Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX1TCE
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| Drug Name |
1-((3,5-dichlorophenyl)(p-tolyl)methylene)thiosemicarbazide
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| Synonyms |
CHEMBL261438
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C15H13Cl2N3S
|
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| Canonical SMILES |
Cc1ccc(cc1)\\C(=N/NC(=S)N)\\c2cc(Cl)cc(Cl)c2
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| InChI |
InChI=1S/C15H13Cl2N3S/c1-9-2-4-10(5-3-9)14(19-20-15(18)21)11-6-12(16)8-13(17)7-11/h2-8H,1H3,(H3,18,20,21)/b19-14+
|
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| InChIKey |
SWWHTWZROMUIHA-XMHGGMMESA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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