| References |
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| REF 1 |
Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor. Oncogene. 2001 Jul 5;20(30):4058-69.
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| REF 2 |
Characterization of Cbl-Nck and Nck-Pak1 interactions in myeloid FcgammaRII signaling. Exp Cell Res. 1998 Dec 15;245(2):330-42.
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| REF 3 |
Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamics. Nat Commun. 2013;4:2863.
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| REF 4 |
Abl family kinases and Cbl cooperate with the Nck adaptor to modulate Xenopus development. J Biol Chem. 2000 Nov 17;275(46):36472-8.
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| REF 5 |
The kinase-deficient Src acts as a suppressor of the Abl kinase for Cbl phosphorylation. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6439-44.
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| REF 6 |
The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors. Mol Cell Biol. 1992 Dec;12(12):5824-33.
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| REF 7 |
Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck. J Biol Chem. 1999 Feb 26;274(9):5542-9.
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| REF 8 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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| REF 9 |
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature. 2006 Jan 12;439(7073):168-74.
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| REF 10 |
Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor. Oncogene. 1997 Oct 9;15(15):1823-32.
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| REF 11 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
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| REF 12 |
Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling. J Biol Chem. 2001 Jun 1;276(22):18908-14.
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| REF 13 |
SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome. Cell Commun Signal. 2012 Sep 14;10(1):27.
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| REF 14 |
Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase. Mol Cell Biol. 1999 Feb;19(2):1359-68.
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| REF 15 |
SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1. J Biol Chem. 1997 Oct 31;272(44):27804-11.
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| REF 16 |
A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT. EMBO J. 2001 Feb 1;20(3):457-65.
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| REF 17 |
Interaction of the Nck adapter protein with p21-activated kinase (PAK1). J Biol Chem. 1996 Oct 18;271(42):25746-9.
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| REF 18 |
Requirement of multiple SH3 domains of Nck for ligand binding. Cell Signal. 1999 Apr;11(4):253-62.
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| REF 19 |
Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites. Genes Dev. 1994 Apr 1;8(7):783-95.
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| REF 20 |
Nck-2 interacts with focal adhesion kinase and modulates cell motility. Int J Biochem Cell Biol. 2002 Jul;34(7):791-805.
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| REF 21 |
Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes. J Exp Med. 1996 Oct 1;184(4):1365-75.
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| REF 22 |
Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling. J Biol Chem. 1996 Nov 15;271(46):28772-6.
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| REF 23 |
Characterization of interactions of Nck with Sos and dynamin. Cell Signal. 1999 Jan;11(1):25-9.
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| REF 24 |
Binding of NCK to SOS and activation of ras-dependent gene expression. Mol Cell Biol. 1995 Mar;15(3):1169-74.
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| REF 25 |
Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor. J Biol Chem. 1996 Oct 11;271(41):25533-8.
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| REF 26 |
The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68. Oncogene. 1997 Jan 16;14(2):223-31.
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| REF 27 |
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome. PLoS One. 2012;7(6):e38540.
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| REF 28 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
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| REF 29 |
Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway. J Biol Chem. 2001 Jul 13;276(28):26448-52.
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| REF 30 |
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 2016 Feb 11;164(4):805-17.
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| REF 31 |
Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. J Cell Biol. 2000 Apr 3;149(1):181-94.
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| REF 32 |
Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains. Mol Cell Biol. 1995 Oct;15(10):5725-31.
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| REF 33 |
Multiple interactions of the cytosolic polyproline region of the CD95 ligand: hints for the reverse signal transduction capacity of a death factor. FEBS Lett. 2001 Dec 7;509(2):255-62.
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| REF 34 |
Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells. EMBO J. 1997 Jul 1;16(13):3877-88.
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| REF 35 |
Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity. Cell Signal. 2011 Oct;23(10):1651-8.
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| REF 36 |
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation. J Biol Chem. 2012 Mar 9;287(11):8194-204.
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| REF 37 |
Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes. Eur J Immunol. 1999 Apr;29(4):1068-75.
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