| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T02562 | ||||
| Target Name | Prostaglandin E synthase (PTGES) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | L-655240 | Drug Info | IC50 = 2600 nM | [1] | |
| References | |||||
| REF 1 | Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3352-5. | ||||
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