Drug General Information
Drug ID
DX2IT5
Drug Name
(2-(4-(trifluoromethoxy)benzyl)phenyl)-N,N-dimethylmethanamine
Synonyms
CHEMBL492815
Indication Discovery agent Investigative [1587926]
Formula
C17H18F3NO
Canonical SMILES
CN(C)Cc1ccccc1Cc2ccc(OC(F)(F)F)cc2
InChI
InChI=1S/C17H18F3NO/c1-21(2)12-15-6-4-3-5-14(15)11-13-7-9-16(10-8-13)22-17(18,19)20/h3-10H,11-12H2,1-2H3
InChIKey
KEIRXXIACQJSMU-UHFFFAOYSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1B receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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