Target Validation Information
TTD ID T75570
Target Name Yes tyrosine kinase (YES)
Type of Target
Clinical trial
Drug Potency against Target TG-100435 Drug Info Ki = 12.9 nM [1]
References
REF 1 Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine--a potent, orally active Src kinas... Bioorg Med Chem Lett. 2007 Feb 1;17(3):602-8.

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