Resistance mutation info of target
| Target General Information | ||||||||||||||||||
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| Target ID | T24634 | |||||||||||||||||
| Target Name | Bacterial Enoylpyruvate transferase (murA) | |||||||||||||||||
| Gene Name | murA | |||||||||||||||||
| Species | Escherichia coli | |||||||||||||||||
| UniProt ID | MURA_ECOLI | |||||||||||||||||
| Sequence |
MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQL GAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGAR PVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTT IIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLV AAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHP AFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKL SGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE [Escherichia coli] |
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| Drug and Corresponding Resistance Mutations | ||||||||||||||||||
| Mutation Info | Missense: D369N | |||||||||||||||||
| Drugs |
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| Mutation Info | Missense: L370I | |||||||||||||||||
| Drugs |
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| References | ||||||||||||||||||
| REF 1 | CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database. Nucleic Acids Res. 2017 Jan 4;45(D1):D566-D573. | |||||||||||||||||
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