Drug General Information
Drug ID
DX0MNR
Drug Name
(S)-N-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethyl]-2-(naphthalene-1-sulfonylamino)-propionamide
Synonyms
CHEMBL342189
Indication Discovery agent Investigative [1587926]
Formula
C24H23N3O4S
Canonical SMILES
C[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C=O
InChI
InChI=1S/C24H23N3O4S/c1-16(27-32(30,31)23-12-6-8-17-7-2-3-10-21(17)23)24(29)26-19(15-28)13-18-14-25-22-11-5-4-9-20(18)22/h2-12,14-16,19,25,27H,13H2,1H3,(H,26,29)/t16-,19+/m0/s1
InChIKey
UNLVZLHANKRKSG-QFBILLFUSA-N
Target and Pathway
Target(s) Cathepsin L Target Info [1587926]
Cathepsin B Target Info [1587926]
KEGG Pathway Lysosome
Phagosome
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritishsa04142:Lysosome
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling PathwayNetPath_11:TCR Signaling Pathway
IL2 Signaling Pathway
Reactome Endosomal/Vacuolar pathway
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentationR-HSA-1442490:Collagen degradation
MHC class II antigen presentation
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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