Aug 27;17(8):941-8.
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| REF 41 |
Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation. Blood. 1997 Jan 1;89(1):297-306.
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| REF 42 |
A BCR-ABL mutant lacking direct binding sites for the GRB2, CBL and CRKL adapter proteins fails to induce leukemia in mice. PLoS One. 2009 Oct 13;4(10):e7439.
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| REF 43 |
Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok. Cell. 1997 Jan 24;88(2):205-11.
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| REF 44 |
Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins. J Biol Chem. 1998 Nov 27;273(48):32360-8.
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| REF 45 |
Isolation and characterization of e3B1, an eps8 binding protein that regulates cell growth. Oncogene. 1997 Jan 16;14(2):233-41.
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| REF 46 |
Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1. Biochim Biophys Acta. 2008 May;1783(5):737-47.
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| REF 47 |
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. BMC Cancer. 2016 May 26;16:335.
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