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| Target General Information |
Top |
| Target ID |
T98913 |
Target Info
|
| Target Name |
Granulocyte colony-stimulating factor receptor (G-CSF-R) |
| Synonyms |
c-fms; GCSFR; GCSF receptor; G-CSF receptor; Fms proto-oncogene; CD114 |
| Target Type |
Successful Target |
| Gene Name |
CSF3R |
| Biochemical Class |
Cytokine receptor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Adapter proteins |
[+] 1 Adapter proteins |
+ |
| Interacting Protein Name |
Growth factor receptor-bound protein 2 (GRB2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
SH2/SH3 adapter GRB2; Protein Ash; Growth factor receptor-bound protein 2; ASH; Adapter protein GRB2 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Far Western |
[1] |
| 3 |
Protein-peptide |
[2] |
| 4 |
Reconstituted Complex |
[2] |
| References |
Top |
| REF 1 |
Direct binding of Shc, Grb2, SHP-2 and p40 to the murine granulocyte colony-stimulating factor receptor. Biochim Biophys Acta. 1998 Nov 19;1448(1):70-6.
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| REF 2 |
Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor. J Biol Chem. 2004 Jan 2;279(1):326-40.
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