Target Validation Information
TTD ID T19433
Target Name Glutathione-dependent PGD synthase (HPGDS)
Type of Target
Successful
Drug Potency against Target Praziquantel Drug Info IC50 = 3300000 nM [1]
References
REF 1 X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. BMC Struct Biol. 2007 Jun 26;7:42.

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