| References |
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| REF 1 |
Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem. 2006 Dec 8;281(49):38061-70.
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| REF 2 |
Reciprocal cross-regulation between RNF41 and USP8 controls cytokine receptor sorting and processing. J Cell Sci. 2013 Aug 15;126(Pt 16):3770-81.
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| REF 3 |
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. J Biol Chem. 2006 May 5;281(18):12618-24.
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| REF 4 |
Regulation of epidermal growth factor receptor ubiquitination and trafficking by the USP8TAM complex. J Biol Chem. 2010 Nov 5;285(45):34909-21.
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| REF 5 |
A deubiquitinating enzyme UBPY interacts with the Src homology 3 domain of Hrs-binding protein via a novel binding motif PX(V/I)(D/N)RXXKP. J Biol Chem. 2000 Dec 1;275(48):37481-7.
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| REF 6 |
Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion. Biochem Biophys Res Commun. 2018 May 15;499(3):635-641.
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| REF 7 |
The ubiquitin-specific protease USP8 is critical for the development and homeostasis of T cells. Nat Immunol. 2015 Sep;16(9):950-60.
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| REF 8 |
A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling. Curr Biol. 2002 Aug 6;12(15):1336-41.
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| REF 9 |
Inhibition of Ubiquitin-specific Peptidase 8 Suppresses Growth of Gefitinib-resistant Non-small Cell Lung Cancer Cells by Inducing Apoptosis. J Cancer Prev. 2015 Mar;20(1):57-63.
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| REF 10 |
Cbl and Itch binding sites in ERBB4 CYT-1 and CYT-2 mediate K48- and K63-polyubiquitination, respectively. Cell Signal. 2013 Feb;25(2):470-8.
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| REF 11 |
Mutations in the deubiquitinase gene USP8 cause Cushing's disease. Nat Genet. 2015 Jan;47(1):31-8.
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| REF 12 |
The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types. Chem Biol. 2011 Dec 23;18(12):1550-61.
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| REF 13 |
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis. EMBO J. 2015 Feb 3;34(3):307-25.
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| REF 14 |
Divergence in Ubiquitin Interaction and Catalysis among the Ubiquitin-Specific Protease Family Deubiquitinating Enzymes. Biochemistry. 2016 Aug 23;55(33):4708-19.
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| REF 15 |
The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degrada... J Biol Chem. 2007 Oct 19;282(42):30929-37.
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| REF 16 |
A strategy for modulation of enzymes in the ubiquitin system. Science. 2013 Feb 1;339(6119):590-5.
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| REF 17 |
Ab initio protein modelling reveals novel human MIT domains. FEBS Lett. 2009 Mar 4;583(5):872-8.
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