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| Protein General Information |
Top |
| Full Name |
Signal transducing adapter molecule 1 (STAM)
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| UniProt ID |
STAM1_HUMAN
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| Gene Name |
STAM
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| Gene ID |
8027
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
C-X-C chemokine receptor type 4 (CXCR4) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[2] |
| Interacting Literature-reported Target(s) |
E3 ubiquitin protein ligase Itchy (ITCH) |
Target Info
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PPI Info
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[3] |
| Interacting Preclinical Target(s) |
Ubiquitin isopeptidase Y (USP8) |
Target Info
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PPI Info
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[4] |
| References |
Top |
| REF 1 |
Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling. J Biol Chem. 2012 Mar 16;287(12):9013-27.
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| REF 2 |
Conformational and dynamic changes at the interface contribute to ligand binding by ubiquitin. Biochemistry. 2012 Oct 16;51(41):8111-24.
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| REF 3 |
Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners. EMBO Rep. 2015 Dec;16(12):1699-712.
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| REF 4 |
The ubiquitin isopeptidase UBPY regulates endosomal ubiquitin dynamics and is essential for receptor down-regulation. J Biol Chem. 2006 May 5;281(18):12618-24.
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