Target Interacting Protein Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T92328 | Target Info | |||
| Target Name | Ryanodine receptor 1 (RYR1) | ||||
| Synonyms | Type 1 ryanodine receptor; Skeletal muscle-type ryanodine receptor; Skeletal muscle ryanodine receptor; Skeletal muscle calcium release channel; RyR1; RyR; RYR-1; RYDR; Cardiac muscleryanodine receptor-calcium release channel; Cardiac muscle-type ryanodine receptor; Brain-type ryanodine receptor; Brain ryanodine receptor-calcium release channel | ||||
| Target Type | Discontinued Target | ||||
| Gene Name | RYR1 | ||||
| Biochemical Class | Ryanodine-inositol 1,4,5-triphosphate receptor calcium channel | ||||
| UniProt ID | |||||
| Target Interacting Proteins | Top | ||||
|---|---|---|---|---|---|
| Auxiliary transporters | [+] 1 Auxiliary transporters | + | |||
| Isomerases | [+] 1 Isomerases | + | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Functional interaction of the cytoplasmic domain of triadin with the skeletal ryanodine receptor. J Biol Chem. 1999 Apr 30;274(18):12278-83. | ||||
| REF 2 | Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin. J Biol Chem. 2004 Feb 20;279(8):6994-7000. | ||||
| REF 3 | FKBP12 binding to RyR1 modulates excitation-contraction coupling in mouse skeletal myotubes. J Biol Chem. 2003 Jun 20;278(25):22600-8. | ||||
| REF 4 | Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor. Biochem J. 2001 Mar 1;354(Pt 2):413-22. | ||||
| REF 5 | FKBP12 binding modulates ryanodine receptor channel gating. J Biol Chem. 2001 May 18;276(20):16931-5. | ||||
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