Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T19433 | ||||
Target Name | Glutathione-dependent PGD synthase (HPGDS) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Praziquantel | Drug Info | IC50 = 3300000 nM | [1] | |
References | |||||
REF 1 | X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. BMC Struct Biol. 2007 Jun 26;7:42. | ||||
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