| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T13057 | ||||
| Target Name | Protein-tyrosine phosphatase SHP-2 (PTPN11) | ||||
| Type of Target |
Clinical trial |
||||
| Drug Potency against Target | Drug Info | IC50 = 300 nM | [1] | ||
| References | |||||
| REF 1 | Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds. J Med Chem. 2008 Aug 28;51(16):4948-56. | ||||
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