Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | GTPase activating protein (RASA1) | Literature-reported | Target Info | ||
| UniProt ID | RASA1_HUMAN | ||||
| Gene Name | RASA1 | ||||
| Gene ID | 5921 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Epidermal growth factor receptor (EGFR) | Target Info | PPI Info | [1] | |
| Interacting Clinical trial Target(s) | NCK adaptor protein 1 (NCK1) | Target Info | PPI Info | [2] | |
| Interacting Literature-reported Target(s) | Focal adhesion kinase 2 (PTK2B) | Target Info | PPI Info | [3] | |
| GTPase HRas (HRAS) | Target Info | PPI Info | [4] | ||
| GAP-associated tyrosine phosphoprotein p62 (KHDRBS1) | Target Info | PPI Info | [5] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature. 2006 Jan 12;439(7073):168-74. | ||||
| REF 2 | Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells. EMBO J. 1997 Jul 1;16(13):3877-88. | ||||
| REF 3 | Identification of a novel protein complex containing annexin VI, Fyn, Pyk2, and the p120(GAP) C2 domain. FEBS Lett. 2000 Mar 3;469(1):88-92. | ||||
| REF 4 | EGFR phosphorylates FAM129B to promote Ras activation. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):644-9. | ||||
| REF 5 | Sam68 is a docking protein linking GAP and PI3K in insulin receptor signaling. Mol Cell Endocrinol. 2001 Oct 25;183(1-2):113-21. | ||||
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