Target Interacting Protein Information

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Target General Information
Target Interacting Proteins
References
Target General Information  Top
Target ID T68211 Target Info
Target Name High mobility group protein HMG-I/Y (HMGA1)
Synonyms High mobility group protein R; High mobility group protein HMG-I/HMG-Y; High mobility group protein A1; High mobility group AT-hook protein 1; HMGIY; HMG-I(Y)
Target Type Literature-reported Target
Gene Name HMGA1
UniProt ID
HMGA1_HUMAN 
Target Interacting Proteins  Top
Kinases [+] 1 Kinases +
Nuclear hormone receptors [+] 1 Nuclear hormone receptors +
Transcription regulators [+] 2 Transcription regulators +
References  Top
REF 1 A bead-based approach for large-scale identification of in vitro kinase substrates. Proteomics. 2011 Dec;11(24):4632-7.
REF 2 The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists. Endocr Relat Cancer. 2008 Mar;15(1):325-35.
REF 3 Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor. J Biol Chem. 1999 Aug 6;274(32):22563-8.
REF 4 A nucleoprotein complex containing Sp1, C/EBP beta, and HMGI-Y controls human insulin receptor gene transcription. Mol Cell Biol. 2003 Apr;23(8):2720-32.
REF 5 HMGA1 protein is a positive regulator of the insulin-like growth factor-I receptor gene. Eur J Cancer. 2010 Jul;46(10):1919-26.
REF 6 Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome. Mol Cell. 1998 Oct;2(4):457-67.

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