| Drug General Information |
| Drug ID |
DX5E3S
|
| Drug Name |
(3,4-dichlorophenyl)(2-((dimethylamino)methyl)phenyl)methanone
|
| Synonyms |
(3,4-Dichlorophenyl)(2-((Dimethylamino)Methyl)Phenyl)Methanone; CHEMBL453493
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Formula |
C16H15Cl2NO
|
| Canonical SMILES |
CN(C)Cc1ccccc1C(=O)c2ccc(Cl)c(Cl)c2
|
| InChI |
InChI=1S/C16H15Cl2NO/c1-19(2)10-12-5-3-4-6-13(12)16(20)11-7-8-14(17)15(18)9-11/h3-9H,10H2,1-2H3
|
| InChIKey |
RYTIZBPXUHTIDS-UHFFFAOYSA-N
|
| Target and Pathway |
| Target(s) |
5-hydroxytryptamine 1B receptor |
Target Info |
|
[1]
|
|---|
| Sodium-dependent serotonin transporter |
Target Info |
|
[1]
|
|
KEGG Pathway
|
cAMP signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Serotonergic synapsehsa04726:Serotonergic synapse
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
|
|
5HT2 type receptor mediated signaling pathway
|
|
5HT3 type receptor mediated signaling pathway
|
|
5HT4 type receptor mediated signaling pathway
|
|
Reactome
|
Serotonin receptors
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
Serotonin HTR1 Group and FOS Pathway
|
|
Monoamine GPCRs
|
|
GPCRs, Class A Rhodopsin-like
|
|
GPCR ligand binding
|
|
GPCR downstream signalingWP727:Monoamine Transport
|
|
SIDS Susceptibility Pathways
|
|
NRF2 pathway
|
|
Synaptic Vesicle Pathway
|
|
Serotonin Transporter Activity
|
| References |
| REF 1 | URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017 |
|---|
