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| Target General Information |
Top |
| Target ID |
T95660 |
Target Info
|
| Target Name |
Twist-related protein 1 (TWIST1) |
| Synonyms |
bHLHa38; TWIST; H-twist; Class A basic helix-loop-helix protein 38 |
| Target Type |
Literature-reported Target |
| Gene Name |
TWIST1 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Pore-forming toxins |
[+] 1 Pore-forming toxins |
+ |
| Interacting Target Name |
Cellular tumor antigen p53 (TP53) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Tumor suppressor p53; Phosphoprotein p53; P53; Antigen NY-CO-13 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
A "twist box" code of p53 inactivation: twist box: p53 interaction promotes p53 degradation. Cancer Cell. 2012 Sep 11;22(3):404-15.
|
| REF 2 |
Twist and p53 reciprocally regulate target genes via direct interaction. Oncogene. 2008 Sep 18;27(42):5543-53.
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