Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2KMY
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| Drug Name |
4'-(1-Methyl-piperidin-4-yloxy)-biphenyl-4-carboxylic acid [1-(cyanomethyl-carbamoyl)-cyclohexyl]-amide
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| Synonyms |
CHEMBL200426
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H34N4O3
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| Canonical SMILES |
CN1CCC(CC1)Oc2ccc(cc2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
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| InChI |
InChI=1S/C28H34N4O3/c1-32-19-13-25(14-20-32)35-24-11-9-22(10-12-24)21-5-7-23(8-6-21)26(33)31-28(15-3-2-4-16-28)27(34)30-18-17-29/h5-12,25H,2-4,13-16,18-20H2,1H3,(H,30,34)(H,31,33)
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| InChIKey |
BWFJISBMXNYRDL-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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