Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4FSN
|
||||
| Drug Name |
(R)-N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(2-(3-aminopyrrolidin-1-yl)thiazol-4-yl)benzamide
|
||||
| Synonyms |
CHEMBL200507
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H28N6O2S
|
||||
| Canonical SMILES |
N[C@@H]1CCN(C1)c2nc(cs2)c3ccc(cc3)C(=O)NC4(CCCCC4)C(=O)NCC#N
|
||||
| InChI |
InChI=1S/C23H28N6O2S/c24-11-12-26-21(31)23(9-2-1-3-10-23)28-20(30)17-6-4-16(5-7-17)19-15-32-22(27-19)29-13-8-18(25)14-29/h4-7,15,18H,1-3,8-10,12-14,25H2,(H,26,31)(H,28,30)/t18-/m1/s1
|
||||
| InChIKey |
HUKHYYRAYGNCKY-GOSISDBHSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.