Drug General Information
Drug ID
DX4LZK
Drug Name
(1S,2S)-2-bromo-7-oxa-5-aza-bicyclo[3.2.1]octan-6-one
Synonyms
CHEMBL397972
Indication Discovery agent Investigative [1587926]
Formula
C6H8BrNO2
Canonical SMILES
Br[C@H]1CCN2C[C@@H]1OC2=O
InChI
InChI=1S/C6H8BrNO2/c7-4-1-2-8-3-5(4)10-6(8)9/h4-5H,1-3H2/t4-,5-/m0/s1
InChIKey
VVSXVRNUMNINTL-WHFBIAKZSA-N
Target and Pathway
Target(s) Cathepsin L Target Info [1587926]
Cathepsin B Target Info [1587926]
KEGG Pathway Lysosome
Phagosome
Antigen processing and presentation
Proteoglycans in cancer
Rheumatoid arthritishsa04142:Lysosome
NetPath Pathway IL4 Signaling Pathway
TGF_beta_Receptor Signaling PathwayNetPath_11:TCR Signaling Pathway
IL2 Signaling Pathway
Reactome Endosomal/Vacuolar pathway
Collagen degradation
Degradation of the extracellular matrix
Trafficking and processing of endosomal TLR
Assembly of collagen fibrils and other multimeric structures
MHC class II antigen presentationR-HSA-1442490:Collagen degradation
MHC class II antigen presentation
WikiPathways Primary Focal Segmental Glomerulosclerosis FSGS
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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