| Target Validation Information | |||||
|---|---|---|---|---|---|
| TTD ID | T40016 | ||||
| Target Name | Glucocorticoid receptor (NR3C1) | ||||
| Type of Target |
Successful |
||||
| Drug Potency against Target | GW685698X | Drug Info | IC50 = 69000 nM | [2] | |
| BAY 86-5044 | Drug Info | IC50 = 16 nM | [1] | ||
| References | |||||
| REF 1 | Synthesis and biological activity of a novel, highly potent progesterone receptor antagonist. J Med Chem. 2000 Dec 28;43(26):5010-6. | ||||
| REF 2 | Structure-activity relationships of selective GABA uptake inhibitors. Curr Top Med Chem. 2006;6(17):1861-82. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.