Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T93440 | ||||
Target Name | Interleukin 6 receptor (IL6R) | ||||
Type of Target |
Successful |
||||
Drug Potency against Target | Tocilizumab | Drug Info | Kd = 2.54+/-0.12 nM | [1] | |
References | |||||
REF 1 | Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family. Int Immunopharmacol. 2005 Nov;5(12):1731-40. | ||||
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