Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4A4J
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| Drug Name |
(S)-N-(1-(cyanomethylamino)-3-(3-(1-methyl-1H-pyrazol-4-yl)phenyl)-1-oxopropan-2-yl)benzamide
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| Synonyms |
CHEMBL560736
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H21N5O2
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| Canonical SMILES |
Cn1cc(cn1)c2cccc(C[C@H](NC(=O)c3ccccc3)C(=O)NCC#N)c2
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| InChI |
InChI=1S/C22H21N5O2/c1-27-15-19(14-25-27)18-9-5-6-16(12-18)13-20(22(29)24-11-10-23)26-21(28)17-7-3-2-4-8-17/h2-9,12,14-15,20H,11,13H2,1H3,(H,24,29)(H,26,28)/t20-/m0/s1
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| InChIKey |
VSNZDNFCCVCSSH-FQEVSTJZSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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