Drug General Information
Drug ID
DX1EHJ
Drug Name
SID174007069
Synonyms
CHEMBL197194
Indication Discovery agent Investigative [1587926]
Formula
C20H18FNO4
Canonical SMILES
COc1cccc(c1)c2ccc(NC(=O)C3=C(CCC3)C(=O)O)c(F)c2
InChI
InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2,4-5,8-11H,3,6-7H2,1H3,(H,22,23)(H,24,25)
InChIKey
XPRDUGXOWVXZLL-UHFFFAOYSA-N
Target and Pathway
Target(s) Dihydroorotate dehydrogenase, mitochondrial Target Info [1587926]
Interleukin-17 Target Info [1587926]
KEGG Pathway Pyrimidine metabolism
Metabolic pathwayshsa04060:Cytokine-cytokine receptor interaction
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Interleukin signaling pathway
Pathway Interaction Database IL27-mediated signaling events
IL23-mediated signaling events
PathWhiz Pathway Pyrimidine Metabolism
Reactome Pyrimidine biosynthesis
WikiPathways Metabolism of nucleotidesWP69:TCR Signaling Pathway
Allograft Rejection
IL17 signaling pathway
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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