Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3QQE
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| Drug Name |
N-(4-(4-(3,4-dichlorophenoxy)-3-((methylamino)methyl)phenyl)but-3-ynyl)-N-methylcyclopropanamine
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| Synonyms |
CHEMBL237513
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| Indication | Discovery agent | Investigative | [1] | ||
| Formula |
C22H24Cl2N2O
|
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| Canonical SMILES |
CNCc1cc(ccc1Oc2ccc(Cl)c(Cl)c2)C#CCCN(C)C3CC3
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| InChI |
InChI=1S/C22H24Cl2N2O/c1-25-15-17-13-16(5-3-4-12-26(2)18-7-8-18)6-11-22(17)27-19-9-10-20(23)21(24)14-19/h6,9-11,13-14,18,25H,4,7-8,12,15H2,1-2H3
|
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| InChIKey |
VTPCFOYQLMVYRO-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Histamine H3 receptor | Target Info | [1] | ||
| Sodium-dependent serotonin transporter | Target Info | [1] | |||
| KEGG Pathway | Neuroactive ligand-receptor interactionhsa04726:Serotonergic synapse | ||||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | 5HT1 type receptor mediated signaling pathway | ||||
| 5HT2 type receptor mediated signaling pathway | |||||
| 5HT3 type receptor mediated signaling pathway | |||||
| 5HT4 type receptor mediated signaling pathway | |||||
| Reactome | Histamine receptors | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP727:Monoamine Transport | |||||
| SIDS Susceptibility Pathways | |||||
| NRF2 pathway | |||||
| Synaptic Vesicle Pathway | |||||
| Serotonin Transporter Activity | |||||
| References | |||||
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 | ||||
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